Indonesian Journal of Pharmaceutical and Clinical Research最新文献

Comparison of antihypertensive drug utilization in community health centre and type B teaching hospital 社区卫生中心与B型教学医院降压药使用情况比较

Indonesian Journal of Pharmaceutical and Clinical Research Pub Date : 2023-07-07 DOI: 10.32734/idjpcr.v6i1.11982

Tromphin Sitorus, Abraham Simatupang

{"title":"Comparison of antihypertensive drug utilization in community health centre and type B teaching hospital","authors":"Tromphin Sitorus, Abraham Simatupang","doi":"10.32734/idjpcr.v6i1.11982","DOIUrl":"https://doi.org/10.32734/idjpcr.v6i1.11982","url":null,"abstract":"Antihypertensive medicine is one of the many complex factors contributing to the sustained rise in hypertension prevalence, which remains a global health concern. The Social Security Agency on Health, or Badan Penyelenggara Jaminan Social (BPJS) Kesehatan, in Indonesia is an integrated healthcare system that provides universal healthcare to its citizens. This retrospective cross-sectional study examined the use of antihypertensive medications covered by BPJS between January and December 2021 at the Rawabuntu Primary Health Centre and the Universitas Kristen Indonesia (UKI) type B public hospital. The necessary data was extracted from the medical files of 192 hypertensive patients. The patients' characteristics were analysed descriptively. The rationality of antihypertensive medication use was evaluated in accordance with Association of Indonesian Hypertension Physicians-approved guidelines. The majority of patients in both categories were female (52.1 percent at the Rawabuntu Primary Health Centre and 60 percent at the teaching facility). In both healthcare facilities, the correct indication, patient, and dosage were administered 100 percent of the time, according to this study. While only 66.7% and 85.4% of patients at the Rawabuntu Primary Health Centre and UKI hospital received the correct drug category, respectively. The rational use of antihypertensive medications was substantially lower at the Primary Health Centre than it was at the UKI Hospital (p = 0.001).","PeriodicalId":13466,"journal":{"name":"Indonesian Journal of Pharmaceutical and Clinical Research","volume":"50 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-07-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"90677978","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Herbal Medicines and Recent Development on Novel Herbal Drug Delivery System 中草药及新型中草药给药系统的研究进展

Indonesian Journal of Pharmaceutical and Clinical Research Pub Date : 2023-07-04 DOI: 10.32734/idjpcr.v6i1.11702

A. Ahmed, M. Shuaib, M. Shirsat, Deeksha Sharma

{"title":"Herbal Medicines and Recent Development on Novel Herbal Drug Delivery System","authors":"A. Ahmed, M. Shuaib, M. Shirsat, Deeksha Sharma","doi":"10.32734/idjpcr.v6i1.11702","DOIUrl":"https://doi.org/10.32734/idjpcr.v6i1.11702","url":null,"abstract":"The World Health Organization (WHO) defines herbal medicine as a technique that uses herbs, herbal ingredients, herbal preparations, and finished herbal products. Herbal remedies contain a variety of chemical components known as phytochemicals, which fall into a number of categories including saponins, flavonoids, glycosides, tannins, alkaloids, and terpenoids. Due to the presence of these phytochemicals, herbal medications can be used to treat a variety of ailments and diseases, including gastrointestinal problems, skin infections, arthritis, migraines, and weariness. Herbal medicines have less major adverse effects than conventional pharmaceuticals and are less expensive. \u0000New herbal formulations can include transfersomes, ethosomes, microspheres, phytosomes, liposomes, polymeric nanoparticles, and nanocapsules. In comparison to traditional herbal medicines, the novel herbal drug delivery systems offer many advantages, including increased solubility and bioavailability, protection from side effects, enhanced pharmacological action, increased stability, better delivery to tissue macrophages, consistent delivery, and protection against the physical and chemical breakdown of active ingredients. To incorporate standardised herbal extract or aqueously soluble active ingredients into phospholipids to build lipid companionable molecular complexes, phytosome has been described as a patented innovative herbal technology produced by a leading manufacturer of medicines and nutraceuticals. The use of herbal medicines can be expanded in order to increase their efficacy by incorporating them into more sophisticated medications.","PeriodicalId":13466,"journal":{"name":"Indonesian Journal of Pharmaceutical and Clinical Research","volume":"314 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-07-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"77572213","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Prevalence, management and complications of diabetic patients in pabna city 巴布纳市糖尿病患者的患病率、治疗及并发症

Indonesian Journal of Pharmaceutical and Clinical Research Pub Date : 2023-06-28 DOI: 10.32734/idjpcr.v6i1.10411

G M Masud Parvez, None Rumayesha, Mst. Shanzida Parvin, Aziza Afrin, Abul Kalam Azad, Mst. Mahabuba Aktar, Md. Fazle Rabbi, Sumaiya Rashid, Akila Farjana, Most. Anika Naznin, Razia Sultana, Shumaia Parvin, Md. Abdul Kader

{"title":"Prevalence, management and complications of diabetic patients in pabna city","authors":"G M Masud Parvez, None Rumayesha, Mst. Shanzida Parvin, Aziza Afrin, Abul Kalam Azad, Mst. Mahabuba Aktar, Md. Fazle Rabbi, Sumaiya Rashid, Akila Farjana, Most. Anika Naznin, Razia Sultana, Shumaia Parvin, Md. Abdul Kader","doi":"10.32734/idjpcr.v6i1.10411","DOIUrl":"https://doi.org/10.32734/idjpcr.v6i1.10411","url":null,"abstract":"Diabetes is one of the leading causes of death and its prevalence is increasing day by day. This survey was conducted by direct interviewing to the diabetic patients. In this study, the interviewees were the diabetic affected patients of Pabna district. About 1100 persons were interviewed among them 37.55% were male and 62.45% were female. Most of the patients have onset of diabetes at 41-50 years age. Most of our observed patients have suffered from diabetes between 1-5 years (62.64%) followed by 6-10 years (25.18%). Here 3.18% patients have BMI ≤18.5, 47.55% have between 18.5-24.9, 39.55% have BMI 25.5-29.9 and 9.73% have BMI ≥30. Here 93.45% diabetic patients have blood glucose level of >7 mmol/L. The diabetic patients also suffered from retinopathy 50.36%, neuropathy 19.73%, nephropathy 23.55% and foot problem 43.36%. About 63.27% are taking diet, 56.91% are taking exercise and 93.91% are taking drug for treating diabetes. It was found that the patients are suffering from different other diseases. The patients need to be aware about the potential risk of other diseases.","PeriodicalId":13466,"journal":{"name":"Indonesian Journal of Pharmaceutical and Clinical Research","volume":"3 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-06-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"135309904","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Proximate Composition of Anadara granosa and Paphia undulata 大水仙和波形帕菲亚的近似组成

Indonesian Journal of Pharmaceutical and Clinical Research Pub Date : 2023-06-23 DOI: 10.32734/idjpcr.v6i1.9196

Y. Permata, Anggi Tri Liesna, Fahmi Muhammad Rangkuti, Kharisma Insyra, Yasmin Dayanti

引用次数: 0

Carbohydrate Content in Packaged Chicken Nuggets: Qualitative And Quantitative Analysis 包装鸡块中的碳水化合物含量:定性和定量分析

Indonesian Journal of Pharmaceutical and Clinical Research Pub Date : 2023-02-16 DOI: 10.31869/ijpr.v2i2.4174

Syifa Alifia Indriani, Nurul Asfia, Agnes Manongga, Riong seulina Panjaitan

{"title":"Carbohydrate Content in Packaged Chicken Nuggets: Qualitative And Quantitative Analysis","authors":"Syifa Alifia Indriani, Nurul Asfia, Agnes Manongga, Riong seulina Panjaitan","doi":"10.31869/ijpr.v2i2.4174","DOIUrl":"https://doi.org/10.31869/ijpr.v2i2.4174","url":null,"abstract":"Nugget products can be made from beef, chicken, fish, and other ingredients, but chicken nuggets are the most popular in the community. Chicken nuggets are products produced from the marinated, ground, minced, and cooked parts of chicken breast meat with breadcrumbs. Qualitative and quantitative tests of carbohydrates are carried out to determine the presence of carbohydrates present in nuggets. Qualitative tests are based on changes in color or deposits formed, while quantitative tests to determine the carbohydrate levels contained in each test material with DNS method. The results showed qualitative analysis of molisch test carbohydrates on samples of chicken meat nuggets brand \"B,\" which positively contained carbohydrates (glucose), while samples of chicken meat nuggets brands \"A\" and \"C\" showed negative results. In the Iodin test, all three nugget samples showed positive results for glycogen. The Benedict test yielded negative results for all three nugget samples, indicating that none of them contained sucrose. The three nugget samples all failed the Barfoed test, indicating that they are all members of the disaccharide group. The Seliwanoff test yielded negative results for all three nugget samples, all of which contained glucose, mannose, or galactose. The Osazon test yielded negative results for all three nugget samples. Carbohydrate quantitative test obtained sample concentration on sample nugget of chicken meat brand \"A\" 0.49 mg/mL, sample of chicken meat nugget brand \"B\" 0.48 mg/mL and sample nugget of chicken meat brand \"C\" 0.56 mg/mL. Carbohydrate qualitative analysis on samples of chicken meat nuggets from brand \"B\" reveals that they positively contain carbohydrates as well as fructose and glycogen. The \"C\" brand chicken meat nugget sample has a high concentration for quantitative analysis of carbohydrates, indicating that the sample contains more carbohydrates.","PeriodicalId":13466,"journal":{"name":"Indonesian Journal of Pharmaceutical and Clinical Research","volume":"224 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-02-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"76000508","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Description of Knowledge and Attitudes of Young Women in Rowosari Village, Pemalang Regency Against the Dangers of Retinoic Acid in Face Whitening Cream 白马郎县Rowosari村年轻妇女对面部美白霜中维甲酸危害的知识和态度描述

Indonesian Journal of Pharmaceutical and Clinical Research Pub Date : 2023-02-16 DOI: 10.31869/ijpr.v2i2.4177

Tyas Putri Utami, Nila Oktaviani

{"title":"Description of Knowledge and Attitudes of Young Women in Rowosari Village, Pemalang Regency Against the Dangers of Retinoic Acid in Face Whitening Cream","authors":"Tyas Putri Utami, Nila Oktaviani","doi":"10.31869/ijpr.v2i2.4177","DOIUrl":"https://doi.org/10.31869/ijpr.v2i2.4177","url":null,"abstract":"Kulit halus dan putih adalah salah satu keindahan Kulit halus dan putih adalah salah satu konsep kecantikan orang Indonesia saat ini, dan sebagian besar orang Indonesia memiliki kulit sawo matang. Filosofi kecantikan ini membuat masyarakat Indonesia khususnya remaja putri, berusaha keras untuk mendapatkan kulit yang cerah, dan salah satunya adalah dengan menggunakan kosmetik yang mengandung krim pemutih dan pencerah. Remaja mulai tertekan terhadap penampilan yang menginginkan kulit putih dengan menggunakan krim pemutih tanpa memperhatikan ada atau tidaknya komposisi dan izin edar atau terdaftar di BPOM. Tujuan penelitian ini adalah untuk mengetahui gambaran pengetahuan dan sikap remaja putri di Desa Rowosari Kabupaten Pemalang terhadap bahaya asam retinoat pada krim pemutih wajah. Jenis penelitian ini adalah survey deskriptif dan penelitian ini dilaksanakan di Desa Rawosari Kecamatan Ulujami Kabupaten Pemarang. Sampel penelitian ini adalah 100 remaja putri berusia antara 15-19 tahun yang diperoleh dengan cara simple random sampling. Hasil penelitian menunjukkan bahwa 56 orang (56,0%) memiliki pemahaman yang baik tentang pengetahuan bahaya asam retinoat dalam krim pemutih, dan 95 orang (95,0%) memiliki sikap tertinggi dengan kategori baik.","PeriodicalId":13466,"journal":{"name":"Indonesian Journal of Pharmaceutical and Clinical Research","volume":"34 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-02-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"89388771","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Repellent Activity Test Of Essential Oil Gel Of Cinnamommum Burmanii Bi Leaves Against Aedes Aegypti Mosquitoes 肉桂叶精油凝胶对埃及伊蚊的驱避活性试验

Indonesian Journal of Pharmaceutical and Clinical Research Pub Date : 2023-02-16 DOI: 10.31869/ijpr.v2i2.4180

Bayuadi Bayuadi, Purwati Purwati, Riong seulina Panjaitan

引用次数: 0

COMPARISON OF ACID NUMBERS IN BULK AND PACKAGED COOKING OIL SAMPLES 散装和包装食用油样品中酸值的比较

Indonesian Journal of Pharmaceutical and Clinical Research Pub Date : 2023-02-15 DOI: 10.31869/ijpr.v2i2.4155

Liany Carolina Rambu Lika, Sahda Sabilah Luhtansa, Septiana Berbara Blaon, Riong seulina Panjaitan

引用次数: 0

QUALITATIVE AND QUANTITATIVE IDENTIFICATION OF CARBOHYDRATES IN COMMERCIAL YOGHURT PRODUCTS 商品酸奶产品中碳水化合物的定性和定量鉴定

Indonesian Journal of Pharmaceutical and Clinical Research Pub Date : 2023-02-06 DOI: 10.31869/ijpr.v2i2.4134

Bagus Nurprialdi, Viesta Olivia Thahuurun Gani, Siti Halda, Peby Ardiani Pratama, Riong seulina Panjaitan

{"title":"QUALITATIVE AND QUANTITATIVE IDENTIFICATION OF CARBOHYDRATES IN COMMERCIAL YOGHURT PRODUCTS","authors":"Bagus Nurprialdi, Viesta Olivia Thahuurun Gani, Siti Halda, Peby Ardiani Pratama, Riong seulina Panjaitan","doi":"10.31869/ijpr.v2i2.4134","DOIUrl":"https://doi.org/10.31869/ijpr.v2i2.4134","url":null,"abstract":"Yogurt is a healthy drink that has thick, acidic properties and a high nutritional content. Yogurt is made by adding bacteria to milk, which naturally contains a type of sugar (carbohydrate) called lactose.Qualitative testing methods for carbohydrates are the Molisch test, the iodine test, the Benedict test, the Barfoed test, the Seliwanoff test, and the osazon test. Meanwhile, in quantitative testing using the DNS method. The results of the Molisch carbohydrate qualitative test revealed that all four samples contained glucose. Polysaccharides were discovered in the six samples during the iodine test. The six samples tested negative for glucose in Benedict's test. One out of every six samples tested positive for monosaccharides in the Barfoed test. Both samples tested positive for fructose in the Seliwanoff test. In the osazone test, all yogurt samples contained glucose. Furthermore, the following results were obtained when determining the reducing sugar content of commercial yogurt samples: E (685 mg/mL); D (568.75 mg/mL); F (501.25 mg/mL); A (373.75 mg/mL); B (310 mg/mL); and C (210 mg/mL).","PeriodicalId":13466,"journal":{"name":"Indonesian Journal of Pharmaceutical and Clinical Research","volume":"1 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-02-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"89998524","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 1

STUDY OF POTENTIAL DRUG INTERACTIONS IN PULMONARY TB PATIENTS IN dr. GONDO SUWARNO HOSPITAL SEMARANG DISTRICT 2021 2021年三宝垄区GONDO SUWARNO医生医院肺结核患者潜在药物相互作用的研究

Indonesian Journal of Pharmaceutical and Clinical Research Pub Date : 2023-01-19 DOI: 10.31869/ijpr.v2i2.3941

Iswandi Iswandi

{"title":"STUDY OF POTENTIAL DRUG INTERACTIONS IN PULMONARY TB PATIENTS IN dr. GONDO SUWARNO HOSPITAL SEMARANG DISTRICT 2021","authors":"Iswandi Iswandi","doi":"10.31869/ijpr.v2i2.3941","DOIUrl":"https://doi.org/10.31869/ijpr.v2i2.3941","url":null,"abstract":"Tuberkulosis (TB) adalah salah satu penyakit menular dengan tingkat kematian tertinggi di dunia yang disebabkan oleh Bakteri Mycobacterium tuberculosis. Pasien tuberkulosis dengan penyakit penyerta diobati dengan obat tambahan untuk mengobati penyakit penyerta, hal ini menyebabkan peningkatkan potensi interaksi obat. Tujuan penelitian adalah untuk mengetahui obat yang berpotensi menyebabkan interaksi obat terhadap pasien TB paru di RSUD dr. Gondo Suwarno Tahun 2021. Jenis penelitian ini deskriptif non eksperimental dengan pengumpulan data retrospektif. Sampel dalam penelitian ini adalah pasien TB Paru yang tertera di rekam medis dan mendapat pengobatan antituberkulosis (OAT) dan non-OAT di RSUD dr. Gondo Suwarno tahun 2021 dan disesuaikan dengan kriteria inklusi. Potensi interaksi obat antar OAT meliputi interaksi farmakokinetik (34%), farmakodinamik (66%) dan unknown tidak teridentifikasi. Berdasarkan tingkat keparahan, major (194 kasus), moderate (96 kasus), dan minor tidak teridentifikasi. Pada potensi interaksi obat OAT dengan non-OAT meliputi interaksi farmakokinetik (94%), farmakodinamik (4%) dan unknown (2%). Berdasarkan tingkat keparahan, major (23 kasus), moderate (214 kasus), dan minor (42 kasus).","PeriodicalId":13466,"journal":{"name":"Indonesian Journal of Pharmaceutical and Clinical Research","volume":"26 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-01-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"74797946","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0