International Journal of Impotence Research最新文献

{"title":"Response to Comment: Testosterone deficiency in men with end-stage renal disease and kidney transplantation: a narrative review.","authors":"Charles Rinehart, Kimberly Waggener, Nicholas A Deebel, Ryan Terlecki","doi":"10.1038/s41443-025-01097-4","DOIUrl":"https://doi.org/10.1038/s41443-025-01097-4","url":null,"abstract":"","PeriodicalId":14068,"journal":{"name":"International Journal of Impotence Research","volume":" ","pages":""},"PeriodicalIF":2.8,"publicationDate":"2025-06-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144234026","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Contemporary approaches and treatment perspectives for chronic scrotal content pain: insights from a national practice patterns survey of reproductive urologists.","authors":"Anthony Bettencourt, Bryan D Naelitz, Leila Momtazi-Mar, Amelia Khoei, Joseph Borrell, Jaxon R Jeffery, Thiago P Furtado, Catherine S Nam, Nahid Punjani, Scott D Lundy, Sriram V Eleswarapu","doi":"10.1038/s41443-025-01101-x","DOIUrl":"https://doi.org/10.1038/s41443-025-01101-x","url":null,"abstract":"<p><p>A 25-item electronic survey was circulated to reproductive urologists from around the US to evaluate current national diagnostic and therapeutic practices for the management of chronic scrotal content pain (CSCP). Questions addressed physician demographics, referral patterns, diagnostic protocols, treatment approaches, and outcome perceptions. Forty-one of 183 (22.4%) invited participants completed the survey. Among ten conservative treatment options, reassurance (41.5%) and NSAIDs (31.7%) were most frequently ranked first, while opioid medications were the least preferred, with 56.1% of respondents ranking them last of the ten options. Microsurgical denervation of the spermatic cord was the most commonly utilized surgical procedure overall (95.1%) and the first choice for post-vasectomy pain syndrome (PVPS) in 63.0% of respondents. Vasectomy reversal was the surgery of choice for PVPS in only 22.0% of respondents. Respondents perceived higher complete symptom resolution (median: 75% vs. 25%) and lower failure rates (median: 10% vs. 20%) in patients who had surgery versus those who had only conservative measures. Only 7.3% of participants reported using validated assessment tools such as the Chronic Orchialgia Symptom Index. These results demonstrate that wide variability persists in CSCP management among reproductive urologists, though there is consensus that surgery has a higher success rate as compared to conservative management.</p>","PeriodicalId":14068,"journal":{"name":"International Journal of Impotence Research","volume":" ","pages":""},"PeriodicalIF":2.8,"publicationDate":"2025-06-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144225402","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Comment on: Hard-flaccid syndrome: a report of two cases.","authors":"Elena Colonnello, Emmanuele A Jannini","doi":"10.1038/s41443-025-01093-8","DOIUrl":"10.1038/s41443-025-01093-8","url":null,"abstract":"","PeriodicalId":14068,"journal":{"name":"International Journal of Impotence Research","volume":" ","pages":""},"PeriodicalIF":2.8,"publicationDate":"2025-06-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144215758","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Evaluating AI chatbots in penis enhancement information: a comparative analysis of readability, reliability and quality","authors":"Mehmet Vehbi Kayra,&nbsp;Hakan Anil,&nbsp;Ilturk Ozdogan,&nbsp;Suhail Mohamed Amin Baradia,&nbsp;Serdar Toksoz","doi":"10.1038/s41443-025-01098-3","DOIUrl":"10.1038/s41443-025-01098-3","url":null,"abstract":"This study aims to evaluate and compare the performance of artificial intelligence chatbots by assessing the reliability and quality of the information they provide regarding penis enhancement (PE). Search trends for keywords related to PE were determined using Google Trends ( https://trends.google.com ) and Semrush ( https://www.semrush.com ). Data covering a ten-year period was analyzed, taking into account regional trends and changes in search volume. Based on these trends, 25 questions were selected and categorized into three groups: general information (GI), surgical treatment (ST) and myths/misconceptions (MM). These questions were posed to three advanced chatbots: ChatGPT-4, Gemini Pro and Llama 3.1. Responses from each model were analyzed for readability using the Flesch-Kincaid Grade Level (FKGL) and Flesch Reading Ease Score (FRES), while the quality of the responses was evaluated using the Ensuring Quality Information for Patients (EQIP) tool and the Modified DISCERN Score. All chatbot responses exhibited difficulty in readability and understanding according to FKGL and FRES, with no statistically significant differences among them (FKGL: p = 0.167; FRES: p = 0.366). Llama achieved the highest median Modified DISCERN score (4 [IQR:1]), significantly outperforming ChatGPT (3 [IQR:0]) and Gemini (3 [IQR:2]) (p &lt; 0.001). Pairwise comparisons showed no significant difference between ChatGPT and Gemini (p = 0.070), but Llama was superior to both (p &lt; 0.001). In EQIP scores, Llama also scored highest (73.8 ± 2.2), significantly surpassing ChatGPT (68.7 ± 2.1) and Gemini (54.2 ± 1.3) (p &lt; 0.001). Across categories, Llama consistently achieved higher EQIP scores (GI:71.1 ± 1.6; ST: 73.6 ± 4.1; MM: 76.3 ± 2.1) and Modified DISCERN scores (GI:4 [IQR:0]; ST:4 [IQR:1]; MM:3 [IQR:1]) compared to ChatGPT (EQIP: GI:68.4 ± 1.1; ST: 65.7 ± 2.2; MM:71.1 ± 1.7; Modified DISCERN: GI:3 [IQR:1]; ST:3 [IQR:1]; MM:3 [IQR:0]) and Gemini (EQIP: GI:55.2 ± 1.4; ST:55.2 ± 1.6; MM:2.6 ± 2.5; Modified DISCERN: GI:1 [IQR:2]; ST:1 [IQR:2]; MM:3 [IQR:0]) (p &lt; 0.001). This study highlights Llama’s superior reliability in providing PE-related health information, though all chatbots struggled with readability.","PeriodicalId":14068,"journal":{"name":"International Journal of Impotence Research","volume":"37 7","pages":"558-563"},"PeriodicalIF":2.5,"publicationDate":"2025-06-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12283392/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144215759","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Setting the mood: improving patient satisfaction and clinic efficiency during penile duplex doppler ultrasound assessment.","authors":"Elise R Tentis, Kate E Nelson, Stephen M Carlson, Sevann Helo, Tobias S Kohler, Matthew J Ziegelmann","doi":"10.1038/s41443-025-01099-2","DOIUrl":"https://doi.org/10.1038/s41443-025-01099-2","url":null,"abstract":"<p><p>We sought to identify specific testing conditions that may negatively impact patient experience with Penile duplex Doppler ultrasound (PDDU). We developed a survey designed to assess perception with several predetermined clinical-environment factors. Patients completed the voluntary written-survey at the time of PDDU between January 2022 and June 2024. 37.4% of patients reported at least one of the following negatively impacted their experience: bright lights, hallway noises, room temperature, and frequent staff assessments. Preference regarding clinician gender and type (physician versus advanced practice provider) was also assessed. When assessed prior to starting the consultation, we found that 57.6% reported no provider preference, while 40.6% preferred consultation with physicians. 72.6% reported no provider gender preference, while 25.2% preferred males. In contrast, when assessed at the completion of the consultation, 84.4 and 85.7% reported no preference regarding provider type or gender, respectively. Based on interim analysis of survey response data, a call-button was implemented for patients to alert staff when adequate erection rigidity was achieved during testing. The mean time to response decreased significantly from 15.6 min ±4.2 to 11.2 min ±4.2 (p < 0.001). Further work is needed to validate and identify additional modifiable factors that can be improved upon to enhance patient experience.</p>","PeriodicalId":14068,"journal":{"name":"International Journal of Impotence Research","volume":" ","pages":""},"PeriodicalIF":2.8,"publicationDate":"2025-05-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144191783","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"The role of vacuum erection device and penile traction therapy in the patients after radical prostatectomy: a narrative review.","authors":"Tung Shu, Danqing Ren, Run Wang","doi":"10.1038/s41443-025-01092-9","DOIUrl":"https://doi.org/10.1038/s41443-025-01092-9","url":null,"abstract":"<p><p>Radical prostatectomy (RP) is a common treatment for localized prostate cancer, which unfortunately often results in sexual dysfunction, including, but not limited to erectile dysfunction (ED), penile atrophy and penile fibrosis. Various therapies have been used to manage these side effects associated with RP, including vacuum erection devices (VEDs) and penile traction therapy (PTT). This review focuses on the mechanisms, efficacy, and clinical applications of VED and PTT in post-RP patients. VED, a well-established, non-invasive modality, enhances penile blood flow, preserves tissue integrity, and facilitates early engagement in sexual activity. Although VED has been shown to help maintain penile length and improve sexual function, its effectiveness in accelerating spontaneous erectile function recovery remains uncertain. PTT, originally developed for Peyronie's disease, has recently been explored for post-RP patients. Preliminary studies suggest its potential in mitigating penile shortening and supporting functional recovery, though long-term efficacy data remain limited. Both therapies face challenges, including lack of standardized protocols, adherence issues, and encouraging, but limited evidence on their combined use with pharmacological interventions. Additionally, factors such as patient education, treatment accessibility, and psychological support play critical roles in therapy adherence and overall success. Further research is needed to optimize treatment protocols, improve patient compliance, and establish the role of VED and PTT in comprehensive post-RP care through large-scale, well-designed clinical trials.</p>","PeriodicalId":14068,"journal":{"name":"International Journal of Impotence Research","volume":" ","pages":""},"PeriodicalIF":2.8,"publicationDate":"2025-05-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144179999","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Penile cancer treatment and sexuality: a narrative review","authors":"Camille Roumieux,&nbsp;Kaat Vandermaesen,&nbsp;Eline Dancet,&nbsp;Maarten Albersen","doi":"10.1038/s41443-025-01095-6","DOIUrl":"10.1038/s41443-025-01095-6","url":null,"abstract":"Penile squamous cell carcinoma is a rare malignancy that poses a significant concern to those affected due to its aggressive nature and profound impact on patients’ quality of life. This review examines the evidence on the impact of penile cancer and its various treatments on the sexual health of patients. Men’s post-surgical sexual functioning has mainly been assessed with the International Index of Erectile Functioning. Some studies asked men to report retrospectively on pre-surgical sexual&nbsp;functioning or compared surgical techniques with non-randomized samples. Studies on patient’s perspectives on sexual sensations and appearance are emerging, &nbsp;however reliable assessments of sexual wellbeing are missing. Penile cancer significantly impacts patients’ sexual activity, sexual function, sexual sensations, cosmesis and sexual wellbeing. Considerable proportions of patients resume sexual activity following treatments, including organ-sparing procedures, partial or total penectomy, and adjuvant therapies. While organ-sparing surgeries can largely preserve sexual functioning, more invasive treatments like partial or total penectomy result in greater declines, with the impact on sexual wellbeing remaining underexplored. Rigorous prospective studies assessing valid and reliable patient reported outcome measures for sexual wellbeing besides sexual functioning are needed in order to fully&nbsp;understand and address the impact of penile cancer treatment on sexual health.","PeriodicalId":14068,"journal":{"name":"International Journal of Impotence Research","volume":"37 9","pages":"699-710"},"PeriodicalIF":2.5,"publicationDate":"2025-05-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144150403","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Impact of sleep quality and chronotype on self-reported erectile function in young adults presenting with erectile complaints: a prospective observational study.","authors":"Ali Nebioğlu, Mert Başaranoğlu, Selahittin Çayan","doi":"10.1038/s41443-025-01089-4","DOIUrl":"https://doi.org/10.1038/s41443-025-01089-4","url":null,"abstract":"<p><p>Erectile complaints are prevalent among young adults, with various factors potentially affecting sexual function and quality of life. This study investigates the impact of sleep quality and chronotype on erectile function in young adults who present with self-reported erectile difficulties. In this prospective study, 249 men with ED were included, assessed from January 2023 to July 2024. Sociodemographic and clinical data were collected for all participants, including age, body mass index (BMI), comorbid diseases, and hormonal parameters. All patients completed the following questionnaires: International Index of Erectile Function (IIEF-5), Pittsburgh Sleep Quality Index (PSQI), Morningness-Eveningness Questionnaire (MEQ), Depression Anxiety Stress Scales-42 (DASS-42), and General Health Questionnaire-28 (GHQ-28). Statistical analyses, including Spearman's correlation and Kruskal-Wallis tests, evaluated the relationships between sleep quality, chronotype, and ED. The average age was 31.03 ± 8.06 years. Significant correlations were found: Poor sleep quality was linked to lower erectile function (r = -0.379, p < 0.001), while morning chronotype correlated with better erectile function (r = 0.424, p < 0.001). Regression analysis confirmed these as significant predictors of ED (R² = 0.200, p < 0.001). Sleep quality and chronotype are crucial factors in ED management, suggesting targeted interventions could be beneficial.</p>","PeriodicalId":14068,"journal":{"name":"International Journal of Impotence Research","volume":" ","pages":""},"PeriodicalIF":2.8,"publicationDate":"2025-05-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144119465","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Global prevalence of erectile dysfunction in 2025: a call for updated epidemiological data.","authors":"Gang Chen","doi":"10.1038/s41443-025-01094-7","DOIUrl":"https://doi.org/10.1038/s41443-025-01094-7","url":null,"abstract":"","PeriodicalId":14068,"journal":{"name":"International Journal of Impotence Research","volume":" ","pages":""},"PeriodicalIF":2.8,"publicationDate":"2025-05-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144119458","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"“Rare sexual disorders”: shedding light on the unspoken spectrum of male sexual health","authors":"Murat Gül","doi":"10.1038/s41443-025-01090-x","DOIUrl":"10.1038/s41443-025-01090-x","url":null,"abstract":"","PeriodicalId":14068,"journal":{"name":"International Journal of Impotence Research","volume":"37 6","pages":"413-413"},"PeriodicalIF":2.5,"publicationDate":"2025-05-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.nature.comhttps://www.nature.com/articles/s41443-025-01090-x.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144093811","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}