Integrative Medicine Research最新文献

{"title":"Exploring the potential transdiagnostic treatment effects of Chinese herbal medicine and acupuncture on insomnia disorder comorbid with chronic pain: A scoping review","authors":"Yan Ling Kwok ,&nbsp;Ran Wang ,&nbsp;Hiu To Tang ,&nbsp;Siyu Chen ,&nbsp;Albert Yeung ,&nbsp;Zhaoxiang Bian ,&nbsp;Danny J. Yu","doi":"10.1016/j.imr.2025.101208","DOIUrl":"10.1016/j.imr.2025.101208","url":null,"abstract":"<div><h3>Background</h3><div>Over 20 % of adults with insomnia disorder also experience chronic pain, termed insomnia disorder comorbid with chronic pain (ICCP), increasing risks for physical and mental diseases. Current treatments like cognitive behavioral therapy for insomnia show inconsistent pain relief, and non-opioid analgesics may exacerbate insomnia, underscoring the need for alternative approaches. Chinese herbal medicine (CHM) and acupuncture, guided by traditional Chinese medicine, may offer transdiagnostic benefits for ICCP, but a comprehensive review is lacking. This scoping review evaluates their therapeutic effects and mechanisms for ICCP.</div></div><div><h3>Methods</h3><div>PubMed, Wanfang, ClinicalTrials.gov and Google Scholar were searched up to December 31, 2024, for randomized controlled trials (RCTs) involving adults (≥18 years) with Diagnostic and Statistical Manual of Mental Disorders, Fifth Edition-defined insomnia and the International Association for the Study of Pain-defined chronic pain, treated with CHM or acupuncture. Effect sizes (modified Cohen’s d) assessed efficacy of interventions, and the Cochrane Risk of Bias 2 tool evaluated the risk of bias.</div></div><div><h3>Results</h3><div>Six RCTs (487 participants) were included. CHM (modified Guipi decoction) showed medium to large effects for insomnia (<em>d</em> = 0.70–1.17) and pain (<em>d</em> = 0.67–1.42) versus diazepam/estazolam. Acupuncture had medium to large effects for insomnia (<em>d</em> = 0.64–0.99) and pain (<em>d</em> = 0.80–1.33) compared to treatment as usual. Combined CHM (Da Huoluo capsules) and acupuncture showed medium effects (<em>d</em> = 0.72 for insomnia; <em>d</em> = 0.57 for pain) versus multi-medications/traction. Most studies (83.33 %) had high risk of bias.</div></div><div><h3>Conclusion</h3><div>CHM and acupuncture show promise for ICCP management, but high risk of bias warrants cautious interpretation and further high-quality RCTs.</div></div>","PeriodicalId":13644,"journal":{"name":"Integrative Medicine Research","volume":"14 4","pages":"Article 101208"},"PeriodicalIF":3.0,"publicationDate":"2025-07-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144866465","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Modified Saengmaeksan, an herbal formula containing six herbs, improves hypertension through RhoA/Rho kinase-mediated vasorelaxation","authors":"Young Mi Seok ,&nbsp;Hye-Lin Kim ,&nbsp;Hyo In Kim ,&nbsp;Hobin Moon ,&nbsp;Yohan Han ,&nbsp;Eun Sang Cho ,&nbsp;Hyun Hee Leem ,&nbsp;Hyo Jung Kim ,&nbsp;Sujin Shin ,&nbsp;Se-Jin Kim ,&nbsp;Jin Ki Jung ,&nbsp;Wei Huang ,&nbsp;Kyung Oh Jung ,&nbsp;Doo Suk Lee ,&nbsp;Sung Giu Jin ,&nbsp;Hyunwoo Kim ,&nbsp;Changsop Yang ,&nbsp;Kyungjin Lee ,&nbsp;Jinbong Park","doi":"10.1016/j.imr.2025.101207","DOIUrl":"10.1016/j.imr.2025.101207","url":null,"abstract":"<div><h3>Background</h3><div>Saengmaeksan is a traditional herbal formula used in Korean medicine. We composed a modified formula based on Saengmaeksan (mSMS) with Puerariae Radix, Platycodonis Radix, Liriopis seu Ophiopogonis Tuber, Schisandrae Fructus, Coicis Semen, and Dioscoreae Rhizoma to investigate its in vivo and ex vivo antihypertensive effects and underlying mechanisms.</div></div><div><h3>Methods</h3><div>The antihypertensive efficacy of mSMS was assessed using <span>l</span>-NAME-induced hypertensive mice and spontaneously hypertensive rats (SHR). The animals were treated with mSMS, and blood pressure was monitored weekly. Vascular effects were evaluated through organ bath studies and aortic histology, while oxidative stress was assessed using DCF-DA staining. Renal protection was examined via H&amp;E and immunofluorescence staining for AT1R expression. The molecular mechanisms were explored through Western blot analysis and GTP-RhoA assays.</div></div><div><h3>Results</h3><div>mSMS significantly reduced systolic and diastolic blood pressure in both hypertensive models, with the ethanol extract demonstrating superior efficacy. mSMS inhibited the RhoA/Rho kinase pathway, leading to reduced phosphorylation of MYPT1 and CPI17, and improved vascular relaxation. Additionally, mSMS attenuated aortic wall thickening, oxidative stress, and renal damage, with a marked decrease in AT1R expression in the kidneys.</div></div><div><h3>Conclusions</h3><div>mSMS exhibits potent antihypertensive effects through the inhibition of the RhoA/Rho-kinase pathway, reduction of vascular remodeling, oxidative stress, and renal protection. These findings support the potential of mSMS as a novel therapeutic agent for hypertension, offering a multi-targeted approach with fewer side effects compared to conventional therapies. Further clinical studies are required to confirm its clinical efficacy.</div></div>","PeriodicalId":13644,"journal":{"name":"Integrative Medicine Research","volume":"14 4","pages":"Article 101207"},"PeriodicalIF":3.0,"publicationDate":"2025-07-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144866392","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"The efficacy and safety of multiple acupuncture therapies in primary insomnia: A Bayesian network meta-analysis","authors":"Liguo Liu ,&nbsp;Yiming Chen ,&nbsp;Minne Tian ,&nbsp;Zhennan Wu ,&nbsp;Peiming Zhang ,&nbsp;Tiankang Zhang ,&nbsp;Jinsong Yang ,&nbsp;Haotian Qu ,&nbsp;Zhiyong Fan ,&nbsp;Shan Wu ,&nbsp;Liming Lu ,&nbsp;Yu Kui","doi":"10.1016/j.imr.2025.101206","DOIUrl":"10.1016/j.imr.2025.101206","url":null,"abstract":"<div><h3>Background</h3><div>Acupuncture (AT) therapy is an effective treatment for primary insomnia. However, no comprehensive study has compared and evaluated the efficacy and safety of multiple AT therapies and hypnotics.</div></div><div><h3>Methods</h3><div>We searched eight databases from inception to July 2024 for randomized controlled trials (RCTs) of AT treatment for primary insomnia, including PubMed, Web of Science, Embase, Cochrane Library, Wanfang database, China National Knowledge Infrastructure database, and VIP Chinese Science and Technique Journals database. After screening, the Pittsburgh Sleep Quality Index (PSQI) score and clinical effectiveness rate were extracted from the included RCTs as outcome measures. We performed network meta-analysis using the Stata and R software.</div></div><div><h3>Results</h3><div>Sixty-four RCTs involving 4443 patients were included in this study. Multiple AT therapies had better efficacy in improving PSQI scores than hypnotics, with AT combined with moxibustion (MOX) and AT combined with auriculotherapy (AU) as the best interventions. Regarding clinical effectiveness, acupoint catgut embedding (ACE) had the greatest potential of being the best intervention, and no serious adverse events related to AT therapies were observed in any of the studies.</div></div><div><h3>Conclusion</h3><div>This review suggests that most AT therapies improve sleep indicators and have good clinical efficacy compared to hypnotics, especially AT combined with AU, AT combined with MOX, and ACE. The safety of AT therapies is reliable; however, the overall quality of the included trials was low, and higher-quality RCTs are required to provide sufficient evidence.</div></div><div><h3>Protocol registration</h3><div>PROSPERO, CRD42017067402.</div></div>","PeriodicalId":13644,"journal":{"name":"Integrative Medicine Research","volume":"14 4","pages":"Article 101206"},"PeriodicalIF":3.0,"publicationDate":"2025-07-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145019895","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Development of core outcome set for healthy aging treatment in primary care settings","authors":"Soobin Jang ,&nbsp;Hyein Jeong ,&nbsp;Jungi Park ,&nbsp;Mi Mi Ko ,&nbsp;Jeeyoun Jung","doi":"10.1016/j.imr.2025.101205","DOIUrl":"10.1016/j.imr.2025.101205","url":null,"abstract":"<div><h3>Background</h3><div>Healthy aging is a global public health priority, with increasing interest in the promotion of functional ability and well-being among older adults. South Korea’s rapidly aging population highlights the need for standardized evaluation tools for interventions. This study aimed to develop a Core Outcome Set (COS) for healthy aging treatment in primary care.</div></div><div><h3>Methods</h3><div>The COS was developed following the COS-STAD guidelines and through a multiphase process, including a literature review and a modified Delphi consensus. A project management group (PMG) reviewed studies related to health promotion programs and generated an initial list of outcomes. This list was refined through two rounds of Delphi surveys involving 16 experts. Consensus was assessed using content validity ratio, degree of consensus, and convergence.</div></div><div><h3>Results</h3><div>Twenty-six studies informed the initial outcome list, resulting in 24 outcomes for the Delphi evaluation. Two Delphi rounds and a final review by the PMG established a COS comprising 12 outcomes. These included EQ-5D, Geriatric Depression Scale, Instrumental Activities of Daily Living, body weight, blood pressure, blood glucose, blood lipids, liver function, kidney function, Korean Frailty Index, Self-rated Health, and Kidney-Deficiency Score.</div></div><div><h3>Conclusions</h3><div>The COS provides a standardized set of outcomes for evaluating healthy aging interventions in primary care. Its application in primary care and health promotion programs may enhance comparability across studies and support evidence-based decision making. Future revisions are recommended based on clinical applications and emerging research findings.</div></div>","PeriodicalId":13644,"journal":{"name":"Integrative Medicine Research","volume":"14 4","pages":"Article 101205"},"PeriodicalIF":3.0,"publicationDate":"2025-07-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144860466","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Effectiveness and safety of combining pharmacopuncture therapy and acupotomy for treating patients with degenerative lumbar spinal stenosis: A pragmatic, assessor-blinded, randomized, controlled trial","authors":"Jihun Kim ,&nbsp;Chang-Hyun Han ,&nbsp;Taewook Lee ,&nbsp;Sookwang An ,&nbsp;Changsop Yang ,&nbsp;Young Eun Choi ,&nbsp;Byoung-Kab Kang ,&nbsp;Yoona Oh ,&nbsp;Kun Hyung Kim ,&nbsp;Gi Young Yang ,&nbsp;Eunseok Kim","doi":"10.1016/j.imr.2025.101204","DOIUrl":"10.1016/j.imr.2025.101204","url":null,"abstract":"<div><h3>Background</h3><div>In the clinical practice of Korean Medicine, pharmacopuncture therapy and acupotomy (PA) are being increasingly explored as potential treatment options for degenerative lumbar spinal stenosis (LSS). In this study, we aimed to evaluate the effectiveness and safety of combining PA with conventional Korean Medicine treatment (CKMT) in patients with degenerative LSS.</div></div><div><h3>Methods</h3><div>A pragmatic, assessor-blinded, randomized controlled trial was conducted with 104 participants aged 40–75 years diagnosed with degenerative LSS. The participants were randomly assigned to either the CKMT+PA or CKMT alone groups over a 6-week period. The primary outcome was the mean change in the visual analog scale (VAS) for pain/discomfort. Secondary outcomes included clinically important differences (CID), Zurich Claudication Questionnaire, self-reported maximum walking distance, Roland-Morris Disability Questionnaire, EuroQol 5-dimension 5-level questionnaire, and patients’ global impression of change. The adverse events (AEs) were assessed at each visit.</div></div><div><h3>Results</h3><div>The CKMT+PA group showed significant improvements in VAS scores compared to the CKMT group at 6 weeks (adjusted mean difference: 20.26; 95 % confidence interval: 13.79–26.72, <em>p</em> &lt; 0.0001), and a higher proportion of patients in the CKMT+PA group achieved the minimal CID in pain reduction. These improvements persisted at weeks 10 and 14. Superior results were also observed with respect to secondary outcomes in the CKMT+PA group compared to the CKMT group across all time points. CKMT showed no AEs, while mild AEs occurred in 1.7 % of bee venom and 2.2 % of acupotomy sessions.</div></div><div><h3>Conclusion</h3><div>Compared to CKMT alone, CKMT+PA offers significant improvements in pain relief, functional capacity, and quality of life in patients with degenerative LSS.</div></div><div><h3>Trial registration</h3><div>Clinical Research Information Service (CRIS) registry, KCT0008557.</div></div>","PeriodicalId":13644,"journal":{"name":"Integrative Medicine Research","volume":"15 1","pages":"Article 101204"},"PeriodicalIF":3.0,"publicationDate":"2025-07-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144903993","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"From sound to science: Enhancing transparency in music-based therapeutic research","authors":"Hyun Ju Chong","doi":"10.1016/j.imr.2025.101203","DOIUrl":"10.1016/j.imr.2025.101203","url":null,"abstract":"","PeriodicalId":13644,"journal":{"name":"Integrative Medicine Research","volume":"14 3","pages":"Article 101203"},"PeriodicalIF":3.0,"publicationDate":"2025-07-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144810287","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Reporting guidelines for music-based interventions checklist: Explanation and elaboration guide","authors":"Sheri L. Robb ,&nbsp;K. Maya Story ,&nbsp;Elizabeth Harman ,&nbsp;Debra S. Burns ,&nbsp;Joke Bradt ,&nbsp;Emmeline Edwards ,&nbsp;Tasha L. Golden ,&nbsp;Christian Gold ,&nbsp;John R. Iversen ,&nbsp;Assal Habibi ,&nbsp;Julene K. Johnson ,&nbsp;Miriam Lense ,&nbsp;Susan M. Perkins ,&nbsp;Stacey Springs","doi":"10.1016/j.imr.2025.101200","DOIUrl":"10.1016/j.imr.2025.101200","url":null,"abstract":"<div><h3>Background</h3><div>Detailed intervention reporting is essential to interpretation, replication, and eventual translation of music-based interventions (MBIs) into practice. Despite availability of <em>Reporting Guidelines for Music-based Interventions</em> (RG-MBI, published 2011), multiple reviews reveal sustained problems with reporting quality and consistency. To address this, we convened an interdisciplinary expert panel to update and improve the utility and validity of the existing guidelines using a rigorous Delphi approach. The resulting updated checklist includes 12-items across eight areas considered essential to ensure transparent reporting of MBIs.</div></div><div><h3>Methods</h3><div>The purpose of this explanation and elaboration document is to facilitate consistent understanding, use, and dissemination of the revised RG-MBI. Members of the interdisciplinary expert panel collaborated to create the resulting guidance statement.</div></div><div><h3>Results</h3><div>This guidance statement offers: (1) the scope and intended use of the RG-MBI, (2) an explanation for each checklist item, with examples from published studies, and (3) two published studies with annotations indicating where the authors reported each checklist item.</div></div><div><h3>Conclusion</h3><div>Broader uptake of the RG-MBIs by study authors, editors, and peer reviewers will lead to better reporting of MBI trials, and in turn facilitate greater replication of research, improve cross-study comparisons and meta-analyses, and increase implementation of findings.</div></div>","PeriodicalId":13644,"journal":{"name":"Integrative Medicine Research","volume":"14 3","pages":"Article 101200"},"PeriodicalIF":3.0,"publicationDate":"2025-07-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144831556","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Traditional Korean and Western medicine use after industrial accidents: A hurdle model analysis","authors":"Sungmin Park ,&nbsp;Bo-Hyoung Jang","doi":"10.1016/j.imr.2025.101202","DOIUrl":"10.1016/j.imr.2025.101202","url":null,"abstract":"<div><h3>Background</h3><div>The number of injured workers using Traditional Korean Medicine (KM) soared from 752 in 2013 to 10,273 in 2023, yet this trend remains underexplored. This cross-sectional study examined the frequency and factors linked to KM and Western Medicine (WM) use among injured workers.</div></div><div><h3>Methods</h3><div>Data from 6,985 participants in the 2018 and 2023 waves of the Panel Study of Workers’ Compensation Insurance (PSWCI) were analyzed. A hurdle model assessed outpatient visits: logistic regression for the probability of use and negative binomial regression for visit intensity. Demographic, socioeconomic, and clinical factors were included as covariates.</div></div><div><h3>Results</h3><div>Of 6,985 participants, 182 used KM, 5,970 used WM, and 833 reported no outpatient visits. Having private medical insurance and lower limb injuries showed higher Total Marginal Effects (TME) of both KM and WM utilization. KM use showed higher TMEs among females and those with occupational diseases but lower TMEs for injuries to other body regions. Higher WM utilization was linked to workers with disabilities, hypertension, chronic conditions, and extended rehabilitation, while the 2023 cohort, higher education and income, alcohol consumption, and re-employment were linked to lower WM use.</div></div><div><h3>Conclusions</h3><div>Between 2018 and 2023, adjusted KM utilization remained unchanged, whereas WM visits declined. KM use was positively linked to being female and having occupational diseases. WM visits tended to rise with greater medical severity yet decreased as socioeconomic conditions improved. Still, the rise in total KM claims under WCI indicates a growing demand for conservative, pain-relieving musculoskeletal care.</div></div>","PeriodicalId":13644,"journal":{"name":"Integrative Medicine Research","volume":"15 1","pages":"Article 101202"},"PeriodicalIF":3.0,"publicationDate":"2025-07-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144908398","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Effects of LIPOSA-T pharmacopuncture on localized fat as a fat dissolving injection via regulation of fat metabolism","authors":"Mi Hye Kim ,&nbsp;Seong Chul Jin ,&nbsp;Woong Mo Yang","doi":"10.1016/j.imr.2025.101201","DOIUrl":"10.1016/j.imr.2025.101201","url":null,"abstract":"<div><h3>Background</h3><div>Excessive fat deposition in localized adiposity is known to induce severe medical diseases as well as aesthetic problems. Of late, LIPOSA-T pharmacopuncture, a new herbal pharmacopuncture consisting of the cortex of <em>Morus alba</em> and bark of <em>Magnolia officinalis</em>, is developed as a non-surgical injection for dissolving localized fat deposits.</div></div><div><h3>Methods</h3><div>The network pharmacology analysis was carried out with the target gene sets of constituents of <em>M. alba</em> and <em>M. officinalis</em>. Male C57BL/6 J mice were induced obesity and injected LIPOSA-T pharmacopuncture into inguinal fat pad. The fat weight and size were analyzed using dual energy X-ray absorptiometry.</div></div><div><h3>Results</h3><div>The possible pathways and mechanism of action of LIPOSA-T were found to be mainly related to the fatty acid biosynthesis, glycolysis and glycogenesis in KEGG Pathways database. Subcutaneous injection of the LIPOSA-T pharmacopuncture significantly reduced the inguinal fat tissues weight and enlarged adipocyte size. In addition, the phosphorylated IRS with the PEPCK and G6p expressions were increased by the LIPOSA-T injection. Following the increase of AMPK expression, the fatty acid synthesis enzyme and lipolytic enzymes were regulated by the LIPOSA-T.</div></div><div><h3>Conclusions</h3><div>Taken together, LIPOSA-T exerted the catabolic effects on fat deposition in obesity by regulating the glucose production, lipid synthesis and TAG hydrolysis in consistent with the prediction results. Based on the findings, LIPOSA-T pharmacopuncture is expected to be a dissolving injection for localized fat.</div></div>","PeriodicalId":13644,"journal":{"name":"Integrative Medicine Research","volume":"14 4","pages":"Article 101201"},"PeriodicalIF":3.0,"publicationDate":"2025-07-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144852718","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Reporting guidelines for music-based interventions: An update and validation study","authors":"Sheri L Robb ,&nbsp;Stacey Springs ,&nbsp;Emmeline Edwards ,&nbsp;Tasha L. Golden ,&nbsp;Julene K. Johnson ,&nbsp;Debra S. Burns ,&nbsp;Melita Belgrave ,&nbsp;Joke Bradt ,&nbsp;Christian Gold ,&nbsp;Assal Habibi ,&nbsp;John R. Iversen ,&nbsp;Miriam Lense ,&nbsp;Jessica A. MacLean ,&nbsp;Susan M. Perkins","doi":"10.1016/j.imr.2025.101199","DOIUrl":"10.1016/j.imr.2025.101199","url":null,"abstract":"<div><h3>Background</h3><div>Detailed intervention reporting is essential to interpretation, replication, and translation of music-based interventions (MBIs). The 2011 <em>Reporting Guidelines for Music-Based Interventions</em> were developed to improve transparency and reporting quality of published research; however, problems with reporting quality persist.</div></div><div><h3>Methods</h3><div>The purpose of this study was to update and validate the 2011 reporting guidelines using rigorous Delphi approach that involved an interdisciplinary group of MBI researchers; and to develop an explanation and elaboration guidance statement to support dissemination and usage. We followed the methodological framework for developing reporting guidelines recommended by the EQUATOR Network and guidance recommendations for developing health research reporting guidelines. Our three-stage process included: (1) an initial field scan, (2) a consensus process using Delphi surveys (two rounds) and Expert Panel meetings, and (3) development and dissemination of an explanation and elaboration document.</div></div><div><h3>Results</h3><div>First-Round survey findings revealed that the original checklist items were capturing content that investigators deemed essential to MBI reporting; however, it also revealed problems with item wording and terminology. Subsequent Expert Panel meetings and the Second-Round survey centered on reaching consensus for item language. The revised RG-MBI checklist has a total of 12-items that pertain to eight different components of MBI interventions including name, theory/scientific rationale, content, interventionist, individual/group, setting, delivery schedule, and treatment fidelity.</div></div><div><h3>Conclusion</h3><div>We recommend that authors, journal editors, and reviewers use the RG-MBI guidelines, in conjunction with methods-based guidelines (e.g., CONSORT) to accelerate and improve the scientific rigor of MBI research.</div></div>","PeriodicalId":13644,"journal":{"name":"Integrative Medicine Research","volume":"14 3","pages":"Article 101199"},"PeriodicalIF":3.0,"publicationDate":"2025-07-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144724025","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}