International Journal of Pharmaceutical Chemistry and Analysis最新文献_第5页

Mechanism and management of antibiotic drug resistance tuberculosis 抗生素耐药结核的发生机制及防治

International Journal of Pharmaceutical Chemistry and Analysis Pub Date : 2022-10-15 DOI: 10.18231/j.ijpca.2022.020

Chiragkumar J. Gohil, K. Parmar, Priyanka R. Patel, Jignakumari J. Gohil

引用次数: 0

Current awareness and knowledge of olive oil 目前对橄榄油的认识和知识

International Journal of Pharmaceutical Chemistry and Analysis Pub Date : 2022-08-15 DOI: 10.18231/j.ijpca.2022.011

W. Elkhateeb, Amtul Noor, A. Rashid, A. Bilal, Ghulam Musharaf, Muhammad Akram, Kainat Zafar, G. Daba

{"title":"Current awareness and knowledge of olive oil","authors":"W. Elkhateeb, Amtul Noor, A. Rashid, A. Bilal, Ghulam Musharaf, Muhammad Akram, Kainat Zafar, G. Daba","doi":"10.18231/j.ijpca.2022.011","DOIUrl":"https://doi.org/10.18231/j.ijpca.2022.011","url":null,"abstract":"The olive tree is an unpredictable formed tree, which grows up to 10 m in stature. The olive leaves are inverse and elongated molded. The leaves are dim green above and gleaming beneath. The white and relatively little olive blossoms are shaped on a year ago's wood. The run of the mill natural products or olives are ovoid formed and regularly pointed. This study aimed to see if health signals influenced consumers' decisions of olive oil with varying levels of information about the oil's beneficial characteristics. In order to accomplish this, a direct poll on the use of olive oil was conducted by looking at the expressed preferences of a sample of users. Two economically measured examinations were conducted to determine the factors that influence the use of high-polyphenol olive oil. Furthermore, the data demonstrate that varying levels of personal knowledge have a role in shaping olive oil customers' health perceptions. Finally, this study confirmed that consumers' selections are heavily influenced by their sense of self-coherence, even with healthful foods. As a result, different reasons and traits impact customers' knowledge or beliefs that shape their attitudes.","PeriodicalId":13889,"journal":{"name":"International Journal of Pharmaceutical Chemistry and Analysis","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2022-08-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"79004121","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Method development and validation of ibuprofen obtained from the extraction of bougainvillea campanulata flowers by UV spectrophotometry, FTIR and TLC method 方法采用紫外分光光度法、红外光谱法和薄层色谱法对九重葛花提取物中布洛芬的含量进行验证

International Journal of Pharmaceutical Chemistry and Analysis Pub Date : 2022-08-15 DOI: 10.18231/j.ijpca.2022.015

P. Paul, A. Monika

{"title":"Method development and validation of ibuprofen obtained from the extraction of bougainvillea campanulata flowers by UV spectrophotometry, FTIR and TLC method","authors":"P. Paul, A. Monika","doi":"10.18231/j.ijpca.2022.015","DOIUrl":"https://doi.org/10.18231/j.ijpca.2022.015","url":null,"abstract":"The present study was aimed to develop and validate a simple, accurate, precise, reproducible UV-Visible spectrophotometric method and FTIR for the estimation of Ibuprofen present in extract. The solvent used in the experiment was m. Absorption maximum (λmax) of the drug was found to be 264 nm. The Beer’s law was obeyed in the range of 100-500 μg/ml. The method was shown linear in the mentioned concentrations having line equation y = 0.000023x with correlation coefficient r of 1 The amount of ibuprofen present in the extract was found to be 7 ug/ml. The recovery values for ibuprofen present in Bougainvillea Campanulata flowers extract ranged from 85.9%-87.6%. The percent relative standard deviation (RSD %) of interday precision was 51.35 % and intraday precision was 42.95 %. The limit of detection and limit of quantification was 0.9 μg/mL and 2.7 μg/mL. The percent relative standard deviation of robustness of the method was 37.43-45.86. Hence, proposed method was precise, accurate and cost effective. This method could be applicable for quantitative determination of the methanol present in Bougainvillea flowers extract.","PeriodicalId":13889,"journal":{"name":"International Journal of Pharmaceutical Chemistry and Analysis","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2022-08-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"90699846","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Selectively targeting the cancer cells by reactivating the cell killing function of p53 protein 通过重新激活p53蛋白的细胞杀伤功能，选择性靶向癌细胞

International Journal of Pharmaceutical Chemistry and Analysis Pub Date : 2022-08-15 DOI: 10.18231/j.ijpca.2022.010

Chiragkumar J. Gohil, Jignakumari J. Gohil

引用次数: 0

To study the efficacy of AG CUFFILL (Digital) compared to that of standard PORTEX cuff inflator/pressure analog gauge for the measurement of endotracheal tube cuff pressure 目的:比较AG CUFFILL (Digital)与标准PORTEX袖口充气机/压力模拟计测量气管内管袖口压力的效果

International Journal of Pharmaceutical Chemistry and Analysis Pub Date : 2022-08-15 DOI: 10.18231/j.ijpca.2022.017

A. Shetti, Veena Vijayakumar, Bhavika Singla

{"title":"To study the efficacy of AG CUFFILL (Digital) compared to that of standard PORTEX cuff inflator/pressure analog gauge for the measurement of endotracheal tube cuff pressure","authors":"A. Shetti, Veena Vijayakumar, Bhavika Singla","doi":"10.18231/j.ijpca.2022.017","DOIUrl":"https://doi.org/10.18231/j.ijpca.2022.017","url":null,"abstract":"Endotracheal tube (ETT) is commonly used to provide positive pressure ventilation. ETT cuff pressure is maintained within a range of 20 to 30 cmH2O. High pressure affects micro-circulation and integrity of the tracheal mucosa, resulting in complications. The cuff pressure is measured by connecting a pressure gauge device to pilot balloon. Two variety devices are available; analog or digital manometers. Present study is used to study the efficacy of AG CUFFILLL (Digital) compared with standard PORTEX Cuff inflator/pressure gauge (Analog) for the measurement of ETT cuff pressure.This study was conducted after obtaining institutional ethical clearance and written informed consent.100 patients between the age of 18-70yrs who fulfilled inclusion criteria. We measured ETT cuff pressure using AG CUFFILL (Digital) and standard PORTEX Cuff inflator/pressure gauge and compared the pressure recording of the two equipment and we studied ease of use for both.Out of 100 patients between the age of 18-70yrs, 61 patients (61%) were male and 39 patients (39%) were female. Mean cuff pressure of ETT using AG CUFFILL was 36.29±6.36 cmH2O and in PORTEX was 33.97±6.16cm H2O. Mean difference in the values between the cuff pressure measured by AG CUFFILL and PORTEX was ± 2.67. Comparing the two devices, it was noticed that in 05 (5%) patients measuring ETT cuff pressure using AG CUFFILL was difficult as the values were fluctuating. Based on results, authors recommend AG CUFFILL for ETT cuff pressure measurement owing to its accuracy, non-bulky, and ease to carry.","PeriodicalId":13889,"journal":{"name":"International Journal of Pharmaceutical Chemistry and Analysis","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2022-08-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"73418943","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Formulation of herbal ointment for assessment of wound healing activity from leaves 用于评估伤口愈合活性的草药软膏的配方

International Journal of Pharmaceutical Chemistry and Analysis Pub Date : 2022-08-15 DOI: 10.18231/j.ijpca.2022.013

S. S. Shaikh

引用次数: 0

Hexaconazole poisoning - An uncommon poisoning incidence in rural tertiary care and our experience 六康唑中毒——农村三级保健中罕见的中毒发生率及我们的经验

International Journal of Pharmaceutical Chemistry and Analysis Pub Date : 2022-08-15 DOI: 10.18231/j.ijpca.2022.018

A. Shetti, D. D. Patel, Bhavika Singla

引用次数: 0

Pharmacognostical, phytochemical standardization and anticonvulsant activity study of sesbania grandiflora flowers 大田菁花的生药学、植物化学标准及抗惊厥活性研究

International Journal of Pharmaceutical Chemistry and Analysis Pub Date : 2022-08-15 DOI: 10.18231/j.ijpca.2022.016

S. S. Shaikh

{"title":"Pharmacognostical, phytochemical standardization and anticonvulsant activity study of sesbania grandiflora flowers","authors":"S. S. Shaikh","doi":"10.18231/j.ijpca.2022.016","DOIUrl":"https://doi.org/10.18231/j.ijpca.2022.016","url":null,"abstract":"In the India there is a good biodiversity in plants. Plants based medicinal products used as integrated part of treatment on most of traditional systems of medicines. Sesbania grandiflora is a plant which used traditionally for many medicinal used which belongs in family Fabaceae. Present study was about investigated the Physicochemical and Phytochemical studies on selected plant such as Sesbania grandiflora. For the study Soxhlet apparatus was used for extraction of plant materials with using water, ethanol and chloroform as extractive solvents. Standard chemicals and methods were used for the qualitative determination of plant S. grandiflora flowers extract. The study investigation was followed to determine the presence of chemical compound in flowers part of plant as well as to investigate the quality of drug. Result found that the different flower extract may presence of alkaloids, steroids, tannins, sterols, flavonoid etc. The pentylenetetrazol (PTZ) induced seizure model was used for testing anticonvulsant activity of ethanolic, aqueous and chloroform extracts(100mg/kg) of Sesbania grandiflora flowers. The extracts significantly (*p < 0.01) reduced the duration of convulsion and delay onset of seizure. The study results that Sesbania grandiflora flowers has anticonvulsant activity.","PeriodicalId":13889,"journal":{"name":"International Journal of Pharmaceutical Chemistry and Analysis","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2022-08-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"73804314","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

A validated stability indicating reverses phase liquid chromatographic method for the determination of valacyclovir 反相液相色谱法测定伐昔洛韦的稳定性

International Journal of Pharmaceutical Chemistry and Analysis Pub Date : 2022-08-15 DOI: 10.18231/j.ijpca.2022.012

S. S. Shaikh, V. K. Padri

引用次数: 0

Development of UV spectrophotometric method for estimation of curcumin in bulk drug and nanogel formulation: A hydrolytic degradation studies 紫外分光光度法测定原料药和纳米凝胶制剂中姜黄素含量的研究:水解降解研究

International Journal of Pharmaceutical Chemistry and Analysis Pub Date : 2022-08-15 DOI: 10.18231/j.ijpca.2022.014

M. Rahman

{"title":"Development of UV spectrophotometric method for estimation of curcumin in bulk drug and nanogel formulation: A hydrolytic degradation studies","authors":"M. Rahman","doi":"10.18231/j.ijpca.2022.014","DOIUrl":"https://doi.org/10.18231/j.ijpca.2022.014","url":null,"abstract":"The main purpose of this research was to develop and validate a cost effective UV spectrophotometric method for determination of curcumin in bulk drug and nanogel formulation. The method was validated according to the guideline of International Conference on Harmonisation (ICH). The curcumin was found to be soluble in methanol with λmax of 425 nm. Curcumin over the concentration level of (1-8 µg mL) depicted linear relation in the plot of concentration vs. absorbance. The regression equation of graph was y = 0.1137x - 0.0138 with R value of 0.999. The limits of detection and quantification were 0.23 μg mLand 0.75 μg mL, respectively. The method was accurate, precise, reproducible and robust since all the samples analyzed had relative standard deviation less than 2%. No statistically significant difference between theoretical and measured concentrations was detected. The degradation kinetics of free curcumin (k = 0.042 µg mL.h, 0.53 µg mL.h and 0.068 µg mL.h) and nanogel formulation (k = 0.178 h, 0.003 h and 0.005 h) were zero and first order, respectively. The proposed method was found to be specific while estimating curcumin loaded nanogel formulation without interference of excipients. The developed method was cost effective and can be used for routine quality control analysis of curcumin.","PeriodicalId":13889,"journal":{"name":"International Journal of Pharmaceutical Chemistry and Analysis","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2022-08-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"90641365","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0