International Journal of Bioassays最新文献_第8页

Erythema induratum: a rare case with unusual presentation 顽固性红斑:罕见病例，表现不寻常

International Journal of Bioassays Pub Date : 2017-03-01 DOI: 10.21746/ijbio.2017.03.006

V. Naik, Hoogar Mb, Atul K. Jain, R. Dhar, Avni Gupta, Deesha Bhemat, P. Lad

{"title":"Erythema induratum: a rare case with unusual presentation","authors":"V. Naik, Hoogar Mb, Atul K. Jain, R. Dhar, Avni Gupta, Deesha Bhemat, P. Lad","doi":"10.21746/ijbio.2017.03.006","DOIUrl":"https://doi.org/10.21746/ijbio.2017.03.006","url":null,"abstract":"Tuberculosis, still one of the most common infectious diseases globally, manifests primarily as pulmonary tuberculosis. Extra-pulmonary tuberculosis can occur in other sites including skin. Cutaneous tuberculosis, comprising merely 1-2% of all forms of tuberculosis, has been classified into various morphological variants. One of the morphological variants of cutaneous tuberculosis is erythema induratum, a tuberculid, which is caused by hematogenous spread of tuberculosis, the pathogenesis of which is due to hypersensitive reaction against the mycobacterial antigens. The skin biopsy findings of erythema induratum are characterized by panniculitis with formation of non-caseating epithelioid granulomas with no mycobacteria detected in the lesions, though mycobacterial antigens or DNA could be detected by polymerase chain reaction (PCR). In this context, being presented here is a case of erythema induratum which is rare and unusual in its presentation inasmuch as caseating epithelioid granulomas were seen in the lesional skin biopsy along with detection of acid-fast bacilli. In our study a 57-year-old male presented to the Dermatology OPD with multiple erythematous lesions bilaterally over the groin and thigh regions. Clinically the lesions were considered to be equivocally suggestive of migratory erythema or erythema marginatum. The skin biopsy taken from the lesions revealed multiple epithelioid granulomas in the dermis with central areas of caseation necrosis. Sections stained with Ziehl-Neelsen stain showed the presence of occasional acid-fast bacilli. Erythema induratum, a rare tuberculid form of cutaneous tuberculosis, which is pathogenetically considered to be occurring as a result of hypersensitivity reaction against mycobacterial antigens with characteristic absence of tubercle bacilli. In the case presented here erythema induratum presents in a rare unusual manner as a caseating granulomatous lesion with presence of demonstrable acid-fast bacilli.","PeriodicalId":13765,"journal":{"name":"International Journal of Bioassays","volume":"15 1","pages":"5313-5316"},"PeriodicalIF":0.0,"publicationDate":"2017-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"91515868","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 3

Prevalence of malnutrition among children 0-5 years in rural area of Shamirpet, Ranga Reddy, India. 印度兰加雷迪沙米尔佩特农村地区0-5岁儿童营养不良发生率。

International Journal of Bioassays Pub Date : 2017-03-01 DOI: 10.21746/IJBIO.2017.03.008

Pavani Varma Mudunuru*, Prasad S. V.

引用次数: 1

Formulation and evaluation of sustained release saxagliptin microspheres by ionotropic gelation method 疏离子凝胶法制备沙格列汀缓释微球及评价

International Journal of Bioassays Pub Date : 2017-03-01 DOI: 10.21746/IJBIO.2017.03.0010

Madhurilatha Thadanki

{"title":"Formulation and evaluation of sustained release saxagliptin microspheres by ionotropic gelation method","authors":"Madhurilatha Thadanki","doi":"10.21746/IJBIO.2017.03.0010","DOIUrl":"https://doi.org/10.21746/IJBIO.2017.03.0010","url":null,"abstract":"The objective of the current investigation is to reduce dosing frequency and improve patient compliance by designing and systematically evaluating sustained release microspheres of an antidiabetic agent, saxagliptin. Saxagliptin microspheres were formulated using sodium alginate as the controlled release polymer by ionotropic gelation technique. The polymer sodium alginate alone and along with different coating polymers like pectin, ethyl cellulose was used in different ratios (1:1,1:1.5, 1:2) to formulate batches F1 to F9. The resulting microspheres were evaluated for particle size, densities, flow properties, morphology, recovery yield, drug content, drug entrapment efficiency and in vitro drug release behavior. The formulated microspheres were discrete, spherical with relatively smooth surface, and with good flow properties. The drug entrapment efficiency obtained in the range 70.4% to 95.2%. Among different formulations, the fabricated microspheres of batch F3 had shown the optimum percent drug encapsulation of microspheres and the sustained release of the saxagliptin for about 9 h. In vitro study showed that drug release slowly increases as the pH of the medium is increased. Release pattern of saxagliptin from microspheres of batch F3 followed Higuchi model and zero-order release kinetic model. The value of ‘n’ was found to be 0.867. The data obtained thus suggest that a microparticulate system can be successfully designed for sustained delivery of saxagliptin and to improve dosage form characteristics for easy formulation .","PeriodicalId":13765,"journal":{"name":"International Journal of Bioassays","volume":"24 1","pages":"5328-5333"},"PeriodicalIF":0.0,"publicationDate":"2017-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"76797580","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 6

Effect of media pH on the growth of entomopathogenic fungi isolated from different rhizosphere soils 培养基pH对不同根际土壤分离的昆虫病原真菌生长的影响

International Journal of Bioassays Pub Date : 2017-03-01 DOI: 10.21746/ijbio.2017.03.009

K. Teja

引用次数: 6

Survey for the powdery mildew of black gram [Vigna mungo (L.) Hepper] in parts of Northern Karnataka, India. 黑革螨白粉病的调查[j]印度卡纳塔克邦北部的部分地区。

International Journal of Bioassays Pub Date : 2017-03-01 DOI: 10.21746/IJBIO.2017.03.005

T. S. Channaveeresh, S. Kulkarni

引用次数: 1

Spatial - temporal analysis and potential health effects of air temperature - a case study in Makkah, Saudi Arabia. 气温的时空分析和潜在健康影响——以沙特阿拉伯麦加为例。

International Journal of Bioassays Pub Date : 2016-12-31 DOI: 10.21746/IJBIO.2017.01.002

T. Habeebullah

{"title":"Spatial - temporal analysis and potential health effects of air temperature - a case study in Makkah, Saudi Arabia.","authors":"T. Habeebullah","doi":"10.21746/IJBIO.2017.01.002","DOIUrl":"https://doi.org/10.21746/IJBIO.2017.01.002","url":null,"abstract":"High air temperature can adversely affect human health in various ways, including heat exhaustion and heat stroke. This paper analyses the spatial and temporal variability of air temperature within Makkah using data from 8 monitoring stations from 2002 to 2014. It was observed that air temperature varied both in space and time within Makkah and annual average temperature ranged from about 27 o C to 32 o C, however hourly temperature was much higher and reached as high as 55 o C, which is above the comfortable temperature range for most people, especially for elderly, women, children and those with chronic health problems. Spatial analysis showed that northeast region of Makkah experienced lower temperature, probably due to higher altitude. During the Study period, temperature demonstrated positive non-significant trends at most of the monitoring stations, except at Arafat and Abidiah where the trend was negative. Only Leeth monitoring station, representing Waly Al-Ahd area had positive significant trend. The positive trend is expected due to global warming and increasing urbanisation in this region, however the negative trend in Arafat and adjacent areas is most probably due to mass plantations of neem trees. Analysis shows that Hajj is moving towards hotter months (June, July and August) of the year, which might be a challenge for organisers of the Hajj as well as for the Pilgrims. Therefore, there might be a need for better planning during the coming years, including better housing, scheduling, transportation and ensuring the availability of better quality food and drinks.","PeriodicalId":13765,"journal":{"name":"International Journal of Bioassays","volume":"36 1","pages":"5196-5203"},"PeriodicalIF":0.0,"publicationDate":"2016-12-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"91183569","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 1

Resoluteness of biogas potential of Cr, Pb & Cd accumulated green algae Spirogyra sp. and Oscillatoria sp. 积累Cr、Pb、Cd的绿藻Spirogyra sp.和Oscillatoria sp.沼气潜力的分辨率。

International Journal of Bioassays Pub Date : 2016-12-31 DOI: 10.21746/IJBIO.2017.01.008

N. Brahmbhatt, R. Jasrai, Rinku V. Patel

{"title":"Resoluteness of biogas potential of Cr, Pb & Cd accumulated green algae Spirogyra sp. and Oscillatoria sp.","authors":"N. Brahmbhatt, R. Jasrai, Rinku V. Patel","doi":"10.21746/IJBIO.2017.01.008","DOIUrl":"https://doi.org/10.21746/IJBIO.2017.01.008","url":null,"abstract":"Water pollution due to heavy metals are spreading world-wide along with industrial progress. In this research work cultivation of Spirogyra sp . & Oscillatoria sp . were done and wastewater treatment of heavy metal such as Cr, Cd & Pb was accumulated by algae. After treatment of algae Spirogyra sp. & Oscillatoria sp. were decomposed and to prepare compost. The production of biogas from algal biomass becomes economically feasible and cheaper. This present study revealed that the nutrient content of natural compost was recorded about C- 38.5%, N- 3.31%, P- 1.02%, & K- 3.42%, heavy metal content of Cd- BDL, Pb- 0.21ml/mg & Cr- 0.01ml/mg and biogas value 19.19 l/kg. The maximum value of biogas was recorded at 30 ppm concentration (27.95 l/kg) of algal compost as compare to natural compost (19.19 l/kg) in Spirogyra sp . The experimental study concluded that the selected algae showed better biogas production as compared to natural. Whereas out of selected two algae, Spirogyra sp . gave better outcome as compare to Oscillatoria sp . Thus, Study suggested that algal biomass constitute a promising, efficient, cheap, decayed material for making compost and biogas production.","PeriodicalId":13765,"journal":{"name":"International Journal of Bioassays","volume":"79 1","pages":"5224-5229"},"PeriodicalIF":0.0,"publicationDate":"2016-12-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"83927745","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 1

Response to Cadmium stress in Vigna radiata L., Trigonella foenum-graceum L., Oryza sativa L. and Pennisetum glaucum L. 辐射荆芥、三角Trigonella foenum-graceum、水稻和狼尾草对镉胁迫的响应

International Journal of Bioassays Pub Date : 2016-12-31 DOI: 10.21746/IJBIO.2017.01.001

P. Menon, N. Joshi, A. Joshi

{"title":"Response to Cadmium stress in Vigna radiata L., Trigonella foenum-graceum L., Oryza sativa L. and Pennisetum glaucum L.","authors":"P. Menon, N. Joshi, A. Joshi","doi":"10.21746/IJBIO.2017.01.001","DOIUrl":"https://doi.org/10.21746/IJBIO.2017.01.001","url":null,"abstract":"Industrialization has resulted in the heavy metal contamination of agricultural soil. In the recent past, extensive studies on heavy metals are being carried out throughout the world, to understand the disturbances caused in the ecosystems. In the present study, Cadmium was assessed for its injurious effect on seed germination and seedling growth of Vignaradiata L., Trigonella foenum-graceum L., Oryzasativa L. and Pennisetumglaucum L. The seeds growing in petri dishes were exposed to cadmium in increasing concentrations of 1,3,5,10,50,100,200,300,500 ppm. Each treatment was replicated in a randomised design and observed over a period of 7 days. The seedlings were studied for their response based on germination rate, seed, vigour index, length of radicle, length of plumule and fresh weight against seeds germinated using distilled water as control. The intensity of inhibitory effect on all other parameters was directly proportional to the concentration of cadmium solution employed and inhibition was prominent from 50 ppm onwards. Based on the overall health of the seedling, the observed toxic effect of Cadmium was pronounced in Trigonella foenum-graceum L. > Oryza sativa L. > Pennisetum glaucum L. > Vigna radiate L.","PeriodicalId":13765,"journal":{"name":"International Journal of Bioassays","volume":"81 1","pages":"5192-5195"},"PeriodicalIF":0.0,"publicationDate":"2016-12-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"91223834","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

A study to assess the physical health status of children aged between 6-12 years in selected orphanages of Udupi district during 2008 to 2010 2008年至2010年期间评估乌杜皮区选定孤儿院6-12岁儿童身体健康状况的研究

International Journal of Bioassays Pub Date : 2016-12-31 DOI: 10.21746/IJBIO.2017.01.006

Ashly Elizabeth Emmanuel, S. Maheswari

{"title":"A study to assess the physical health status of children aged between 6-12 years in selected orphanages of Udupi district during 2008 to 2010","authors":"Ashly Elizabeth Emmanuel, S. Maheswari","doi":"10.21746/IJBIO.2017.01.006","DOIUrl":"https://doi.org/10.21746/IJBIO.2017.01.006","url":null,"abstract":"Children are placed in orphanages due to poverty, abandonment, illness, death of parents, severe familial dysfunction and so on. Any of those conditions can result in a multitude of health problems in a child. The main Objectives of the study were to assess the physical health status of children aged between 6-12 years in selected orphanages of Udupi district and to find out association between the physical health status and selected demographic variables. Descriptive research design was adopted for the study. An observational checklist on physical health status was developed to collect the data by using purposive sampling technique. The findings of the results showed that the majority (65%) of the children had poor physical health status whereas 35% of the children had good physical health status. The major prevalent morbid conditions among children were Bitot’s spot (65%), pale conjunctiva (65%), acute respiratory tract infection (81.7%), dental caries (88.3%), inflammation of tonsils (73.3%), lice in the head (53.3%), scabies (65%), ring worm infection (46.7%), pyoderma (23.3%). The assessment of nutritional status revealed that majority (60%) of the children had malnutrition.","PeriodicalId":13765,"journal":{"name":"International Journal of Bioassays","volume":"40 1","pages":"5214-5217"},"PeriodicalIF":0.0,"publicationDate":"2016-12-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"76903619","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 3

Inhibitory activity of Acetylcholinesterase (AChE) and Antioxidant activity of methanolic extract of Desmodium gangeticum (L.) 铁蒺藜甲醇提取物乙酰胆碱酯酶抑制活性及抗氧化活性的研究

International Journal of Bioassays Pub Date : 2016-12-31 DOI: 10.21746/IJBIO.2017.01.004

N. Ranjan, M. Kumari

引用次数: 1