Liaquat National Journal of Primary Care最新文献

{"title":"Impact of Communicable Diseases during Flood Disaster in Pakistan, What’s next?","authors":"","doi":"10.37184/lnjpc.2707-3521.5.6","DOIUrl":"https://doi.org/10.37184/lnjpc.2707-3521.5.6","url":null,"abstract":"","PeriodicalId":140679,"journal":{"name":"Liaquat National Journal of Primary Care","volume":"2 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"1900-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"129888320","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Electromagnetic Hypersensitivity- A Disease of the New Era?","authors":"","doi":"10.37184/lnjpc.2707-3521.1.12","DOIUrl":"https://doi.org/10.37184/lnjpc.2707-3521.1.12","url":null,"abstract":"","PeriodicalId":140679,"journal":{"name":"Liaquat National Journal of Primary Care","volume":"1 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"1900-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"130138730","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Correlation of Dyspepsia with the type of First Meal of the Day; Breakfast or Brunch: A Cross-Sectional Study from Karachi Pakistan","authors":"","doi":"10.37184/lnjpc.2707-3521.5.31","DOIUrl":"https://doi.org/10.37184/lnjpc.2707-3521.5.31","url":null,"abstract":"Background: Breakfast skipping is traditionally viewed as a bad habit. The customary choice for those who skip breakfast is brunch. Changes in gastrointestinal function are correlated with a range of dietary factors.\u0000\u0000Objective: To evaluate the correlation of the type of first meal of the day with dyspepsia among patients visiting gastroenterology clinics with dyspeptic symptoms.\u0000\u0000Methods: This cross-sectional study was conducted in the Department of Gastroenterology, Liaquat National Hospital from August 2021 to April 2022. Short-Form Leeds Dyspepsia Questionnaire was used to identify the presence of dyspepsia (SF-LDQ). Breakfast was defined as the meal consumed in the morning and any beverages or food taken in the morning before 11:00 a.m. regularly in a week. Data were analyzed using the statistical package SPSS version 21.\u0000\u0000Results: A total sample of 390 patients were analyzed in this study with median age and duration of symptoms 35 (IQR=26-42) years 12 (IQR=8-24) months respectively. The frequency of breakfast skipping was 15.6%. The frequency of dyspeptic symptoms including indigestion, heartburn, regurgitation, and nausea was significantly higher among patients taking brunch as the first meal of the day than those who were having breakfast regularly. The frequency of dyspepsia was 75.1%. On univariate and multivariable analysis, the practice of consuming breakfast regularly was found to be associated with a lower risk of dyspepsia than those who were consuming brunch as the first meal of the day.\u0000\u0000Conclusion: \u0000The current study analyzed that type of first meal was significantly associated with dyspepsia. The frequency of dyspeptic symptoms was significantly higher among patients taking brunch at least once a week than patients who were regularly consuming breakfast.","PeriodicalId":140679,"journal":{"name":"Liaquat National Journal of Primary Care","volume":"33 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"1900-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"122372505","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Social Media Use During COVID-19: Real and Fake News?","authors":"Maarij Malik, M. A. Qamar, Syed Shabbir Afzal, Sohaib Tousif, Farheen Malik, Khizr Asif Bhura, Khizer Shamim","doi":"10.37184/lnjpc.2707-3521.3.14","DOIUrl":"https://doi.org/10.37184/lnjpc.2707-3521.3.14","url":null,"abstract":"The outbreak of COVID-19 led the world into disarray as people were forced to isolate themselves. Being known to be social animals, humans developed a coping mechanism: Increased use of social media as a means to bridge the physical distance. This review article aims to assess the impact, both positive and negative, of increased social media usage on lives. The Pandemic made it clear that whilst social media is an important outlet for information, it is also the culprit since most of the websites spread false/fabricated information to increase their viewership. As a result, it amplified anxiety and depression in people’s lives. Tools to monitor social media information are a necessity to outweigh its drawbacks. This includes filtering misinformation, providing mental health support, and encouraging people to refrain from spreading dubious content that lacks strong evidence.","PeriodicalId":140679,"journal":{"name":"Liaquat National Journal of Primary Care","volume":"41 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"1900-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"132686248","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Health Risk associated by Traditional and Complementary Medicines (T&CM) with Special Reference to Herbal Medicines either used alone or Concomitant with Conventional Pharmaceuticals","authors":"","doi":"10.37184/lnjpc.2707-3521.5.20","DOIUrl":"https://doi.org/10.37184/lnjpc.2707-3521.5.20","url":null,"abstract":"Traditional and Complementary Medicines (T&CM) are an integral part of health care having deep cited roots in history for the treatment and prophylaction of various mental and physical diseases and to maintain health in good conditions. Although T&CM includes herbal medicines, acupuncture, yoga, and some other indigenous practices this review is mainly focusing on the safety issues associated with the use of herbal medicines (including herbs, herbal materials, herbal preparations, and finished herbal products) either used alone or combined with conventional pharmaceuticals. The trend of using T&CM is on the rise currently as these products are branded as completely safe and free from any kind of adverse effects. This misperception is wrong because a lot of intrinsic and extrinsic factors are responsible to affect the quality of these drugs resulting in severe health consequences. Misidentification of herbs, overdosing, adulteration, and the presence of environmental contaminants like pesticides, heavy metals, and microbial and fungal contaminants are some issues that account for the risks associated with herbal medicines. Another alarming aspect is the concurrent use of both herbal and conventional medicines resulting in interactions of natural phytochemicals with synthetic constituents of conventional medicines resulting in potentiating or antagonizing the pharmacological effects of drugs. The need for time to ensure the quality, safety, and efficacy of T&CM according to the standards of the World Health Organization to make rational use of herbal medicines safe and sound.","PeriodicalId":140679,"journal":{"name":"Liaquat National Journal of Primary Care","volume":"1 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"1900-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"131046956","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Evaluation of Cardiovascular Responses Using Cold Presser Test as a Possible Future Risk for Hypertension in Normotensive Healthy Young Subjects","authors":"","doi":"10.37184/lnjpc.2707-3521.2.12","DOIUrl":"https://doi.org/10.37184/lnjpc.2707-3521.2.12","url":null,"abstract":"Hypertension is a major public health challenge and an emerging factor for cardiovascular co-morbidities globally. Exaggerated cardiovascular response to stress has been possible evidence to be a future risk for the development of hypertension and cardiac disorders. This cross-sectional study was done to evaluate cardiovascular responses using a cold presser test as a possible future risk for hypertension in normotensive healthy young students. A total of 70 healthy medical students of first-year MBBS, of both genders with ages between 18-22 years were included in the study. About 68.6% of students were found to be normal and were included in the normal response group. They showed no significant increase in heart rate, systolic or diastolic blood pressure. The participants showing a rise of systolic BP ≥25 mmHg or diastolic BP ≥20 mmHg were included in the hyper-response group. The overall mean age group in both male and female students was 20±1.56 years. In conclusion, 31.4% of normotensive medical students showed exaggerated cardiovascular responses to cold pressor tests which can be a possible risk for hypertension in these young normotensive individuals. Early interventions in their lifestyle modification can prevent them from developing hypertension in the future.","PeriodicalId":140679,"journal":{"name":"Liaquat National Journal of Primary Care","volume":"90 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"1900-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"115054460","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Sensitivity Pattern of Salmonella Typhi from Blood Culture in Paediatric Population","authors":"S. Saleem, A. Parkash, Muniba Jalil, Farheen Mubashir","doi":"10.37184/lnjpc.2707-3521.3.24","DOIUrl":"https://doi.org/10.37184/lnjpc.2707-3521.3.24","url":null,"abstract":"Background: The bacterium Salmonella enterica serovar typhi causes typhoid fever which is a life-threatening systemic infection that mainly occurs in developing countries of the world and remains a major public health issue. Paratyphoid fever is caused by Salmonella enterica serovars Paratyphi A and B and (infrequently C). Appropriate and immediate antimicrobial therapy is required for the prevention of complications and mortality due to enteric fever. Therefore, this study is designed to investigate the current sensitivity pattern of Salmonella typhi so that appropriate antibiotics can be initiated on time.\u0000Objective: To determine the sensitivity pattern of Salmonella typhi in enteric fever among the pediatric population visiting a tertiary care hospital.\u0000Methods: This cross-sectional study was carried at the Department of Pediatrics in National Institute of Child Health Karachi from 13-12-2019 to 13-06-2020 after acquiring ethical approval from the hospital committee. There were 149 children aged 3-12 years of either gender diagnosed with enteric fever selected for this study. Patients' information was collected on pre-designed proforma. Blood of five milliliters quantity was drawn and sent to the pathology department within 12 hours of the admission. Salmonella typhi was identified by biochemical testing of the suspicious non-lactose fermenting colonies. Mueller Hinton Agar medium was used for testing antibiotic sensitivity. The sensitivity of the drug was interpreted as Sensitive, Intermediate and Resistant based on inhibition zone size. \u0000Results: The average age of the children was 5.56±2.39 years. Sensitivity for meropenem, azithromycin was 100% and 93.3% respectively while the sensitivity of ciprofloxacin was 53.7%. Ampicillin, Co-trimoxazole, Chloramphenicol and Ceftriaxone were more than 80% resistant. \u0000Conclusion: Our study confirms the sensitivity for meropenem, azithromycin, ciprofloxacin. Ampicillin, Co-trimoxazole, Chloramphenicol and Ceftriaxone showed higher resistance. This study emphasizes the need for continuous evaluation and judicious use of antimicrobials, considering the ever-changing antibiogram.","PeriodicalId":140679,"journal":{"name":"Liaquat National Journal of Primary Care","volume":"33 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"1900-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"115418761","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Comparative Study of 3 Different Brands of Glimperide","authors":"","doi":"10.37184/lnjpc.2707-3521.2.6","DOIUrl":"https://doi.org/10.37184/lnjpc.2707-3521.2.6","url":null,"abstract":"Glimepiride is an antidiabetic agent used for lowering blood glucose levels. It induces the activity of peroxisome proliferator-activated receptor-gamma (PPAR gamma). It lowers blood glucose levels by binding to ATP-sensitive potassium channel receptors on the surface of pancreatic cells. The purpose of this study was to perform a comparative analysis of different physicochemical parameters (weight variation, hardness, thickness, friability, disintegration time, and dissolution time) of 3 different commercially available brands of glimepiride in the market. Statistical analysis revealed minor variations in the results. It was found that GETRYL showed the highest % dissolution among all the 3 brands whereas AMARYL took the least time to disintegrate. According to the results of the friability test, Diabold shows the highest stability in the friabilator. However, all 3 brands complied with the official pharmacopoeial limits. The quality of the drug largely influences its therapeutic activity. Hence, owing to the similar physicochemical profile, all the 3 brands can be interchangeably used.","PeriodicalId":140679,"journal":{"name":"Liaquat National Journal of Primary Care","volume":"663 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"1900-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"115123396","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Association of Thyroid Dysfunction with Unexplained Infertility in Women of Karachi Pakistan","authors":"","doi":"10.37184/lnjpc.2707-3521.5.26","DOIUrl":"https://doi.org/10.37184/lnjpc.2707-3521.5.26","url":null,"abstract":"Background: Thyroid autoimmunity and thyroid dysfunction is predominant in women of procreative age and has been linked with hostile fertility.\u0000\u0000Objective: To evaluate the association of thyroid dysfunction with unexplained infertility (UI).\u0000\u0000Material and Methods: A case-control study was performed by the department of Physiology Basic Medical Sciences Institute in collaboration with Jinnah Postgraduate Medical Centre, Karachi from May 2018 to June 2019. A sample size of 88 subjects; Group A (44 healthy fertile controls) and Group B (44 UI women) was calculated. Study variables included height, weight, body mass index, serum Triiodothyronine (T3), Thyroxine (T4), Thyroid-stimulating Hormone (TSH), Thyroid Binding Globulin (TBG), and Anti-thyroid peroxidase antibody (Anti -TPO). \u0000\u0000Results: UI females had high TSH concentration without any disturbance in T3 and T4 in comparison with controls, 40% of women with UI had TSH levels higher than 2.5 mIU/L as compared to 4% in controls. The mean TSH was 2.47±1.97mIU/L in UI females as compared to 1.10±2.14 mIU/L in controls. Both logistic regression models adjusted for age and body mass index showed that fertile controls were significantly less likely to be found with higher TSH (aOR=0.71, 95% CI: 0.52-0.98, p=0.040) and TBG (aOR=088, 95% CI: 0.81-0.95, p=0.002) as compared to females with UI.\u0000\u0000Conclusion: Minimal deviation of TSH (increased), raised anti-thyroid antibodies with slightly low T3 and T4 levels was observed in UI females. Mild variations in TSH within the normal range may contribute to some cases of UI therefore a direct need for thyroid profile assessment in all infertile females is recommended.","PeriodicalId":140679,"journal":{"name":"Liaquat National Journal of Primary Care","volume":"27 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"1900-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"121344131","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Trending in: Digitizing pathology with the emerging role of artificial intelligence (AI)","authors":"","doi":"10.37184/lnjpc.2707-3521.5.24","DOIUrl":"https://doi.org/10.37184/lnjpc.2707-3521.5.24","url":null,"abstract":"","PeriodicalId":140679,"journal":{"name":"Liaquat National Journal of Primary Care","volume":"70 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"1900-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"116243480","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}