International Journal of Endocrinology and Metabolism最新文献

{"title":"Clinical and Biochemical Characteristics and Treatment Outcomes of Ketosis-Prone Diabetes: The Remission Prone Diabetes.","authors":"Swaraj Shrikant Waddankeri,&nbsp;Meenakshi Swaraj Waddankeri,&nbsp;Basavraj Gurushantappa Mangshetty","doi":"10.5812/ijem.106799","DOIUrl":"https://doi.org/10.5812/ijem.106799","url":null,"abstract":"<p><strong>Background: </strong>Diabetic ketoacidosis (DKA) is one of the severe acute complications of diabetes. It has long been considered a key clinical characteristic of type 1 diabetes mellitus (T1DM) with severe and irreversible deficient insulin levels. Ketosis-prone diabetes (KPD) has pathophysiology close to T2DM but shows signs and symptoms associated with T1DM. In general, patients with ketosis-prone diabetes display elevated glucose and ketone levels; also, a higher hemoglobin A₁C than conventional T2DM.</p><p><strong>Objectives: </strong>The current research aimed to elucidate the clinical presentation and outline a management plan for KPD in the Indian population.</p><p><strong>Methods: </strong>The present case series is a descriptive, prospective, and observational case series on six unprovoked cases of KPD. They were managed using the standard protocol of DKA management.</p><p><strong>Results: </strong>The recruited cases followed a set pattern of very high insulin requirement at diagnosis. On follow-up, the insulin requirement progressively declined, and all of the cases were able to stop insulin therapy after a mean period of four weeks. None of the cases presented any organ damage at diagnosis. There was no recurrence of DKA during the two-year follow-up. All of the cases had normal liver and renal functions. Autoantibodies were negative in all of the cases.</p><p><strong>Conclusions: </strong>Ketosis-prone diabetes is the most under-recognized and under-diagnosed among all types of diabetes. Its recognition is of utmost importance as the approach of its treatment varies widely from that of the conventional type of diabetes. Proper follow-up, especially in unprovoked cases of DKA with obese phenotype, could help elucidate this rare entity of KPD where insulin can be stopped and maintain normoglycemia for a substantial period without insulin.</p>","PeriodicalId":13969,"journal":{"name":"International Journal of Endocrinology and Metabolism","volume":null,"pages":null},"PeriodicalIF":2.1,"publicationDate":"2021-03-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/09/69/ijem-19-2-106799.PMC8198612.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"39249532","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Comparing Oxidative Stress Status Among Iranian Males and Females with Malignant and Non-malignant Thyroid Nodules.","authors":"Bita Faam,&nbsp;Ata A Ghadiri,&nbsp;Mohammad Ali Ghaffari,&nbsp;Mehdi Totonchi,&nbsp;Layasadat Khorsandi","doi":"10.5812/ijem.105669","DOIUrl":"https://doi.org/10.5812/ijem.105669","url":null,"abstract":"<p><strong>Background: </strong>Oxidative stress is commonly accrued in thyroid tissue during hormone synthesis.</p><p><strong>Objectives: </strong>We aimed to examine oxidative stress in patients with thyroid cancer, benign thyroid nodules, and healthy individuals.</p><p><strong>Methods: </strong>In this study, 138 individuals were involved. Among the selected participants, 108 had thyroid nodules, including 30 papillary thyroid cancer (PTC), 30 follicular thyroid cancer (FTC), six anaplastic thyroid cancer (ATC), 12 medullary thyroid cancer (MTC), and 30 benign nodules. In addition, 30 individuals were selected as a healthy control group. The levels of total antioxidant capacity (TAC) and total oxidant status (TOS) of thyroid tissue were measured using the ELISA method, and the oxidative stress index (OSI) was calculated.</p><p><strong>Results: </strong>The TAC level was significantly lower in MTC and FTC subtypes than in controls. The TOS level was considerably higher in the MTC group than in the control and benign nodule groups. The TOS level was not changed in other groups. The OSI was considerably higher in MTC and FTC subtypes. The TAC and OSI in benign nodules were significantly lower and higher than those of controls, respectively. The OSI was higher in female patients than in males.</p><p><strong>Conclusions: </strong>The OSI can not be considered a diagnostic biomarker for benign nodules and MTC. The diverse oxidative stress status between genders may be related to the elevated cancer incidence in females.</p>","PeriodicalId":13969,"journal":{"name":"International Journal of Endocrinology and Metabolism","volume":null,"pages":null},"PeriodicalIF":2.1,"publicationDate":"2021-01-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/fc/50/ijem-19-1-105669.PMC8010567.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"25574087","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"A Pediatric Parathyroid Carcinoma: An Unusual Clinical Presentation and Mini-review.","authors":"Abbas Rahimi,&nbsp;Roghayeh Shahbazi,&nbsp;Pooneh Nikuei,&nbsp;Sanaz Soleimani,&nbsp;Azadeh Moradkhani,&nbsp;Ali Atashabparvar,&nbsp;Farnaz Khajehrahimi,&nbsp;Ghazal Zoghi,&nbsp;Masoumeh Kheirandish","doi":"10.5812/ijem.110234","DOIUrl":"https://doi.org/10.5812/ijem.110234","url":null,"abstract":"<p><strong>Introduction: </strong>Primary hyperparathyroidism (PHPT) is a rare condition in the pediatric population. Parathyroid carcinoma (PC) is a very uncommon cause of PHPT, accounting for < 1% of pediatric PHPT cases. It is challenging to distinguish between parathyroid adenoma (PA), the most common cause of PHPT, and PC. In this report, we described a young female who presented with a history of progressive limping and was finally diagnosed with PC.</p><p><strong>Case presentation: </strong>A 15-year-old girl presented with progressive limping and bone pain for 8 years. She was referred by an orthopedic surgeon because of elevated intact parathyroid hormone (iPTH) for further evaluation. Physical examination revealed a large, firm, and non-tender neck mass, left hip tenderness, and limited range of motion. The initial biochemistry tests showed a borderline high calcium level of 10.8 mg/dl, an elevated iPTH level of 2876 pg/mL, and a decreased phosphorus level of 2.4 mg/dL. The ^99mTechnetium (Tc) sestamibi scan displayed early intense activity in the right thyroid lobe persisting in the three-hour repeat scan, compatible with a parathyroid lesion. The patient underwent right-sided neck exploration and parathyroidectomy. Intraoperative and pathology findings confirmed the diagnosis of PC. Immunohistochemistry (IHC) staining revealed creatine kinase (CK) and CD31 in endothelial cells of the tumor. Ki67 staining was also positive in 2% - 3% of tumor cells. The whole exome sequencing (WES) study was negative for cell division cycle 73 (CDC73) and multiple endocrine neoplasia 1 (MEN1) genes.</p><p><strong>Conclusions: </strong>PC should be considered as a differential diagnosis of PHPT in the pediatric population, even in the presence of mild hypercalcemia.</p>","PeriodicalId":13969,"journal":{"name":"International Journal of Endocrinology and Metabolism","volume":null,"pages":null},"PeriodicalIF":2.1,"publicationDate":"2021-01-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/60/9d/ijem-19-1-110234.PMC8010565.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"25574091","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Familial-Related Risks for Congenital Hypothyroidism in Iranian Newborns: A Population-Based Case-Control Study.","authors":"Shahin Yarahmadi,&nbsp;Nasrin Azhang,&nbsp;Mahmood Salesi,&nbsp;Khaled Rahmani","doi":"10.5812/ijem.104889","DOIUrl":"https://doi.org/10.5812/ijem.104889","url":null,"abstract":"<p><strong>Background: </strong>Congenital hypothyroidism (CH), as one of the most common endocrine disorders, is a preventable cause of mental retardation.</p><p><strong>Objective: </strong>This study aimed to identify familial-related risk factors for CH in Iranian newborns.</p><p><strong>Methods: </strong>A population-based case-control study was performed on the National Registry System of patients with CH in Iran. In this study, 906 controls and 454 cases were studied for one year. Familial related factors were investigated using logistic regression models. Population attributable fraction (PAF) was also calculated for each significant risk factor.</p><p><strong>Results: </strong>Using multivariate analysis, an increased risk for CH was observed in patients with congenital anomalies (odds ratio (OR): 5.77, 95% confidence interval (CI): 2.37 - 14.01), history of mental retardation in family (OR:2.10, 95% CI: 1.15-3.83), mother's hypothyroidism during pregnancy (OR: 2.01, 95% CI: 1.33 - 3.03), intra-family marriage (OR:1.49, 95% CI: 1.18 - 1.89), gestational diabetes (OR: 1.69, 95% CI: 1.09 - 2.63), having a hypothyroid child in the family (OR: 2.48, 95% CI: 1.39 - 4.42), and twins or more (OR: 2.61, 95% CI: 1.31 - 5.21). The highest PAF among familial-related risk factors for CH is related to the intra-family marriage (14.9%).</p><p><strong>Conclusions: </strong>This study revealed that familial-related risk factors and consanguine marriages play an essential role in the high incidence of CH in Iran. About 15% of CH in Iran could be attributed to intra-family marriage alone.</p>","PeriodicalId":13969,"journal":{"name":"International Journal of Endocrinology and Metabolism","volume":null,"pages":null},"PeriodicalIF":2.1,"publicationDate":"2021-01-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/e6/17/ijem-19-1-104889.PMC8010566.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"25574086","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Effect of Correction of Hyperthyroidism with Anti-thyroid Drugs on the Glycated Hemoglobin in Non-diabetic Patients with Primary Hyperthyroidism.","authors":"Dasari Mani Deepthi,&nbsp;Suresh Vaikkakara,&nbsp;Avinash Patil,&nbsp;Sandeep Ganta,&nbsp;Alok Sachan,&nbsp;Katakam Raghavendra,&nbsp;Vinapamula S Kiranmayi,&nbsp;Amit Kumar Chowhan","doi":"10.5812/ijem.105751","DOIUrl":"https://doi.org/10.5812/ijem.105751","url":null,"abstract":"<p><strong>Background: </strong>Glycated hemoglobin (HbA1c) levels are dependent not only on the average blood glucose levels over the preceding 2 - 3 months but also on the turnover of erythrocytes. Hyperthyroidism is known to be associated with an increase in erythrocyte turnover that may falsely lower the HbA1c in relation to the level of glycemia.</p><p><strong>Objectives: </strong>To assess the impact of medical correction of hyperthyroidism on HbA1c, independent of changes in the fasting plasma glucose and 2-hour post-oral glucose tolerance test plasma glucose.</p><p><strong>Methods: </strong>Adult patients with overt hyperthyroidism (n = 36) were tested for their hemoglobin, reticulocyte percentage, HbA1c and fasting and post-oral glucose tolerance test (OGTT) 2-hour plasma glucose, both at baseline and following at least three months of near normalization of serum thyroxin on Carbimazole treatment.</p><p><strong>Results: </strong>Correction of hyperthyroidism in 36 patients was associated with an increase in the hemoglobin (P = 0.004) and a rise in HbA1c (P = 0.025), even though no significant change was observed in both the fasting (P = 0.28) and post OGTT two-hour plasma glucose (P = 0.54). Also, the proportion of patients with HbA1c ≥ 5.7% rose from 3/36 to 10/36; P = 0.016, while the proportion of patients with either abnormal fasting or abnormal post OGTT 2-hour plasma glucose or both did not show any significant change (P = 0.5). The sensitivity of HbA1c to diagnose prediabetes increased from 20% to 50% post- treatment.</p><p><strong>Conclusions: </strong>Glycated hemoglobin is falsely low in relation to glycemia in patients with untreated hyperthyroidism.</p>","PeriodicalId":13969,"journal":{"name":"International Journal of Endocrinology and Metabolism","volume":null,"pages":null},"PeriodicalIF":2.1,"publicationDate":"2021-01-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/f4/76/ijem-19-1-105751.PMC8010563.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"25574088","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"COVID-19-Related Weight Gain in School-Aged Children.","authors":"Mohammadreza Rezaeipour","doi":"10.5812/ijem.110634","DOIUrl":"https://doi.org/10.5812/ijem.110634","url":null,"abstract":"Dear Editor, This letter describes a proposed method to prevent children from gaining weight during not attending school due to COVID-19. The pandemic of Coronavirus Disease 2019 (COVID-19) is making considerable mortality and morbidity, putting pressure on health care systems, winding down the economy, and increasing school absenteeism. While lowering its immediate impact is a priority, I want to focus on a long-term impact on the health of children. By not attending school and staying at home, COVID-19 may lead to a stepped-up children’s obesity epidemic and increases obesity disorders. The COVID-19 pandemic has prevented students from attending school, forcing them to stay at home in many parts of Iran. The school system is not expected to return to normal this school year. Experiences gained in the Middle East countries such as Iran indicate that the observance of social distancing if canceled after a short time, must be periodically re-established its orders to control the prevalence of COVID-19 (1, 2). In summary, the COVID-19 pandemic in Iran is expected to intensify dramatically this year and increase school absenteeism, which will make worse the risk factors for weight gain related to summer vacations. Although a lot of literature is available about poor eating habits and body exercises in schools, according to research, children experience an increase in unhealthy weight not within the school year but generally in the summer months when they do not attend school (3-5). A study during school years has shown that the outbreak of overweight/obesity in students occurred only within the summer vacations (3). Research and follow-up studies show that an abnormal increase in weight is evident at school summer vacation, especially for some breeds, as well as children who were already extra weight (3, 5). It is worth noting that the data obtained indicate that the weight increased during the summer months remains throughout the school year and accumulates from summer to summer (5). Abnormal weight gain in childhood is a long-standing problem, as another study showed that childhood obesity is related to adulthood weight gain (6). For example, an abnormal increase in weight at the age of five was significantly linked to an increase in body mass index and fat mass in middle age (6). I argue that with raising out-of-school time, the pandemic of COVID-19 aggravates all risk factors for abnormal weight gain due to summer vacations (7). Not attending school, staying at home, and on-place shelter orders challenge children in the field of nutrition and physical exercise. On the one hand, physical activity and doing it in groups are limited for children, and on the other hand, they are provided with a variety of food resources in terms of entertainment. Predictions consistent with the culture and home facilities of Iranians demonstrate that not attending school can lead to more eating foods (8), junk foods, and/or miss meals (8) among children of school ag","PeriodicalId":13969,"journal":{"name":"International Journal of Endocrinology and Metabolism","volume":null,"pages":null},"PeriodicalIF":2.1,"publicationDate":"2020-12-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/70/1c/ijem-19-1-110634.PMC8010564.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"25568952","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Iranian Endocrine Society Guidelines for Screening, Diagnosis, and Management of Gestational Diabetes Mellitus.","authors":"Majid Valizadeh,&nbsp;Farhad Hosseinpanah,&nbsp;Fahimeh Ramezani Tehrani,&nbsp;Hengameh Abdi,&nbsp;Ladan Mehran,&nbsp;Farzad Hadaegh,&nbsp;Atieh Amouzegar,&nbsp;Farzaneh Sarvghadi,&nbsp;Fereidoun Azizi","doi":"10.5812/ijem.107906","DOIUrl":"https://doi.org/10.5812/ijem.107906","url":null,"abstract":"<p><strong>Context: </strong>Gestational diabetes mellitus (GDM) is an important endocrine disorder in perinatology, associated with several maternal and neonatal complications. Development of national guidelines can inform clinicians, health policymakers, and researchers about the most recent evidence and practical issues of diagnosis and management of GDM.</p><p><strong>Objectives: </strong>We aimed to develop clinical practice guidelines for the diagnosis and management of GDM in Iranian pregnant women.</p><p><strong>Evidence acquisition: </strong>The Iranian Endocrine Society constituted a task force, consisting of obstetrician-gynecologists, endocrinologists, a clinical nutritionist, a clinical epidemiologist, and a librarian, to review the published literature and propose national guidelines for the diagnosis and management of GDM. The consensus was reached on all recommendations in several group meetings with a majority decision. The evidence and recommendations were graded according to the American College of Physicians' Guideline Grading System.</p><p><strong>Results: </strong>The proposed guidelines included recommendations for screening, diagnosis, and management of GDM in Iran.</p><p><strong>Conclusions: </strong>By using an evidence-based approach, these national GDM guidelines can address important clinical issues in the diagnosis and management of Iranian women with GDM.</p>","PeriodicalId":13969,"journal":{"name":"International Journal of Endocrinology and Metabolism","volume":null,"pages":null},"PeriodicalIF":2.1,"publicationDate":"2020-12-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/8b/bd/ijem-19-1-107906.PMC8010429.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"25574089","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Scientific Publishing in Biomedicine: How to Choose a Journal?","authors":"Zahra Bahadoran,&nbsp;Parvin Mirmiran,&nbsp;Khosrow Kashfi,&nbsp;Asghar Ghasemi","doi":"10.5812/ijem.108417","DOIUrl":"https://doi.org/10.5812/ijem.108417","url":null,"abstract":"<p><p>Publishing in peer-reviewed high-quality journals is a gold standard method for disseminating scientific work. Choosing the right journal is one of the most important and difficult aspects of publishing research results. Submitting to an inappropriate journal is one of the most common reasons for fast rejection of manuscripts, resulting in time wasted by the authors and journals' editors. Here, we discuss important factors that should be considered for choosing the right journal to get your work published successfully and effectively. The most important factors for journal targeting are: (1) The journal's characteristics, including its scientific prestige, performance, publishing model, acceptance possibility, and specialty; (2) the manuscript's characteristics, including its relevance to the journal's aim and scope, its intrinsic value, meaning the novelty of the research, soundness of the methodology, potential impact in the field, and its implication; and (3) authors' priorities and limitations.</p>","PeriodicalId":13969,"journal":{"name":"International Journal of Endocrinology and Metabolism","volume":null,"pages":null},"PeriodicalIF":2.1,"publicationDate":"2020-11-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/51/27/ijem-19-1-108417.PMC8010430.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"25574090","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Comparison of the Modification of Diet in Renal Disease Study and Chronic Kidney Disease Epidemiology Collaboration Equations for Detection of Cardiovascular Risk: Tehran Lipid and Glucose Study.","authors":"Pouria Mousapour,&nbsp;Maryam Barzin,&nbsp;Majid Valizadeh,&nbsp;Maryam Mahdavi,&nbsp;Fereidoun Azizi,&nbsp;Farhad Hosseinpanah","doi":"10.5812/ijem.101977","DOIUrl":"https://doi.org/10.5812/ijem.101977","url":null,"abstract":"<p><strong>Objectives: </strong>The study aimed to compare the Modification of Diet in Renal Disease Study (MDRD) and the Epidemiology Collaboration (CKD-EPI) equations for the detection of cardiovascular risk.</p><p><strong>Methods: </strong>Data of 9,970 Tehranian participants aged ≥ 20 years were analyzed. The prevalence of cardiovascular disease (CVD), its risk factors, and 10-year atherosclerotic cardiovascular disease (ASCVD) risk were compared across the categories of glomerular filtration rate based on the MDRD and CKD-EPI equations. Chronic kidney disease (CKD) was defined as the estimated Glomerular Filtration Rate (eGFR) < 60 mL/min/1.73 m² according to each equation.</p><p><strong>Results: </strong>The prevalence of CKD weighted to the 2016 Tehranian urban population was 11.0% (95% confidence interval: 10.3 - 11.6) and 9.7% (9.1 - 10.2) according to the MDRD and CKD-EPI equations, respectively. Besides, 8.3% and 1.5% of the participants with CKD_MDRD and non-CKD_MDRD were reclassified to non-CKD_CKD-EPI and CKD_CKD-EPI categories, respectively. Participants with CKD_CKD-EPI but without CKD_MDRD were more likely to be male and older, and more frequently had diabetes, hypertension, dyslipidemia, and CVD, when compared to those without CKD according to both equations; they were also more likely to be male, older, and smokers, and had less dyslipidemia and more CVD, when compared to those with CKD by using both equations. In multivariate logistic regression analysis, compared to CKD_MDRD, the odds of CKD_CKD-EPI were significantly higher for older age and lower for the female gender.</p><p><strong>Conclusions: </strong>Compared to MDRD, the CKD-EPI equation provides more appropriate detection of cardiovascular risk, which is caused by the reclassification of older individuals and fewer females into lower eGFR categories.</p>","PeriodicalId":13969,"journal":{"name":"International Journal of Endocrinology and Metabolism","volume":null,"pages":null},"PeriodicalIF":2.1,"publicationDate":"2020-11-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/ed/66/ijem-18-4-101977.PMC7887458.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"25390710","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Theater Performing Arts (TPA): Community Empowerment to Improve Blood Glucose Control Behavior in Yogyakarta.","authors":"Mahendro Prasetyo Kusumo,&nbsp;Julita Hendrartini,&nbsp;Zaenal Muttaqien Sufro,&nbsp;Fatwa Sari Tetra Dewi Dewi","doi":"10.5812/ijem.103106","DOIUrl":"https://doi.org/10.5812/ijem.103106","url":null,"abstract":"<p><strong>Background: </strong>Poor self-management behavior is one of the causes of the high number of patients with type 2 diabetes mellitus (T2DM) in Indonesia.</p><p><strong>Objectives: </strong>The aim of this study was to measure the effectiveness of TPA-based community empowerment as a form of education in improving the blood glucose control practices of patients with T2DM in Yogyakarta.</p><p><strong>Methods: </strong>This study used quantitative methods with a quasi-experimental non-equivalent pre-posttest control group design. The subjects of this study were \"Prolanis member\" patients with T2DM in the four primary health care centers in Sleman, Yogyakarta, Indonesia. Purposive sampling was done at four primary care in Sleman, Yogyakarta, Indonesia. From 138 T2DM patients, only 102 were eligible to become respondents. The questionnaires were adapted to the recommendations of endocrine experts' associations to measure the level of T2DM patients' knowledge, attitude and practices. Intervention was done for three months, from October to December 2019. Measurements were made before and after the TPA.</p><p><strong>Results: </strong>Attitude and behavior scores showed a significant increase (P < 0.05) after TPA intervention. Meanwhile, the average score of knowledge after the TPA intervention showed no significant increase (P > 0.05). Good self-management behavior in patients with T2DM was observed in Sleman Regency. Education through TPA based community empowerment should be considered as an appropriate intervention to improve DM management practice. Patients can receive material that is delivered easily because of the relaxed and pleasant environment during TPA.</p><p><strong>Conclusions: </strong>TPA-based community empowerment can create a relaxed and pleasant environment to improve blood glucose control practices in patients with T2DM.</p>","PeriodicalId":13969,"journal":{"name":"International Journal of Endocrinology and Metabolism","volume":null,"pages":null},"PeriodicalIF":2.1,"publicationDate":"2020-11-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/80/f3/ijem-18-4-103106.PMC7887461.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"25390711","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}