Myocarditis Post mRNA COVID-19 Vaccine- To Fear or Not to Fear?

Abstract

Myocarditis is inflammation of the heart’s muscular layer [1], which presents with symptoms ranging from chest pain to arrhythmias, even shock. Julia et al. reported 1226 cases of post-vaccine myocarditis in which males aged 16 years or above were most vulnerable and developed symptoms following the second dose of the mRNA vaccine [1]. The mechanism of pathogenesis, however, is not elucidated. A hypothesis suggests a higher antibody response to the vaccine while another attributes it to a cytokine storm caused by some antiidiotype cross-reactive antibody in the myocardium [2].