International Journal of Cosmetic Science最新文献

{"title":"Enhancement of water homeostasis by glycerol and urea in stratum corneum and the difference in the activity between them.","authors":"Ryosuke Toyoshima, Kenji Murashima, Ichiro Hatta","doi":"10.1111/ics.13069","DOIUrl":"https://doi.org/10.1111/ics.13069","url":null,"abstract":"<p><strong>Objective: </strong>To investigate the role of glycerol and urea in water-holding mechanisms in the stratum corneum (SC) using synchrotron X-ray diffraction and to clarify differences in activity.</p><p><strong>Methods: </strong>Structural changes in human SC samples treated with water, glycerol, and urea aqueous solutions were measured during drying, focusing on the short lamellar, orthorhombic hydrocarbon-chain packing, and coiled-coil α-helix structure of the soft keratin, which are affected by water.</p><p><strong>Results: </strong>During drying of the treated SC, the coiled-coil α-helix chain distance decreased due to the removal of bound water. The reduction rate was suppressed in the SC treated with glycerol, followed by those treated with urea. This result suggests that water binding via glycerol is strongest to soft keratin, followed by urea. Furthermore, for the short lamellar structure, we calculated the volume associated with the hydrocarbon chain, its head group, and water in the head group, from which we estimated the quantity of water removal. Initially, the volume was unchanged because no water was removed. Once the SC was treated with glycerol and urea, the volume-unchanged interval was longer than that in the SC treated with water alone. Therefore, glycerol and urea strengthened water retention within the water layer.</p><p><strong>Conclusion: </strong>Taken together with the results obtained from the solid-state NMR analysis of the soft keratin, the present results indicate that glycerol enhances the retention of the maximum bound water of 25 wt% in the SC, whereas urea retains it somewhat weakly. Therefore, from the results of in vivo confocal Raman microscopy, which indicated that the water content near the surface of the normal skin is approximately 25 wt%, it is deduced that the maximum bound water content is strongly held at the skin surface with the aid of glycerol or urea. On the other hand, it was found that the lipid lamellar structure serves to regulate the water content to maintain it at 25 wt% and glycerol and urea work to enhance this regulation mechanism. Owing to the above two mechanisms, the water content at the skin surface is maintained at 25 wt% homeostatically, and the homeostatic state is strengthened by glycerol and urea.</p>","PeriodicalId":13936,"journal":{"name":"International Journal of Cosmetic Science","volume":" ","pages":""},"PeriodicalIF":2.7,"publicationDate":"2025-05-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144110559","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Indirubin as a red hair Colourant from Indigofera tinctoria L.","authors":"Skrollan Klaas, Volkmar Vill, Fabian Straske","doi":"10.1111/ics.13076","DOIUrl":"https://doi.org/10.1111/ics.13076","url":null,"abstract":"<p><strong>Objective: </strong>Detailed understanding of the indigo and indirubin synthesis pathway to control their formation and the corresponding colour result on hair should be obtained. Managing the formation of the dye molecules indigo and indirubin the characteristic colour shift which takes place within the days after application of Indigofera tinctoria L.-based hair colouration should be eliminated. Thus, intense, more reliable and stable colour results on hair from the natural resource I. tinctoria L. are achieved offering benefits to the consumer resulting in higher acceptance of plant-based colouration products.</p><p><strong>Methods: </strong>Various colourations with I. tinctoria L. crushed leaves powder and cysteine, isatin or ascorbic acid on yak hair strands were carried out at room temperature or 37°C. Colour assessment was conducted with L*-, a*-, and b*-values/coordinates of three-dimensional CIE-Lab-colour. Coloured hair strands were pulverized with a ball mill to extract dyeing compounds from hair fibres with either a mixture of ultrapure water and acetonitrile or dimethyl sulfoxide at 80°C. Afterwards, the supernatant was collected, and dyeing compounds were quantified via high-performance liquid chromatography.</p><p><strong>Results: </strong>It was proven that delayed development of indirubin in addition to the directly formed indigo molecule leads to the observed colour shift on hair fibres when dyeing them with I. tinctoria L. Further, a previously unseen, immediate formation of a stable red colour result was achieved by introducing isatin and cysteine or ascorbic acid to the dyeing procedure. By extraction and subsequent analysis of the dye molecules from the coloured hair fibres, it was confirmed that the addition of isatin and a reducing agent to indigo dyeing prevents the formation of the indigo molecule and favours the formation of indirubin.</p><p><strong>Conclusion: </strong>Based on the findings, including the instant formation of indirubin instead of the indigo molecule in the presence of isatin and cysteine or ascorbic acid causing an immediate stable red colour result after the application of I. tinctoria L. on hair, a revised indigo and indirubin synthesis pathway for I. tinctoria L. application including the effect of said additives to the colour outcome is presented.</p>","PeriodicalId":13936,"journal":{"name":"International Journal of Cosmetic Science","volume":" ","pages":""},"PeriodicalIF":2.7,"publicationDate":"2025-05-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144119706","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"The effects of caffeine and adenosine on the microbiome and lipidome of the scalp.","authors":"Fengzhu Li, Shulin Liu, Zhaoying Han, Yingtian Li, Haowei Chen, Qingying Shi, Jie Tan, Xihong He, Xinyan Liu, Huabing Zhao, Fang Wang","doi":"10.1111/ics.13072","DOIUrl":"https://doi.org/10.1111/ics.13072","url":null,"abstract":"<p><p>Hair loss is a complex multifactorial process. The mechanisms by which caffeine and adenosine act against hair loss have been extensively researched, but little is known about their effects on the microbiome and lipidome of the scalp. Hair loss may be associated with the status of scalp microbiota and lipids. Further investigation is warranted to determine whether caffeine and adenosine can regulate scalp microbiota and lipids and thus help to prevent hair loss. The objective of this study was to assess the effect of shampoo containing caffeine and adenosine on the scalp microbiome and lipidome in subjects experiencing hair loss who were aged between 18 and 60 years. The study was a randomized, single-blind and parallel comparison trial involving full scalp treatment, which was conducted among 30 subjects experiencing hair loss. Samples were collected from subjects at baseline and at 12 weeks (±3 days). Microbiomes were analysed via 16S rDNA and ITS1 sequencing. Lipidome analysis was carried out using ultra-high performance liquid chromatography-tandem mass spectrometry (UPLC-MS/MS). At 12 weeks, significant clinical characteristics indicating an anti-hair loss effect were evident. Abundances of Pseudomonas, Escherichia-Shigella and Malassezia all decreased in the experimental group, whereas those of Talaromyces and Cutibacterium increased. In addition, levels of triglyceride (TG), diglyceride (DG), ceramide (Cer) and ceramide-1-phosphate (CerP) were all significantly impacted in the experimental group. Furthermore, abundances of lipid metabolites were tightly correlated with those of Escherichia-Shigella and Talaromyces. Caffeine and adenosine may enhance the anti-hair loss process through their effects on the lipidome and microbiome of the scalp.</p>","PeriodicalId":13936,"journal":{"name":"International Journal of Cosmetic Science","volume":" ","pages":""},"PeriodicalIF":2.7,"publicationDate":"2025-05-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144110567","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Characterizing the skin of Thai women and its glow by combining consumer assessments and instrumental methods.","authors":"Rashmi Kelkar, Rima Rakshit, Hemali Pandya, Mohammedali Sajun, Neha Sirkek, Agrawal Divya, Muller Benoit, Flament Frederic","doi":"10.1111/ics.13071","DOIUrl":"https://doi.org/10.1111/ics.13071","url":null,"abstract":"<p><strong>Background: </strong>The main objective of this research work is to understand how skin glow is perceived by women in Thailand. As the market is so rapidly evolving the consumers are clear about their expectations from skin care cosmetic products where they expect glowing skin as a key benefit with whatever skin colour they have.</p><p><strong>Aims: </strong>To decode glow understanding of Thai women MATERIALS AND METHODS: A hybrid consumer and instrumental evaluation study done on Thai women with qualitative interviews of glow-seeking women and then capturing the skin colour, kinetics using instruments before and after using their skincare routine.</p><p><strong>Results: </strong>The research helped to decode that in the Thai women population, dry skin is less prevalent as they perceived their skin to be dry (Corneometer value < 40), while 91% of the population perceived their skin to be normal, with a capacitance value ranging 55-62 units. In terms of skin colour of these women, it represents skin tone clusters Light warm, Light cool and Medium tones.</p><p><strong>Discussion: </strong>From this research, we also understand the attributes linked to ideal skin glow are shine, suppleness and even skin, along with what key product deliverables are required to meet the consumer expectation.</p><p><strong>Conclusion: </strong>The present study indicates some specificities of Thai consumers, whose expectations seem slightly different from other Asian needs. However this work is limited only to the immediate effects of cosmetic products. It is worth investigating further the long-term effects on the evolution of glow, the efficacy of different products that can best improve the facial glow to address the skin concerns and its correlation with the routine that is relevant to consumers.</p>","PeriodicalId":13936,"journal":{"name":"International Journal of Cosmetic Science","volume":" ","pages":""},"PeriodicalIF":2.7,"publicationDate":"2025-05-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144101852","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"A new in vitro approach for determining the water resistance of sunscreen products, validated by a blinded ring test.","authors":"M Pissavini, F Pouradier, G Wiener, M Contier, L Kolbe, L Nogueira, P Lapalud, G Renner, P J Matts","doi":"10.1111/ics.13074","DOIUrl":"https://doi.org/10.1111/ics.13074","url":null,"abstract":"<p><p>Despite limited consumer understanding of sunscreen labelling, product choice remains primarily driven by the labelled Sun Protection Factor (SPF), alongside UVA protection and water resistance claims. To ensure the reliability of these key parameters, validated and reproducible testing methods are essential. In response to recent ISO publications on in vivo water resistance evaluation, the Cosmetics Europe Sun Protection Methods Task Force has initiated the development of a robust in vitro alternative. Current in vitro approaches are based on thin-film UV transmittance techniques, but their accuracy is highly sensitive to film homogeneity, both during application and after immersion. It has been shown that immersion can induce film rearrangement, altering UV absorbance without necessarily reducing active ingredient content. This may lead to atypical results, including apparent increases in SPF values post-immersion. Here, in a ring-testing approach, we investigate a new method for determining the in vitro water resistance of sunscreen products. This study aims to identify the most robust and predictive in vitro alternative, contributing to the development of a standardized and scientifically reliable method for water resistance assessment in sunscreen products.</p>","PeriodicalId":13936,"journal":{"name":"International Journal of Cosmetic Science","volume":" ","pages":""},"PeriodicalIF":2.7,"publicationDate":"2025-05-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144101850","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Pleiotropic effects of a Camellia sinensis leaf extract on in vitro and in vivo skin health characteristics.","authors":"Daniel D Shill, Hannah N Stade, Kayla C Goodson, Monica A Beltran, Deana Haller, Meg Benson, Maureen D Drumwright, Durant Scholz","doi":"10.1111/ics.13073","DOIUrl":"https://doi.org/10.1111/ics.13073","url":null,"abstract":"<p><strong>Objective: </strong>Green tea extracts are utilized widely within the pharmaceutical and cosmetic industries given the large amount of evidence supporting a diverse range of health benefits. The cosmetic effects of green tea extracts depend on manufacturing methods, and a viable green tea extract exhibiting a diverse functional portfolio to meet consumer demands for comprehensive skin benefits is lacking. To fully capture the diverse nature of skincare products, a novel assay was developed to identify the impact of green tea extracts on the relationship between immune cell function and dermal microorganisms. Accordingly, the present study investigated the effect of a Camellia sinensis Leaf Extract (CSLE) on in vitro mechanisms and in vivo indicators of skin health and well-being. This study provides the first evidence of CSLE's immunomodulatory properties on skin microorganisms via dendritic cell signalling molecules, in addition to enhancing relaxation through alpha brainwave activity with topical CSLE application.</p><p><strong>Methods: </strong>In vitro and in chemico pre-clinical experiments were implemented to determine the immunomodulatory, detoxification, anti-inflammatory and antioxidant properties of CSLE. Additionally, in vivo clinical studies were performed to examine the impact of topical CSLE application on acute and residual mood states, skin hydration, barrier function, rejuvenation and facial skin health.</p><p><strong>Results: </strong>Pre-clinical investigations illustrated CSLE augmented the ability of signalling molecules released from dendritic cells to kill detrimental microorganisms while maintaining commensal microorganisms commonly found on the skin. Furthermore, CSLE increased cellular detoxification, reduced inflammation and exhibited potent antioxidant capacity. Regarding clinical studies, acute topical CSLE application enhanced relaxation and improved residual feelings of self-worth and mood while augmenting skin hydration, barrier function and rejuvenation. Moreover, long-term CSLE application improved facial skin health and lowered skin age.</p><p><strong>Conclusion: </strong>Collectively, CSLE retains detoxification, anti-inflammatory and antioxidant properties while improving mood states, skin hydration, skin barrier function, skin rejuvenation and facial skin health. Notably, we provide the first evidence of CSLE's immunomodulatory properties on skin microorganisms via dendritic cell signalling molecules, in addition to enhancing relaxation through alpha brainwave activity with topical CSLE application. Overall, the present investigation demonstrates CSLE elicits a diverse and comprehensive efficacy portfolio for utilization in skincare products.</p>","PeriodicalId":13936,"journal":{"name":"International Journal of Cosmetic Science","volume":" ","pages":""},"PeriodicalIF":2.7,"publicationDate":"2025-05-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144110564","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"n-3 PUFAs docosahexaenoic acid and eicosapentaenoic acid are effective natural pro-resolution ingredients for topical skin applications.","authors":"John Nip, Kevin Hermanson, Jian-Ming Lee","doi":"10.1111/ics.13068","DOIUrl":"https://doi.org/10.1111/ics.13068","url":null,"abstract":"<p><p>Skin encounters many challenges that lead to an inflammatory response. Resolution of this inflammation is needed to return the skin to a healthy state. A review of the role of topical n-3 PUFAs, particularly DHA and EPA, in resolving skin inflammation and promoting skin health is presented. A review of the literature and Unilever data on DHA/EPA pro-resolution skin benefits. PubMed/MEDLINE, Google search of external literature as well as Unilever data relating to skin inflammation, pro-resolution, and the role of DHA and EPA. Evidence of DHA and EPA in providing pro-resolution of skin inflammation are summarized. DHA and EPA, and their derived specialized pro-resolving mediators (SPMs), can attenuate the skin inflammatory response induced by various stressors and maintain skin health.</p>","PeriodicalId":13936,"journal":{"name":"International Journal of Cosmetic Science","volume":" ","pages":""},"PeriodicalIF":2.7,"publicationDate":"2025-04-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143997912","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Development of the Hair & Scalp CARE questionnaire: Measuring the impact of hair and scalp issues on psychological wellbeing in healthy populations.","authors":"Alice Newton-Fenner, William M Hirst, Therese Jones, Margaret Scott, Carl Roberts, Monique A M Smeets, Jeremy Shen, Anna Thomas, Timo Giesbrecht","doi":"10.1111/ics.13070","DOIUrl":"https://doi.org/10.1111/ics.13070","url":null,"abstract":"<p><strong>Objective: </strong>Haircare cosmetic products are commonly reported to have a positive impact on psychological wellbeing. These effects are attributed to increased feelings of confidence and improved self-esteem facilitated by improved hair and scalp condition. However, the causal relationship between hair and scalp health and psychological wellbeing is under-researched. This paper reports the results of an extensive survey of haircare consumers in diverse populations using an exploratory Hair & Scalp CARE (Condition and Affective Response Evaluations) questionnaire.</p><p><strong>Method: </strong>Participants (N = 1184) completed an online 23-item questionnaire designed to capture hair and scalp-related wellbeing as an initial exploratory validation of Hair & Scalp CARE. For the analysis, the data were randomly split into 2 equal samples; Sample 1 provided the data for the initial exploratory factor analysis, and Sample 2 was used for confirmatory factor analysis. Participants also provided demographic information and completed the Sleep Health Index (SHI) and Perceived Stress Scale (PSS) to investigate sleep health and perceived stress.</p><p><strong>Results: </strong>Factor analysis provided a one-factor solution, explaining 55% of the variance. The final version of the Hair & Scalp CARE questionnaire consisted of 21 items. The one-factor structure was supported by confirmatory factor analysis. Correlational analyses demonstrated that higher scores on Hair & Scalp CARE were also associated with lower PSS scores and higher SHI scores.</p><p><strong>Conclusion: </strong>The Hair & Scalp CARE questionnaire is a valid tool for the assessment of the impact of hair and scalp condition on psychological wellbeing. The present data also suggest a relationship between hair and scalp wellbeing and other psychological wellbeing indicators, as healthier hair and scalp was also linked to lower levels of perceived stress and good sleep health. Hair & Scalp CARE could be used within a variety of further research designs to demonstrate the positive impact of cosmetic haircare products on wellbeing.</p>","PeriodicalId":13936,"journal":{"name":"International Journal of Cosmetic Science","volume":" ","pages":""},"PeriodicalIF":2.7,"publicationDate":"2025-04-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143998971","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Mining bioactive components in agricultural crop and food production residue for sustainable solutions: In silico screening for skin anti-ageing properties.","authors":"Senka Vidović, Milan Ilić, Jelena Nakomčić, Nataša Nastić, Jelena Kvrgić, Xuanpeng Song, Dimitar Jakimov, Aleksandra Jovanović Galović, Nataša Lješković Jovanović, Mire Zloh","doi":"10.1111/ics.13059","DOIUrl":"https://doi.org/10.1111/ics.13059","url":null,"abstract":"<p><p>Possible sustainable resources of beneficial compounds for various applications are agricultural crop and food production residues (ACFPR), which are supported by considerable efforts to characterize their compositions and biological activities. This knowledge can be utilized for the rational selection of agricultural crop residue extracts and their components and possible use in the development of value-added products, such as anti-ageing cosmetics. The appearance of wrinkles, pigmentation, and a reduction in skin elasticity are typical signs of ageing skin that are often alleviated by natural product-based preparations. Here, we use in silico approaches to identify natural compounds from agricultural crop and food production residues with the potential to alleviate symptoms of or reverse the skin ageing process. Target predictions combined with extensive database and literature searches were utilized to identify compounds present in ACR and proteins linked to skin ageing. The binding affinity of natural products to selected proteins using molecular docking and the respective intermolecular interaction analyses are predicted to provide an indicative measure of the compounds' potential for skin anti-ageing activity. A number of natural compounds with the potential to interact with protein targets such as collagenase, elastase, and hyaluronidase were identified. In addition to in silico findings, cytotoxicity assays were conducted using rose hip seed extracts against Hs294T (human metastatic melanoma, ATCC HTB-140) and MRC-5 (normal fetal lung fibroblasts, ATCC CCL 171), demonstrating selective cytotoxicity. ELISA assays revealed that rose hip seed extracts induced a significant increase in SIRT1 levels (160% of control) and a reduction in TGF-β levels (80% of control). These experimental results support the potential of agricultural crop residue extracts in modulating key proteins involved in skin ageing, reinforcing their viability as ingredients in anti-ageing cosmetic formulations. An analysis of the molecular relationships and pathways that organic substances from sustainable sources can affect offers the potential for developing formulations for skin rejuvenation with possible synergistic effects by utilizing the rational design of innovative skincare products and laying the framework for more effective screening of anti-ageing compounds for different applications.</p>","PeriodicalId":13936,"journal":{"name":"International Journal of Cosmetic Science","volume":" ","pages":""},"PeriodicalIF":2.7,"publicationDate":"2025-04-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143984871","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"A non-invasive way to enhance cosmetic efficacy by associating a cosmetic serum with a nanochip tapping.","authors":"Chengda Ye, Chunyao Lu, Frederic Flament, Jing Li, Gaurav Agarwal, Gregoire Charraud, Angelike Galdi, David Amar, Wei Liu, Qing Lv, Bai Xu, Guive Balooch, Maxime De Boni","doi":"10.1111/ics.13056","DOIUrl":"https://doi.org/10.1111/ics.13056","url":null,"abstract":"<p><strong>Background: </strong>Skincare cosmetics have long been central to daily facial care routines, while recent years have seen a surge in the popularity of home beauty devices. Consumers increasingly seek more effective and efficient results from their beauty regimens while also expressing concerns about the potential risks of certain beauty procedures. Although various technological devices have been developed to meet these demands, research on the interactions between beauty devices and cosmetic products remains limited.</p><p><strong>Methods: </strong>This in vivo study was conducted on 60 Chinese women of different ages and skin types. An assessment of the impact of a specific home beauty device, used after a standalone referential and marketed anti-ageing serum, on enhancing facial skin attributes (wrinkles, fine lines, radiance and hydration) was conducted. The device-a nanochip tapping tool with an ultra-fine surface-was evaluated alongside the serum under a half-face protocol. The study compared the efficacy of serum application alone to that achieved with the combined serum-device regimen.</p><p><strong>Results: </strong>Marked reduction in ageing signs was reported for the serum alone, particularly for wrinkles (p < 0.001), fine lines (p < 0.001), radiance (p < 0.001) and hydration (p < 0.001) after 8 weeks. When paired with the nanochip device, efficacy was significantly amplified and enhanced global wrinkle reduction, nasolabial fold smoothness and firmness. There were no adverse effects on SC integrity, confirming that the serum-nanochip application preserved the integrity of the skin. All subjects found the nanochip easy to use and indicated perceived benefits.</p><p><strong>Conclusion: </strong>The present study showed that the use of a nano-needle tapping device led to significantly enhanced global efficacy on some age-related facial signs under safe and skin-friendly conditions. This study highlights that the dual focus on merging both efficacy and safety was not only effective but also safe for use, thereby setting a solid foundation for future research and development.</p>","PeriodicalId":13936,"journal":{"name":"International Journal of Cosmetic Science","volume":" ","pages":""},"PeriodicalIF":2.7,"publicationDate":"2025-04-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144011000","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}