R. Mishra, R. Kaushik, Ajay Shukla, Smriti Ojha, Sudhanshu Mishra, R. S. Dubey
{"title":"IS ARTIFICIAL INTELLIGENCE VIZ M AND D LEARNING COULD BE THE SOLUTION PROMISING ALTERNATIVE TO ANIMALS: A LEARNING-BASED TOXICITY RECITATION?","authors":"R. Mishra, R. Kaushik, Ajay Shukla, Smriti Ojha, Sudhanshu Mishra, R. S. Dubey","doi":"10.31069/japsr.v5i2.01","DOIUrl":null,"url":null,"abstract":"Similar to animal and human studies, the data show that when many animal models are extrapolated to humans, reliability is limited when it comes to predicting drug effects. This leads to an unbalanced waste of time and money and nightmares during drug development because the drug works well in animals or pre-clinical models and therefore fails in clinical studies or clinical trials, or vice versa. In this technique, machine and deep learning (M and D) is a subset of artificial intelligence. We hope this will eliminate the need for lengthy searches, reduce the number of animals sacrificed in the strategy, and reduce the cost and time required for testing. We recognize that full replacement of animals in toxicological or pre-clinical studies and tests remains a challenge - we acknowledge M and D learning-based animal toxicity prediction can be the key.","PeriodicalId":13749,"journal":{"name":"INTERNATIONAL JOURNAL OF APPLIED PHARMACEUTICAL SCIENCES AND RESEARCH","volume":null,"pages":null},"PeriodicalIF":0.0000,"publicationDate":"2022-09-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"INTERNATIONAL JOURNAL OF APPLIED PHARMACEUTICAL SCIENCES AND RESEARCH","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.31069/japsr.v5i2.01","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
引用次数: 0
Abstract
Similar to animal and human studies, the data show that when many animal models are extrapolated to humans, reliability is limited when it comes to predicting drug effects. This leads to an unbalanced waste of time and money and nightmares during drug development because the drug works well in animals or pre-clinical models and therefore fails in clinical studies or clinical trials, or vice versa. In this technique, machine and deep learning (M and D) is a subset of artificial intelligence. We hope this will eliminate the need for lengthy searches, reduce the number of animals sacrificed in the strategy, and reduce the cost and time required for testing. We recognize that full replacement of animals in toxicological or pre-clinical studies and tests remains a challenge - we acknowledge M and D learning-based animal toxicity prediction can be the key.