Innovation in AgingPub Date : 2025-07-16eCollection Date: 2025-08-01DOI: 10.1093/geroni/igaf079
Nan Jiang, Ke Chen, Yexuan Xiao, Vivian W Lou
{"title":"Impact of spousal congruence on emotional perception on solitude in older couples: a response surface analysis.","authors":"Nan Jiang, Ke Chen, Yexuan Xiao, Vivian W Lou","doi":"10.1093/geroni/igaf079","DOIUrl":"10.1093/geroni/igaf079","url":null,"abstract":"<p><strong>Background and objectives: </strong>Solitude is a common yet nuanced experience in later life, but how older couples jointly experience and perceive solitude remains underexplored. This study examines the influence of congruent and incongruent emotional states between spouses on their subjective experience of solitude, with particular attention to potential gender differences. Understanding this relational dynamic may provide insights to support emotional well-being among aging couples.</p><p><strong>Research design and methods: </strong>A total of 73 older couples aged 60 to 100 years in Hong Kong SAR, China, participated in this study. Participants completed online questionnaires and Ecological Momentary Assessments (EMA) twice daily for 14 days. Polynomial longitudinal regression models and Response Surface Analysis (RSA) were employed to explore the relationship between congruence and discrepancy in positive affect (PA) and negative affect (NA) between spouses and their perceived solitude.</p><p><strong>Results: </strong>Significant associations were found between spousal congruence in NA and perceived solitude for both genders, with women showing a more pronounced impact when perceiving greater NA than their partners (women: <i>a</i> <sub>1</sub> = 0.389, <i>p</i> < .001; <i>a</i> <sub>2</sub> = 0.360, <i>p</i> <.001; <i>a</i> <sub>3</sub> = 0.559, <i>p</i> <.001; men: <i>a</i> <sub>1</sub> = 0.494, <i>p</i> < .001; <i>a</i> <sub>2</sub> = 0.333, <i>p</i> <.001; <i>a</i> <sub>3</sub> = 0.452, <i>p</i> < .001). For PA, women experienced increased solitude when perceiving greater PA than their partners (<i>a</i> <sub>1</sub> = -0.285, <i>p</i> < .001; <i>a</i> <sub>4</sub> = 0.429, <i>p</i> < .001), whereas men's solitude was affected by both congruence and incongruence in PA (<i>a</i> <sub>1</sub> = -0.224, <i>p</i> < .001; <i>a</i> <sub>3</sub> = -0.228, <i>p</i> < .001).</p><p><strong>Discussions and implications: </strong>Spousal emotional congruence significantly influences perceptions of solitude, differing by gender. Interventions should target emotional communication skills, couple-based therapy, and support groups to enhance relational dynamics, reduce loneliness, and promote emotional well-being in older adults navigating solitude together.</p>","PeriodicalId":13596,"journal":{"name":"Innovation in Aging","volume":"9 8","pages":"igaf079"},"PeriodicalIF":4.3,"publicationDate":"2025-07-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12449250/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145113030","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Innovation in AgingPub Date : 2025-07-10eCollection Date: 2025-07-01DOI: 10.1093/geroni/igaf061
Michelle Putnam
{"title":"Increasing submission and dialogue opportunities within <i>Innovation in Aging</i>.","authors":"Michelle Putnam","doi":"10.1093/geroni/igaf061","DOIUrl":"https://doi.org/10.1093/geroni/igaf061","url":null,"abstract":"","PeriodicalId":13596,"journal":{"name":"Innovation in Aging","volume":"9 7","pages":"igaf061"},"PeriodicalIF":4.9,"publicationDate":"2025-07-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12242374/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144626220","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Association between mental work and biological aging: the mediating role of visceral adiposity index.","authors":"Kangnan Zhang, Rongdi Xu, Yuhe Liu, Wenqian Wu, Yong Zhou","doi":"10.1093/geroni/igaf077","DOIUrl":"10.1093/geroni/igaf077","url":null,"abstract":"<p><strong>Background and objectives: </strong>This study aimed to investigate the relationship between mental work, work intensity, and accelerated biological aging, focusing on the mediating role of the Visceral Adiposity Index (VAI).</p><p><strong>Research design and methods: </strong>In this cross-sectional study, data were collected from the Kailuan physical activity cohorts in the Asia-Pacific region. Biological aging was assessed using PhenoAge and Klemera-Doubal method age (KDMAge) acceleration. Multivariable linear regression models examined the link between mental work and biological aging, while mediation analysis assessed the role of VAI.</p><p><strong>Results: </strong>Among 3,933 participants (mean age 56.4 years; 55.6% male), mental workers showed greater biological age (BA) acceleration: KDMAge acceleration increased by 1.52 years (<i>p</i> for trend = .04) and PhenoAge by 1.46 years (<i>p</i> for trend < .001) compared to manual workers, after adjusting for age and sex. In mental workers, high labor intensity was associated with greater BA acceleration: KDMAge β = 0.40, 95% CI [0.10-0.65]; PhenoAge β = 0.51, 95% CI [0.10-1.38]. In manual workers, high labor intensity also correlated with increased BA acceleration: KDMAge β = 1.53, 95% CI [0.91-2.12]; PhenoAge β = 1.32, 95% CI [0.37-2.26]. Mediation analysis showed that VAI mediated 9.8% of the mental work-PhenoAge relationship and 20.9% of the KDMAge relationship.</p><p><strong>Discussion and implications: </strong>Mental work is associated with accelerated biological aging. These results highlight the importance of interventions targeting work intensity and metabolic health to reduce age-related disease burdens.</p>","PeriodicalId":13596,"journal":{"name":"Innovation in Aging","volume":"9 8","pages":"igaf077"},"PeriodicalIF":4.3,"publicationDate":"2025-07-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12409274/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145015114","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Innovation in AgingPub Date : 2025-07-04eCollection Date: 2025-07-01DOI: 10.1093/geroni/igaf075
Kelseanne Breder, Van Yu
{"title":"Opioid use disorder, pain, and cognitive impairment in older adults who have experienced homelessness.","authors":"Kelseanne Breder, Van Yu","doi":"10.1093/geroni/igaf075","DOIUrl":"10.1093/geroni/igaf075","url":null,"abstract":"<p><strong>Background and objectives: </strong>The population of older adults with lived experience of homelessness in the United States is growing. Homelessness is associated with accelerated aging and opioid misuse. Older adults who have experienced homelessness suffer from greater functional impairment than nonhomeless older adults. Opioid misuse may catalyze functional impairment in this population, yet little is known about the prevalence of opioid use disorder (OUD) among currently and formerly homeless older adults. We report findings about the prevalence of OUD and functionality that we hope will spur future research about longevity and OUD in this population.</p><p><strong>Research design and methods: </strong>Using a secondary analysis of data collected in New York City through electronic medical records, we examined 253 patients who met three inclusion criteria: (a) aged 50 years and older, (b) history of homelessness, and (c) received community-based medical services. We summarize the prevalence of OUD in our cohort and present descriptive statistics about pain and cognitive function for a small subset measured by the Pain Enjoyment of Life and General Activity (PEG) and Mini-Cog scales.</p><p><strong>Results: </strong>Twelve percent (<i>n</i> = 31) had OUD diagnoses (age range = 50-81; mean age = 65; median age = 65; female = 11; and receiving agonist therapy = 5). Of those, 18 completed Mini-Cog; two showed clinically important cognitive impairment; 14 completed PEG; and eight reported moderate to severe pain.</p><p><strong>Discussion and implications: </strong>Our report is among the first to describe OUD among older adults who have experienced homelessness. Currently and formerly homeless older adults with OUD are younger, on average, and more likely to be female, than those without OUD. They are more likely to report pain but less likely to exhibit cognitive impairment. Possible explanations for these observations include care engagement, untreated pain, and a survivor effect wherein older adults with OUD who survive homelessness may have traits that protect them from cognitive decline and fatal overdose.</p>","PeriodicalId":13596,"journal":{"name":"Innovation in Aging","volume":"9 7","pages":"igaf075"},"PeriodicalIF":4.3,"publicationDate":"2025-07-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12373114/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144952436","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Innovation in AgingPub Date : 2025-07-01eCollection Date: 2025-01-01DOI: 10.1093/geroni/igaf047
Iris Blotenberg, Lina Jeran, Francisca S Rodriguez, Bernhard Michalowsky, Moritz Platen, Stefan Teipel, Wolfgang Hoffmann, Jochen René Thyrian
{"title":"The Role of Social Support for Depressive Symptoms in Dementia: A Four-Year Longitudinal Study.","authors":"Iris Blotenberg, Lina Jeran, Francisca S Rodriguez, Bernhard Michalowsky, Moritz Platen, Stefan Teipel, Wolfgang Hoffmann, Jochen René Thyrian","doi":"10.1093/geroni/igaf047","DOIUrl":"10.1093/geroni/igaf047","url":null,"abstract":"<p><strong>Background and objectives: </strong>Depressive symptoms are common in people with dementia, significantly reducing well-being and potentially exacerbating dementia symptoms. The objective of the present study was to investigate the role of support from the social environment for depressive symptoms in people with dementia over a 4-year period.</p><p><strong>Research design and methods: </strong>We used data from a cohort of 334 community-dwelling people with dementia (<i>M</i> <sub>age</sub> = 80.2, 59.3% female) who were interviewed annually in their homes by specially qualified nurses. We used multilevel growth curve models with random intercepts and slopes to model depressive symptoms over time. We modeled both the role of between-person differences and the role of within-person changes in social support for depressive symptoms.</p><p><strong>Results: </strong>At the beginning of the study, 13.8% of people with dementia reported mild to severe depressive symptoms. People with more social support showed fewer depressive symptoms overall over the 4-year period (% change per point on a scale from 22 to 110: -1.2, 95% CI: -1.8, -0.4). In addition, a decline in a person's social support was associated with more depressive symptoms (% change: -0.9, 95% CI: -1.7, -0.2). These effects were stable even after controlling for sociodemographic (age, sex, education) and clinical factors (cognitive and functional status, comorbidities).</p><p><strong>Discussion and implications: </strong>The social environment plays an important role in depressive symptoms in people with dementia-beyond clinical factors like cognitive and functional abilities. Improving support from the social environment could be a lever for alleviating depressive symptoms. In the care of people with dementia, not only medical needs but also psychosocial needs should come to the forefront.</p>","PeriodicalId":13596,"journal":{"name":"Innovation in Aging","volume":"9 6","pages":"igaf047"},"PeriodicalIF":4.9,"publicationDate":"2025-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12210947/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144540068","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Innovation in AgingPub Date : 2025-07-01eCollection Date: 2025-08-01DOI: 10.1093/geroni/igaf074
Laura N Gitlin, Katherine B Marx, David L Roth, Keith Anderson, Holly Dabelko-Schoeny, Danny Scerpella, Lauren J Parker, Sokha Koeuth, Joseph E Gaugler
{"title":"Fidelity matters: implementing ADS Plus, an evidence-based program, in multiple adult day service sites.","authors":"Laura N Gitlin, Katherine B Marx, David L Roth, Keith Anderson, Holly Dabelko-Schoeny, Danny Scerpella, Lauren J Parker, Sokha Koeuth, Joseph E Gaugler","doi":"10.1093/geroni/igaf074","DOIUrl":"10.1093/geroni/igaf074","url":null,"abstract":"<p><strong>Background and objectives: </strong>In a cluster randomized trial, we found that augmenting adult day services (ADS) with a multicomponent caregiver support program, ADS Plus, reduced caregiver depressive symptoms and increased ADS use. Unclear is whether the program was implemented with fidelity across sites and the relationship of fidelity to site characteristics and caregiver outcomes.</p><p><strong>Research design and methods: </strong>Sixteen ADS sites were randomly assigned to ADS Plus (<i>n</i> = 102 caregivers), which offered dementia education, referrals/linkages, validation/support, and strategies for self-care and caregiver-identified challenges. Sites were categorized with high, moderate, or low fidelity based on the number of caregivers enrolled (delivery), care challenges addressed, and prescriptions (strategies) provided (receipt). We examined staff documentation of delivery, receipt, and enactment characteristics, the relationship of fidelity to site characteristics, and caregiver outcomes (depressive symptoms, stress) collected by interviewers 3, 6, and 12 months postbaseline.</p><p><strong>Results: </strong>Of 102 caregivers, 79.5% were in high (<i>n</i> = 58, 56.9%) or moderate (<i>n</i> = 23, 22.6%), versus 20.6% (<i>n</i> = 21) in low-fidelity sites. High/moderate versus low-fidelity sites delivered more sessions and spent less preparatory time. Caregiver receptivity to sessions was high across all sites. Caregivers with enactment data (<i>n</i> = 43) reported reduced difficulties and upset in high/moderate fidelity sites, and enhanced confidence managing care challenges in high-fidelity sites (<i>p</i> < .0001). Sites with higher percentages of White, non-Hispanic families (<i>p</i> = .006) and dementia clients (<i>p</i> = .004) had better fidelity. At three and 12 months but not at 6 months, caregivers in high/moderate fidelity sites had greater reductions in depressive symptoms and stress (<i>p</i><.05) compared to those in low-fidelity sites.</p><p><strong>Discussion and implications: </strong>Most caregivers received ADS Plus with moderate to high fidelity. High/moderate fidelity sites delivered more sessions to more caregivers with substantially stronger caregiver benefits. As fidelity varied by site characteristics, adaptations to staff training and the program appear needed for low-fidelity sites.</p><p><strong>Clinical trial registration number: </strong>NCT02927821.</p>","PeriodicalId":13596,"journal":{"name":"Innovation in Aging","volume":"9 8","pages":"igaf074"},"PeriodicalIF":4.3,"publicationDate":"2025-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12448453/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145113011","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Jiaming Liang, Maria P Aranda, Yuri Jang, Kathleen H Wilber
{"title":"The longitudinal impacts of secondary caregiver networks on primary caregiver's social isolation and depression.","authors":"Jiaming Liang, Maria P Aranda, Yuri Jang, Kathleen H Wilber","doi":"10.1093/geroni/igaf073","DOIUrl":"10.1093/geroni/igaf073","url":null,"abstract":"<p><strong>Background and objectives: </strong>Caregiving for older adults often leads to increased social isolation and depression among primary caregivers. Secondary caregiver networks (SCNs) may provide crucial support, potentially mitigating these adverse outcomes. This study aimed to identify the SCN support patterns and examine their impacts on primary caregivers' social isolation and depression over 2 years, as well as potential differences in the associations by gender and race.</p><p><strong>Research design and methods: </strong>Data from the 2015 and 2017 National Study of Caregiving (NSOC) and National Health and Aging Trends Study (NHATS) were used. Latent profile analysis identified distinct SCN support patterns. Mixed-effects models assessed associations between SCN patterns, social isolation, and depression.</p><p><strong>Results: </strong>Among 782 primary and 1,003 secondary caregivers, three SCN support patterns (low, medium, and high) were identified. Higher SCN support was associated with lower social isolation at baseline, but increased social isolation over time. Depression increased over time, but was not associated with SCN support. No significant gender and racial differences were found.</p><p><strong>Discussion and implications: </strong>While SCN support initially reduces social isolation among primary caregivers, its effectiveness diminishes over time. The study highlights the necessity for continuous social and mental health support for primary caregivers, regardless of SCN support level, to better address the evolving demands of caregiving.</p>","PeriodicalId":13596,"journal":{"name":"Innovation in Aging","volume":"9 7","pages":"igaf073"},"PeriodicalIF":4.3,"publicationDate":"2025-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12393903/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144952659","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Innovation in AgingPub Date : 2025-06-30eCollection Date: 2025-07-01DOI: 10.1093/geroni/igaf071
Shraddha A Shende, Lyndsie M Koon, Jenny L Singleton, Wendy A Rogers
{"title":"Everyday challenges and solutions for individuals aging with deafness.","authors":"Shraddha A Shende, Lyndsie M Koon, Jenny L Singleton, Wendy A Rogers","doi":"10.1093/geroni/igaf071","DOIUrl":"10.1093/geroni/igaf071","url":null,"abstract":"<p><strong>Background and objectives: </strong>Approximately 11 million people in the United States self-identify as Deaf and use American Sign Language (ASL) as their primary form of communication. Yet, little is known about the challenges and solutions in everyday activities of individuals who are <i>aging with long-term deafness</i>.</p><p><strong>Research design and methods: </strong>We used a community-engaged research approach to understand everyday challenges and solutions of 60 older ASL users who self-identified as Deaf. Semi-structured interviews were conducted in ASL to probe challenges and responses to those challenges across six everyday activity categories: Activities Within the Home; Activities Outside the home; Transportation; Managing Health; Shopping and Finances; and Basic Daily Activities.</p><p><strong>Results: </strong>Older Deaf adults shared their lived experiences and reported challenges with unreliable technology, communication, and accessibility in the context of engaging in a myriad of everyday activities. For instance, they reported that technology alerts (e.g., airport announcements) are typically auditory, and healthcare accessibility is poor due to a lack of ASL interpreters. When probed about their solutions to these everyday challenges, participants reported relying on hearing family members, using their own methods, such as self-advocating, and using devices/technologies.</p><p><strong>Discussion and implications: </strong>Everyday challenges experienced by older Deaf adults may be mitigated by improving the reliability and accessibility of technologies used by this population, as well as improving communication accessibility across various public and private settings. Including older Deaf community members in the needs assessment and design process is critical for development of technology solutions to improve engagement in everyday activities.</p>","PeriodicalId":13596,"journal":{"name":"Innovation in Aging","volume":"9 7","pages":"igaf071"},"PeriodicalIF":4.3,"publicationDate":"2025-06-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12401488/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144992436","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Innovation in AgingPub Date : 2025-06-30eCollection Date: 2025-07-01DOI: 10.1093/geroni/igaf072
Emelyn Mathot, Ali Hemadeh, Veerle Knoop, Ivan Bautmans, Carlota Lema-Arranz, Laura Lorenzo-López, Vanessa Valdiglesias, Blanca Laffon
{"title":"The effect of physical interventions in older adults on inflammatory markers (IL-6, IL-10, CRP, TNF-α): an umbrella review of systematic reviews and meta-analyses.","authors":"Emelyn Mathot, Ali Hemadeh, Veerle Knoop, Ivan Bautmans, Carlota Lema-Arranz, Laura Lorenzo-López, Vanessa Valdiglesias, Blanca Laffon","doi":"10.1093/geroni/igaf072","DOIUrl":"10.1093/geroni/igaf072","url":null,"abstract":"<p><strong>Background and objectives: </strong>The occurrence of chronic low-grade inflammation during aging, also referred to as \"<i>inflammageing</i>,\" can impair immunological homeostasis and threaten healthy ageing. Different physical exercise interventions have been proposed to tackle inflammageing. The aim of this umbrella review was to appraise current evidence from systematic reviews, with or without meta-analyses, on the effect of exercise interventions on circulating levels of inflammatory markers C-reactive protein (CRP), tumor necrosis factor alpha (TNF-α), interleukin 6 (IL-6), and the anti-inflammatory marker interleukin 10 (IL-10) in community-dwelling older adults.</p><p><strong>Research design and methods: </strong>Thirteen systematic reviews on the effects of long-term exercise on CRP, TNF-α, IL-6, and IL-10 in adults aged 60 years and older were selected from a systematic search in databases PubMed and Web of Science and were included in this umbrella review.</p><p><strong>Results: </strong>Overall, a variety of long-term exercise modalities were able to reduce levels of CRP in older adults. Moreover, most exercise interventions were also able to decrease TNF-α. Some studies showed that long-term exercise can diminish IL-6, but the results are less conclusive. The long-term effects of exercise on IL-10 were less described in the literature, with only two systematic reviews showing increases, decreases, or no effects.</p><p><strong>Discussion and implications: </strong>Results obtained in this umbrella review show that different exercise modalities can decrease circulating pro-inflammatory parameters CRP, TNF-α, and IL-6 in older adults. More research is needed to appraise the effect of exercise interventions on IL-10 in older adults.</p>","PeriodicalId":13596,"journal":{"name":"Innovation in Aging","volume":"9 7","pages":"igaf072"},"PeriodicalIF":4.3,"publicationDate":"2025-06-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12398389/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144952411","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Innovation in AgingPub Date : 2025-06-27eCollection Date: 2025-01-01DOI: 10.1093/geroni/igaf059
Chih-Hsiang Yang, Donald Hedeker, Jongwon Lee, Halle Prine, Donna Coffman, Jingkai Wei, Jonathan George Hakun
{"title":"Daily Movement Activities Are Associated With Within-Person Instability of Cognitive Function in Older Adults: Evidence From an Ambulatory Assessment Study.","authors":"Chih-Hsiang Yang, Donald Hedeker, Jongwon Lee, Halle Prine, Donna Coffman, Jingkai Wei, Jonathan George Hakun","doi":"10.1093/geroni/igaf059","DOIUrl":"10.1093/geroni/igaf059","url":null,"abstract":"<p><strong>Background and objectives: </strong>Physical inactivity and excessive sedentary time (ST) are associated with poor cognitive health in older adults. However, current literature largely relies on cross-sectional designs or in-lab cognitive assessments, which do not adequately reflect cognitive function in naturalistic settings. Further, existing studies have largely overlooked the variability or the instability in daily cognitive function, which represents a critical marker of cognitive decline. This ambulatory assessment study examined the temporal associations of daily movement behaviors with the mean levels and the variability of cognition among older adults at risk of dementia.</p><p><strong>Research design and methods: </strong>96 older adults from the community (68.3 ± 7.1 years) participated in this 14-day study. They wore an accelerometer and completed smartphone-based cognitive tests up to 4 times per day. The cognitive tests assessed both performance-based and subjective cognition. The movement behaviors collected from the accelerometers include daily light-intensity physical activity (LPA), moderate-to-vigorous physical activity (MVPA), and ST. Mixed-effects location-scale models were applied to estimate the within- and between-person associations of movement behaviors and cognitive outcomes in terms of the mean levels and the degree of variability. A total of 1,269 day-level observations were analyzed.</p><p><strong>Results: </strong>Older adults' between-person levels of daily MVPA and steps were associated with better mean cognitive performance and lower variability across cognitive measures. Older adults' daily LPA was positively associated with subjective cognition in both mean levels and variability. The increases in within-person levels of ST were negatively associated with older adults' variability of all cognitive outcomes.</p><p><strong>Discussion and implications: </strong>Study results suggest that moving more and sitting less in day-to-day life may sustain proximal cognitive health. Applying ambulatory assessments can advance aging research by examining the temporal dynamics between daily movement activities and within-person variability of cognition to inform strategies for promoting healthy aging in daily life.</p>","PeriodicalId":13596,"journal":{"name":"Innovation in Aging","volume":"9 6","pages":"igaf059"},"PeriodicalIF":4.3,"publicationDate":"2025-06-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12314498/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144775284","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}