International Journal of Advanced Research最新文献

{"title":"AN OBSERVATIONAL STUDY OF EFFECT ON LIPID PROFILE BY SHORT TERM USE OF LOW DOSE STEROID THERAPY IN COMMON ORTHOPAEDIC CONDITIONS","authors":"Maheshkumar Prajapati, Mohammed Sohail Siddiqui, Ravi Patel, Ronak Daglia, Abhinav Vatsa, Charchit Baurasi","doi":"10.21474/ijar01/18267","DOIUrl":"https://doi.org/10.21474/ijar01/18267","url":null,"abstract":"Introduction:Corticosteroids, potent anti-inflammatory drugs used for decades, provide symptomatic relief but carry risks like infection and chronic conditions. Despite complications, theyre prescribed for orthopedic issues. Glucocorticoids influence lipid levels, with conflicting effects. Steroids are termed a double-edged sword. This study aims to assess lipid profile effects of short-term, low-dose steroid therapy in Orthopedics and Rheumatology, evaluating glucocorticoid therapy impact and investigating other effects on musculoskeletal patients. Materials and Methods:This prospective, non-randomized observational study was conducted, focusing on patients with orthopedic and rheumatological issues. Over 150 patients were included, selected through convenient sampling. Inclusion criteria involved patients aged 18-65 without dyslipidemia or cardiovascular conditions, while exclusion criteria included those with specific medical conditions or high BMI. Patients provided written informed consent before undergoing blood tests for lipid profile and blood sugar levels, with vital signs measured. They received Medrol 4 mg thrice daily for ten days, after which outcomes including lipid levels, blood sugar, and blood pressure were assessed. Results:At baseline, 88.67% had desirable cholesterol levels and 11.33% had borderline levels. At follow-up, 20.67% had borderline levels and 79.33% had desirable levels, a statistically significant difference. Mean cholesterol levels decreased from 169.16 ± 19.70 mg/dl to 161.11 ± 27.60 mg/dl, also significant. For triglycerides, 92.67% had normal levels at baseline, decreasing to 65.33% at follow-up, with mean levels increasing from 131.33 ± 6.97 mg/dl to 139.12 ± 23.88 mg/dl. HDL levels showed improvement, with 84.67% having desirable levels at baseline compared to 43.33% at follow-up, with mean levels increasing from 41.09 ± 5.13 mg/dl to 50.71 ± 4.21 mg/dl. LDL levels decreased from 132.43 ± 16.86 mg/dl to 122.59 ± 16.93 mg/dl, with significant changes in distribution. Conclusions:Short-term steroid use for orthopedic conditions affects lipid profiles: Total cholesterol, LDL, and TG rise significantly, countered by increased HDL, offering protection. Long-term effects on lipid profiles and cardiovascular risk require further study. Risk of avascular necrosis due to subtle lipid profile changes also warrants investigation.","PeriodicalId":13781,"journal":{"name":"International Journal of Advanced Research","volume":"77 2","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-02-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140411377","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"UNDERSTANDING MUSCLE CONTRACTION: MECHANISMS AND IMPLICATIONS","authors":"Samaira Mittal","doi":"10.21474/ijar01/18312","DOIUrl":"https://doi.org/10.21474/ijar01/18312","url":null,"abstract":"Muscle contraction is a fundamental physiological process critical for movement, stability, and various bodily functions. This research paper delves into the intricate mechanisms underlying muscle contraction, exploring the role of actin, myosin, calcium ions, and regulatory proteins in the sliding filament theory. Additionally, it discusses the physiological and biochemical aspects of muscle contraction, including the excitation-contraction coupling process and the energy requirements for muscle activity. Furthermore, the paper explores the implications of muscle contraction dysfunction in conditions such as muscular dystrophy and the potential therapeutic interventions. By comprehensively understanding muscle contraction, researchers and clinicians can advance treatments for muscle-related disorders and optimize performance in various fields.","PeriodicalId":13781,"journal":{"name":"International Journal of Advanced Research","volume":"20 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-02-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140415064","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"KNOWLEDGE ATTITUDE AND AWARENESS REGARDING ZNO SUNSCREEN PROTECTION AMONG UNDERGRADUATE DENTAL STUDENTS","authors":"T. Maria Alphonsa Deepthi, K. Pratap, T. Madhavi Padma, V. Siva Kalyan, V. Srujan Kumar","doi":"10.21474/ijar01/18316","DOIUrl":"https://doi.org/10.21474/ijar01/18316","url":null,"abstract":"Background:Zincoxidenanorods were employed as the primary ultra- violet protection agent in the formulation of sunscreens. Examination of ZnO powder through FESEM and TEM micrographs revealed the predominant presence of rod-like structures with a width range between 61-70 nm. Notably, sunscreens containing 20-40% (by weight) of ZnOnanorods exhibited significantly improved UV absorbance across both UVA and UVB spectra (280-400 nm). This study mainly aims to assess the Knowledge Attitude and Awareness Regarding ZnOnanorodsinSunscreenProtectionAmongUndergraduateDentalStudents. Aim: Knowledge Attitude and Awareness Regarding ZnO Sunscreen Protection Among Undergraduate Dental Students. Objective: Analyzing and determining the Knowledge Attitude and Awareness Regarding ZnO Sunscreen Protection Among Undergraduate Dental Students. Method: A cross sectional study was conducted among the dental students (II,III, IV, interns) in a tertiary care teaching hospital,Khammam, using a web basedtool called forms pro, a semi-structural online questionnaire was designed and distributed to the students in order to fill.Descriptive statistics were calculated using SPSS verson-29..A p- value <0.05 was used to evaluate statistical significance. Result: A total of 209 students took part with females (70.8%) and males (29.2%). Age of participants ranges from 19-25 years. In this study female students have more knowledge and awareness regarding ZnO Sunscreen Protection compared to males. Among all the students Interns have more knowledge, followed by IV-BDS, III-BDS and II-BDS. Conclusion: The study result suggests that knowledge and awareness level of ZnO Sunscreen Protection is adequate.","PeriodicalId":13781,"journal":{"name":"International Journal of Advanced Research","volume":"11 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-02-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140416071","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"ANKYLOSIS OF THE TEMPOROMANDIBULAR JOINT","authors":"A. Monteiro, P.B. Mavoungou, M. Nde-Ngala, Y. Ouardi, M. Khallouki","doi":"10.21474/ijar01/18329","DOIUrl":"https://doi.org/10.21474/ijar01/18329","url":null,"abstract":"Introduction: Difficult intubation is a very dreaded situation in anesthesia and is frequently encountered in maxillofacial surgery15.7%(1)particularlyinpatientswithankylosisofthejoint temporomandibular (TMJ) the scarcity of equipment used in the event of difficult intubation (ID) such as that a nasofibroscopy represents a challenge and requires the use of other techniques (2). The interest of our study is to show the importance of capnography and ultrasound guidance during an ID blind nasotracheal. Comment: It concerns the management of the respiratory tract of a patient aged 41 years and 78 kg followed for epilepsy since childhood, substegretol 200mgx2/jet with congenital TMJ ankylosis. On the basis of preoperative clinical and radiological results, we have found the criteria for ID in particular the impossibility of opening the mouth and with the resources available, an intubation nasotracheal surgery under general anesthesia with spontaneous breathing was considered and a written informed consent for an emergency tracheotomy if required has been obtained from the patient. The procedure successively consisted of pre-oxygenation of the facial mask, xylocaine 0.05% a been sprayed into the right nostril, 0.05% xylocaine gargle, blockage of the laryngeal nerves superior by transcutaneous injections of lidocaine 1% and intra-tracheally, then we performed sedation with propofol 50mg. Blind nasotracheal intubation was successful in one uneventful attempt per No. 6.5 mm reinforced probe, the verification was made by visualizing the intra-tracheal probe at through ultrasound and confirmation by capnography. The anesthesia was completed by the administration of fentanyl 250 gamma, propofol 100 mg and rocuronium 40mg. Maintenance of anesthesia was performed by a mixture of isoflurane (1.5%) and oxygen and air (50%:50%). The patient was extubated after the surgical procedure and the operation was a success. Conclusion: The anesthesia of patients with TMJ ankylosis represents a situation where the difficulties tracheal intubation should be considered in principle, and where an anticipatory strategy should be developed. Due to the absence of anasofibroscopy, the anesthetic treatment must be carried out by a team experienced and trained in blind ID.","PeriodicalId":13781,"journal":{"name":"International Journal of Advanced Research","volume":"24 5","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-02-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140412580","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"CULTIVATING SUCCESS: THE TRANSFORMATIVE POWER OF INSPIRATIONAL LEADERSHIP FOR ENTREPRENEURS","authors":"Shwetha T.A, Nitu Ghosh","doi":"10.21474/ijar01/18265","DOIUrl":"https://doi.org/10.21474/ijar01/18265","url":null,"abstract":"Innovative leaders establish psychologically stable settings, facilitate associations, and increased organizations. Businesses nowadays must innovate if they are to thrive and endure in a cutthroat economy. Organizational performance is driven by inspirational leaders.Entrepreneurship research is a fairly new field of research (Cornelius et al., 2006). The foundation and development of start-ups are inevitably connected with leadership. This is unexpected considering how important inspirational leadership is to a start-success. ups Inspiring leadership stimulates innovative and creative thinking and significantly enhances team and individual performance. By appealing to our inner motivation and values and inspiring individuals to follow their passions and ambitious goals, it effectively unlocks hidden potential. This study focuses on shedding light on the inspirational leadership characteristics exhibited by entrepreneurs in India. The primary objective is to conduct a qualitative analysis of the personality profiles of these entrepreneurs, aiming to identify key traits and qualities that contribute to their success. The research specifically emphasizes the importance of emotional intelligence and inspirational leadership abilities in entrepreneurial ventures. By adopting a case-based approach, the study utilizes primary data collected through interviews and focused group discussions. This methodology allows for a comprehensive exploration of the individual experiences and characteristics of entrepreneurs, providing valuable insights into their leadership styles. The qualitative analysis conducted in this study aims to unveil the winning characteristics that entrepreneurs possess, with a particular emphasis on emotional intelligence and inspirational leadership. The findings of the study are expected to offer a deeper understanding of the qualities that make entrepreneurs successful in todays dynamic society. The cases examined in the research highlight how inspirational leadership serves as a guiding force, enabling committed and motivated employees and teams to achieve significant organizational performance. This study contributes to the existing body of knowledge by providing a nuanced exploration of the personality profiles of entrepreneurs, emphasizing the role of emotional intelligence and inspirational leadership in their achievements.","PeriodicalId":13781,"journal":{"name":"International Journal of Advanced Research","volume":"24 2","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-02-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140412583","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"CBCT ANALYSIS OF PULP CHAMBER THICKNESS AND MORPHOLOGY IN PRIMARY MOLARS: AN OBSERVATIONAL STUDY","authors":"Rohan Shrivastava, Sonal Gupta, Asmita Das, Antra Saket, Priyambana Pandey","doi":"10.21474/ijar01/18303","DOIUrl":"https://doi.org/10.21474/ijar01/18303","url":null,"abstract":"Objective: To evaluate the thickness of pulp chamber and morphologic characteristics in order to plan the treatment ofdeciduous molars using cone beam computed tomography. Material and Methods: Cross-Sectional study is done with CBCT images of primary teeth of children. Evaluation of Pulp chamber thickness and morphology of each maxillary right primary second molar was done through CBCT. Data were analyzed and sent for statistical analysis. Results: Total 50 teeth i.e., right maxillary primary second molars of children age group 4-10 years were analyzed. Male shows the horizontal and vertical Mean (SD) values 4.5 (0.76) and 1.7(0.58) respectively greater than females. Mesial and Distal pulp horns were also greater in height for males with Mean (SD) 3.1(0.51) and 2.5(0.52) respectively. Conclusion:General variations might be involved however, when preparing a course of treatment for a childit is important to take note of gender differences in the mesiobuccal pulp horn. Even small restorations have a significant effect on pulp size. Probably it becomes exposed when the cavity is being prepared.","PeriodicalId":13781,"journal":{"name":"International Journal of Advanced Research","volume":"6 4","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-02-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140412650","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"ELEMENTS OF QUALITY PRESENT IN THE CURRICULAR DESIGN OF THE TECHNICAL PROGRAMS OF THE SCHOOL OF ADMINISTRATION OF THE NATIONAL UNIVERSITY OF COSTA RICA","authors":"Steve Ali Monge Poltronieri","doi":"10.21474/ijar01/18294","DOIUrl":"https://doi.org/10.21474/ijar01/18294","url":null,"abstract":"Todays education requires an important adaptation to the social and economic changes that surround it. Therefore, actions must be developed in conjunction with the different social actors to allow the design of educational programs with a more focused vision on local territories and that address the needs of specific populations, encouraging discussion and construction of the knowledge, as well as the possibility of increasing opportunities. The current research examines the quality components that are present in the curricular design of professional technical education and training programs in the School of Administration. A phenomenological technique with a qualitative approach was used to determine the presence of elements of educational quality, components of the curricular design used and the connection of the technical programs with current standards. It has been concluded that these technical programs incorporate quality elements in their curricular design.","PeriodicalId":13781,"journal":{"name":"International Journal of Advanced Research","volume":"2003 11","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-02-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140416493","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"DISSEMINATED TUBERCULOSIS PRESENTING AS AN ACUTE ABDOMEN","authors":"Akash Pawar, Vaibhav Yadav, Rahul Dubepuria, MD Yunus, Amit Priyadarshi","doi":"10.21474/ijar01/18284","DOIUrl":"https://doi.org/10.21474/ijar01/18284","url":null,"abstract":"Mycobacterium tuberculosis is a widespread infection in developing countries like India. Tuberculosis is primarily a chronic condition but can present with acute and unusual manifestations. Disseminated tuberculosis is defined as having two or more non-contiguous sites resulting from lymphohematogenous dissemination of mycobacterium tuberculosis ex.: Miliary TB. Before COVID-19, tuberculosis was the worlds leading cause of death due to a single infectious agent. Especially in India because India accounts for one-quarter of the global burden and prevalence, the incidence rate of Latent TB Infection (LTBI) and active tuberculosis is 33% & 36% respectively in India which is quite high, therefore it is important to consider tuberculosis as an etiological agent if symptom indicates and subsequent work up consideration. Here we are reporting a rare presentation of disseminated tuberculosis in an emergency department at a tertiary care center with sub-acute intestinal obstruction to emphasize the importance of clinical examination and history to evaluate for the cause, for the management of patients even in acute settings like emergency.","PeriodicalId":13781,"journal":{"name":"International Journal of Advanced Research","volume":"2000 17","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-02-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140416789","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"LA MICROFINANCE VERTE : VERS UNE INTEGRATION DU DISCOURS DE TRIPLE PERFORMANCE PAR LES INSTITUTIONS DE MICROFINANCE CONGOLAISES","authors":"Dede Aliango Marachto, Princia Ntumba Baruani","doi":"10.21474/ijar01/18345","DOIUrl":"https://doi.org/10.21474/ijar01/18345","url":null,"abstract":"La microfinance sest proposee comme une alternative aux systemes financiers traditionnels qui ne servent pas les populations a faibles revenus, les considerant comme trop risquees et non viables, en proposant a cette niche de la population des produits et services financiers adaptes a leur realite economique. Cependant, leffectivite de cette potentialite est tributaire de la capacite des IMF a concilier leur triple objectif de resultat : inclure un maximum possible de personnes a faible revenu et renforcer leur resilience face aux risques environnementaux, tout en realisant de bonnes performances financieres. Ainsi, cette etude tente de comprendre si les IMF font face a un arbitrage entre les performances sociale et environnementale, et la performance financiere dune part, et la nature de la contribution de loffre des produits financiers verts sur leur performance financiere dautre part. En utilisant un panel de trois (3) IMF en RDC avec le modele de regression Ridge a effets aleatoires sur la periode allant de 2019 a 2022, les resultats demontrent que les IMF ne sont pas necessairement confrontees a un arbitrage entre les trois dimensions de leurs missions, et que loffre des produis financiers verts ameliore la performance financiere des IMF.","PeriodicalId":13781,"journal":{"name":"International Journal of Advanced Research","volume":"105 S1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-02-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140411096","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"USING OF CUPPING TECHNIQUE AS A THERAPEUTIC MODEL IN TREATMENT OF NON-DISCOGENIC LOW BACK PAIN","authors":"Al-Sayed Mohamed Ahmed Almarakby","doi":"10.21474/ijar01/18285","DOIUrl":"https://doi.org/10.21474/ijar01/18285","url":null,"abstract":"Background: Cupping therapy is one of the traditional medical technologies practiced for thousands of years. it might have some additional benefits on early rehabilitation for post-stroke complications. Aim of the work: to examine if the use of cupping technique as a therapeutic model in treatment of discogenic low back pain has a significant impact or not. Methodology: 60 Patients divided into two equal groups were participated in this study: Group 1 treated by conventional post-stroke therapy and Group 2 treated by wet cupping in addition to conventional post-stroke therapy. The national institute of health stroke scale (NIHSS) index was sed as patients assessment tool for neurologic deficit evaluation motor functions is assessed by the Fugl-Meyer assessment (FMA) scale, the healing process depended on the bedside swallowing assessment (BSA). For cognitive function, the mini-mental state examination (MMSE) and Montreal cognitive assessment (MoCA) have been used, and any undesirable effect of wet cupping were noted for safety evaluation. Results: Better results have been documented with wet cupping therapy. Statistically significant improvement in pain reduction for both techniques of cupping (dry & wet) when compared to conventional medical therapy without augmentation with cupping therapy. Conclusion:Significant Effect of Hijama (Wet cupping) in post-stroke rehabilitation.","PeriodicalId":13781,"journal":{"name":"International Journal of Advanced Research","volume":"113 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-02-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140415561","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}