Indonesian Journal of Pharmaceutical and Clinical Research最新文献_第5页

The Effect of Drying Method on The Antioxidant Activity of The Flesh of Nutmeg 干燥方法对肉豆蔻果肉抗氧化活性的影响

Indonesian Journal of Pharmaceutical and Clinical Research Pub Date : 2021-03-18 DOI: 10.31869/IJPR.V1I1.2437

Fita Selonni

引用次数: 1

Optimization of Coating Formula of White Pomegranate Peel Extract (Punica granatum L.) Film Coated Tablet Using Kollicoat Protect 白石榴皮提取物包衣配方的优化薄膜包衣片剂使用kolliccoat保护

Indonesian Journal of Pharmaceutical and Clinical Research Pub Date : 2021-03-18 DOI: 10.31869/IJPR.V1I1.1993

Stefani Luke, M. Ervina, Lannie Hadisoewignyo

{"title":"Optimization of Coating Formula of White Pomegranate Peel Extract (Punica granatum L.) Film Coated Tablet Using Kollicoat Protect","authors":"Stefani Luke, M. Ervina, Lannie Hadisoewignyo","doi":"10.31869/IJPR.V1I1.1993","DOIUrl":"https://doi.org/10.31869/IJPR.V1I1.1993","url":null,"abstract":"White pomegranate peel has many kinds uses, one of them as antimalaria. The unpleasant appearance and bitter taste of white pomegranate peel tablet can be covered by film coated using Kollicoat Protect. This research aimed to determine the effect of concentration and type of solvent used as a coating on the physical properties of the coated tablets and determine the optimum formula. Tablets were made using direct compression method and then coated using Kollicoat Protect. The optimization of coating formula was performed using a factorial design with design expert software ver 10.0. Responses used were tablet hardness, friability, disintegration time and increasing tablet mass. The results of this study showed that Kollicoat Protect cause increase of weight gain tablets and decrease the tablet friability, but prolong the disintegration time of tablets and decrease the tablet hardness while type of solvent can increase of weight gain tablets, tablet hardness, and decrease the tablet friability but prolong the disintegration time of tablets. The optimum combination formula was Kollicoat Protect at 13.6% and combination of water:alcohol (1:0.863) (w/v) with a theoretical response to weight gain of 2.340%; hardness 7.950 kp; friability 0.022%; and disintegration time 20.938 minutes.","PeriodicalId":13466,"journal":{"name":"Indonesian Journal of Pharmaceutical and Clinical Research","volume":"96 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2021-03-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"80403330","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 1

Description of Drug Storage in Melawai Kemang Pharmacy in 2018 2018年马拉威科芒药房药品库存情况分析

Indonesian Journal of Pharmaceutical and Clinical Research Pub Date : 2021-03-18 DOI: 10.31869/IJPR.V1I1.2436

Nurwulan Adi Ismaya, Nining Prihatin, Okpri Melia, N. Hasanah

{"title":"Description of Drug Storage in Melawai Kemang Pharmacy in 2018","authors":"Nurwulan Adi Ismaya, Nining Prihatin, Okpri Melia, N. Hasanah","doi":"10.31869/IJPR.V1I1.2436","DOIUrl":"https://doi.org/10.31869/IJPR.V1I1.2436","url":null,"abstract":"Drug management is the most important management in pharmaceutical services at the pharmacy. Drug storage is an inseparable part of all pharmaceutical activities. Pharmacies including pharmacy service facilities, therefore they must be responsible for drug inventory, maintaining drug supplies to avoid damage and maintaining drug quality. Medicines distributed at pharmacies are the same as drugs distributed in hospitals, therefore a good drug storage system at the pharmacy is the same as storing good medicine in hospitals. This type of research is descriptive research with the main purpose of making an objective picture. Data collection is retrospective by observing and reviewing documents following the drug storage indicators by Pudjaningsih. The population of the study were all medicines. Samples were taken based on the total sampling technique. The research instrument is a stock card and the document resulting from stock opname. The conclusion of this research is an overview of drug storage at Melawai Kemang Pharmacy with indicators suitability of stock card is 97,16 %, percentage of drugs expired and or damaged.","PeriodicalId":13466,"journal":{"name":"Indonesian Journal of Pharmaceutical and Clinical Research","volume":"59 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2021-03-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"82912715","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

The Stability Comparison of Whitening Containing Kojic Acid and Glycolid Acid with The Same Cream Base 同一乳膏碱下含曲酸和乙醇酸的美白稳定性比较

Indonesian Journal of Pharmaceutical and Clinical Research Pub Date : 2021-03-18 DOI: 10.31869/IJPR.V1I1.2429

Siska Ferilda

引用次数: 0

Evaluation of Waiting Time for Outpatient Prescription Services at the Pharmacy Installation at the Universitas Sumatera Utara Hospital 苏门答腊北方大学医院药房门诊处方服务等候时间的评估

Indonesian Journal of Pharmaceutical and Clinical Research Pub Date : 2021-02-08 DOI: 10.32734/idjpcr.v3i2.4430

M. Yunus, Wiryanto, Yuandani

{"title":"Evaluation of Waiting Time for Outpatient Prescription Services at the Pharmacy Installation at the Universitas Sumatera Utara Hospital","authors":"M. Yunus, Wiryanto, Yuandani","doi":"10.32734/idjpcr.v3i2.4430","DOIUrl":"https://doi.org/10.32734/idjpcr.v3i2.4430","url":null,"abstract":"The pharmacy installation is one of the units in the hospital that provides. service products and services in the form of prescription services. Prescription service asthe front line of pharmacy services to patients must be managed properly becausethe quality of pharmaceutical prescription service which is generally associated with the speed ingiving service. This research is a descriptive type of research with prospective data collection from March-June 2019 to evaluate the waiting time for outpatient prescription services at the Hospital Pharmacy Installation of the Universitas Sumatera Utara. The data taken were 357 outpatient prescriptions.The results of this study indicate the total average length of time waiting for outpatients for the provision of non-fake drugs at the Pharmacy Installation of Outpatients at the University of Sumatera Utara Hospital at 09.00 - 11.00 is 29.10 minutes, at 11.00 - 13.00 is 34.44. minutes and at 13.00 - finished 42.60 minutes. The average length of waiting time for outpatients for the provision of compound drugs at the Outpatient Pharmacy Installation of the University of Sumatera Utara Hospital at 09.00 - 11.00 is 51.67 minutes, 11.00 - 13.00 hours is 62.27 minutes and at 13.00 - completion was 65.71 minutes. The waiting time for prescription services is ≤ 60 minutes.Based on the results of research conducted at the Outpatient Pharmacy Installation at the University of Sumatera Utara Hospital, non-concocted prescription drugs meet the requirements if the service time speed is ≤ 30 minutes and the concocted drug prescription fulfills the requirements if the service time speed is ≤ 60 minutes.","PeriodicalId":13466,"journal":{"name":"Indonesian Journal of Pharmaceutical and Clinical Research","volume":"11 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2021-02-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"86057030","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 2

Teratogenic Effects of Arabica Coffee (Coffea arabica L) on Rats During the Organogenesis Period 阿拉比卡咖啡(Coffea Arabica L)对器官发生期大鼠的致畸作用

Indonesian Journal of Pharmaceutical and Clinical Research Pub Date : 2021-01-01 DOI: 10.32734/IDJPCR.V3I2.4311

Reza Destri Anggi, Yuandani, A. Dalimunthe

引用次数: 0

Effect Of Bangun-Bangun Leaves Ethanol Extract On Lipid Profile Ovariectomized Female Rats 班岗班岗叶乙醇提取物对去卵巢雌性大鼠脂质谱的影响

Indonesian Journal of Pharmaceutical and Clinical Research Pub Date : 2021-01-01 DOI: 10.32734/idjpcr.v4i1.5360

Suharyanisa, P. Hasibuan, P. Nasution

{"title":"Effect Of Bangun-Bangun Leaves Ethanol Extract On Lipid Profile Ovariectomized Female Rats","authors":"Suharyanisa, P. Hasibuan, P. Nasution","doi":"10.32734/idjpcr.v4i1.5360","DOIUrl":"https://doi.org/10.32734/idjpcr.v4i1.5360","url":null,"abstract":"Menopause was a condition of the body when ovaries stopped producing ovum; ovum is the main producer of estrogen hormone. Menopause can increasing lipid profile in blood; it causes any problems in the cardiovascular system. People of North Sumatra have long used Bangun-Bangun leaves as a breastfeeding agent; it contains flavonoid bioactive compounds, which are be expected to replace lost estrogen hormone. This study determined the estrogenic activity of Bangun-Bangun leaves ethanol extract (BBLEE) on lipid levels of ovariectomized female rats as a menopausal model. BBLEE has obtained by maceration techniques with 96% ethanol and extract used on 24 ovariectomized rats which were divided into 6 groups. Group 1 (normal), group 2 (positive) was treated by estradiol at dose of 0.18 mg/kg BW, group 3 (negative) was treated by 0.5% Na-CMC and group 4, 5, 6 were treated by BBLEE at dose of 30, 60, 90 mg/kg BW given orally for 14 days. The data were analyzed by ANOVA and Post Hoc Tukey HSD test. The result showed that effective dose of BBLEE was 90 mg/kg BW which improved lipid profile (TC = 55.75±0.47; TG = 63.00±0.40; HDL = 37.00±0.81; LDL = 30.50±0.86) in blood of ovariectomized female rats as a menopausal model. BBLEE at the dose of 90 mg/kg BW can ameliorate the lipid profile in the blood of ovariectomized female rats as a menopausal model.","PeriodicalId":13466,"journal":{"name":"Indonesian Journal of Pharmaceutical and Clinical Research","volume":"1 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2021-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"76778685","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Effect of Adherence with Clinical Outcomes and Quality of Life Primary Hypertension Patients in Pharmacy 药房依从性对原发性高血压患者临床结局和生活质量的影响

Indonesian Journal of Pharmaceutical and Clinical Research Pub Date : 2020-12-31 DOI: 10.32734/idjpcr.v3i2.5129

Dumartina Hutauruk, Khairunnisa, Wiryanto

引用次数: 2

Immunomodulator Activity of Puguntano (Picria fel-terrae Lour.) Extract in White Male Mice By Carbon Clearance Method 蒲公藤的免疫调节活性碳清除法提取白雄性小鼠

Indonesian Journal of Pharmaceutical and Clinical Research Pub Date : 2020-12-31 DOI: 10.32734/IDJPCR.V3I2.4306

Rezza Fikrih Utama, Rosidah, Yuandani

{"title":"Immunomodulator Activity of Puguntano (Picria fel-terrae Lour.) Extract in White Male Mice By Carbon Clearance Method","authors":"Rezza Fikrih Utama, Rosidah, Yuandani","doi":"10.32734/IDJPCR.V3I2.4306","DOIUrl":"https://doi.org/10.32734/IDJPCR.V3I2.4306","url":null,"abstract":"Poguntano Herb Plants (Picria fel-terrae Lour.) contains flavonoids compounds that have been potentially to developed into immunomodulators. The purpose of this study was to determine the immunomodulatory activity of Poguntano herb extract (Picria fel-terrae Lour.), with the method of carbon clearance. n-hexane extract puguntano herb(ENHHP), extract of ethyl acetate of Poguntano herb (EEAHP), and ethanol extract of puguntano herb(EEHP) Poguntano multistage results in the test of immunomodulatory activity with a method of carbon clearance. Results showed that the EEHP 200 mg/kg BB showed a strong immunostimulation effect, EEAHP 200 mg/kg BB showed strong immunostimulation effect, ENHP 200 mg/kg BB demonstrated strong immunostimulation effect. It is thought that extract N-hexane herb Poguntano (ENHHP), extracts of ethyl herb acetate Poguntano (EEAHP), and herb ethanol extract Poguntano (EEHP) Poguntano herb may increase phagocytosis activity. Extract of ethyl acetate Poguntano herb 200 mg/kg bw (EEAHP) has the best phagocytosis activity with a value of 2.376 which indicates there is a significant difference (P < 0.05) with another treatment group.","PeriodicalId":13466,"journal":{"name":"Indonesian Journal of Pharmaceutical and Clinical Research","volume":"42 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2020-12-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"74164864","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 1

Evaluation of Drug Management of Pharmacy Installation at Universitas Sumatera Utara Hospital 苏门答腊北方大学医院药房设备药品管理评价

Indonesian Journal of Pharmaceutical and Clinical Research Pub Date : 2020-12-31 DOI: 10.32734/idjpcr.v3i2.4556

Syilvi Rinda Sari, Khairunnisa, A. Dalimunthe

引用次数: 0