International Forum of Allergy & Rhinology最新文献

{"title":"Role of social determinants of health on quality of life in pediatric chronic rhinosinusitis","authors":"Ryan S. Ziltzer MD, MPH,&nbsp;Sameer Shetty BS,&nbsp;Dominic Coutinho BS,&nbsp;Rafka Chaiban MD, MHCM,&nbsp;Chadi A. Makary MD","doi":"10.1002/alr.23420","DOIUrl":"10.1002/alr.23420","url":null,"abstract":"<div>\u0000 \u0000 <section>\u0000 \u0000 <h3> Key points</h3>\u0000 \u0000 <div>\u0000 <ul>\u0000 \u0000 <li>Social determinants of health link to worse quality of life in pediatric chronic rhinosinusitis.</li>\u0000 \u0000 <li>The area deprivation index (ADI) may serve to predict health disparities in these patients.</li>\u0000 </ul>\u0000 </div>\u0000 </section>\u0000 </div>","PeriodicalId":13716,"journal":{"name":"International Forum of Allergy & Rhinology","volume":"14 11","pages":"1827-1829"},"PeriodicalIF":7.2,"publicationDate":"2024-07-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141855388","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Transsphenoidal retrieval of a needlefish beak remnants from the optic canal.","authors":"Firas Sbeih, Henry W Zhou, Noel F Ayoub, Barak Ringel, Carolina A Chiou, Joseph F Rizzo, Benjamin S Bleier","doi":"10.1002/alr.23419","DOIUrl":"https://doi.org/10.1002/alr.23419","url":null,"abstract":"<p><strong>Key points: </strong>Penetrating orbital trauma from marine creatures, especially needlefish, should be considered after injuries sustained in open water. Advances in endoscopic sinus surgery have enabled surgeons to remove certain orbital foreign bodies through endoscopic endonasal approaches. 3D segmentation is a valuable pre-operative tool in complex endoscopic orbital cases.</p>","PeriodicalId":13716,"journal":{"name":"International Forum of Allergy & Rhinology","volume":" ","pages":""},"PeriodicalIF":7.2,"publicationDate":"2024-07-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141758554","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Response to the editor regarding “An eosinophil peroxidase activity assay predicts acute exacerbations in post-operative chronic rhinosinusitis”","authors":"Abigail Pulsipher PhD,&nbsp;Kristine A. Smith MD,&nbsp;Richard R. Orlandi MD,&nbsp;Conner J. Massey MD,&nbsp;Jeremiah A. Alt MD, PhD,&nbsp;Gretchen M. Oakley MD,&nbsp;Shaelene Ashby PhD","doi":"10.1002/alr.23409","DOIUrl":"10.1002/alr.23409","url":null,"abstract":"","PeriodicalId":13716,"journal":{"name":"International Forum of Allergy & Rhinology","volume":"14 9","pages":"1539-1540"},"PeriodicalIF":7.2,"publicationDate":"2024-07-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141758553","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Histopathologic evaluation of Asian-American patients with chronic rhinosinusitis with nasal polyps","authors":"Arthur W. Wu MD,&nbsp;Kevin Hur MD,&nbsp;Aria Jafari MD,&nbsp;Omar G. Ahmed MD,&nbsp;Philip G. Chen MD,&nbsp;Masayoshi Takashima MD,&nbsp;Elena E. Chang MD,&nbsp;Bonnie Balzer MD,&nbsp;Anna Matthew MD,&nbsp;Haodong Xu MD, PhD,&nbsp;Mukul Divatia MD,&nbsp;Benjamin Tam BA,&nbsp;Juliana Robledo DDS,&nbsp;Luv Amin BS,&nbsp;David J. Cvancara BS,&nbsp;Amisheila Kinua BS,&nbsp;Tariq A. Syed BS,&nbsp;Dominique L. Paderin BS,&nbsp;Dennis M. Tang MD","doi":"10.1002/alr.23417","DOIUrl":"10.1002/alr.23417","url":null,"abstract":"<div>\u0000 \u0000 <section>\u0000 \u0000 <h3> Key points</h3>\u0000 \u0000 <div>\u0000 <ul>\u0000 \u0000 <li>Asian-American (AA) patients with chronic rhinosinusitis with nasal polyps (CRSwNP) have comparable rates of tissue eosinophilia compared to Caucasians when defined as &gt;10 eosinophils/high-powered field (HPF).</li>\u0000 \u0000 <li>AA patients with CRSwNP have significantly higher incidence of mixed inflammation defined as &gt;10 eosinophils/HPF and &gt;10 neutrophils/HPF.</li>\u0000 </ul>\u0000 </div>\u0000 </section>\u0000 </div>","PeriodicalId":13716,"journal":{"name":"International Forum of Allergy & Rhinology","volume":"14 11","pages":"1822-1826"},"PeriodicalIF":7.2,"publicationDate":"2024-07-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141751633","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Diagnostic criteria for eosinophilic chronic rhinosinusitis: Comparative analysis and novel scoring system","authors":"Jae Yoon Lee MD,&nbsp;Do Hyun Kim MD, PhD,&nbsp;Sung Won Kim MD, PhD,&nbsp;Yeon Hee Im MD,&nbsp;Chan Soon Park MD, PhD,&nbsp;Dong Hyun Kim MD, PhD,&nbsp;Zainab Alkhars MD,&nbsp;Soo Whan Kim MD, PhD","doi":"10.1002/alr.23416","DOIUrl":"10.1002/alr.23416","url":null,"abstract":"<div>\u0000 \u0000 \u0000 <section>\u0000 \u0000 <h3> Background</h3>\u0000 \u0000 <p>Accurate identification of eosinophilic chronic rhinosinusitis is essentialg because its treatment and prognosis substantially differ from other subtypes.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Methods</h3>\u0000 \u0000 <p>This retrospective observational study included 640 patients who underwent endoscopic sinus surgery for chronic rhinosinusitis in a single tertiary center from January 2021 to December 2022. Receiver operating characteristic curves were generated to compare accuracy, sensitivity, specificity of the novel scoring system, and previous diagnostic criteria (Japanese Epidemiological Survey of Refractory Eosinophilic Chronic Rhinosinusitis, European Forum for Research and Education in Allergy and Airway Diseases, European Position Paper on Rhinosinusitis and Nasal Polyps, and Sakuma et al.) for predicting eosinophilic chronic rhinosinusitis (ECRS) by tissue eosinophil count ≥70 per high power field.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Results</h3>\u0000 \u0000 <p>Patients were randomly divided into estimation (<i>n</i> = 430) and validation (<i>n</i> = 210) groups. The area under the receiver operating characteristic curve for the novel score was 0.753 (95% confidence interval [CI], 0.670–0.835) in the estimation group, 0.729 (0.629–0.830) in the validation group, and 0.661 (0.584–0.738) in the 20-fold cross-validation with the entire dataset.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Conclusions</h3>\u0000 \u0000 <p>We propose a novel scoring system that incorporates three key parameters: “novel score = blood eosinophil (%) + total Lund–Mackay score of anterior ethmoid sinuses + 2 if nasal polyp present” greater than 7 can be reliably used for diagnosing ECRS. This system can facilitate decision-making processes regarding the administration of oral steroids and biologics targeting type 2 inflammation prior to surgical intervention.</p>\u0000 </section>\u0000 </div>","PeriodicalId":13716,"journal":{"name":"International Forum of Allergy & Rhinology","volume":"14 11","pages":"1746-1756"},"PeriodicalIF":7.2,"publicationDate":"2024-07-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141748135","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Longer-term surveillance imaging and endoscopy critical for majority of patients in detection of sinonasal malignancy recurrence","authors":"Catherine Kwiecien BS,&nbsp;Alan D. Workman MD, MTR,&nbsp;Jadyn Wilensky BS,&nbsp;David K. Lerner MD,&nbsp;Vinay K. Rathi MD, MBA,&nbsp;Jennifer E. Douglas MD,&nbsp;Michael A. Kohanski MD, PhD,&nbsp;Edward C. Kuan MD, MBA,&nbsp;James N. Palmer MD,&nbsp;Nithin D. Adappa MD","doi":"10.1002/alr.23412","DOIUrl":"10.1002/alr.23412","url":null,"abstract":"<div>\u0000 \u0000 \u0000 <section>\u0000 \u0000 <h3> Background</h3>\u0000 \u0000 <p>Sinonasal malignancy surveillance paradigms are often based on Head and Neck National Comprehensive Cancer Network guidelines, which do not recommend standard surveillance imaging beyond 6 months without concerning symptomatology or physical examination findings.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Methods</h3>\u0000 \u0000 <p>This was a retrospective analysis of all patients who underwent resection of sinonasal malignancy at a tertiary care center over a 20-year period from 2000 to 2020, with an ensuing surveillance period demonstrating recurrence.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Results</h3>\u0000 \u0000 <p>Fifty-two patients with sinonasal malignancy recurrence were included, with an average time to recurrence of 30.9 months and a follow-up period of over 60 months. Recurrence was diagnosed by routine imaging or endoscopy in asymptomatic patients in a majority (60%) of cases, while the remaining minority of diagnoses followed new symptomatology. Asymptomatic recurrence was associated with perineural spread of tumor at initial resection (<i>p</i> = 0.025), but not with age (<i>p</i> = 0.85) or stage at diagnosis (<i>p</i> = 0.68). Expectedly, positron emission tomography/computed tomography (CT) more often detected regional or distant recurrence, while structural imaging (CT/magnetic resonance imaging) demonstrated more frequent detection of recurrence in those with perineural spread of tumor (<i>p</i> = 0.01).</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Conclusions</h3>\u0000 \u0000 <p>Our findings support high rates of asymptomatic recurrence in sinonasal malignancy, with the majority of recurrences diagnosed by routine endoscopy or imaging. Tailored and extended surveillance guidelines are necessary relative to those utilized for other head and neck mucosal cancers, and are especially appropriate when features such as perineural spread are present.</p>\u0000 </section>\u0000 </div>","PeriodicalId":13716,"journal":{"name":"International Forum of Allergy & Rhinology","volume":"14 11","pages":"1739-1745"},"PeriodicalIF":7.2,"publicationDate":"2024-07-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://onlinelibrary.wiley.com/doi/epdf/10.1002/alr.23412","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141748136","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Efficacy of acupuncture for allergic rhinitis in children: Systematic review and meta‑analysis with trial sequential analysis","authors":"Qinwen Xiao PhD,&nbsp;Zhichao Ni MD,&nbsp;Rongyu Wang PhD,&nbsp;Wen Jiang MD,&nbsp;Jinyao Yuan MD","doi":"10.1002/alr.23414","DOIUrl":"10.1002/alr.23414","url":null,"abstract":"<div>\u0000 \u0000 \u0000 <section>\u0000 \u0000 <h3> Background</h3>\u0000 \u0000 <p>Acupuncture has been shown for the treatment of allergic rhinitis in previous studies. Nevertheless, relevant evidence was lacked for paediatric patients with allergic rhinitis. We aim to validate the efficacy of acupuncture for allergic rhinitis in children by meta-analysis and trial sequence analysis.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Method</h3>\u0000 \u0000 <p>Comprehensive search of eight databases were conducted until August 27, 2023. Randomized controlled trials comparing acupuncture alone or in combination with drugs versus medication in children with AR were included. The primary outcome was total nasal symptom score (TNSS). The secondary outcomes were serum immunoglobulin E levels, and relapse rates.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Results</h3>\u0000 \u0000 <p>Thirteen studies involving 1186 participants were included. In results, acupuncture group (AC group) versus medication group (Med group) shows no significant difference in the treatment of AR in children (risk ratio [RR] = 1.10, 95% CI = 0.97 to 1.24, <i>p</i> = 0.13), while TSA suggested the included sample size did not exceed required information size (RIS). Significant differences were found between the AC + Med group versus the Med group (RR = 1.29, 95% CI = 1.17 to 1.42, p &lt; 0.00001), with sufficient sample size. Results in serum IgE after treatment which favored the Med group (MD = 51.94, 95% CI [22.24, 81.65], <i>p</i> = 0.0006). In terms of relapse rate, The AC group had a lower relapse rate than the Med group (RR = 0.40, 95% CI = 0.26–0.63, p &lt; 0.0001).</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Conclusions</h3>\u0000 \u0000 <p>Acupuncture is an efficacious treatment for allergic rhinitis in children, but this conclusion might be limited by the generally low quality of evidence. TSA suggested additional high-quality trials with larger sample sizes and longer treatment durations were needed.</p>\u0000 </section>\u0000 </div>","PeriodicalId":13716,"journal":{"name":"International Forum of Allergy & Rhinology","volume":"14 9","pages":"1488-1500"},"PeriodicalIF":7.2,"publicationDate":"2024-07-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141626726","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Gender-based linguistic differences in letters of recommendation for rhinology fellowship over time: A dual-institutional follow-up study using natural language processing and deep learning","authors":"Vikram Vasan BA,&nbsp;Christopher P. Cheng AB,&nbsp;Shaun Edalati BS,&nbsp;Shreya Mandloi BS,&nbsp;David K. Lerner MD,&nbsp;Anthony Del Signore MD,&nbsp;Madeleine Schaberg MD,&nbsp;Satish Govindaraj MD,&nbsp;Mindy Rabinowitz MD,&nbsp;Gurston Nyquist MD,&nbsp;Alfred Marc Iloreta MD","doi":"10.1002/alr.23411","DOIUrl":"10.1002/alr.23411","url":null,"abstract":"<div>\u0000 \u0000 <section>\u0000 \u0000 <h3> Key points</h3>\u0000 \u0000 <div>\u0000 <ul>\u0000 \u0000 <li>This follow-up dual-institutional and longitudinal study further evaluated for underlying gender biases in LORs for rhinology fellowship.</li>\u0000 \u0000 <li>Explicit and implicit linguistic gender bias was found, heavily favoring male applicants</li>\u0000 </ul>\u0000 </div>\u0000 </section>\u0000 </div>","PeriodicalId":13716,"journal":{"name":"International Forum of Allergy & Rhinology","volume":"14 11","pages":"1814-1817"},"PeriodicalIF":7.2,"publicationDate":"2024-07-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141619886","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"There is no sinus without “us”: A randomized controlled study assessing the efficacy of shared decision-making in the surgical management of chronic rhinosinusitis","authors":"Vivienne Li BA,&nbsp;Andrew Yousef MD,&nbsp;Divya Prajapati MD,&nbsp;Michael Oca BS,&nbsp;Leslie Gomez FNP,&nbsp;Adam S. DeConde MD,&nbsp;Carol H. Yan MD","doi":"10.1002/alr.23407","DOIUrl":"10.1002/alr.23407","url":null,"abstract":"<div>\u0000 \u0000 <section>\u0000 \u0000 <h3> Key points</h3>\u0000 \u0000 <div>\u0000 <ul>\u0000 \u0000 <li>CRS patients exhibit little decision conflict in their choice of pursuing surgery.</li>\u0000 \u0000 <li>Standard counseling alone appears to suffice once patients express an interest in surgery.</li>\u0000 \u0000 <li>Decision aids may increase patient knowledge and improve postoperative care understanding.</li>\u0000 </ul>\u0000 </div>\u0000 </section>\u0000 </div>","PeriodicalId":13716,"journal":{"name":"International Forum of Allergy & Rhinology","volume":"14 11","pages":"1810-1813"},"PeriodicalIF":7.2,"publicationDate":"2024-07-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141619887","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"A methodological pipeline for the preclinical evaluation of novel topical agents for the treatment of CRS","authors":"Samuel J. M. Hale MB, ChB, BMedSc(Hons),&nbsp;Christian A. Lux PhD,&nbsp;James E. Willoughby,&nbsp;Arne Koefoed BSc,&nbsp;David Broderick PhD,&nbsp;Kristi Biswas PhD,&nbsp;Raymond Kim MB, ChB, PhD,&nbsp;Brett Wagner Mackenzie PhD,&nbsp;Richard G. Douglas MD","doi":"10.1002/alr.23418","DOIUrl":"10.1002/alr.23418","url":null,"abstract":"<div>\u0000 \u0000 <section>\u0000 \u0000 <h3> Key points</h3>\u0000 \u0000 <div>\u0000 <ul>\u0000 \u0000 <li>Novel topical therapeutics require extensive pre-clinical testing to assess efficacy and safety.</li>\u0000 \u0000 <li>Antibiofilm or immunosuppressant agents can utilize ex vivo models to measure ciliotoxicity.</li>\u0000 \u0000 <li>Agents that are found to be effective and non-toxic ex vivo warrant further investigation in vivo.</li>\u0000 </ul>\u0000 </div>\u0000 </section>\u0000 </div>","PeriodicalId":13716,"journal":{"name":"International Forum of Allergy & Rhinology","volume":"14 11","pages":"1818-1821"},"PeriodicalIF":7.2,"publicationDate":"2024-07-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://onlinelibrary.wiley.com/doi/epdf/10.1002/alr.23418","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141619885","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}