{"title":"Mpox: what sexual health physicians need to know?","authors":"Ahmet Çağkan İnkaya","doi":"10.1038/s41443-024-00964-w","DOIUrl":"10.1038/s41443-024-00964-w","url":null,"abstract":"Monkeypox virus (MPXV) is another zoonotic virus spilled over to the man and resulted in pandemic. World Health Organization declared it as a ‘Public Health Emergency of International Concern (PHEIC) on July 22, 2022. Mpox affected over 95226 individuals among them claimed the lives of 185. Despite the fact that Mpox is generally mild and self-limited, immunocompromised people with low CD4 counts may experience severe disease course. Management of Mpox patients has three pillars. First symptomatic approach includes pain management, prophylaxis for secondary infections and when needed effective treatment of superinfections. Second, vaccines developed against smallpox can be used in preexposure or postexposure prophylaxis strategies against Mpox. Third, current antiviral options include tecovirimat, cidofovir and birincidofovir all of which have been recommended relying on experience from animal studies, clinical case reports or case series. Results of well-planned randomized control trials are not available. Occupational exposure to MPXV is especially a manageable risk for health care workers. Prevention of Mpox also requires risk communication with vulnerable population and their involvement in mitigation efforts.","PeriodicalId":14068,"journal":{"name":"International Journal of Impotence Research","volume":"36 6","pages":"556-561"},"PeriodicalIF":2.8,"publicationDate":"2024-08-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.nature.com/articles/s41443-024-00964-w.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141995713","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Blake E. Johnson, Brian T. Langford, Maia E. VanDyke, Ethan L. Matz, Grayden S. Cook, Bryce P. Franzen, Allen F. Morey
{"title":"Long-term experience with AMS-700 CXR inflatable penile prosthesis in high-risk patients with corporal fibrosis","authors":"Blake E. Johnson, Brian T. Langford, Maia E. VanDyke, Ethan L. Matz, Grayden S. Cook, Bryce P. Franzen, Allen F. Morey","doi":"10.1038/s41443-024-00962-y","DOIUrl":"10.1038/s41443-024-00962-y","url":null,"abstract":"Despite the widespread use of narrow diameter inflatable penile prosthesis (IPP) cylinders in patients with corporal fibrosis, outcomes data is sparse. We evaluated patients who underwent IPP placement with AMS™ 700 Controlled Expansion Restricted (CXR) cylinders from 2007–2021. Patient characteristics, device details, and surgical outcomes were assessed. A non-validated questionnaire was also distributed to patients to assess satisfaction. Among 982 IPPs placed over the study period at our institution, 49 (5.0%) used CXR cylinders. Indications for narrow cylinders: prior explant for infection (67.3%), ischemic priapism (16.3%), and idiopathic fibrosis (16.3%). Median corporal length was 19 cm (IQR 17–21 cm). Discordant intraoperative corporal measurements (24.5%) and RTE lengths (26.5%) were common. Post-operative complications occurred in 8 patients (16.3%) and included 3 infections (6.1%), 2 cylinder herniations (4.1%), 2 mechanical failures (4.1%), and one case of glans necrosis (2.0%). Five of these (10.2%) required explantation, while 4 (8.2%) were managed with revision. Over the follow-up period, 73.5% of patients reported satisfaction with rigidity. Primary drivers of dissatisfaction were perceived loss of penile length and girth. The AMS™ 700 CXR is a useful tool for challenging corporal fibrosis cases and shows acceptable surgical outcomes with moderate patient acceptability.","PeriodicalId":14068,"journal":{"name":"International Journal of Impotence Research","volume":"37 1","pages":"66-71"},"PeriodicalIF":2.8,"publicationDate":"2024-08-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141995712","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Dan Shan, Yuming Song, Yanyi Zhang, Pincheng Luo, Zijie Dai, Zhihao Dai
{"title":"Associations between masturbation frequency, anxiety, and sleep disturbances during the COVID-19 era.","authors":"Dan Shan, Yuming Song, Yanyi Zhang, Pincheng Luo, Zijie Dai, Zhihao Dai","doi":"10.1038/s41443-024-00961-z","DOIUrl":"10.1038/s41443-024-00961-z","url":null,"abstract":"<p><p>The COVID-19 pandemic has markedly influenced people's lifestyle and sexual behaviors, including masturbation patterns. This study delved into how masturbation frequency could impact anxiety levels, sleep quality, and somatic symptoms post-masturbation among Chinese adults during this period. From December 2022 to January 2023, we conducted a cross-sectional survey, gathering data via WenJuanXing, a leading online survey platform in China. This platform facilitated the recruitment of a diverse cohort, spanning various age groups and geographical locations. Masturbation frequency among participants was subjectively categorized into three levels: 'lesser' (a few times over the past year), 'moderate' (once to three times a month), and 'greater' (weekly to almost daily). To assess anxiety levels and sleep quality, we employed the Generalized Anxiety Disorder 7-item (GAD-7) scale and the Pittsburgh Sleep Quality Index (PSQI), respectively. Among 1500 participants, we received 1423 valid responses. Among these, 65% (n = 930) reported engaging in masturbation in the past year, of whom 87.5% reported subjectively experiencing various levels of fatigue post-masturbation. These 930 responses were subsequently analyzed in-depth (e.g., non-parametric test and pathway analysis), with ages ranging from 18 to 54 years (mean age = 30.5, SD = 7.42). Notably, our findings indicate that participants with greater masturbation frequency exhibited higher anxiety levels [GAD-7 median score: 6 (lesser) vs. 4 (moderate) vs. 8 (greater), p < 0.001, Cohen's f = 0.41] and poorer sleep quality [PSQI median score: 5 (lesser) vs. 4 (moderate) vs. 7 (greater), p < 0.001, Cohen's f = 0.46]. A rough positive correlation between masturbation frequency and PSQI score was also observed (β = 0.16, p < 0.001). These results suggest potential mental and sleep benefits at moderate frequencies, especially in contrast to greater frequencies. However, the cross-sectional design and subjective categorization of masturbation frequency in our study limit our ability to draw definitive causal conclusions. These limitations highlight the need for future longitudinal research employing more precise categorizations of masturbation behavior, such as frequency, to delve deeper into these relationships and understand their underlying mechanisms.</p>","PeriodicalId":14068,"journal":{"name":"International Journal of Impotence Research","volume":" ","pages":""},"PeriodicalIF":2.8,"publicationDate":"2024-08-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141916636","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Comment on: Prescribing semaglutide for weight loss in non-diabetic, obese patients is associated with an increased risk of erectile dysfunction: a TriNetX database study.","authors":"Selman Unal","doi":"10.1038/s41443-024-00960-0","DOIUrl":"https://doi.org/10.1038/s41443-024-00960-0","url":null,"abstract":"","PeriodicalId":14068,"journal":{"name":"International Journal of Impotence Research","volume":" ","pages":""},"PeriodicalIF":2.8,"publicationDate":"2024-08-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141912546","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Nikolaos Pyrgidis, Dimitrios Kalyvianakis, Ioannis Mykoniatis, Dimitrios Hatzichristou
{"title":"The recommended treatment protocol for low-intensity shockwave therapy based on the severity of erectile dysfunction.","authors":"Nikolaos Pyrgidis, Dimitrios Kalyvianakis, Ioannis Mykoniatis, Dimitrios Hatzichristou","doi":"10.1038/s41443-024-00959-7","DOIUrl":"10.1038/s41443-024-00959-7","url":null,"abstract":"","PeriodicalId":14068,"journal":{"name":"International Journal of Impotence Research","volume":" ","pages":""},"PeriodicalIF":2.8,"publicationDate":"2024-08-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141897402","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Commentary to the article \"Compulsive sexual behavior and paraphilic interests in adults with chronic tic disorders and Tourette syndrome: a survey-based study\".","authors":"Natalia Szejko, Anna Dunalska, Kamila Saramak","doi":"10.1038/s41443-024-00957-9","DOIUrl":"https://doi.org/10.1038/s41443-024-00957-9","url":null,"abstract":"","PeriodicalId":14068,"journal":{"name":"International Journal of Impotence Research","volume":" ","pages":""},"PeriodicalIF":2.8,"publicationDate":"2024-07-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141859730","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Supanut Lumbiganon, Muhammed A. Moukhtar Hammad, Babak Azad, Faysal A. Yafi
{"title":"A narrative review of initial treatment for ischemic priapism","authors":"Supanut Lumbiganon, Muhammed A. Moukhtar Hammad, Babak Azad, Faysal A. Yafi","doi":"10.1038/s41443-024-00951-1","DOIUrl":"https://doi.org/10.1038/s41443-024-00951-1","url":null,"abstract":"<p>Priapism is a rare condition characterized by prolonged and often painful penile erection unrelated to sexual stimulation. Ischemic priapism, the most common subtype, requires immediate attention to prevent irreversible damage to erectile tissue. This narrative review explores the initial management strategies for ischemic priapism. Intracavernosal phenylephrine injection and aspiration with or without irrigation are recommended as first-line treatments, with alternative options available depending on clinical settings and patient factors. While guidelines offer clear recommendations for priapism lasting more than 4 h, management of shorter-duration cases remains challenging due to limited evidence.</p>","PeriodicalId":14068,"journal":{"name":"International Journal of Impotence Research","volume":"58 1","pages":""},"PeriodicalIF":2.6,"publicationDate":"2024-07-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141775087","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
R Omer Yazar, Muhammed A M Hammad, David W Barham, Babak Azad, Faysal A Yafi
{"title":"Successful treatment of hard flaccid syndrome with multimodal therapy: a case report study.","authors":"R Omer Yazar, Muhammed A M Hammad, David W Barham, Babak Azad, Faysal A Yafi","doi":"10.1038/s41443-024-00955-x","DOIUrl":"https://doi.org/10.1038/s41443-024-00955-x","url":null,"abstract":"<p><p>Our article outlines a case study assessing the use of low-intensity shock wave therapy (LiSWT) for managing Hard Flaccid Syndrome (HFS). Given the absence of standardized treatments for HFS, LiSWT could serve as an additional tool in the treatment arsenal. The case involved a 36-year-old male presenting HFS, low libido, chronic pain, and erectile dysfunction. Treatment comprised phosphodiesterase type 5 inhibitor (PDE5-I), physical therapy, and LiSWT. Following six sessions, the patient experienced regression of bothersome symptoms and improved erections. A 2-year follow-up revealed sustained symptom relief. LiSWT presents a non-invasive means of inducing mechanical stress and microtrauma in targeted tissues, fostering neovascularization and potentially enhancing blood supply. The integration of LiSWT with PDE5-I and physical therapy suggests a potential avenue for effective HFS management. Nevertheless, further systematic research is essential to validate the therapy's benefits and assess, if any, potential drawbacks.</p>","PeriodicalId":14068,"journal":{"name":"International Journal of Impotence Research","volume":" ","pages":""},"PeriodicalIF":2.8,"publicationDate":"2024-07-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141758518","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Angelo Territo, Mario Belmonte, Andrea Cocci, Eduard Ruiz-Castañe, Fabio Castiglione, Guglielmo Mantica, Thomas Prudhomme, Alessio Pecoraro, Alberto Piana, Beatriz Bañuelos Marco, Muhammet Irfan Dönmez, Francesco Esperto, Giorgio Ivan Russo, Riccardo Campi, Alberto Breda, Alicia López-Abad, On behalf of the Young Academic Urologists (YAU) Kidney Transplantation working group
{"title":"Is it safe to implant a penile prosthesis in a solid organ transplant recipient? A systematic review","authors":"Angelo Territo, Mario Belmonte, Andrea Cocci, Eduard Ruiz-Castañe, Fabio Castiglione, Guglielmo Mantica, Thomas Prudhomme, Alessio Pecoraro, Alberto Piana, Beatriz Bañuelos Marco, Muhammet Irfan Dönmez, Francesco Esperto, Giorgio Ivan Russo, Riccardo Campi, Alberto Breda, Alicia López-Abad, On behalf of the Young Academic Urologists (YAU) Kidney Transplantation working group","doi":"10.1038/s41443-024-00939-x","DOIUrl":"10.1038/s41443-024-00939-x","url":null,"abstract":"Solid organ transplant recipients exhibit an elevated incidence of erectile dysfunction, attributed to comorbidities and specific factors associated with organ failure. While treatment mirrors the general population’s, response rates are lower, and there is a heightened concern about implanting a penile prosthesis in immunocompromised patients due to the potential occurrence of severe complications. The aim of this study was to assess the safety of penile prostheses in this population. Among fourteen included studies, ten were case reports or series of cases, and four were non randomized case-control studies with non-transplanted patients as controls. Complications affected 34 patients (11.15%), with mechanical device failures in 18 cases (5.9%) and infections in 13 cases (4.26%). Most infections required hospitalization, antibiotic treatment, and prosthesis removal, with two cases of life-threatening Fournier’s gangrene. Case-control studies revealed no differences in overall reoperation rates between transplant recipients and controls. However, pelvic organ transplant recipients undergoing three-piece prosthesis implantation showed higher complications rates related to reservoir issues. Despite limited evidence, case-control studies demonstrated a generally low/moderate risk of bias within each specific domain, although overall bias was moderate/severe. As a result, clinicians may mitigate concerns regarding penile prosthesis implantation in solid organ transplant recipients.","PeriodicalId":14068,"journal":{"name":"International Journal of Impotence Research","volume":"37 1","pages":"18-26"},"PeriodicalIF":2.8,"publicationDate":"2024-07-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141723555","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Comment on: “Use of thermographic imaging for the evaluation of erectile dysfunction and Peyronie’s disease”","authors":"Raevti Bole","doi":"10.1038/s41443-024-00952-0","DOIUrl":"10.1038/s41443-024-00952-0","url":null,"abstract":"","PeriodicalId":14068,"journal":{"name":"International Journal of Impotence Research","volume":"36 7","pages":"799-799"},"PeriodicalIF":2.8,"publicationDate":"2024-07-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.nature.com/articles/s41443-024-00952-0.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141723554","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}