INTERNATIONAL JOURNAL OF APPLIED PHARMACEUTICAL SCIENCES AND RESEARCH最新文献

{"title":"AN INSIGHT INTO THE TREATMENT STRATEGIES OF OBESITY USING SEMAGLUTIDE AND ITS COMPETITIVE ANALOGUES: A REVIEW ARTICLE","authors":"Nahid Rao, Reenoo Jauhari, Vaishali Sati, Pallavi Godiyal","doi":"10.31069/japsr.v5i2.02","DOIUrl":"https://doi.org/10.31069/japsr.v5i2.02","url":null,"abstract":"Obesity is a major public health problem in the world. This growing rate represents an epidemic that requires immediate attention. Oral Semaglutide is a semaglutide compound with an absorption enhancer, a sodium N- (8 - [2-hydroxybenzoyl] amino) caprylate (SNAC). The mechanism of action simply produces Glucagon-like peptide-1 (GLP-1) as a food-based digestive hormone that acts as an appetite signal, stimulates insulin release, inhibits glucagon production, and regulates diarrhea. This article shows the correlation of GLP-1 association with motivation to feed and Semaglutide’s anorectic effect and relation to cravings. We have performed complete searches from PubMed, Cochrane, Scopus, Medline, Medscape, and Wiley online library from 2015 to 2022. The trial data (SUSTAIN, PIONEER, STEP) suggested a major decrease in weight and HbA 1c. SELECT trial data showed cardiovascular safety of semaglutide over other anti-diabetic drugs. This review article summarized semaglutide trial data as an anti-obesity drug and compared the effects of semaglutide (oral and subcutaneous) with other GLP-1 analogs.","PeriodicalId":13749,"journal":{"name":"INTERNATIONAL JOURNAL OF APPLIED PHARMACEUTICAL SCIENCES AND RESEARCH","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2022-09-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"84502167","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"MELATONIN: ROLE IN THE PROPHYLAXIS OF MIGRAINE","authors":"Vaishali Sati, Reenoo Jauhari, Nahid Rao, Pallavi Godiyal, Aseem Babbar","doi":"10.31069/japsr.v5i2.03","DOIUrl":"https://doi.org/10.31069/japsr.v5i2.03","url":null,"abstract":"Melatonin and migraine have been linked in most ways, from mechanisms to treatment. Migraine is one of the common neurological diseases and it is characterized by throbbing unilateral headache attacks. Migraine is an issue for both individuals and society. Migraine can lead to reduced work productivity and a flawed family and social life. It has been suggested that melatonin plays a key therapeutic role in treating migraines and several other types of headaches. Early and exact diagnosis is essential in enhancing treatment and in preventing progression. This review aimed to evaluate the available evidence related to the efficacy and safety of melatonin in the prophylaxis and prevention of migraine. Research in regard the administration of melatonin found it safe in migraine patients, with few or no side effects. This review concluded that Melatonin can be considered a safe integrative prophylactic treatment for children, adults and menstrual-related migraines, thus improving outcomes related to patient’s quality of life and patient-centered care. However, further studies and evaluation is required to confirm its effects.This review aimed to evaluate the available evidence related to the efficacy and safety of melatonin in migraine prophylaxis. Melatonin and migraine have been linked in a majority of ways, from mechanisms to treatment. Melatonin is an endogenous hormone and is secreted by the pineal gland. It plays an important role in regulating circadian rhythm and the sleep-wake cycle. It has been proposed for migraine prevention due to its anti-inflammatory effects against calcitonin gene-related peptides and other pro-inflammatory mediators in vitro, and its pro-regulatory effect on the circadian rhythm. Also, low melatonin levels have been reported in serum and urine due to hypothalamic dysfunction in patients with migraine. Hence, in this article, we review those papers describing the results of the administration of melatonin in humans for therapeutic purposes in treating migraines.This narrative literature review was based on studies on Melatonin's effectiveness, safety and tolerability for the prophylactic and preventive treatment of migraine in children and adolescents and menstruating women. The literature search was conducted using the Google Scholar and PubMed database and included articles published up to December 2021, utilizing the keywords: “melatonin”, “migraine”, “melatonin and migraine”, and “prophylaxis of migraine”. Observational studies, randomized controlled trials (RCTs), case reports and systematic reviews were included. The articles focusing on the latest medication for preventing migraines were also reviewed.","PeriodicalId":13749,"journal":{"name":"INTERNATIONAL JOURNAL OF APPLIED PHARMACEUTICAL SCIENCES AND RESEARCH","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2022-09-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"81626415","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"NANOEMULGEL BASED ON GUAR GUM AND PLURONIC® F127 CONTAINING ENCAPSULATED HESPERIDIN WITH ANTIOXIDANT POTENTIAL","authors":"Isadora Freitas De Sousa, L. Rebouças, C. D. G. Sampaio, N. Ricardo, E. M. A. Santos, Antônio Lucas Freitas Da Silva","doi":"10.31069/japsr.v5i2.04","DOIUrl":"https://doi.org/10.31069/japsr.v5i2.04","url":null,"abstract":"Introduction: The development of antioxidant cosmetic products based on natural products added to nanotechnology is gaining more and more prominence. However, some of these actives are hydrophobic, which makes their placement in aqueous systems impossible. As a strategy to deliver hydrophobic actives in hydrophilic gels, nanoemulgels have been presented. \u0000Materials and Methods: The present study aimed to prepare an aqueous nanoemulgel based on guar gum and Pluronic® F127 as a strategy for the delivery of hesperidin, a hydrophobic flavonoid. A nanoemulsion was prepared and characterized to be incorporated into the gel. The formed nanoemulgel was evaluated for rheology and antioxidant activity. \u0000Results and Discussion: The nanoemulsion had a particle size of 192 ± 4 nm, a polydispersity index of 0.11 ± 0.01 and a zeta potential of -32.1 ± 0.9 mV. The encapsulation efficiency obtained was 99.35% and the rheological study of the nanoemulgel showed satisfactory gel characteristics for topical use. The antioxidant potential of nanoemulsions by the DPPH method presented an IC50 value of 14.4 ±1.3 μg mL-1 expressed in hesperidin equivalent to 17.4 mg mL-1 of the nanoemulgel. The formulated nanoemulgel delivered hesperidinsuccessfully without affecting its antioxidant properties, showing promise as a cosmetic for topical anti-aging use.","PeriodicalId":13749,"journal":{"name":"INTERNATIONAL JOURNAL OF APPLIED PHARMACEUTICAL SCIENCES AND RESEARCH","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2022-09-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"86761146","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"IS ARTIFICIAL INTELLIGENCE VIZ M AND D LEARNING COULD BE THE SOLUTION PROMISING ALTERNATIVE TO ANIMALS: A LEARNING-BASED TOXICITY RECITATION?","authors":"R. Mishra, R. Kaushik, Ajay Shukla, Smriti Ojha, Sudhanshu Mishra, R. S. Dubey","doi":"10.31069/japsr.v5i2.01","DOIUrl":"https://doi.org/10.31069/japsr.v5i2.01","url":null,"abstract":"Similar to animal and human studies, the data show that when many animal models are extrapolated to humans, reliability is limited when it comes to predicting drug effects. This leads to an unbalanced waste of time and money and nightmares during drug development because the drug works well in animals or pre-clinical models and therefore fails in clinical studies or clinical trials, or vice versa. In this technique, machine and deep learning (M and D) is a subset of artificial intelligence. We hope this will eliminate the need for lengthy searches, reduce the number of animals sacrificed in the strategy, and reduce the cost and time required for testing. We recognize that full replacement of animals in toxicological or pre-clinical studies and tests remains a challenge - we acknowledge M and D learning-based animal toxicity prediction can be the key.","PeriodicalId":13749,"journal":{"name":"INTERNATIONAL JOURNAL OF APPLIED PHARMACEUTICAL SCIENCES AND RESEARCH","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2022-09-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"78252423","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"USE OF TAFENOQUINE IN ANTIMALARIAL TREATMENT: A LITERATURE REVIEW","authors":"Cristiane Tefé-Silva, Nathália Del Vecchio França Barbosa, A. Fernandes, Anne Kareninne Domingos de Matos, Giulia Eugenio Oliveira, Isabela Buck Miele, Isabella Monteneri Benassi Melo, Marcela Toledo Bortoletto, Maria Laura Correa Aneli, Yasmin Carolina Pereira","doi":"10.31069/japsr.v5i1.1","DOIUrl":"https://doi.org/10.31069/japsr.v5i1.1","url":null,"abstract":"Besides the intensification of control measures, Plasmodium vivax poses a major challenge for malaria elimination efforts. This type of malaria parasite causes a persistent liver stage where the liver suffers the action of the hypnozoites, a form of the P. vivax that is very relevant at this stage of the infection and causes relapse of the disease and continued transmission. This literature review discusses an innovative treatment for malaria with tafenoquine (TQ), an 8-aminoquinoline synthetic primaquine analog that has been used in one dose for malaria relapse prevention and for prophylaxis due to its longer half-life, and its effects on the human body. Besides the use of tafenoquine, it was also necessary to discuss the Glucose-6-phosphate dehydrogenase (G6PD) deficiency, and the interaction of this enzyme with the 8-aminoquinolines, since both drugs may induce hemolytic anemia in patients with G6PD deficiency; therefore, the test to this deficiency is necessary before putting those patients under treatment with these drugs. The use of other drugs combined with tafenoquine was also reported. The drugs Primaquine, chloroquine, and other analogs, such as artemisinin and hybrids, were discussed in this article, along with their combined use and their greater or lesser help in the treatment.","PeriodicalId":13749,"journal":{"name":"INTERNATIONAL JOURNAL OF APPLIED PHARMACEUTICAL SCIENCES AND RESEARCH","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2022-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"82308087","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"CHEMICAL COMPOSITION AND ANTIOXIDANT ACTIVITY OF THE ESSENTIAL OIL OF CHROMOLAENA ODORATA HARVESTED IN THE REGION OF THE MOUNTAIN DISTRICT OF CÔTE D'IVOIRE.","authors":"Seraphin N'DRI Konan, Yéo Sounta Oumar, T. Lanciné, Kouamé Bosson Antoine, Mamyrbékova-Békro Janat Akhanovna, B. Yves-Alain","doi":"10.31069/japsr.v5i1.4","DOIUrl":"https://doi.org/10.31069/japsr.v5i1.4","url":null,"abstract":"Introduction: The aromatic plants have occupied an important place in the daily life of man. The excessive and repetitive use of drugs has led the body to develop resistance to their curative effects. Many authors have focused on the study of the therapeutic properties of essential oils in order to provide new remedies. They are used as a source of bioactive molecules of natural origin. Objective: The objective of this work is to contribute to the valorization of medicinal and aromatic plants of the Ivorian flora. We propose to determine the chemical composition and to evaluate the antioxidant activity by spectrophotometry of the essential oil. Materials and Methods: The plant material consists of the leafy twigs of C. odorata. The technical of steam distillation using a four-compartment stainless steel device was used to extract the essential oil from the plant matrix. The analysis of the essential oils was carried out on a GC chromatograph (7890A, Agilent Technologies) coupled to a mass spectrometer (5975C, Agilent Technologies). The antioxidant potential of the extracts was evaluated using the Blois method. Results:  The essential oil obtained by steaming, with an aromatic odor and pale green color has a yield of (0.082 ± 0.004) %. Analysis of the chromatogram and mass spectra identified 24 phytocompounds (99.92%). The phytochemical composition is dominated by hydrocarbon sesquiterpenes (44.21%) followed by hydrocarbon monoterpenes (29.48%) and other compounds (26.23%). The major compound are α-pinene (17.79%), 6-propen-1-enylbicyclo [3.1.0] and hexan-2-one (14.95%) . Conclusion: The essential oil extract of  C. odorata exhibits low antioxidant activity compared to vitamin C.","PeriodicalId":13749,"journal":{"name":"INTERNATIONAL JOURNAL OF APPLIED PHARMACEUTICAL SCIENCES AND RESEARCH","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2022-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"75798093","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"MORTALITY AND MORBIDITY OF MEASLES FROM 21 MARCH 2021 TO 20 MARCH 2022 IN MIRWAIS REGIONAL HOSPITAL PEDIATRIC DEPARTMENT KANDAHAR AFGHANISTAN","authors":"Nik Mohammad Zafari, M. Forqani, Mir Ziaurahman Mehrabi","doi":"10.31069/japsr.v5i1.3","DOIUrl":"https://doi.org/10.31069/japsr.v5i1.3","url":null,"abstract":"Background: Objectives: To study the demographic profile and mortality and morbidity  of measles, as well as the outcome of the measles in children who were admitted to pediatric department of Mirwais regional Hospital, Kandahar Afghanistan from the 2021 to 2022. Methodology: This cross-sectional study was conducted in Mirwais Regional hospital pediatric ward Kandahar Afghanistan The diagnosis of measles based on clinical features, The data of all the patients of measles who were from 1month to 15 years, and  were admitted from measles in MRH in pediatric ward from 21 march 2021 to 20 March 2022, compiled and analyzed from the Medical Records of each case at Hospital. Information obtained from the medical record from each patient file and was coded and entered into computer software. After that, the data were analyzed with SPSS version 22. 0. Results: Total 16792 patients were admitted during the study period and among them 1865 were confirmed as measles. Average Rate of measles was found as 11.1% among hospitalized children. There were 1050 (56.30%) male patients and 815 (43.7%) female patients with a male female ratio of 1.28:1. Among the measles patients age of onset was <6 months in 38(2%), 6-12 months in 633(33.94%),13-60 months in 1028(55.12%) and 61-120 months 137(7.34%) and 29(1.55%) above in 120months .the majority of the measles children were in the age group between one year up to 5years old. Prevalence of measles during was 11.1 % in 2021 to 2022. Which has clearly high incidence in 2022 and with lower incidence of measles cases in 2021. case fatality among measles diagnosed children was 118(6.32%) in (2021 to 2022) which shows cleared increase in 2022. we also found in our study more cases were in spring and winter season N=(621-579),from  (2021 to 2022).Conclusion: The prevalence and case fatality of measles was higher   form one year to 5years of age. Although boys were more affected by measles than girls, Majority of measles cases developed in rural  than urban areas in 2021.","PeriodicalId":13749,"journal":{"name":"INTERNATIONAL JOURNAL OF APPLIED PHARMACEUTICAL SCIENCES AND RESEARCH","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2022-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"74970076","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"STUDY ON STUNTING OF 6 TO 59 MONTHS CHILDREN AND FACTORS ASSOCIATED WITHIN AT GARDEZ CITY, PAKTIA PROVINCE OF AFGHANISTAN","authors":"Mohammad Hanif Ahmadzai, Khoshal Janatzai, Maail K Mangal","doi":"10.31069/japsr.v5i1.5","DOIUrl":"https://doi.org/10.31069/japsr.v5i1.5","url":null,"abstract":"Introduction: Evidence about risk factors of Stunting is useful to design appropriate policies and strategies to control health problems. Objective: A cross-sectional study was conducted among children aged 6-59 months in Paktia Regional Hospital. Material and Methods: A total of 400 children were included in the study. Data were collected using a structured questionnaire and anthropometric measurement. The interview was conducted with parents/caretakers of the children to fill the questionnaire. SPSS version 25.0 statistical software was used for analysis. Cross tabulation and Logistic regression analyses were conducted to identify factors associated with the nutritional status of the children.  Results: Statistical association was declared significant if the p-value was less than 0.05.  The prevalence of Stunted was 41%. Variables; Gender, Family size, Number of children under 5, Life status of parents, Father's educational level, Mother's educational level, Annual income status, Food items do you feed to children, Awareness about weaning and supplementary food, Awareness about malnutrition, Age Weaning food should be started, Breast-feed status, period of time to feed breast, Food during Pregnancy, Status of immunity, Vaccinated during pregnancy, The age gap between babies and mothers' malnutrition (MUAC) status are statistically associated with Stunting. Height for age (stunted) is high among children aged 6–59 months in Gardez Town. Conclusion: Lack of awareness on malnutrition and child feeding, maternal nutrition status, family size, family income, and the age gap between babies are risk factors of malnutrition. Thus, therefore, the concerned bodies must design policies, which can improve the livelihood of households, works on information dissemination using mass media about malnutrition, weaning, and supplementary foods, and family planning and on meals during pregnancy.","PeriodicalId":13749,"journal":{"name":"INTERNATIONAL JOURNAL OF APPLIED PHARMACEUTICAL SCIENCES AND RESEARCH","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2022-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"81267702","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"A BRIEF REVIEW ABOUT PATIENT COUNSELLING","authors":"Tanya Rayal, Reenoo Jauhari, P. Roy, Jyoti Roy","doi":"10.31069/japsr.v5i1.2","DOIUrl":"https://doi.org/10.31069/japsr.v5i1.2","url":null,"abstract":"All around the world, the profession of pharmacy and the notion of pharmaceutical care are quickly evolving. In addition, the pharmacist's role in promoting logical and cautious use of medicine is becoming more important as a result of his technical and professional understanding. It is clearly known that patients who are adequately informed about medications and how to take them receive safe and effective treatment. Therapeutic pharmacists interact with patients on a frequent basis and assist with clinical treatments in addition to the numerous technical activities performed behind the counter. It is not enough to simply hand over a medicine kit to the patient or their representative; it is also necessary to hand over the correct drug to the correct person with the correct information. The act of assisting a client in seeing everything clearly, potentially from a different perspective. This might assist the client in focusing on feelings, experiences, or behaviour with the goal of achieving positive change and establishing a trusting connection. Confidentiality is essential for successful counselling.","PeriodicalId":13749,"journal":{"name":"INTERNATIONAL JOURNAL OF APPLIED PHARMACEUTICAL SCIENCES AND RESEARCH","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2022-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"82088362","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"HEPATOPROTECTIVE ACTIVITY OF CNIDOSCOLUS PHYLLACANTHUS LEAVES AGAINST D-GALACTOSAMINE INDUCED HEPATOTOXICITY IN RATS","authors":"Radhe Shyam Sharma, B. Tyagi, P. Chouhan","doi":"10.31069/japsr.v4i4.2","DOIUrl":"https://doi.org/10.31069/japsr.v4i4.2","url":null,"abstract":"Introduction: Plants have been utilized as a natural source of medicinal compounds for thousands of years. Humans use numerous plants and plant-derived products to cure and relieve various physical and mental illnesses. These plants are used in traditional Chinese, Ayurveda, Siddha, Unani, and Tibetan medicines. Ancient literature such as Rigveda, Yajurveda, Atharvaveda, CharakSamhita, and Sushrut Samhita also describes the use of plants for the treatment of various health problems. In recent times, the focus on plant research has increased worldwide, and a large body of evidence has been collected to show the immense potential of medicinal plants used in various traditional systems.Materials and Methods: The present study was carried out to evaluate the hepatoprotective activity of ethanolic extract of Cnidoscolus Phyllacanthus(ECP) leaves against D-galactosamine induced liver damage in Wistar rats. Hepatotoxicity was induced by D-Galactosamine (270 mg/kg body weight) administered intraperitoneally (i.p.) on the 14th day of a total two-week experiment. In contrast, the extract of the investigated plant was given orally throughout the whole experiment at 200 and 400 mg/kg body weight. Silymarin (100 mg/kg body weight) was given orally as a standard hepatoprotective drug.Results and Discussion: Histological studies showed that 400 mg/kg CP attenuated hepatocellular necrosis in d-GalN intoxicated rats. It was concluded from the results that the ethanolic extract of Cnidoscolus Phyllacanthus leaves reduces D-galactosamine-induced hepatotoxicity in rats.","PeriodicalId":13749,"journal":{"name":"INTERNATIONAL JOURNAL OF APPLIED PHARMACEUTICAL SCIENCES AND RESEARCH","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2022-03-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"79716177","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}