Jacques J D M van Lankveld, Marieke Dewitte, Erick Janssen, Peter Verboon
{"title":"Attachment orientation and sexual excitation and inhibition independently predict sexual desire and sexual arousal, but their interaction does not.","authors":"Jacques J D M van Lankveld, Marieke Dewitte, Erick Janssen, Peter Verboon","doi":"10.1038/s41443-026-01307-7","DOIUrl":"https://doi.org/10.1038/s41443-026-01307-7","url":null,"abstract":"<p><p>In this cross-sectional study we investigated whether attachment orientation moderated the associations between sexual excitation and inhibition and sexual desire and arousal. A convenience sample of 358 participants (242 women and 116 men; mean age: 37.6 ± 12.0) completed online questionnaires including the Sexual Inhibition/Sexual Excitation Scales-Short Form, the Experiences in Close Relationships scale, the Female Sexual Function Index (women only), and the International Index of Erectile Function (men only). Associations were tested using multiple linear regression analysis. Sexual excitation/inhibition (sexual desire: B<sub>SES</sub> = .207, p = .044, B<sub>SIS1</sub> = -.473, p < .001; sexual arousal: B<sub>SIS1</sub> = -.419, p < .001) and attachment anxiety (sexual arousal: B<sub>ANX</sub> = -.207, p < .001) independently predicted part of the variance in sexual desire and arousal. Relationship duration negatively predicted level of sexual desire (B = -.023, p < .001), while male gender positively predicted sexual desire (B = .634, p < .001) and sexual arousal (B = .487, p < .001). The associations between sexual excitation/inhibition and sexual desire and arousal were not moderated by attachment orientation. Further research into the interaction of sexual excitation and sexual inhibition proneness and adult attachment orientation as determinants of sexual desire and arousal seems warranted.</p>","PeriodicalId":14068,"journal":{"name":"International Journal of Impotence Research","volume":" ","pages":""},"PeriodicalIF":2.5,"publicationDate":"2026-06-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148351905","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Alfonso Bruzzone, Maurizio D'Anna, Josep Torremadé
{"title":"Comment on: Application of gelatin sponge (Gelfoam®) as a hemostatic agent in inflatable penile prosthesis implantation.","authors":"Alfonso Bruzzone, Maurizio D'Anna, Josep Torremadé","doi":"10.1038/s41443-026-01309-5","DOIUrl":"10.1038/s41443-026-01309-5","url":null,"abstract":"","PeriodicalId":14068,"journal":{"name":"International Journal of Impotence Research","volume":" ","pages":""},"PeriodicalIF":2.5,"publicationDate":"2026-06-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148345246","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Challenging the paradigm: what is vasculogenic erectile dysfunction?","authors":"Stefan Buntrock, Nicolas Diehm","doi":"10.1038/s41443-026-01311-x","DOIUrl":"10.1038/s41443-026-01311-x","url":null,"abstract":"","PeriodicalId":14068,"journal":{"name":"International Journal of Impotence Research","volume":" ","pages":""},"PeriodicalIF":2.5,"publicationDate":"2026-06-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148338517","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Maximilian J Rabil, Ellen M Cahill, Stanton C Honig
{"title":"It Comes at Night: A Nocturnal Emissions Historical Review.","authors":"Maximilian J Rabil, Ellen M Cahill, Stanton C Honig","doi":"10.1038/s41443-026-01310-y","DOIUrl":"https://doi.org/10.1038/s41443-026-01310-y","url":null,"abstract":"<p><p>Nocturnal emissions are a normal biologic function of sexual arousal and ejaculation during sleep, often beginning in puberty. Historically, views on nocturnal emissions have varied, but they are an important aspect of sexual culture, as they may represent one of a person's earliest encounters with sexuality, often beginning during puberty. We sought to characterize the sexual culture views on nocturnal seminal emissions in the early 1900s and compare and contrast that to the views of the modern era as it relates to destigmatization of sexual health. A non-systematic review was performed to characterize historical views on nocturnal emissions, including cultural and religious perspectives. Modern perspectives on social media platform TikTok were also reviewed and compared to historical viewpoints. Throughout history, views on nocturnal emissions have varied, from accepting as a biological function to deeply stigmatized with sinful connotations. There remain medically unfounded claims about nocturnal emissions today highlighting an opportunity for sexual medical care providers to clarify and destigmatize the topic particularly for adolescents who may be most impressionable as they experience nocturnal emissions for the first time.</p>","PeriodicalId":14068,"journal":{"name":"International Journal of Impotence Research","volume":" ","pages":""},"PeriodicalIF":2.5,"publicationDate":"2026-06-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148338554","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Metin Mod, Emin Taha Keskin, Osman Can, Çağrı Şevik, Halil Lutfi Canat
{"title":"Erectile and ejaculatory outcomes after penile fracture repair: a comparative analysis of absorbable vs non-absorbable sutures.","authors":"Metin Mod, Emin Taha Keskin, Osman Can, Çağrı Şevik, Halil Lutfi Canat","doi":"10.1038/s41443-026-01313-9","DOIUrl":"https://doi.org/10.1038/s41443-026-01313-9","url":null,"abstract":"<p><p>This study aimed to compare the effects of absorbable and non-absorbable sutures on postoperative erectile function, ejaculatory function and sexual satisfaction in patients undergoing penile fracture repair. In this single-center retrospective cohort study, 90 patients who underwent surgical treatment for penile fracture between 2020 and 2024 were included. Patients were grouped by suture type, with absorbable sutures used in 53 patients (58.9%) and non-absorbable sutures used in 37 patients (41.1%). Functional outcomes were assessed using the International Index of Erectile Function-5, intravaginal ejaculatory latency time and Index of Sexual Satisfaction at baseline and at 6 and 12 months postoperatively. Baseline characteristics and functional scores were similar between groups. In the absorbable suture group, median International Index of Erectile Function-5 scores showed a statistically significant change at 6 months compared to baseline (24 (IQR: 23 - 26) vs. 24 (IQR: 23 - 25); p = 0.021), but no significant difference was observed at 12 months (24 (IQR: 23 - 25); p = 0.069). In the absorbable group, median intravaginal ejaculatory latency time showed a statistically significant change from baseline at both 6 months (240 (IQR: 180 - 300) vs. 240 (IQR: 200 - 300); p = 0.011) and 12 months (240 (IQR: 180 - 300) vs. 240 (IQR: 205 - 300); p = 0.006). In the non-absorbable group, median intravaginal ejaculatory latency time increased from 240 (IQR: 180 - 330) to 300 (IQR: 200 - 360) at 6 months (p = 0.023) and remained at 300 (IQR: 240 - 360) at 12 months (p = 0.026). Palpable penile nodules were more frequent in the non-absorbable group (24.3% vs. 3.8%; p = 0.006). Early postoperative changes in erectile function were minimal and long-term erectile, ejaculatory and sexual satisfaction outcomes were comparable between absorbable and non-absorbable sutures. Non-absorbable sutures are linked to more palpable nodules. These findings may help guide suture selection.</p>","PeriodicalId":14068,"journal":{"name":"International Journal of Impotence Research","volume":" ","pages":""},"PeriodicalIF":2.5,"publicationDate":"2026-06-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148308031","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Comment on: GLP-1 receptor agonists and male sexual health: translating cardiometabolic benefits into erectile outcomes.","authors":"Franco Grimolizzi","doi":"10.1038/s41443-026-01312-w","DOIUrl":"10.1038/s41443-026-01312-w","url":null,"abstract":"","PeriodicalId":14068,"journal":{"name":"International Journal of Impotence Research","volume":" ","pages":""},"PeriodicalIF":2.5,"publicationDate":"2026-06-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148317011","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Comment on: cardiovascular and prostate cancer risk associated to testosterone replacement therapy-a systematic review and meta-analysis of 41 randomized controlled trials.","authors":"Andrea Sansone, Emmanuele A Jannini","doi":"10.1038/s41443-026-01304-w","DOIUrl":"https://doi.org/10.1038/s41443-026-01304-w","url":null,"abstract":"","PeriodicalId":14068,"journal":{"name":"International Journal of Impotence Research","volume":" ","pages":""},"PeriodicalIF":2.5,"publicationDate":"2026-06-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148301437","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Female genital cutting and cosmetic genital surgery: a narrative synthesis of global practices, motivations, and the influence of aesthetic ideals.","authors":"Oluchukwu Loveth Obiora","doi":"10.1038/s41443-026-01308-6","DOIUrl":"https://doi.org/10.1038/s41443-026-01308-6","url":null,"abstract":"<p><p>This study advances current discourse by introducing a novel analytic framework-the global quest for genital beauty-to clarify how sociocultural ideals of vulva appearance shape motivations, meanings, and policy responses surrounding female genital cutting (FGC) and female genital cosmetic surgery (FGCS). Using a theory‑informed narrative synthesis of literature published between 2015 and August 2025 across PubMed, Scopus, and Web of Science, supplemented by seminal theoretical works and agency reports. The analysis demonstrates that although FGC and FGCS arise within distinct sociocultural systems, both are influenced by gendered expectations about bodily propriety and aesthetic norms. The review identifies substantial variations within each category: FGC encompasses procedures with differing degrees of tissue alteration and risk, while FGCS includes a growing array of elective cosmetic interventions shaped by media, pornography, and clinical marketing. An estimated 230 million women and girls in countries with available survey data have undergone FGC, requiring a 27‑fold acceleration in progress to meet the 2030 Sustainable Development Goal target, while clinical organizations report rising demands for FGCS despite limited evidence of benefit and acknowledged risks. By applying the genital beauty framework, this study reframes the comparison between FGC and FGCS, highlighting both their divergences and their shared entanglement with globalized beauty norms. This perspective supports more precise ethical, clinical, and policy guidance, including rights‑based strategies to accelerate abandonment of FGC and reduce non‑therapeutic demand for FGCS through regulation, norm‑change interventions, and education about genital diversity.</p>","PeriodicalId":14068,"journal":{"name":"International Journal of Impotence Research","volume":" ","pages":""},"PeriodicalIF":2.5,"publicationDate":"2026-06-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148301608","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Priapism: how far have we come and the road ahead","authors":"Wai Gin Lee, David Ralph","doi":"10.1038/s41443-026-01302-y","DOIUrl":"10.1038/s41443-026-01302-y","url":null,"abstract":"","PeriodicalId":14068,"journal":{"name":"International Journal of Impotence Research","volume":"38 9","pages":"1-3"},"PeriodicalIF":2.5,"publicationDate":"2026-06-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.nature.comhttps://www.nature.com/articles/s41443-026-01302-y.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148301622","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Ardie Barry Sailis, Muhamad Alfakri Mat Noh, Bey Fen Leo, Farid Nazer Faruqu, Hui Yin Yow, Anne Yee, Maw Shin Sim
{"title":"E-cigarettes and erectile dysfunction: biological mechanisms and research challenges.","authors":"Ardie Barry Sailis, Muhamad Alfakri Mat Noh, Bey Fen Leo, Farid Nazer Faruqu, Hui Yin Yow, Anne Yee, Maw Shin Sim","doi":"10.1038/s41443-026-01300-0","DOIUrl":"https://doi.org/10.1038/s41443-026-01300-0","url":null,"abstract":"<p><p>Electronic cigarettes are widely promoted as harm-reduction alternatives to conventional tobacco smoking, yet their potential effects on male sexual health remain incompletely characterised. Erectile dysfunction is a predominantly vascular condition with important neuroendocrine regulation and is highly sensitive to endothelial injury, oxidative stress, hormonal imbalance, and autonomic dysregulation, all of which may plausibly be influenced by electronic cigarette use. Despite increasing global prevalence, direct evidence linking electronic cigarette use to erectile dysfunction remains limited. This narrative review synthesises current experimental, clinical, and epidemiological evidence examining the association between electronic cigarette use and erectile dysfunction, with emphasis on underlying biological mechanisms and key research gaps. Emerging evidence implicates endothelial dysfunction, impaired nitric oxide bioavailability, oxidative stress, inflammation, hormonal disturbance, autonomic imbalance, sleep disturbance, and exposure to aerosolised substances and metals as interconnected pathways that may contribute to erectile dysfunction. Overall, the existing literature remains preliminary and largely hypothesis-generating, with no longitudinal studies capable of establishing causality or dose-response relationships. Well-designed prospective studies are required to clarify the long-term sexual health outcomes associated with electronic cigarette use.</p>","PeriodicalId":14068,"journal":{"name":"International Journal of Impotence Research","volume":" ","pages":""},"PeriodicalIF":2.5,"publicationDate":"2026-06-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148258240","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}