Liaquat National Journal of Primary Care最新文献_第3页

Liaquat National Journal of Primary Care Pub Date : 1900-01-01 DOI: 10.37184/lnjpc.2707-3521.4.29

{"title":"Monkeypox: A Global Challenge","authors":"","doi":"10.37184/lnjpc.2707-3521.4.29","DOIUrl":"https://doi.org/10.37184/lnjpc.2707-3521.4.29","url":null,"abstract":"Monkeypox has emerged as the most significant human pathogen in recent times and is a rapidly growing threat to public health globally. Monkeypox virus is an orthopoxvirus, that belongs to the Poxviridae family. The smallpox virus also belongs to this family. Monkeypox virus, endemic to Central and West Africa can infect various animal species but can also transmit to humans. Monkeypox viruses circulate among wild animals and usually spread to people when they eat or have other close contacts with infected animals. Getting bitten or scratched by the infected animal, direct contact with its bodily fluids, blood, blisters or scabs; indirect contact with lesion material, e.g. contaminated bedding, linens and even eating the undercooked animal infected with monkeypox, could result in transmission. Among humans, Monkeypox is contracted through close physical contact, and contact with contaminated materials. Monkeypox presents with fever, headaches, myalgia, and enlarged lymph nodes. This is followed by a rash that starts from mouth to face and spreads to the trunk and arms. The illness is usually mild and patients fully recover within four weeks. Nucleic acid testing (NAT) is the primary diagnostic tool for detection. Polymerase chain reaction (PCR) is the preferred method for NAT. Treatment is mainly supportive and is directed to alleviate symptoms, prevent long-term sequelae and mitigate disease spread. Patients require isolation and symptomatic care. The smallpox vaccine, antiviral agents and vaccinia immunoglobulin (VIG) have been used in earlier outbreaks but sufficient evidence to recommend their use is still lacking.","PeriodicalId":140679,"journal":{"name":"Liaquat National Journal of Primary Care","volume":"86 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"1900-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"134122337","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 1

Hypercalciuria: Common but Under-diagnosed Cause of Hematuria 高钙尿:常见但诊断不足的血尿原因

Liaquat National Journal of Primary Care Pub Date : 1900-01-01 DOI: 10.37184/lnjpc.2707-3521.4.25

引用次数: 0

The Constant Threat of Emerging Viral Diseases 新出现的病毒性疾病的持续威胁

Liaquat National Journal of Primary Care Pub Date : 1900-01-01 DOI: 10.37184/lnjpc.2707-3521.1.18

引用次数: 1

Defecation Syncope; Digging Deep: A Case Report 排便晕厥;深挖:一个案例报告

Liaquat National Journal of Primary Care Pub Date : 1900-01-01 DOI: 10.37184/lnjpc.2707-3521.5.16

引用次数: 0

Spinal Surgery- Use of Dexmedetomidine for Myasthenia Grvis - A Case Report 脊柱外科-右美托咪定治疗重症肌无力1例报告

Liaquat National Journal of Primary Care Pub Date : 1900-01-01 DOI: 10.37184/lnjpc.2707-3521.1.19

{"title":"Spinal Surgery- Use of Dexmedetomidine for Myasthenia Grvis - A Case Report","authors":"","doi":"10.37184/lnjpc.2707-3521.1.19","DOIUrl":"https://doi.org/10.37184/lnjpc.2707-3521.1.19","url":null,"abstract":"Myasthenia gravis (MG) is a chronic autoimmune disease in which autoantibodies destroy acetylcholine receptors at motor end plat of neuromuscular junction which prevent skeletal muscle depolarization and contraction, causes muscle weakness and tiredness upon exertion with a tendency to be subsided after taking some rest or after taking anticholinesterase medication. Symptoms of progression of MG include the involvement of upper and lower extremities and muscle weakness that leads to inability in doing basic motor functions. The diagnosis of myasthenia gravis includes sign and symptoms, clinical examination and laboratory investigation of serum autoantibody (AChR autoantibodies) implicated in the disease pathology. Surgical procedures under general anesthesia in a patient with MG could be very challenging for an anesthetist because of pathophysiological manifestations of the disease. We report a case of a patient undergoing 4 level spinal fixation with coexistent myasthenia gravis (according to Osserman II B), requiring general anesthesia for spinal surgery in prone position. Myasthenia gravis affects the neuromuscular junction that is why it has a great significance of interest for the anesthetist.","PeriodicalId":140679,"journal":{"name":"Liaquat National Journal of Primary Care","volume":"11 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"1900-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"133460611","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Acceptability of COVID-19 Vaccines among Patients on Maintenance Hemodialysis: An Assessment from a Healthcare Center in Karachi 维持性血液透析患者COVID-19疫苗的可接受性:来自卡拉奇一家医疗中心的评估

Liaquat National Journal of Primary Care Pub Date : 1900-01-01 DOI: 10.37184/lnjpc.2707-3521.4.20

{"title":"Acceptability of COVID-19 Vaccines among Patients on Maintenance Hemodialysis: An Assessment from a Healthcare Center in Karachi","authors":"","doi":"10.37184/lnjpc.2707-3521.4.20","DOIUrl":"https://doi.org/10.37184/lnjpc.2707-3521.4.20","url":null,"abstract":"Dialysis patients are among the high-risk group to contract COVID-19 necessitating vaccination to decrease mortality and morbidity. We aimed to evaluate the COVID-19 vaccination status of dialysis patients in our institute (NIKUD). Regular hemodialysis patients (n=38) from Sept’21 to Jan’22 were included after taking written consent. The majority (78%) of patients were fully vaccinated and none was partially vaccinated. Sinopharm (36.6%) was the most frequent vaccine received, followed by Moderna (26%). Among vaccinated patients' families, the complete vaccination rate was (68%) for the COVID-19 vaccine as compared (0%) for the complete vaccination of family members in the unvaccinated group. Non-belief in the vaccine (75%) along with no known case of COVID-19 disease to self or family (100%) were the most common possible reasons for not getting vaccinated. Perceived risk of COVID-19 to themselves as non-dangerous was a concerning belief in the majority (44%) (17) dialysis patients. Approximately 25% of patients did not receive any COVID-19 vaccine including inadequate vaccination among their families. Evidence-Based counseling and education are advised to alleviate any concerns regarding COVID-19 vaccines.","PeriodicalId":140679,"journal":{"name":"Liaquat National Journal of Primary Care","volume":"17 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"1900-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"127862613","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Ticagrelor Induced Diffuse Alveolar Hemorrhage - A Case Report 替格瑞洛诱发弥漫性肺泡出血1例

Liaquat National Journal of Primary Care Pub Date : 1900-01-01 DOI: 10.37184/lnjpc.2707-3521.4.22

引用次数: 1

An Assessment of the State of Misinformation Regarding Eye Diseases and Their Treatment in the General Public 公众对眼病及其治疗的误传状况评估

Liaquat National Journal of Primary Care Pub Date : 1900-01-01 DOI: 10.37184/lnjpc.2707-3521.4.28

{"title":"An Assessment of the State of Misinformation Regarding Eye Diseases and Their Treatment in the General Public","authors":"","doi":"10.37184/lnjpc.2707-3521.4.28","DOIUrl":"https://doi.org/10.37184/lnjpc.2707-3521.4.28","url":null,"abstract":"Background: The importance of eye health in the overall well-being of an individual continues to be a neglected topic. As a result, potentially harmful knowledge gaps prevail. Myths and misconceptions continue to spread in low and middle-income regions such as Karachi.\u0000Objective: To identify perceptions of eye diseases and their treatment in a local subset of the population as well as the extent of their knowledge of ophthalmological conditions based on their education level.\u0000Methodology: This is a cross-sectional study conducted in the Out-Patient Department of Ophthalmology (OPD) of Dow International Medical College (DIMC), Karachi, from January 2021 until August 2021. Informed consent was signed, and each subject was interviewed using a questionnaire regarding their understanding of eye diseases. The data collected was then entered into the pro forma which was analyzed using SPSS version 23.\u0000Results: A total of 390 subjects were selected from the OPD. Their age ranged from 18 to 79 years with a mean age of 36.4 ± 14.2 years. The participants of the study consisted of 182 (46.7%) males and 208 (53.3%) females. However, There was a general perspective that cataract is a condition that can be corrected by using eye drops (18.7%) and that fennel, almonds, and rock candy are beneficial for the eyes (63.3%). Among people of all educational standards, the highly educated significantly demonstrated correct knowledge regarding whether the use of Surma and kajal (p=0.030), and arq-e-gulab (p=0.002) are beneficial and the need for a soft diet after cataract surgery (p=0.030).\u0000Conclusion: Despite the cultural beliefs we observed, people generally exhibited a relatively reasonable level of knowledge in terms of safe eye care practice.","PeriodicalId":140679,"journal":{"name":"Liaquat National Journal of Primary Care","volume":"44 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"1900-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"117241776","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Myocarditis Post mRNA COVID-19 Vaccine- To Fear or Not to Fear? 心肌炎mRNA - COVID-19疫苗-害怕还是不害怕?

Liaquat National Journal of Primary Care Pub Date : 1900-01-01 DOI: 10.37184/lnjpc.2707-3521.3.18

Adeeba Ahmed, Anam Lodhi, M. Siddiqui

引用次数: 0

Clinical and etiological profile of Complicated Urinary Tract Infection in Children: A health facility-based cross-sectional study 儿童复杂性尿路感染的临床和病因学概况:一项基于卫生机构的横断面研究

Liaquat National Journal of Primary Care Pub Date : 1900-01-01 DOI: 10.37184/lnjpc.2707-3521.6.6

{"title":"Clinical and etiological profile of Complicated Urinary Tract Infection in Children: A health facility-based cross-sectional study","authors":"","doi":"10.37184/lnjpc.2707-3521.6.6","DOIUrl":"https://doi.org/10.37184/lnjpc.2707-3521.6.6","url":null,"abstract":"Background: Urinary tract infection (UTI) is known to be the most frequent bacterial infection in the paediatric population.\u0000\u0000Objective: To determine the clinical profile and etiology of complicated urinary tract infection (UTI) in children.\u0000\u0000Methods: This cross-sectional study was done at the Department of Nephrology and Neonatology, National Institute of Child Health, Karachi from 1st January 2022 to 30th June 2022. In 241 children of either gender, (male and female) aged up to 15 years having structural or functional anomalies of the kidney and urinary tract or recurrent infection due to underlying kidney or urinary tract abnormalities were enrolled. Demographic and clinical characteristics along with laboratory parameters and etiological agents of complicated UTI were noted. Ultrasonography examination and dimercaptosuccinic acid (DMSA) renal scan (where indicated) were performed.\u0000\u0000Results: Of 241 children, 179 (74.3%) were male. The mean age was 3.08±3.63 years. Capillary refill time was prolonged in 78 (32.4%) children. Fever/chills, nausea/vomiting, urinary urgency, and dehydration were the most frequently noted clinical presentations reported in 232 (96.2%), 109 (45.2%), 91 (37.8%), and 89 (36.9%) children respectively. Ultrasonography findings were evident of bilateral moderative hydronephrosis in 60 (24.9%) children. E. coli followed by Pseudomonas and Klebsiella species were the most commonly found etiological agents noted in 98 (40.7%), 50 (20.7%), and 40 (16.6%) children respectively.\u0000\u0000Conclusion: The majority of the children with complicated UTIs were male. Fever/chills, nausea/vomiting, urinary urgency, and dehydration were the most frequently noted clinical presentations. The most commonly observed ultrasonography findings were bilateral moderative hydronephrosis","PeriodicalId":140679,"journal":{"name":"Liaquat National Journal of Primary Care","volume":"100 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"1900-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"125973505","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0