Liaquat National Journal of Primary Care最新文献_第4页

Neurological and Urological Malformations in Infant of Diabetic Mother at Tertiary Care Hospital; a Single Center Experience 三级医院糖尿病母亲的婴儿神经及泌尿系统畸形单一中心体验

Liaquat National Journal of Primary Care Pub Date : 1900-01-01 DOI: 10.37184/lnjpc.2707-3521.5.18

{"title":"Neurological and Urological Malformations in Infant of Diabetic Mother at Tertiary Care Hospital; a Single Center Experience","authors":"","doi":"10.37184/lnjpc.2707-3521.5.18","DOIUrl":"https://doi.org/10.37184/lnjpc.2707-3521.5.18","url":null,"abstract":"Background: Congenital anomalies mostly affecting the central neurological, urological, circulatory, and skeletal systems occur in the infant of diabetic mothers. \u0000\u0000Objective: This study was conducted to evaluate the neurological and urological malformations in the infant of a diabetic mother presenting at the NICU and causality department of NICH Karachi Pakistan.\u0000\u0000Methods: It was a cross-sectional study conducted at NICH Karachi, from July 2022 to Oct 2022. Infants born to diabetic mothers were enrolled in the study and neurological and urological malformations were determined with the help of radiography which was performed by a pediatric radiologist who has had expertise in his field for more than 15 years.\u0000\u0000Results: A total of 126 infants of diabetic mothers were included in this study. The age range of infants was 0-28 days. 1.58% of infants had neurological malformation. One infant had spina bifida occulta and other had mylomeningocele. 5% of infants were found to have urological malformations. 4 (3.2%) had a malformation of multicystic dysplastic kidney, 1 (0.8%) had agenesis and 1 (0.8%) had enlarged kidney syndrome.\u0000\u0000Conclusion: The present study analyzed a lower frequency of neurological and urological problems among infants of diabetic mothers. However, the frequency is low but it causes a great burden with serious outcomes. Therefore, proper screening is recommended for diabetic mothers to detect these malformations.","PeriodicalId":140679,"journal":{"name":"Liaquat National Journal of Primary Care","volume":"30 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"1900-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"124690394","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Celiac Disease in Short Stature Pediatric Population Presenting to Endocrinology Clinics: A Cross-Sectional Study from a Tertiary Care Hospital in Karachi 向内分泌科就诊的矮小儿科人群的乳糜泻:卡拉奇一家三级保健医院的横断面研究

Liaquat National Journal of Primary Care Pub Date : 1900-01-01 DOI: 10.37184/lnjpc.2707-3521.5.3

{"title":"Celiac Disease in Short Stature Pediatric Population Presenting to Endocrinology Clinics: A Cross-Sectional Study from a Tertiary Care Hospital in Karachi","authors":"","doi":"10.37184/lnjpc.2707-3521.5.3","DOIUrl":"https://doi.org/10.37184/lnjpc.2707-3521.5.3","url":null,"abstract":"Background: Among many reasons, short stature is one of them for referring children to paediatric endocrinology. The most frequent extra-intestinal symptom of celiac disease is short stature (SS). A very high probability of celiac disease is reported among children with SS for non-endocrinological reasons.\u0000Objective: To ascertain the frequency of celiac diseases among short-stature children presenting in endocrinology clinics in a tertiary care hospital.\u0000Methods: This descriptive cross-sectional study was performed in pediatric endocrinology clinics at the National Institute of Child Health for a six-month duration from February 2022 to July 2022. All short-stature children of any gender and age from 2 to 12 years were included in the study. Short stature was defined as height for age < -2 standard deviation for the corresponding age and gender. Serological investigation including Immunoglobin A (IgA), anti-tissue-transglutaminase antibodies (TTG IgA) and TTG IgG test was done by ELISA (enzyme-linked immunosorbent assay) method for all of the patients recruited into the study.\u0000Results: A total of 149 children with short stature were studied. The mean age of children was 10.2 ± 3.1 years. The majority of patients were males 53.7%. Average height and height for age z-score were 104.8 ± 8.9 cm and -5.1 ± 1.9 respectively. Out of 149 children, only 6.7% had positive serology for celiac diseases. None of the patients' factors was significantly different among patients with and without celiac disease.\u0000Conclusion: The current investigation discovered that patients with low stature had a substantial frequency of celiac disease. It was discovered that none of the patients' demographics were linked to celiac disease. For prompt diagnosis and treatment of celiac disease, people with short height should undergo screening.","PeriodicalId":140679,"journal":{"name":"Liaquat National Journal of Primary Care","volume":"64 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"1900-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"130805813","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Peritonitis – Etiology and Treatment Options: A Systematic Review 腹膜炎-病因学和治疗方案:系统综述

Liaquat National Journal of Primary Care Pub Date : 1900-01-01 DOI: 10.37184/lnjpc.2707-3521.6.2

引用次数: 0

Rare Case Report: Serratia Liquefaciens and Enterococcus Species as a Cause of Otogenic Brain Abscess Secondary to Active Epithelial Chronic Suppurative Otitis Media (CSOM) in a 12-Year Old Male Patient with Hemiparesis 罕见病例报告:液化沙雷菌和肠球菌引起的耳源性脑脓肿继发于活动性上皮性慢性化脓性中耳炎(CSOM)的12岁男性偏瘫患者

Liaquat National Journal of Primary Care Pub Date : 1900-01-01 DOI: 10.37184/lnjpc.2707-3521.4.33

{"title":"Rare Case Report: Serratia Liquefaciens and Enterococcus Species as a Cause of Otogenic Brain Abscess Secondary to Active Epithelial Chronic Suppurative Otitis Media (CSOM) in a 12-Year Old Male Patient with Hemiparesis","authors":"","doi":"10.37184/lnjpc.2707-3521.4.33","DOIUrl":"https://doi.org/10.37184/lnjpc.2707-3521.4.33","url":null,"abstract":"Developing countries face the problem of Otogenic intracranial complications especially in paediatric population because of poor hygiene, malnutrition and low immunity. Active epithelial type Chronic Suppurative Otitis Media (CSOM) can be the cause of potentially fatal complications. One of these is otogenic brain abscess. Having an estimated annual incidence to be approximately 0.5 per 100,000 children, it is associated with high mortality. \u0000We describe a unique case of otogenic brain abscess secondary to Active epithelial CSOM being neglected for two years and finding an unexpected foreign body in the right ear canal in a 12-year-old boy. The consultation was sought when the headache became intense and hemiparesis appeared. Our case is unique regarding both the clinical presentation and the causative organism. The patient underwent craniotomy, with elective capsulotomy, drainage of abscess and placement of a ventriculoperitoneal shunt. This was followed by a modified radical mastoidectomy two weeks later and an uneventful recovery.","PeriodicalId":140679,"journal":{"name":"Liaquat National Journal of Primary Care","volume":"9 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"1900-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"125417603","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Bone Mineral Density in Children with Congenital Adrenal Hyperplasia 先天性肾上腺增生儿童的骨密度

Liaquat National Journal of Primary Care Pub Date : 1900-01-01 DOI: 10.37184/lnjpc.2707-3521.5.43

{"title":"Bone Mineral Density in Children with Congenital Adrenal Hyperplasia","authors":"","doi":"10.37184/lnjpc.2707-3521.5.43","DOIUrl":"https://doi.org/10.37184/lnjpc.2707-3521.5.43","url":null,"abstract":"Background: C Treatment in all forms of CAH includes lifelong replacement of steroids. Steroids have an impact on bone health in multiple ways and are known to cause osteoporosis when given in high doses or for a longer duration.\u0000\u0000Objective: To evaluate bone mineral density (BMD), using dual-energy X-ray absorptiometry (DEXA) scan in children with CAH taking long-term steroids presenting in the pediatric endocrinology ward of National Institute of Child Health, (NICH) Karachi, Pakistan.\u0000\u0000Materials and Methods: This cross-sectional study was performed at the Department of Pediatric Endocrinology, National Institute of Child Health, Karachi from October 2021 to July 2022. A total of 47 diagnosed cases of CAH taking steroids for more than 5 years were enrolled. Assessment of BMD was done using a DEXA scan. Lumbar spine BMD was done and Z-score was modified for height for age z-score. The dose of steroids and duration was calculated.\u0000\u0000Results: Out of 47 patients, low BMD was observed in 8 (17.02%) patients. Individuals with low BMD had significantly higher median duration, (p=0.017), dose (p=0.003), and median alkaline phosphate level (p=0.036),) but low median BMD value (p=0.009) and z score (p<0.001) than normal BMD individuals. Although median bone age (p=0.009) was appropriate for chronologic age in low BMD patients. A moderate negative significant correlation was observed between z score and age (rho=-0.319, p=0.029), z-score and duration of steroid treatment (rho=-0.364, p=0.012), z score and alkaline phosphate (rho=-0.466, p=0.001), z score and bone age (rho=-0.378, p=0.009).\u0000\u0000Conclusion: Low BMD was observed in 17% of children on the DEXA scan. Moreover, these individuals had significantly higher median average duration and dose of hydrocortisone.","PeriodicalId":140679,"journal":{"name":"Liaquat National Journal of Primary Care","volume":"25 1 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"1900-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"126651682","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Effect of Raised Cardiac Troponin Levels on Inpatient Mortality in Patients with Community Acquired Pneumonia 心肌肌钙蛋白水平升高对社区获得性肺炎住院患者死亡率的影响

Liaquat National Journal of Primary Care Pub Date : 1900-01-01 DOI: 10.37184/lnjpc.2707-3521.4.10

{"title":"Effect of Raised Cardiac Troponin Levels on Inpatient Mortality in Patients with Community Acquired Pneumonia","authors":"","doi":"10.37184/lnjpc.2707-3521.4.10","DOIUrl":"https://doi.org/10.37184/lnjpc.2707-3521.4.10","url":null,"abstract":"OBJECTIVE: To ascertain the frequency of raised cardiac troponin level and its association with in-hospital mortality among patients presenting with severe community-acquired pneumonia (CAP) at a public-sector tertiary care hospital in Karachi.\u0000METHODOLOGY: This prospective, observational study was performed at Jinnah Postgraduate Medical Center, Karachi throughout September 2020 till March 2021 with the approval of the hospital ethics committee. 146 patients who met the diagnostic measures were included. Serum cardiac troponin levels≥0.034 ng/mL were labeled as elevated. A detailed history of patients was taken upon their hospital admission to note down their demographic and clinical features.\u0000RESULT: A total of 146 patients were studied with the majority of age range 46-70 years (n=91, 62.3%). 95 (65.1%) had elevated troponin levels. Age was significantly different among patients with and without elevated troponin levels (p=0.038). 87 (59.6%) patients did not survive and 57 (65.5%) of them had elevated troponin levels. The risk of mortality was greater among patients having elevated troponin levels but it was not considered statistically (OR=1.05, 95% CI: 0.53 – 2.10).\u0000CONCLUSION: The study did not find evidence of a greater likelihood of mortality for patients having elevated troponin levels.","PeriodicalId":140679,"journal":{"name":"Liaquat National Journal of Primary Care","volume":"55 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"1900-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"114147902","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

COVID-19 Depression- A Black Hole You Can Escape from COVID-19抑郁症-一个你可以逃脱的黑洞

Liaquat National Journal of Primary Care Pub Date : 1900-01-01 DOI: 10.37184/lnjpc.2707-3521.2.9

引用次数: 0

Iliopsoas Abscess in a 24-Months-Old Child: Management in Absence of an Identifiable Organism 24个月大的婴儿髂腰肌脓肿:在没有可识别的有机体的情况下的处理

Liaquat National Journal of Primary Care Pub Date : 1900-01-01 DOI: 10.37184/lnjpc.2707-3521.1.11

引用次数: 0

Effect of Prone Positioning in Patients with Moderate COVID-19 Pneumonia Admitted to Ward at a Tertiary Care Hospital 俯卧位对三级医院住院的中度COVID-19肺炎患者的影响

Liaquat National Journal of Primary Care Pub Date : 1900-01-01 DOI: 10.37184/lnjpc.2707-3521.3.27

{"title":"Effect of Prone Positioning in Patients with Moderate COVID-19 Pneumonia Admitted to Ward at a Tertiary Care Hospital","authors":"","doi":"10.37184/lnjpc.2707-3521.3.27","DOIUrl":"https://doi.org/10.37184/lnjpc.2707-3521.3.27","url":null,"abstract":"COVID -19 pneumonia can progress to severe disease in 5% of patients requiring intensive care management, which can put an excessive burden on health care systems. Prone positioning has been shown to improve oxygenation and decrease lung injury in patients with COVID-19 pneumonia and can be used as an adjunctive treatment to delay intubation. The objective of this study is to assess the effect of prone positioning in patients admitted to the COVID ward, with Moderate COVID-19 Pneumonia. This experimental study was conducted at Liaquat National Hospital. A quasi-experimental study design was applied. Patients with hypoxemia SpO2 < 94% were assisted to prone and semi-prone for up to 2 hours at a time for multiple sessions. Parameters like SaO2, PaO2/FiO2, hours of proning and changes and X-rays were recorded daily and pre and post-intervention values were compared. Paired t-test and Wilcoxon sign test were used to compare continuous parameters. A two-tailed p-value less than 5% of the level of significance was defined as statistically significant. 20 patients fulfilling the inclusion criteria were enrolled. Median hours of prone positioning were 48.5. The median hospital stay was 7.5 days. At baseline, mean PaO2/FiO2 ratio was 342±91.87 and at the time of discharge, it was 412.30±105.97 which is a statistically significant improvement from baseline (p=0.040). 50% of patients showed improvement in X-rays. One patient was intubated and all the patients were discharged. The sample collected in the current showed that prone positioning is a safe and feasible approach to improve oxygenation in moderate-severe COVID-19 pneumonias. However, studies with a larger sample size are recommended to further verify the findings of this study.","PeriodicalId":140679,"journal":{"name":"Liaquat National Journal of Primary Care","volume":"1 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"1900-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"127719713","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Sexual Perversion Leads to Laparotomy 性变态导致剖腹手术

Liaquat National Journal of Primary Care Pub Date : 1900-01-01 DOI: 10.37184/lnjpc.2707-3521.3.7

引用次数: 0