International Journal of Bioassays最新文献

{"title":"International Journal of Bioassays Accomplishment: Achievement: Eventual","authors":"V. Wiwanitkit","doi":"10.14303/IJBIO.2020.9.1.2","DOIUrl":"https://doi.org/10.14303/IJBIO.2020.9.1.2","url":null,"abstract":"We would please to announce that International Journal of Bioassays is one of the most reputed journals known for its supportive association with scientific societies and researchers engaged in biochemical analytic research. Established in the year 2012  and  has been publishing the most recent developments in the fields of Biological, Chemical, Pharmaceutical and Medical Sciences, Biomedical Engineering, Bio- and Tribo-Corrosion, BioChip, Biomarkers & Diagnosis, Stimulus, Actinomycetes, Antibacterial, Antibacterial activity, Antimicrobial activity, DPPH, Diabetes Mellitus, Diversity, ELISA, Feeding habits, HPLC, LC-MS/MS, Oxidative stress, Prevalence, Psoriasis, Traditional knowledge as full length original Research Articles (RA), Review Articles (RevArt), Short Communications (SC), Case Studies (CS) and Letters To Editor (LTE).","PeriodicalId":13765,"journal":{"name":"International Journal of Bioassays","volume":"33 1","pages":"5761-5761"},"PeriodicalIF":0.0,"publicationDate":"2020-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"73728527","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Comparison Between Real and Label Content of Different Bottled Water Brands From Saudi Arabia and Other Countries","authors":"A. Dablool","doi":"10.14303/IJBIO.2020.9.1.1","DOIUrl":"https://doi.org/10.14303/IJBIO.2020.9.1.1","url":null,"abstract":"Bottled water is consumed in many countries of the world to access safe and clean water. Good drinking-water quality of bottled water has high importance for human health, and standards for drinking-water quality have been defined by World Health Organization (WHO) and GCC Standardization Organization (GSO). Deviations from these standards may cause mild to severe health constraints. For consumers, the water composition is indicated on a label attached to the water bottle. Reports about wrong label information were the motivation for a large study of the real content of 20 different bottled water brands from Saudi Arabia in comparison with 19 brands from different countries in Asia, Oceania, Africa, and Europe. The pH, total dissolved salt (TDS) concentration, and concentrations of nine cations and anions are measured to determine for all Saudi and international brands that the water content is conform with the standards for drinking-water quality, confirming that bottled water from all tested brands is safe for consumption. Furthermore, this measured real content agrees for most tested brands with the water content indicated on the bottle labels, proving the labels’ reliability. Statistical analysis also reveals that the drinking-water quality of the Saudi brands is comparable to that of the international brands. Considering the increase in consumption of bottled water, especially in geographic areas where no tap water of drinking-water quality is available, quality control of bottled water becomes essential, aiming for correct information on the bottle label to reliably inform consumers and ensure human health.","PeriodicalId":13765,"journal":{"name":"International Journal of Bioassays","volume":"31 1","pages":"5755-5762"},"PeriodicalIF":0.0,"publicationDate":"2020-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"84675940","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Heterosis and combining ability in bitter gourd (Momordica charantia L.)","authors":"Acharya Sk, K. Ra, Ameta Kd, D. Rb, B. Upadhyay","doi":"10.14303/ijbio.2019.8.1.3","DOIUrl":"https://doi.org/10.14303/ijbio.2019.8.1.3","url":null,"abstract":"Ten parents of bitter gourd viz., Solan Hara, Pusa Do-Mousmi, BG-14, Green Long, MDU-1, IC-85605, IC-45346, IC-68272-1, IC-68237 and Solan Collection and their forty five crosses (using half diallelic system) along with check viz., Jhalri, US-6214 and US-6203 were evaluated in field trials in two locations Udaipur and Chittaurgarh in two different seasons which consists four environments. Economical heterobeltiosis for yield per vine (kg) were recorded in IC 85605 x IC 45346 (38.94%) and MDU 1 x IC 85605 (34.98%) over the environments. Good general combiners for various economic traits IC-68237 for number of primary branches per vine (0.09), fruit length (0.52), fruit diameter (0.17) & number of fruits per vine (0.22) over the pooled environments. SCA (Specific Combining Ability) for economic traits were observed in Solan Collection x IC 68237 (1.24) for number of fruits per vine, IC 68237 x MDU-1 for fruit length (1.82) and fruit weight (7.81). These results indicate that both additive and non-additive gene effects are involved in the inheritance of the studied traits. The additive gene action was more important than the non-additive ones in the genetics of most studied traits.","PeriodicalId":13765,"journal":{"name":"International Journal of Bioassays","volume":"2 1","pages":"5692-5711"},"PeriodicalIF":0.0,"publicationDate":"2019-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"86993371","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Halophytes of Thar Desert: Potential source of nutrition and feedstuff","authors":"A. Joshi, Bhanupriya Kanthaliya, Jaya Arora","doi":"10.14303/IJBIO.2019.8.1.1","DOIUrl":"https://doi.org/10.14303/IJBIO.2019.8.1.1","url":null,"abstract":"Salinity associated with drought is severe ecological threat in the Western part of Rajasthan which is recognized as “Thar Desert’’. The increased population and the deterioration of the arable lands make it inevitable to exploit marginal and long-neglected natural resources and re-assess them in the provision for utilization. Halophyte plants are widely distributed throughout several regions of the Western part due to the presence of saline extents such as Pachpadra, Lunkarsar, Khajuwala, Lanela as well as Thob. The growth of salt-tolerant fodder species for animals and other livestock offers a major opportunity to use land and water resources that are too saline for conventional crops and forages. To illustrate this point, we conducted literature searches regarding growth, biomass production and nutritive value of halophyte plants under saline irrigations practice throughout the world. This review summarized the valuable information regarding the perspective of wild halophytes as promising foodstuff alternative for animal raised in saline lands and or in arid and semi-arid regions. To sum up, it seems that a wide range of halophytes (Haloxylon spp., Suaeda spp., Trianthema spp., Zygophyllum spp.) and salt-tolerant grasses (Juncus spp., Sporobolus spp) could be considered as promising feed resources for cattle and other livestock raised in the Thar Desert. However, further research is needed regarding the chemical characterizations of these plants under commercial cultivation practices and their long-term bioactivity with safe consumption.","PeriodicalId":13765,"journal":{"name":"International Journal of Bioassays","volume":"35 1 1","pages":"5674-5683"},"PeriodicalIF":0.0,"publicationDate":"2019-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"81191284","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Implementation of Principles of Pharmaco-economics and Pharmacovigilance to Achieve Optimal Financial and Therapeutic Benefits through WHO- Essential Medicine Policy","authors":"S. Saravdekar","doi":"10.14303/IJBIO.2019.8.1.2","DOIUrl":"https://doi.org/10.14303/IJBIO.2019.8.1.2","url":null,"abstract":"It is evident and revealed by the experience of State of Maharashtra during 2007-2011, that the Effective Application of principles of pharmaco-economics & pharmacovigilance in Medication Management, not only gives assurance about the all-time availability and quality of essential medicines but also saves substantial amount of government exchequer, by procuring the Assured Quality Generic Medicines at most economic rates. These policies were based on following principles of Pharmaco-economic: 1. Selection of Generic Medicines based on W.H.O. Essential List of Medicines. 2. Pooling of need of medicines of all state run hospitals at state level to obtain lowest rates through economies of scale. 3. Selection of “Quality Assured Generic Medicines-through Pre-Qualification conditions. 4. Selection of multiple suppliers per medicine to improve all time availability of essential medicines. 5. Reducing expenditure and workload of procurement, storage and inventory of medicines. 6. Curtailing wastage of funds on procurement of non-essential medicines. Pharmacovigilance-The policy of limited number of essential medicines had been further helped in improving the health care services in the state of Maharashtra, by: 1. Promoting Ethical & Rational use of medicines at physicians, nurses & pharmacists level through publication of “State Hospital Formulary”. 2. Protecting the health of patients from use of harmful effects of non-essential medicines & irrational Fixed Dose Combinations (FDCs). 3. Improving patient compliance to the therapy by patients through establishment of “Patient Counseling Centers” at Out Patient Departments in the hospitals and by optimal utilization of pharmacy services. The overall boost in the Image of public healthcare services–The availability of quality assured generic medicines, had gained the confidence of physicians, and had reduced the expenditure on hospital stay of the patients because of fast recovery. And all these benefits together had boosted overall image of the hospital in the society.","PeriodicalId":13765,"journal":{"name":"International Journal of Bioassays","volume":"1 1","pages":"5684-5691"},"PeriodicalIF":0.0,"publicationDate":"2019-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"80225214","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Effects of Lead Chloride on Growth Performance of Clarias gariepinus (Burchell, 1822)","authors":"Oluwatosin E. Ayegbusi, O. Aladesanmi, Oluwasaanu E. Kosemani, O. Adewusi","doi":"10.21746/ijbio.2018.7.5.2","DOIUrl":"https://doi.org/10.21746/ijbio.2018.7.5.2","url":null,"abstract":"The study determined the median Lethal Concentration (LC50), investigated the growth and behavioral response of Clarias gariepinus to sub-lethal concentration of lead chloride in a static renewal bioassay. Acute toxicity test was carried out using different concentrations of lead (350, 400, 450, 500, 550 mg/L) in a statics bioassay for 96 hrs to assess median lethal concentration of lead on the fish. The concentrations used for the sub-chronic toxicity test were based on the results obtained from the acute test. A static renewal bioassay procedure was adopted in which the test culture was regularly renewed every 48 hrs at the set concentrations of PbCl2 (0, 20, 40, 60, 80, 100, mg L−1). The growth and behavioral response and as well as the mortality response were monitored for the 21 days of exposure. Data obtained were analysed using Analysis of Variance (ANOVA). The results showed an LC50 of 426 mg/L. Sublethal exposure showed a decrease in growth rate with an increase in PbCl2 concentration. The value of specific growth rate (1.95 ± 0.015 mg/L) of fish in the control tank was significantly (p<0.05) higher than the other level of PbCl2 concentrations. The fish behavior was normal through-out the period of experiment (21 days) with some exceptions where there was erratic movement in high concentration (80 mg/L and 100 mg/L), lethargy and vertical positioning majorly after 48 hrs prior to changing of the water. The study concluded that lead metal (heavy metal) has negatively impacted on Clarias gariepinus with a reduction on growth performances and behavioral response.","PeriodicalId":13765,"journal":{"name":"International Journal of Bioassays","volume":"34 1","pages":"5638-5644"},"PeriodicalIF":0.0,"publicationDate":"2018-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"84289492","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Ossa wormiana-A morphological study","authors":"Rani Nallathamby, Meril Ann Soman","doi":"10.21746/ijbio.2018.7.6.4","DOIUrl":"https://doi.org/10.21746/ijbio.2018.7.6.4","url":null,"abstract":"Goethe’s osscicles or Wormian bones are islands of small bone tissue that were accidentally intercalated in the cranium sutures which were formed out of additional ossification centers which had no relation with the regular ones. These bone tissues are studied by various researchers who succeeded in associating them with various central nervous system disorders, acknowledging their presence to be important in the fields of neurosurgery, radiology and anthropology.","PeriodicalId":13765,"journal":{"name":"International Journal of Bioassays","volume":"41 1","pages":"68-72"},"PeriodicalIF":0.0,"publicationDate":"2018-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"83001581","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"A survey on home generated medical wastes during Hajj event","authors":"A. F. Alsebaei","doi":"10.21746/IJBIO.2018.7.3.1","DOIUrl":"https://doi.org/10.21746/IJBIO.2018.7.3.1","url":null,"abstract":"Medical waste is mainly generated from activities at health care facilities, but may also be generated at homes and crowded communities such as Hajj event (pilgrimage). In these cases, they would become harmful and threaten the health of pilgrims and visitors. The study was carried out to evaluate the knowledge, attitude, practice regarding home generated medical wastes among pilgrims and to estimate the prevalence of the most common types of these hazardous wastes during Hajj event in pilgrims’ hotels. Questionnaire survey was conducted using a cross sectional design among a random sample population and the respondents were questioned about the types of medical waste they had generated. About 56% of the respondents had low knowledge about any awareness program related to home generated medical waste while 73.7% of them had positive attitude and were ready to respond to the any orientation or educational program regarding medical waste management. The answers of participants were varied regarding their hygienic practice towards medical wastes depending on the type of the medical waste; masks, bandages, residues of medicines and needles with ratio of 65.5%, 61.2%, 58.1% and 51.4%, respectively. The total home generated medical wastes during Hajj event were estimated to be 155.1 tons with a ratio of 14.1 tons/day and 6 g/pilgrim/day. Of these wastes, 42.3% were gloves, 16.6% were masks, 8.9% were medicines residues and 7.3% were gauze. The most common medicine residues were found to be glucose bottles (12.5%) and IV fluids (11.6%). It was concluded that Hajj pilgrims had positive attitude to respond to the any orientation program. The rate of generation of home solid medical waste generated during Hajj is estimated to be high; therefore it is recommended that community awareness initiatives, educational and proper training programs should be launched among housekeepers and the residents of hotels and buildings on the safe methods of disposal of home generated medical wastes during seasons.","PeriodicalId":13765,"journal":{"name":"International Journal of Bioassays","volume":"48 1","pages":"5606-5611"},"PeriodicalIF":0.0,"publicationDate":"2018-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"91165609","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Chemical constituents and antimicrobial activity of the leaf essential oil of Ixora coccinea L (Rubiaceae) collected from North Central Nigeria","authors":"Samuel Ehiabhi Okhale, Grace E. Ugbabe, P. Oladosu, J. Ibrahim, H. Egharevba, O. Kunle, Elisha Ep, Chibuike Aj, Ettah Uo","doi":"10.21746/ijbio.2018.7.5.1","DOIUrl":"https://doi.org/10.21746/ijbio.2018.7.5.1","url":null,"abstract":"Essential oils have found vast applications in many fields including aromatherapy, flavor and fragrance industries. Ixora coccinea Linn. is a reputable medicinal plant with long history of use in Nigeria. This study aimed to investigate the chemical constituents and antimicrobial activity of the leaf Essential Oil (EO) of Ixora coccinea grown in Nigeria. EO was obtained by hydrodistillation with yield of 0.16% (w/w). Chemical constituents of EO were determined using Gas Chromatography coupled to Mass Spectrometry (GC-MS). The GC-MS analysis identified 43 compounds, representing 94.67% of the oil constituents. The analysis revealed eight classes of compounds including hydrocarbons, alcohols, carboxylic acids, esters, aldehydes, ketones, sesquiterpenoids and triterpenoids. Hydrocarbons accounted for 33.77% with decane (11.12%) as the highest; alcohols comprised 28.86% of the oil with the highest being linalool (10.54%). Esters made up 14.15% of the oil. Carboxylic acid (10.91%) was dominated by malonic acid (10.26%); sesquiterpenoids made up 6.84% of the oil dominated by 3,7,11-trimethyl-1,6,10-dodecatrien-3-ol (3.07%). Aldehydes made up 3.36% of EO dominated by heptadecanal (2.30%). Ketones accounted for 1.38% of the oil. The inhibitory effect of EO was evaluated against Staphylococcus aureus, Pseudomonas aeruginosa, Escherichia coli, Candida albicans and Mycobacterium tuberculosis (BCG) using broth microdilution method. The essential oil showed significant antimicrobial effects against the test organisms, with Minimum Inhibitory Concentration (MIC) ranging from 50 to 200 I¼g/mL. This result showed that EO could serve as adjunct therapy in the treatment of community acquired infections.","PeriodicalId":13765,"journal":{"name":"International Journal of Bioassays","volume":"14 1","pages":"5630-5637"},"PeriodicalIF":0.0,"publicationDate":"2018-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"78432457","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Simultaneous Detection of Ofloxacin and Lomefloxacin in Milk byVisualized Microplate Array.","authors":"Zhoumin Li, Kaian Yaoa, Xinai Lia, Danke Xu","doi":"10.21746/IJBIO.2018.7.4.2","DOIUrl":"https://doi.org/10.21746/IJBIO.2018.7.4.2","url":null,"abstract":"A sensitive, simple, inexpensive, simultaneous analytical method for ofloxacin and lomefloxacin in milk by immunoassay without the need of time-consuming or complex pre-treatment steps was reported. A 96-well microplate was used as solid support, on which ofloxacin antigen and lomefloxacin antigen were immobilized, respectively. After immobilization, a mixture of relevant antibodies and standard solutions containing the analytes or samples were added to the array reaction area, then added silver nanoparticles (AgNPs) labeled secondary antibody. Silver enhancement technique was applied to amplify the detection signals, which produced black image on array spots visible with naked eyes. The signals were detected with a microarray scanner; therefore the analyte residues could detect quantitatively. The Limits of Detection (LOD) (3SD) were estimated to be 0.24 ng/mL (ofloxacin) and 0.35 ng/mL (lomefloxacin).","PeriodicalId":13765,"journal":{"name":"International Journal of Bioassays","volume":"8 1","pages":"5623-5629"},"PeriodicalIF":0.0,"publicationDate":"2018-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"89345195","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}