International Journal of Infectious Diseases最新文献

{"title":"Corrigendum to “Prevalence of human T-lymphotropic virus type 1 infection among blood donors in mainland China: A meta-analysis” [Int J Infect Dis. 2014 Aug: 25;94–9]","authors":"Xin Li, Yuanzhong Chen, Zhengjun Wu, Na Zhang","doi":"10.1016/j.ijid.2025.107872","DOIUrl":"10.1016/j.ijid.2025.107872","url":null,"abstract":"","PeriodicalId":14006,"journal":{"name":"International Journal of Infectious Diseases","volume":"154 ","pages":"Article 107872"},"PeriodicalIF":4.8,"publicationDate":"2025-03-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143601620","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Population-level respiratory virus–virus interactions, Puerto Rico, 2013-2023","authors":"Zachary J. Madewell ,&nbsp;Joshua M. Wong ,&nbsp;Maile B. Thayer ,&nbsp;Vanessa Rivera-Amill ,&nbsp;Diego Sainz de la Peña ,&nbsp;Jorge Bertrán Pasarell ,&nbsp;Gabriela Paz-Bailey ,&nbsp;Laura E. Adams ,&nbsp;Yang Yang","doi":"10.1016/j.ijid.2025.107878","DOIUrl":"10.1016/j.ijid.2025.107878","url":null,"abstract":"<div><h3>Background</h3><div>Understanding virus–virus interactions is important for evaluating disease transmission and severity. Positive interactions suggest concurrent circulation, while negative interactions indicate reduced transmission of one virus when another is prevalent. This study examines interactions among seven respiratory viruses using a Bayesian approach that accounts for seasonality and long-term trends.</div></div><div><h3>Methods</h3><div>We analyzed data from 43,385 acute febrile illness cases in the Sentinel Enhanced Dengue Surveillance System in Puerto Rico (2013-2023). Viruses studied included influenza A (IAV), influenza B (IBV), respiratory syncytial virus (RSV), human parainfluenza viruses 1 and 3 (HPIV-1, HPIV-3), human adenovirus (HAdV), and human metapneumovirus (HMPV). Wavelet coherence analysis investigated synchronous or asynchronous viral co-variation, while a Bayesian hierarchical model estimated pairwise interactions.</div></div><div><h3>Results</h3><div>Among 43,385 participants, 26.0% tested positive for at least one virus, with IAV (9.5%), HAdV (4.1%), RSV (3.6%), and IBV (3.6%) being most frequent. Coinfections occurred in 0.5% of cases, often involving HAdV. Wavelet coherence identified significant synchronization among RSV/HMPV, HPIV-1/HMPV, and other virus pairs, with minimal coherence during the COVID-19 pandemic. Bayesian modeling suggested five virus–virus associations: four positive (RSV/HPIV-3, HMPV/HPIV-1, IBV/HAdV, IBV/HMPV) and one negative (IAV/HAdV). However, when restricting the analysis to the prepandemic period, fewer associations remained statistically credible.</div></div><div><h3>Conclusion</h3><div>Respiratory viruses in Puerto Rico demonstrate patterns of co-circulation that may reflect complex interactions, but these associations appear context-dependent. Findings highlight the need for continued surveillance to better understand virus–virus dynamics and their implications for public health interventions.</div></div>","PeriodicalId":14006,"journal":{"name":"International Journal of Infectious Diseases","volume":"154 ","pages":"Article 107878"},"PeriodicalIF":4.8,"publicationDate":"2025-03-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143624560","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Sero-epidemiology of measles immunoglobulin G antibodies among newborns from South-East Asia and sub-Saharan Africa: an observational, multicenter study","authors":"Carine Bokop ,&nbsp;Nisha Dhar ,&nbsp;Alane Izu ,&nbsp;Musa Mohammed Ali ,&nbsp;Godwin Akaba ,&nbsp;Hellen C. Barsosio ,&nbsp;James A Berkley ,&nbsp;Manisha Madhai Beck ,&nbsp;Tolossa E Chaka ,&nbsp;Clare L. Cutland ,&nbsp;Phurb Dorji ,&nbsp;Adama Mamby Keita ,&nbsp;Feleke Belachew Lema ,&nbsp;Nubwa Medugu ,&nbsp;Salim Mwarumba ,&nbsp;Stella Mwakio ,&nbsp;Stephen Obaro ,&nbsp;Eyinade K Olateju ,&nbsp;Rani Diana Sahni ,&nbsp;Samir K Saha ,&nbsp;Gaurav Kwatra","doi":"10.1016/j.ijid.2025.107882","DOIUrl":"10.1016/j.ijid.2025.107882","url":null,"abstract":"<div><h3>Objectives</h3><div>To investigate the transplacental acquisition of measles immunoglobulin (Ig)G in newborns at delivery in Bangladesh, Bhutan, India, Ethiopia, Mozambique, Kenya, Nigeria, Mali, and South Africa.</div></div><div><h3>Methods</h3><div>Archived cord serum, from a multicenter study on Group B <em>Streptococcus</em>, were tested for measles IgG using a commercial enzyme link immunosorbent assay (ELISA). We tested 323 randomly selected samples from each of the sites. Models using various measles antibody decay rates in infancy were explored.</div></div><div><h3>Results</h3><div>Overall, 2,907 cord serum samples were analyzed. At birth, 49.9% of newborns were measles IgG seronegative. Measles seronegativity ranged from 21.7% in Nigeria to 73.4% in Bhutan. The adjusted odds of seronegativity in infants of mothers born after measles vaccination implementation was 1.78 times that for infants born to unvaccinated mothers (adjusted odds ratio 1.78; 95% confidence interval 1.43-2.21; <em>P</em> &lt;0.001). Modeling measles-IgG kinetics predicted that 70.8%, 88.3%, and 100% of infants would be seronegative by 2, 4, and 6 months, respectively, without further exposure.</div></div><div><h3>Conclusions</h3><div>Our findings suggest low transplacental acquisition of measles IgG in newborns, which is likely to yield susceptibility to measles infection at a very young age. The currently recommended measles vaccine schedules in low- and middle-income countries (LMICs), with the first dose recommended from 9 months of age and onward, warrant reconsideration, including the need for earlier dosing schedules.</div></div>","PeriodicalId":14006,"journal":{"name":"International Journal of Infectious Diseases","volume":"154 ","pages":"Article 107882"},"PeriodicalIF":4.8,"publicationDate":"2025-03-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143624561","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Therapeutic response to an empirical praziquantel treatment in long-staying sub-Saharan African migrants with positive Schistosoma serology and chronic symptoms: A prospective cohort study in Spain","authors":"Sílvia Roure ,&nbsp;Xavier Vallès ,&nbsp;Olga Pérez-Quílez ,&nbsp;Israel López-Muñoz ,&nbsp;Lluís Valerio ,&nbsp;Laura Soldevila ,&nbsp;Anna Chamorro ,&nbsp;Elena Abad ,&nbsp;Alaa H.A. Hegazy ,&nbsp;Gema Fernández-Rivas ,&nbsp;Ester Gorriz ,&nbsp;Dolores Herena ,&nbsp;Elia Fernández-Pedregal ,&nbsp;Sergio España-Cueto ,&nbsp;Josep M. Llibre ,&nbsp;Mar Isnard ,&nbsp;Josep Maria Bonet ,&nbsp;Oriol Estrada ,&nbsp;Núria Prat ,&nbsp;Bonaventura Clotet","doi":"10.1016/j.ijid.2025.107873","DOIUrl":"10.1016/j.ijid.2025.107873","url":null,"abstract":"<div><h3>Objectives</h3><div>Sub-Saharan African migrants may be experiencing imported schistosomiasis, which can evolve into chronic schistosomiasis. Positive response to empiric treatment with praziquantel may indicate the presence of persistent infection.</div></div><div><h3>Methods</h3><div>We tested the response to praziquantel in a cohort of sub-Saharan African migrants with probable chronic schistosomiasis. The tests were administered at baseline and 6 and 12 months.</div></div><div><h3>Results</h3><div>Of the 187 eligible participants, 149 completed the follow-up. Of these, 119 (79.9%) were males and 65 (43.6%) were from Senegal. The median age was 43 years (interquartile ranges 35-51 years) and their duration of residence in Europe was 17 years (interquartile ranges 12-21 years). The most prevalent clinical symptom was chronic abdominal pain (N = 96, 64.4%), pelvic pain in males (N = 55, 46.6%), and dysmenorrhea (N = 21; 70.0%) in females. We observed a significant decrease (<em>P</em> &lt;0.001) in the number of signs and symptoms at 12 months, and 70.3% showed a total resolution of the symptoms and significant decreases in transaminase levels, eosinophilia, and abnormal glomerular filtration rates. The rates of clearance in positive enzyme-linked immunosorbent assay and immunochromatography tests were 54.7% and 24.3%.</div></div><div><h3>Conclusion</h3><div>The positive response to praziquantel suggests that chronic schistosomiasis is a prevalent condition among long-staying African migrants. These results need to be confirmed in randomized clinical trials.</div></div>","PeriodicalId":14006,"journal":{"name":"International Journal of Infectious Diseases","volume":"154 ","pages":"Article 107873"},"PeriodicalIF":4.8,"publicationDate":"2025-03-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143624562","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"HIV pre-exposure prophylaxis (PrEP) use among PrEP-eligible men who have sex with men: A systematic review and meta-analysis","authors":"Yuyan Zhao ,&nbsp;Huishan Li ,&nbsp;Yiting Huang ,&nbsp;Ziwei Zhou ,&nbsp;Zhuoqian He ,&nbsp;Bruce Agins ,&nbsp;Jason J. Ong ,&nbsp;Huachun Zou ,&nbsp;Yangyang She ,&nbsp;Hongbo Jiang","doi":"10.1016/j.ijid.2025.107874","DOIUrl":"10.1016/j.ijid.2025.107874","url":null,"abstract":"<div><h3>Objective</h3><div>Scaling up pre-exposure prophylaxis (PrEP) is critical to combating the AIDS epidemic, especially among PrEP-eligible men who have sex with men (MSM). This study summarizes the global proportion of PrEP-eligible MSM with PrEP use and highlights the contextual differences in eligibility criteria for PrEP across studies.</div></div><div><h3>Methods</h3><div>A literature search was conducted in four databases in July 2023. We determined the proportion of PrEP-eligible MSM with PrEP use and its 95% confidence interval (CI) using a random-effects meta-analysis.</div></div><div><h3>Results</h3><div>50 eligible studies involving 96,151 PrEP-eligible MSM were included. The overall pooled estimate of PrEP-eligible MSM with a history of PrEP use and current PrEP use was 19.3% (95% CI 13.9-26.2) and 21.8% (95% CI 17.6-26.7) with <em>β</em> regressions indicating an increasing trend. Subgroup analyses showed lower PrEP use among young MSM, and differences in PrEP use by research year, country income level, policy support and WHO region. Variations in eligibility criteria for PrEP were observed across studies.</div></div><div><h3>Conclusions</h3><div>An overall increase in PrEP use among PrEP-eligible MSM was observed, with differences in PrEP use mainly by age. Emphasis on identifying PrEP-eligible MSM, particularly young MSM and removing financial barriers for effective implementation. Global PrEP criteria should be more standardized and based on the latest science.</div></div>","PeriodicalId":14006,"journal":{"name":"International Journal of Infectious Diseases","volume":"154 ","pages":"Article 107874"},"PeriodicalIF":4.8,"publicationDate":"2025-03-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143624558","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Scaling-up symptom-agnostic, community-wide screening toward global tuberculosis elimination: opportunities, challenges, and lessons from history.","authors":"Hanif Esmail, Cecily Miller, Dennis Falzon, Gerard de Vries, Obioma Chijioke-Akaniro, Katherine C Horton, Mikashmi Kohli, Tejaswini Dharmapuri Vachaspathi, Luan N Q Vo, Syed M A Zaidi, S Bertel Squire, Anna K Coussens, Rein M G J Houben","doi":"10.1016/j.ijid.2025.107875","DOIUrl":"10.1016/j.ijid.2025.107875","url":null,"abstract":"<p><p>There has been little change in global tuberculosis (TB) incidence in the 21^st century. Although case notification has increased, millions of people with TB each year remain unreached. Recently there has been increased recognition that many people with undiagnosed, potentially infectious TB do not experience or report TB symptoms. Symptom-agnostic screening (e.g., by chest X-ray) can effectively identify such forms of TB. Although this activity is increasing globally and is beneficial to individuals screened, current levels fall far short of what is needed to impact transmission and population-level prevalence. A significant scale-up of symptom-agnostic screening across communities is required to improve treatment coverage and interrupt transmission. Although there are major political, financial, and health system challenges to undertaking such scale-up this is not without precedent. In the mid-20^th century, in many countries that now experience a low TB burden, population-level chest X-ray screening was successfully undertaken and contributed to the decline in TB. In this article, we explore the challenges and opportunities that face countries wanting to scale-up symptom-agnostic screening and reflect on important lessons from the past.</p>","PeriodicalId":14006,"journal":{"name":"International Journal of Infectious Diseases","volume":" ","pages":"107875"},"PeriodicalIF":4.8,"publicationDate":"2025-03-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143604980","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Host-directed therapy in diabetes and tuberculosis comorbidity toward global tuberculosis elimination.","authors":"Steven G Smith, Ruth Bowness, Jacqueline M Cliff","doi":"10.1016/j.ijid.2025.107877","DOIUrl":"10.1016/j.ijid.2025.107877","url":null,"abstract":"<p><p>Host-directed therapy could potentially revolutionize tuberculosis control as an adjunct to traditional antibiotics for the treatment of tuberculosis disease and as a strategy to prevent disease progression following Mycobacterium tuberculosis infection. The growing type 2 diabetes pandemic is hampering tuberculosis control worldwide, as people with diabetes have an increased risk of developing tuberculosis disease as well as worse treatment outcomes. Pulmonary tuberculosis is characterized by an inflammatory response that can cause alveolar tissue destruction and cavitation, and this inflammation is exacerbated in people with tuberculosis-diabetes comorbidity. Thus, the reduction of the inflammatory response is a key goal of host-directed therapy to dampen immunopathology, but it is vital that the inflammatory response is not suppressed too much, or the immune system will not be able to react to M. tuberculosis and mycobacterial replication will intensify. Furthermore, the type I interferon response and host cell metabolism are further dysregulated in tuberculosis-diabetes comorbidity, likely contributing to poor treatment outcomes. Achieving the right balance in terms of modulating the inflammatory and immune responses, both quantitatively and temporally, is more complex in tuberculosis-diabetes comorbidity, and this population should be included specifically in clinical trials of new regimens. In this regard, mathematical modeling has a key role in elucidating which biologic pathways should be targeted in different people. Host-directed therapy for people with tuberculosis-diabetes comorbidity will reduce immunopathology and post-tuberculosis lung disease, as well as boost microbiologic cure and treatment outcomes, and thus help in the fight toward global tuberculosis elimination.</p>","PeriodicalId":14006,"journal":{"name":"International Journal of Infectious Diseases","volume":" ","pages":"107877"},"PeriodicalIF":4.8,"publicationDate":"2025-03-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143604973","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Tuberculosis and HIV coinfection: Progress and challenges towards reducing incidence and mortality.","authors":"Bianca Sossen, Mmamapudi Kubjane, Graeme Meintjes","doi":"10.1016/j.ijid.2025.107876","DOIUrl":"10.1016/j.ijid.2025.107876","url":null,"abstract":"<p><p>HIV-associated tuberculosis (HIV-TB) is associated with disproportionate mortality: approximately 24% of the 660,000 individuals with TB and HIV died, compared to 11% of those without HIV dying from TB in 2023. HIV is a key driver of ongoing high TB incidence in many countries, particularly in the World Health Organization Africa region, and TB is the leading cause of hospitalization in people with HIV (PWH) globally. Significant developments have occurred recently concerning the prevention, screening, diagnosis, and management of HIV-TB. Antiretroviral therapy and novel regimens for TB preventive therapy are now known to decrease TB incidence and improve survival. The use of Xpert Ultra (Cepheid, USA) and urine Determine^TM TB LAM Antigen (Abbott, USA) as diagnostics are associated with improved survival for HIV-TB. However, there are ongoing gaps in our knowledge: regarding the natural history of TB disease in PWH; optimal approaches to diagnosis of TB and TB drug resistance including in non-sputum samples; and post-TB disease in PWH. We discuss recent progress, together with ongoing challenges towards reducing incidence, morbidity, and mortality. We highlight ongoing research that will advance our understanding and management of HIV-TB: including vaccine research, novel treatment strategies, and expanded options for the diagnosis of TB and drug resistance in PWH.</p>","PeriodicalId":14006,"journal":{"name":"International Journal of Infectious Diseases","volume":" ","pages":"107876"},"PeriodicalIF":4.8,"publicationDate":"2025-03-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143597024","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Variability of antimicrobial susceptibility of commensal Neisseria species supports its use as a marker of excessive antimicrobial consumption – reflections from the results of a four-country study","authors":"Izumo Kanesaka ,&nbsp;Claudio Foschi ,&nbsp;Antonella Marangoni ,&nbsp;Paul C Adamson ,&nbsp;Jeffrey Klausner ,&nbsp;Huan Vinh Dong ,&nbsp;Thibaut Vanbaelen ,&nbsp;Irith De Baetselier ,&nbsp;Tessa de Block ,&nbsp;Sheeba Santhini Manoharan-Basil ,&nbsp;Chris Kenyon","doi":"10.1016/j.ijid.2025.107870","DOIUrl":"10.1016/j.ijid.2025.107870","url":null,"abstract":"<div><div>This perspective explores the utility of commensal <em>Neisseria</em> species as an early warning sign of excessive antimicrobial consumption. Little is known as to how the prevalence and antimicrobial susceptibility of various commensal <em>Neisseria</em> species varies between populations around the world. We compared the prevalence and antimicrobial susceptibilities of oral commensal <em>Neisseria</em> species in the general population and cohorts of men who have sex with men (MSM) in four countries with available data – Belgium, Italy, Japan and Vietnam. In individuals where <em>Neisseria</em> spp. were detected, N<em>. subflava</em> was present in 70-100% of individuals in the different studies. The N<em>. subflava</em> azithromycin and ciprofloxacin minimum inhibitory concentrations (MICs) were higher in the MSM than in the general population. The MICs of all <em>Neisseria</em> spp. were very similar in the general populations of Belgium and Italy. For all <em>Neisseria</em> spp., azithromycin and ceftriaxone MICs were higher, whereas ciprofloxacin MICs were lower in Belgium and Italy than in Japan. The higher azithromycin and ciprofloxacin MICs observed in the cohorts of MSM compared to the general population and the higher ciprofloxacin MICs in Japan compared to Belgium and Italy are commensurate with the most commonly antimicrobial prescribed in these populations. Our results support using commensal <em>Neisseria</em> species as an early warning system of excessive antimicrobial consumption.</div></div>","PeriodicalId":14006,"journal":{"name":"International Journal of Infectious Diseases","volume":"154 ","pages":"Article 107870"},"PeriodicalIF":4.8,"publicationDate":"2025-03-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143585727","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Global containment policy duration and long-term epidemic progression: A target trial emulation using COVID-19 data from 2020 to 2022","authors":"Zhiyao Li ,&nbsp;Zhen Wang ,&nbsp;Xin Wang ,&nbsp;Senke Chen ,&nbsp;Wenxue Xiong ,&nbsp;Chaonan Fan ,&nbsp;Wenjuan Wang ,&nbsp;Meng Zheng ,&nbsp;Kunpeng Wu ,&nbsp;Qun He ,&nbsp;Wen Chen ,&nbsp;Li Ling","doi":"10.1016/j.ijid.2025.107871","DOIUrl":"10.1016/j.ijid.2025.107871","url":null,"abstract":"<div><h3>Objectives</h3><div>Global countries often apply containment policies (CPs) to combat infectious disease surges. Whether countries with longer cumulative duration of CPs are associated with slower long-term epidemic progression necessitates a thorough evaluation.</div></div><div><h3>Methods</h3><div>We collected CP and COVID-19 data of 185 territories during 2020-2022, with a total of 23 CPs. Using the target trial emulation and cloning-censoring-weighting approaches, we assessed the effectiveness of CPs with different cumulative durations in delaying countries from reaching the 1% and 10% cumulative infection incidence end points (i.e. 10,000 and 100,000 COVID-19 cases per million population, respectively) over a 3-year observation period.</div></div><div><h3>Results</h3><div>For reaching the 1% cumulative infection incidence, recommending closing workplaces and limiting gatherings to 10 people, each presented that a longer cumulative duration of those CPs is associated with a lower proportion of countries achieving this end point throughout 2020-2022. For reaching the 10% cumulative infection incidence, mandatory bans on public events and domestic movements, closing public transports, and screening and quarantining inbound tourists, each showed similar associations. Notably, long-lasting border bans upon high-risk regions are associated with a higher proportion of countries reaching the 10% cumulative infection incidence.</div></div><div><h3>Conclusions</h3><div>From the long-term perspective, we highlight CPs that warrant extending the duration to achieve slower epidemic progression. By contrast, our findings demonstrate the limited effectiveness of the ban on regions in slowing the long-term epidemic progression.</div></div>","PeriodicalId":14006,"journal":{"name":"International Journal of Infectious Diseases","volume":"154 ","pages":"Article 107871"},"PeriodicalIF":4.8,"publicationDate":"2025-03-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143585726","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}