International Forum of Allergy & Rhinology最新文献_第7页

Ambient particulate matter and frequency of outpatient visits for chronic rhinosinusitis in the United States. 美国环境颗粒物与慢性鼻炎门诊就诊频率。

IF 7.2 2区医学

International Forum of Allergy & Rhinology Pub Date : 2024-10-30 DOI: 10.1002/alr.23477

Hong-Ho Yang, David Grimm, Esther Velasquez, Peter H Hwang

{"title":"Ambient particulate matter and frequency of outpatient visits for chronic rhinosinusitis in the United States.","authors":"Hong-Ho Yang, David Grimm, Esther Velasquez, Peter H Hwang","doi":"10.1002/alr.23477","DOIUrl":"https://doi.org/10.1002/alr.23477","url":null,"abstract":"Background: Emerging evidence has underscored the harmful effects of air pollution on the upper airway. We investigated the relationship between ambient particulate matter (PM) level and the frequency of outpatient visits for chronic rhinosinusitis (CRS).Methods: We conducted an ecological cohort study of US adults enrolled in The Merative MarketScan outpatient database from 2007 to 2020. For each geographical subunit (core-based statistical area [CBSA]), we calculated the annual rate of CRS-related outpatient visits per 1000 well-patient checkup visits (CRS-OV). Using data from the Environmental Protection Agency's Air Quality System, we mapped the rolling statistical average of daily PM2.5 and PM10 over the preceding year onto each CBSA × year combination. We employed multivariable negative binomial regression modeling to estimate the association between PM levels and subsequent CRS-OV.Results: Across 3933 observations (CBSA × year combinations), encompassing ∼4 billion visits, the median CRS-OV was 164 (interquartile range 110-267). The mean PM2.5 level was 8.9 µg/m3 (SD 2.6) and the mean PM10 level was 20.2 µg/m3 (SD 7.2). Adjusting for patient demographics and respiratory comorbidities, a compounded rise in subsequent CRS-OV was observed with increasing PM levels. Each µg/m3 rise in PM2.5 independently predicted a 10% increase in CRS-OV (adjusted incidence rate ratio [aIRR]) 1.10, 95% confidence interval [CI] 1.08-1.13) and each µg/m3 rise in PM10 independently predicted a 3% increase in CRS-OV (aIRR 1.03, 95% CI 1.02-1.04).Conclusion: Elevated ambient PM2.5 and PM10 levels are associated with a subsequent compounded increase in the frequency of CRS-OV, with PM2.5 predicting a more pronounced rise compared to PM10.","PeriodicalId":13716,"journal":{"name":"International Forum of Allergy & Rhinology","volume":" ","pages":""},"PeriodicalIF":7.2,"publicationDate":"2024-10-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142545275","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Viral infection as an inciting event for development of chronic rhinosinusitis: A population-based study. 病毒感染是慢性鼻炎发病的诱因：一项基于人群的研究。

IF 7.2 2区医学

International Forum of Allergy & Rhinology Pub Date : 2024-10-30 DOI: 10.1002/alr.23482

Najm S Khan, Heli Majeethia, Vincent Provasek, Faizaan Khan, Zain Mehdi, Aatin K Dhanda, Jeffrey T Vrabec, Edward D McCoul, Chadi A Makary, Masayoshi Takashima, Omar G Ahmed

引用次数: 0

Letter to the editor regarding “Role of social determinants of health on quality of life in pediatric chronic rhinosinusitis”: Enhancing patient-centered care in underdeveloped regions 就 "健康的社会决定因素对小儿慢性鼻炎患者生活质量的影响 "致编辑的信：在欠发达地区加强以患者为中心的护理。

IF 7.2 2区医学

International Forum of Allergy & Rhinology Pub Date : 2024-10-27 DOI: 10.1002/alr.23479

Huimin Du MMed, Tong Wu MMed

引用次数: 0

Development and validation of the four-item Concise Aging adults Smell Test to screen for olfactory dysfunction in older adults. 开发并验证用于筛查老年人嗅觉功能障碍的四项简明老年人嗅觉测试。

IF 7.2 2区医学

International Forum of Allergy & Rhinology Pub Date : 2024-10-27 DOI: 10.1002/alr.23476

Zachary M Soler, Mathew J Gregoski, Preeti Kohli, Kristina A LaPointe, Rodney J Schlosser

{"title":"Development and validation of the four-item Concise Aging adults Smell Test to screen for olfactory dysfunction in older adults.","authors":"Zachary M Soler, Mathew J Gregoski, Preeti Kohli, Kristina A LaPointe, Rodney J Schlosser","doi":"10.1002/alr.23476","DOIUrl":"https://doi.org/10.1002/alr.23476","url":null,"abstract":"Background: Olfactory dysfunction (OD) in the elderly is common and associated with numerous comorbidities, yet often underrecognized. This study sought to develop an instrument for widespread screening of this condition.Methods: Demographic factors, comorbidities, and olfactory-related questions were examined in a focus group (N = 20) and development cohort (N = 190). The 4-item Concise Aging adults Smell Test (4-CAST) screening instrument was then developed to predict OD on Sniffin Sticks testing. An independent validation cohort (N = 147) was then examined to confirm ability of the 4-CAST to predict OD on Smell Identification Test 40 (SIT40).Results: The most important variables for predicting olfactory loss in older subjects were age, type II diabetes status, Visual Analog Scale (VAS) of overall rating of smell, and VAS of impact of smell upon safety. In the development cohort, the 4-CAST model yielded predictive probability (area under the curve) of 0.805 (p < 0.001) for predicting the bottom 25th percentile on Sniffin Sticks. Results were similar in the validation cohort, as the 4-CAST accurately classified 83.8% subjects (area under the curve [AUC] 0.789, p < 0.001) in the bottom 25th percentile of SIT40 testing. The 4-CAST was able to accurately classify 89.4% of subjects with anosmia.Conclusion: The 4-CAST is a quick screening instrument for predicting OD in older adults and has similar performance characteristics in independent populations using the two most common validated olfactory tests. Given the high prevalence of unrecognized olfactory loss in this population, this can be a useful tool for practitioners to determine which subjects may benefit from more extensive olfactory testing.","PeriodicalId":13716,"journal":{"name":"International Forum of Allergy & Rhinology","volume":" ","pages":""},"PeriodicalIF":7.2,"publicationDate":"2024-10-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142499713","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

A cradle-to-grave life cycle assessment of the endoscopic sinus surgery considering materials, energy, and waste. 对内窥镜鼻窦手术进行从摇篮到坟墓的生命周期评估，考虑材料、能源和废物。

IF 7.2 2区医学

International Forum of Allergy & Rhinology Pub Date : 2024-10-27 DOI: 10.1002/alr.23474

Zeinab Mousania, Darpan Kayastha, Ryan A Rimmer, John D Atkinson

{"title":"A cradle-to-grave life cycle assessment of the endoscopic sinus surgery considering materials, energy, and waste.","authors":"Zeinab Mousania, Darpan Kayastha, Ryan A Rimmer, John D Atkinson","doi":"10.1002/alr.23474","DOIUrl":"https://doi.org/10.1002/alr.23474","url":null,"abstract":"Background: Operating rooms generate 1.8 million tons of waste annually, or 20%‒30% of the total healthcare waste in the United States. Our objective was to perform a life cycle assessment (LCA) for endoscopic sinus surgeries (ESSs) in order to analyze its environmental impact.Methods: A comprehensive LCA of ESS was performed considering energy, climate, and water use impacts associated with the materials and processes used. It focuses on the ESS performed at a large tertiary academic hospital and then extends the impacts to consider annual US surgeries. The assessment considers end-of-life waste management at both landfills and incinerators.Results: Single-use instrument production constitutes 89%‒96% of the total impacts throughout the life cycle of an ESS. Waste-to-energy incineration is shown to be a preferred end-of-life destination, as it recovers much of the input production energy of plastic items, ultimately reducing the input to 36%, although this is done at the expense of higher greenhouse gas emissions. For multi-use items, decontamination dominates environmental impact (>99% of totals), but consideration of reusable items reduces overall energy consumption and global warming potential (GWP) by 25%‒33%.Conclusion: Single-use items dominate the total environmental impact of ESS. While multi-use items require additional decontamination over their lifetimes, results show that their incorporation reduces energy consumption and GWP by 25%‒33%, demonstrating the clear environmental benefit.","PeriodicalId":13716,"journal":{"name":"International Forum of Allergy & Rhinology","volume":" ","pages":""},"PeriodicalIF":7.2,"publicationDate":"2024-10-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142499711","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Reply to the letter to the editor regarding “Role of Social Determinants of Health on Quality of Life in Pediatric Chronic Rhinosinusitis”: Enhancing patient-centered care in underdeveloped regions 回复有关 "健康的社会决定因素对小儿慢性鼻炎患者生活质量的影响 "的致编辑信：在欠发达地区加强以患者为中心的护理。

IF 7.2 2区医学

International Forum of Allergy & Rhinology Pub Date : 2024-10-27 DOI: 10.1002/alr.23478

Ryan S. Ziltzer MD, MPH, Sameer Shetty BS, Dominic Coutinho BS, Rafka Chaiban MD, MHCM, Chadi A. Makary MD

引用次数: 0

Perioperative adjuvant therapy with short course of dupilumab with ESS for recurrent CRSwNP. 针对复发性 CRSwNP，使用短疗程的双鲁单抗和 ESS 进行围手术期辅助治疗。

IF 7.2 2区医学

International Forum of Allergy & Rhinology Pub Date : 2024-10-23 DOI: 10.1002/alr.23471

Audrey Pelletier, Leandra Mfuna Endam, Emmanuel Gonzalez, Sheherazade Jannat, Thea Irani, Martin Desrosiers

{"title":"Perioperative adjuvant therapy with short course of dupilumab with ESS for recurrent CRSwNP.","authors":"Audrey Pelletier, Leandra Mfuna Endam, Emmanuel Gonzalez, Sheherazade Jannat, Thea Irani, Martin Desrosiers","doi":"10.1002/alr.23471","DOIUrl":"https://doi.org/10.1002/alr.23471","url":null,"abstract":"Background: Chronic rhinosinusitis with nasal polyposis (CRSwNP) is associated with a high rate of disease recurrence following endoscopic sinus surgery (ESS). Type 2 disease is associated with a higher incidence of recurrence and is believed to impact disease resolution via interference with epithelial healing and pathogen immunity. We wished to verify if perioperative control of Type 2 inflammation with an anti-IL4/IL13 targeting monoclonal antibody and during the resolution period following surgery leads to better control of the disease long term.Methods: In this prospective, placebo-controlled, double-blinded trial. Thirty adult subjects with recurrent CRSwNP underwent ESS plus or minus 14 weeks of perioperative dupilumab, initiated 4 weeks (two injections) pre-ESS. Subjective and objective parameters of nasal patency, olfaction, quality of life (QoL), and adverse events were monitored up to 52 weeks post-ESS. Microbiological culture was performed to characterize pathogens colonization under both conditions.Results: ESS safely improved subjective and objective measures of nasal patency, olfaction, and QoL in both groups. Olfaction was conserved longer in the dupilumab-treated group, with 33.3% of subjects presenting anosmia at 12 months after ESS in the dupilumab group compared to 50.0% with placebo. This was associated with persistent decreases in serum IgE, which were not seen with placebo treatment. No unusual safety signals were observed.Conclusion: Short-course adjuvant perioperative treatment with dupilumab is associated with improved long-term olfactory outcomes and persistent lowering of serum IgE.","PeriodicalId":13716,"journal":{"name":"International Forum of Allergy & Rhinology","volume":" ","pages":""},"PeriodicalIF":7.2,"publicationDate":"2024-10-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142499715","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Potential of observing the diameter of the optic nerve sheath using computed tomography in diagnosing high intracranial pressure in patients with spontaneous CSF rhinorrhea. 使用计算机断层扫描观察视神经鞘直径在诊断自发性 CSF 鼻出血患者颅内压增高方面的潜力。

IF 7.2 2区医学

International Forum of Allergy & Rhinology Pub Date : 2024-10-23 DOI: 10.1002/alr.23475

Shunke Li, Zengxiao Zhang, Huijuan Zhao, Xuehui Li, Lin Wang, Jisheng Zhang, Lin Han, Xudong Yan, Liwei Jiang, Zhaoxia Wei, Longgang Yu, Yan Jiang

引用次数: 0

A rare case of disseminated amebiasis in a patient on biologic therapy for chronic rhinosinusitis 一例因慢性鼻炎接受生物治疗的患者感染播散性阿米巴病的罕见病例。

IF 7.2 2区医学

International Forum of Allergy & Rhinology Pub Date : 2024-10-23 DOI: 10.1002/alr.23473

Ariel Omiunu MD, Lindsey Brown PA-C, Darpan Kayastha MD, R. Peter Manes MD

引用次数: 0

Temperature-controlled radiofrequency treatment of the nasal valve in nasal airway obstruction patients with septal deviation. 对鼻中隔偏曲的鼻气道阻塞患者进行鼻瓣膜温控射频治疗。

IF 7.2 2区医学

International Forum of Allergy & Rhinology Pub Date : 2024-10-18 DOI: 10.1002/alr.23472

Dennis M Tang, Philip G Chen, Arthur W Wu, William C Yao

引用次数: 0