International Journal of Adhesion and Adhesives最新文献

{"title":"Adhesive modifiers for bitumen obtained from coumarone-indene fractions of liquid coal coking products","authors":"Serhiy Pyshyev ,&nbsp;Yuriy Prysiazhnyi ,&nbsp;Yuriy Demchuk ,&nbsp;Guri Isaiah Borbeyiyong ,&nbsp;Nataliya Vytrykush","doi":"10.1016/j.ijadhadh.2024.103933","DOIUrl":"10.1016/j.ijadhadh.2024.103933","url":null,"abstract":"<div><div>Modifiers are added to road bitumens to enhance their properties. The only significant disadvantage of current industrial modifiers is their relatively high cost. The authors develop a new way to solve this problem by using relatively cheap raw materials for obtaining effective adhesive modifiers for bitumen, namely, coal coking liquid products. Therefore, coumarone-indene resin (CIR) and coumarone-indene-carbazole resin (CICR) were obtained by ionic co-oligomerization based on fractions extracted from liquid products of coal coking (gasoline fractions and coal tar). When added in an amount of 7 wt%, CIR increases temperature resistance and doubles the adhesive properties of bitumens. However, CIR degrades the plasticity of bitumens, so to produce polymer-modified bitumen (PMB) cheap plasticizers (petroleum tar and resin from the decomposition of the organic mass of brown coal) must be used. CICR has practically no effect on the temperature resistance of bitumens, slightly improves their plasticity, and doubles the adhesion to glass at a content of 1 % wt.%. The CIR and CICR use will make it possible to obtain relatively inexpensive PMB.</div></div>","PeriodicalId":13732,"journal":{"name":"International Journal of Adhesion and Adhesives","volume":"138 ","pages":"Article 103933"},"PeriodicalIF":3.2,"publicationDate":"2024-12-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143167994","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"材料科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Comparison of adhesive system bond strength in composite restoration repairs: A systematic review and meta-analysis of in vitro studies","authors":"Fiorella Elizabeth Arévalo Tarrillo,&nbsp;Laura Cristina Leite Nardello,&nbsp;Mary Caroline Skelton Macedo,&nbsp;Maria Ângela Pita Sobral","doi":"10.1016/j.ijadhadh.2024.103929","DOIUrl":"10.1016/j.ijadhadh.2024.103929","url":null,"abstract":"<div><div>Repairing localized failures in restorations can be as durable as complete replacement, offering a more conservative and efficient alternative. However, no \"standard\" protocol or ideal materials currently exist for this procedure. This systematic review (PROSPERO CRD42022322572) investigated different adhesive systems (Total-etch, Self-etch, and Universal) in repairing direct composite restorations. The review included <em>in vitro</em> studies that evaluated bond strength in composite repairs after surface roughening. A comprehensive literature searches up to April 18, 2022, across six databases (PubMed, Scopus, Web of Science, Embase, LILACS and BDTL), identified 133 relevant studies from an initial 1357, with 15 meeting the inclusion criteria. Fourteen of these studies underwent quantitative analysis and meta-analysis. Quality Assessment Tool for <em>In Vitro</em> Studies was used to evaluate methodological quality. The meta-analysis was performed with R Studio, used the standardized mean difference with a 95 % confidence interval to assess bond strength. The random-effects study heterogeneity using the I-squared statistic. Tensile/microtensile studies found that Total-etch systems were more effective in enhancing bond strength, whereas shear and micro-shear studies favored Self-etch systems. The Universal adhesives showed inconsistent results between the two bond strength tests. Both types of studies, demonstrated that employing an adhesive system enhances bond strength in repairs. The review highlights the need for standardized research to achieve more definitive conclusions.</div></div>","PeriodicalId":13732,"journal":{"name":"International Journal of Adhesion and Adhesives","volume":"138 ","pages":"Article 103929"},"PeriodicalIF":3.2,"publicationDate":"2024-12-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143169154","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"材料科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Synergistic effects of a bionic villi structure and multiple hydrogen bonds on the increase in interfacial bonding strength of a 30-wt.% GF/PET-2024 aluminum alloy","authors":"Baojia Cheng,&nbsp;Lina Lu,&nbsp;Leyao Xu,&nbsp;Haoyu Wang,&nbsp;Ben Ma,&nbsp;Anbo Du,&nbsp;Shumei Lou","doi":"10.1016/j.ijadhadh.2024.103932","DOIUrl":"10.1016/j.ijadhadh.2024.103932","url":null,"abstract":"<div><div>In recent years, metal‒thermoplastic polymer hybrid joints have been widely used in lightweight advanced aircraft and new energy vehicles. In this work, the method of machine milling + FeCl₃ corrosion + coating KH-892 was used to construct a viscous bionic villi structure on the surface of A2024 aluminum alloy, which greatly improved the interfacial bonding strength of a 30-wt.% glass fiber-reinforced PET-A2024 aluminum alloy joint (expressed as 30-wt.% GF/PET-A2024 joint). The synergistic action of the millimeter column produced by milling and the micron-scale porous structure produced by corrosion results in multiscale mechanical interlocking and increases the interfacial bonding strength of 30-wt.% GF/PET-A2024 to 44.2 MPa, which is 13.7 times greater than that of untreated joint. FTIR results show that the KH-892 coating can change the viscosity of the villi surface, which makes it easier for the bionic villi surface to bond with PET. Under the action of millimeter‒micron multiscale mechanical interlocking and multiple hydrogen bonds, the interfacial bonding strength of 30-wt.% GF/PET-A2024 increases to 54.8 MPa.</div></div>","PeriodicalId":13732,"journal":{"name":"International Journal of Adhesion and Adhesives","volume":"138 ","pages":"Article 103932"},"PeriodicalIF":3.2,"publicationDate":"2024-12-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143168000","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"材料科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Can bioactive glasses compensate for polymer degradation in adhesive systems and reduce dentin permeability over time?","authors":"Amanda Márcia Maia Souza ,&nbsp;Paulo Vitor Campos Ferreira ,&nbsp;Felipe Silva Gomes ,&nbsp;Luanna Marinho Sereno Nery ,&nbsp;Ceci Nunes Carvalho ,&nbsp;José Bauer ,&nbsp;Darlon Martins Lima","doi":"10.1016/j.ijadhadh.2024.103926","DOIUrl":"10.1016/j.ijadhadh.2024.103926","url":null,"abstract":"<div><h3>Objective</h3><div>To evaluate the dentin permeability of experimental adhesive systems incorporated with 45S5 and NbG bioactive glasses (10 % and 20 %), compared to an experimental adhesive without bioactive glass after 12 months of storage in PBS.</div></div><div><h3>Methods</h3><div>Two-step self-etching adhesiv systems containing 10 % and 20 % by weight of 45S5 and NbG bioactive glasses were tested on forty freshly extracted human teeth. An experimental adhesive without microparticles was used as a control group. Dentin permeability was evaluated immediately after adhesive system application, 30 days, and 12 months after storage in PBS. The formation of nanoprecipitates on the dentin surface and within the tubules was analyzed at the end of the permeability tests using SEM/EDS. For statistical analysis, data were subjected to Shapiro-Wilk tests, two-way repeated measures ANOVA (<em><u>Material x Time</u></em>) and Holm-Sidak (α = 5 %).</div></div><div><h3>Results</h3><div>There was a statistically significant interaction between Material and Time (p &lt; 0.001). Significant differences were observed in the reduction of dentin permeability values among the adhesive systems evaluated after 12 months of immersion in PBS (p &lt; 0.001). All adhesive systems containing bioactive glass showed the lowest dentin permeability values compared to the control adhesive (p &lt; 0.001). SEM images showed mineral precipitation on the surface of the samples and microparticles and precipitates at the entrance of the dentinal tubules in the bioactive adhesive groups.</div></div><div><h3>Conclusion</h3><div>The addition of 45S5 and NbG bioactive glass at concentrations of 10 % and 20 % to an experimental adhesive system decreased the dentin permeability of the specimens evaluated after 12 months of immersion in PBS compared to the same adhesive system without the addition of bioactive material.</div></div>","PeriodicalId":13732,"journal":{"name":"International Journal of Adhesion and Adhesives","volume":"138 ","pages":"Article 103926"},"PeriodicalIF":3.2,"publicationDate":"2024-12-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143168974","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"材料科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Effect of DTPMP pretreatment on intraradicular dentin push-out bond strength and etching pattern of self-adhesive and conventional dual cure resin cement","authors":"Diego Neves Pinto ,&nbsp;Tainah Oliveira Rifane ,&nbsp;Manuela Timbó Farrapo ,&nbsp;Ketelyn Kerty Moreira de Oliveira ,&nbsp;Samara Tabata Medeiros ,&nbsp;Vitaliano Gomes de Araújo-Neto ,&nbsp;Salvatore Sauro ,&nbsp;Diego Martins de Paula ,&nbsp;Victor Pinheiro Feitosa","doi":"10.1016/j.ijadhadh.2024.103931","DOIUrl":"10.1016/j.ijadhadh.2024.103931","url":null,"abstract":"<div><h3>Objective</h3><div>To evaluate the push-out bond strength (PBS) and conditioning effects of diethylenetriamine-penta-phosphonic acid (DTPMP), as a pretreatment of intra-radicular dentin compared to ethylenediamine tetra-acetic acid (EDTA) and orthoorthophosphoric acid 37 % (H3PO4) for cementing posts with dual cure resin cement.</div></div><div><h3>Material and methods</h3><div>The resin cements employed were dual-cure resin cement RelyX ARC with previous Single Bond Universal adhesive (ARC/SBU) application, and self-adhesive resin cement RelyX U200. A fifty-four bovine incisor roots were prepared for GFP cementation and randomly divided into six groups according to the type of cement and dentin pre-treatment: 1) U200: no previous treatment; 2) EDTA-U200: pretreatment with 15 % EDTA for 3 min; 3) DTPMP-U200: pretreatmentwith 15 % DTPMP for 3 min; 4) H3PO4-ARC: 37 % orthophosphoric acid for 15s + SBU; 5) EDTA-ARC: 15 % EDTA for 3 min + SBU; and 6) DTPMP-ARC: 15 % DTPMP for 3 min + SBU. The roots (n = 6 per group) were sectioned into disc specimens of 1 mm (thickness) and subjected to PBS at 24h and after aging by <em>Clostridium histolyticum</em>. Additionally, root treated with each pre-treatment, without the application of adhesive or cement, disc specimens were subjected to scanning electron microscopy (SEM) to analyze the dentin surface conditioning pattern (n = 3)<strong>.</strong> Data were analyzed by two-way ANOVA and Tukey's test (p &lt; 0.05).</div></div><div><h3>Results</h3><div>In PBS, DTPMP-U200 and DTPMP-ARC (p &lt; 0.001) presented the highest bond strength after aging. The DTPMP etching pattern showed intense etching with mineral maintenance, while EDTA and H3PO4 showed greater exposure of collagen fibrils.</div></div><div><h3>Conclusions</h3><div>Treatment using 15 % DTPMP as an intraradicular dentin conditioner before luting glass-fiber posts provides bonding stability and potential for therapeutic remineralization.</div></div>","PeriodicalId":13732,"journal":{"name":"International Journal of Adhesion and Adhesives","volume":"138 ","pages":"Article 103931"},"PeriodicalIF":3.2,"publicationDate":"2024-12-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143168975","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"材料科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Novel polymer – Carbon nanotube composite coating for steel protection","authors":"Mostafa A. Shohide","doi":"10.1016/j.ijadhadh.2024.103930","DOIUrl":"10.1016/j.ijadhadh.2024.103930","url":null,"abstract":"<div><div>The main perspective of this research is to prepare a high-performance, low-cost, efficient protective coating. This has been achieved by using asphalt cement together with polyester as a source of hydroxyl groups by mixing ratio 4:1, forming a mixed polyol (MP). The hydroxyl number of MP was determined, and then MP reacted with the calculated amount of methylene diphenyl diisocyanate (MDI) according to the chosen NCO/OH molar ratio (1.3/1). Before the coating was formulated by a solvent, CNTs were added in different ratios (0.25, 0.5, 0.75 and 1.0) % of the coating weight, forming a protective coating named as asphaltic polyurethane (AsPU-CNTs). The prepared coatings were applied to the steel surface and then evaluated. The obtained results of the study detected that the optimum CNTs percent for enhancing the physic-mechanical and protective performance of the coating is 0.75, as follows: Drying time decreased by 35 % as compared with the control sample (without CNTs); meanwhile, both Dry Film Thickness (DFT) and adhesion strength increased by 10 % and 54 %, respectively. Blending AsPU with 0.75 % CNTs enhanced the hydrophobicity by increasing the contact angle of the coating by 49 %. Abrasion and fire resistance were improved by 17 % and 56 %, respectively. Lastly, the resistance of the coatings was changed from fair to excellent for both chemicals and crude oil.</div></div>","PeriodicalId":13732,"journal":{"name":"International Journal of Adhesion and Adhesives","volume":"138 ","pages":"Article 103930"},"PeriodicalIF":3.2,"publicationDate":"2024-12-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143168976","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"材料科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"A xylem fiber cell walls-inspired high-performance and multifunctional soy protein isolate adhesive with a double cross-linked strengthening network","authors":"Hui Chen ,&nbsp;Ying Zhang ,&nbsp;Yi Tan ,&nbsp;Jiawei Shao ,&nbsp;Xinyi Li ,&nbsp;Mingyang Bai ,&nbsp;Shanshan Gong ,&nbsp;Tao Liu ,&nbsp;Jianzhang Li","doi":"10.1016/j.ijadhadh.2024.103928","DOIUrl":"10.1016/j.ijadhadh.2024.103928","url":null,"abstract":"<div><div>Soy protein isolate (SPI) adhesive, derived from a green and low-cost sustainable biomass resource, is as an excellent alternative for fossil-based adhesives. However, the weak water-resistant bonding strength and vulnerability to mildew have hindered its practical industrial applications. Herein, inspired by the relationship between the structures and mechanical properties in cell wall of wood xylem fibers, a double cross-linked strengthening network is designed to prepare SPI adhesive with high bonding performance and mildew resistance. Functionalized lignocellulose (TOLC) acting as a skeleton, covalent interaction with SPI enhances the structural stability of the adhesive, enabling it to withstand higher loads, and the water-resistant bonding performance reaches 1.45 ± 0.09 MPa. Sodium lignosulfonate (LS) as a binder can establish a sacrificial bonding network, which provides an effective energy dissipation mechanism for the adhesive and increases the toughness by 379.23 %; meanwhile, as a natural antibacterial agent, it can effectively improve the mildew-resistant performance of SPI adhesive (5 days without mildew). This novel strategy of producing tough, multifunctional and green biomass adhesives by constructing simple double cross-linked strengthening networks provides a practical way to achieve efficient utilization of waste resources and promote sustainable development.</div></div>","PeriodicalId":13732,"journal":{"name":"International Journal of Adhesion and Adhesives","volume":"138 ","pages":"Article 103928"},"PeriodicalIF":3.2,"publicationDate":"2024-12-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143168972","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"材料科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Shear bond strenght of different repairing materials on 3D printed occlusal splints","authors":"Lucas Simino De Melo ,&nbsp;Priscila de Carvalho Nóbrega ,&nbsp;Rhayssa Pereira Ribeiro Do Amaral ,&nbsp;Lucas Fernando Tabata ,&nbsp;Rodrigo Antonio de Medeiros","doi":"10.1016/j.ijadhadh.2024.103927","DOIUrl":"10.1016/j.ijadhadh.2024.103927","url":null,"abstract":"<div><div>With the rise of new 3D printing technologies, occlusal splints are now widely produced using CAD/CAM (Computer-Aided Design/Computer-Aided Manufacture). Although new and more resistant materials are being developed, daily use can still lead to small chips or cracks in CAD/CAM occlusal splints. Repairing the splint requires the use of different materials, but knowledge on their adhesion properties is limited. The purpose of this study was to evaluate the microshear bond strength of 4 repair materials for 3D-printed occlusal devices: flowable resin, autopolymerizing acrylic resin, bis-acrylic resin, and 3D printer resin. A total of 30 disks were fabricated using 3D-printed occlusal device resin. After polishing and smoothing the surfaces, four different repair materials were applied within cylindrical tubes on each disk sample, without any surface pretreatment. Fifteen specimens were stored in distilled water at 37 °C for 24 h, while the other 15 specimens underwent thermocycling for 10 000 cycles. Shear bond testing was subsequently performed until specimen failure occurred. Data were analyzed using 2-way ANOVA (for each material and thermocycling effect) and the Tukey multiple comparison test (α = .05). Among the tested resins for 3D-printed occlusal devices, autopolymerizing acrylic resin demonstrated the most significant increase in shear bond strength and a balanced fracture pattern after aging, making it suitable for repairs. In contrast, bis-acrylic resin's initial high strength diminished after thermocycling (P &lt; .05).</div></div>","PeriodicalId":13732,"journal":{"name":"International Journal of Adhesion and Adhesives","volume":"138 ","pages":"Article 103927"},"PeriodicalIF":3.2,"publicationDate":"2024-12-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143168971","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"材料科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"In vitro mechanical properties assessment of newly developed orthodontic self-adhesive resins","authors":"Dana R. Mohammed ,&nbsp;Ali I. Ibrahim ,&nbsp;Sanjukta Deb","doi":"10.1016/j.ijadhadh.2024.103923","DOIUrl":"10.1016/j.ijadhadh.2024.103923","url":null,"abstract":"<div><h3>Objectives</h3><div>This study aimed to develop novel self-adhesive resins for orthodontic bracket bonding that can provide clinically acceptable bond strengths, leave minimal remnant adhesive and enamel damage upon bracket debonding.</div></div><div><h3>Materials and methods</h3><div>A plain self-adhesive resin was used as a control, from which three main modified self-adhesive resin groups were developed for bracket bonding: bioactive glass, strontium fluoride and grape seed extract. All groups were subjected to three artificial aging models prior to shear bond strength, adhesive remnant index, enamel damage index and micro-hardness assessments.</div></div><div><h3>Results</h3><div>All groups yielded clinically acceptable shear bond strength values. The addition of 0.5 % grape seed extract to plain self-adhesive resin+1 % bioactive glass yielded the highest shear bond strength, minimal adhesive remnant index and minimal enamel damage post debonding, yet the differences were statistically insignificant (p &gt; 0.05). The best performance regarding microhardness was displayed by the addition of 0.5 % grape seed extract.</div></div><div><h3>Conclusions</h3><div>The formulation (1 % bioactive glass+ 0.5 % grape seed extract) yielded clinically satisfactory shear bond strength, minimal adhesive residue, minimal enamel damage, and highest micro-hardness mean value as compared to the control and other experimental self-adhesive resin groups.</div></div>","PeriodicalId":13732,"journal":{"name":"International Journal of Adhesion and Adhesives","volume":"138 ","pages":"Article 103923"},"PeriodicalIF":3.2,"publicationDate":"2024-12-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143168970","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"材料科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"The influence of 2,4,6-trimethylbenzoyldiphenylphosphine oxide on the toxicity of dental resins: A systematic review of in vitro studies","authors":"Victor de Melo Soares,&nbsp;Andréa Cândido dos Reis,&nbsp;Mariana Lima da Costa Valente","doi":"10.1016/j.ijadhadh.2024.103922","DOIUrl":"10.1016/j.ijadhadh.2024.103922","url":null,"abstract":"<div><h3>Research question</h3><div>The 2,4,6-trimethylbenzoyldiphenylphosphine oxide (TPO) has emerged as a prominent photoinitiator in resin-based compositions but its biological safety is questioned. The research question was: Does the presence of TPO in resin-based dental materials influence its cytotoxicity and genotoxicity?</div></div><div><h3>Material and methods</h3><div>This research followed the Preferred Reporting Items for Systematic Reviews and Meta-Analyses guideline and was registered on the Open Science Framework (osf.io/sthvf). The literature was searched in the Science Direct, PubMed, Embase, Web of Science, Scopus, ProQuest and Google Scholar databases for articles published until July 2024. The inclusion criteria were studies evaluating the cytotoxicity and genotoxicity of TPO. The exclusion criteria were studies that did not evaluate TPO or that did not evaluate its cytotoxicity and genotoxicity in vitro or in vivo.</div></div><div><h3>Results</h3><div>463 studies were identified, and after removing duplicates and applying the eligibility criteria, 5 were included and assessed qualitatively. Except for one study which presented a moderate risk of bias, the other five presented a low risk of bias. The heterogeneity of the studies' methodology and the results allowed qualitative analysis and discussion.</div></div><div><h3>Conclusions</h3><div>The main limitation of TPO is its high toxicity, with higher cytotoxic levels than other photoinitiators. Replacing other photosensitive systems for TPO may not offer adequate cost-benefit for biomedical applications.</div></div>","PeriodicalId":13732,"journal":{"name":"International Journal of Adhesion and Adhesives","volume":"138 ","pages":"Article 103922"},"PeriodicalIF":3.2,"publicationDate":"2024-12-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143169160","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"材料科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}