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SIMULTANEOUS UV METHOD DEVELOPMENT FOR DETERMINATION OF ROTIGOTINE HYDROCHLORIDE AND RASAGILINE MESYLATE 紫外分光光度法测定盐酸罗替戈汀和甲磺酸雷沙吉兰的含量
INDIAN DRUGS Pub Date : 2023-05-28 DOI: 10.53879/id.60.05.13373
Shivani M. Patel, Lalit L. Jha
{"title":"SIMULTANEOUS UV METHOD DEVELOPMENT FOR DETERMINATION OF ROTIGOTINE HYDROCHLORIDE AND RASAGILINE MESYLATE","authors":"Shivani M. Patel, Lalit L. Jha","doi":"10.53879/id.60.05.13373","DOIUrl":"https://doi.org/10.53879/id.60.05.13373","url":null,"abstract":"A precise, accurate analytical UV spectroscopic method has been developed for simultaneous estimation of rotigotine hydrochloride and rasagiline mesylate by using first order derivative spectroscopy. 50 µg mL-1 solutions of both drugs were scanned in the range of 200-800 nm and the first order overlain spectra of both drugs to check zero crossing points. Rotigotine hydrochloride showed zero crossing point at 239 nm where and rasagiline mesylate showed at 273 nm. Six-point calibration curves shown linearity in 2-12 µg mL-1 concentration range for rotigotine hydrochloride and 10-60 µg mL-1 concentration range for rasagiline mesylate. Regression equation obtained for both drugs were used further for determination of concentration in accuracy studies and developed product. In bulk drugs, rasagiline mesylate showed recovery of 98.33-100.93 % and rotigotine hydrochloride showed recovery of 101-103 %. The results obtained from analysis were validated according to ICH guidelines and were found at up to the mark.","PeriodicalId":13409,"journal":{"name":"INDIAN DRUGS","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-05-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"48435634","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
PHYTOCHEMICAL ANALYSIS, ANTIOXIDANT ACTIVITY AND FTIR SPECTROSCOPIC ANALYSIS OF RED LEAF LETTUCE AND GREEN LEAF LETTUCE (LACTUCA SATIVA L.) 红叶莴苣和绿叶莴苣的植物化学分析、抗氧化活性及红外光谱分析
INDIAN DRUGS Pub Date : 2023-05-28 DOI: 10.53879/id.60.05.13378
N. Utami, Prashinta N. Damayanti
{"title":"PHYTOCHEMICAL ANALYSIS, ANTIOXIDANT ACTIVITY AND FTIR SPECTROSCOPIC ANALYSIS OF RED LEAF LETTUCE AND GREEN LEAF LETTUCE (LACTUCA SATIVA L.)","authors":"N. Utami, Prashinta N. Damayanti","doi":"10.53879/id.60.05.13378","DOIUrl":"https://doi.org/10.53879/id.60.05.13378","url":null,"abstract":"This study was conducted to analyze the phytochemical compounds, the profile of infrared spectrophotometric, total phenolic contents (TPC) and antioxidant activity of ethanol extract of red leaf lettuce (RL) and green leaf lettuce (GL). RL and GL were extracted with 70 % ethanol using the maceration method for 3 days and re-maceration for 1 day. The secondary metabolites in ethanol extracts were evaluated by phytochemical analysis and profile spectra infrared. Estimation of TPC was conducted by the FolinCiocalteu methods. The antioxidant activity assay was conducted by ABTS and DPPH methods. The determination of TPC showed that the ethanol extract of RL was higher than the ethanol extract of GL. RL has stronger antioxidant activity than GL. The presence of hydroxyl group in the phenolics directly correlates with the antioxidant activity, so consumers could use them as natural antioxidants or to functionalize foods. This understanding is important for improving the safety and quality of leaf lettuce.","PeriodicalId":13409,"journal":{"name":"INDIAN DRUGS","volume":"1 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-05-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"71131648","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
METHOD DEVELOPMENT AND VALIDATION OF FLURBIPROFEN SODIUM BY USING UPLC 方法建立氟比洛芬钠的高效液相色谱法
INDIAN DRUGS Pub Date : 2023-05-28 DOI: 10.53879/id.60.05.12864
Shraddha V. Tathe, Shivangi Gupta
{"title":"METHOD DEVELOPMENT AND VALIDATION OF FLURBIPROFEN SODIUM BY USING UPLC","authors":"Shraddha V. Tathe, Shivangi Gupta","doi":"10.53879/id.60.05.12864","DOIUrl":"https://doi.org/10.53879/id.60.05.12864","url":null,"abstract":"A simple, precise, and accurate ultra-performance liquid chromatography was developed for flurbiprofen sodium on Acquity BEHC18, (50 x 2.1 mm, 1.7 µm) using acetonitrile: water: glacial acetic acid as the mobile phase. The flow rate was 0.2 mL min-1 and effluent was monitored at 254 nm. The retention time for flurbiprofen sodium was found to be 2.3. Developed method was validated for precision, accuracy, linearity range, robustness and ruggedness as per ICH guideline","PeriodicalId":13409,"journal":{"name":"INDIAN DRUGS","volume":"1 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-05-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"41543766","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
IN SILICO ANALYSIS OF PHYTOCHEMICALS FROM VARIOUS PLANT SOURCES AS DRUG CANDIDATES AGAINST LIFE-THREATENING DISEASES 来自不同植物来源的植物化学物质作为治疗危及生命的疾病的候选药物的计算机分析
INDIAN DRUGS Pub Date : 2023-05-28 DOI: 10.53879/id.60.05.13290
S. Jamkhedkar, Anakha P. Nair, Kishori R. Hirode, Mayuri D. Chavan, Mili P. Jain, Prachi P. Majumdar
{"title":"IN SILICO ANALYSIS OF PHYTOCHEMICALS FROM VARIOUS PLANT SOURCES AS DRUG CANDIDATES AGAINST LIFE-THREATENING DISEASES","authors":"S. Jamkhedkar, Anakha P. Nair, Kishori R. Hirode, Mayuri D. Chavan, Mili P. Jain, Prachi P. Majumdar","doi":"10.53879/id.60.05.13290","DOIUrl":"https://doi.org/10.53879/id.60.05.13290","url":null,"abstract":"Epigenetic changes and glycation play a significant role in the progression of life-threatening diseases like diabetes, cancer, cardiovascular diseases (CVDs), neurodegenarative diseases (ND) and others. Exploring natural sources for overall therapeutic effect can be a beneficial approach for treating these life threatening diseases. The phytocemicals apigenin, aegeline, marmelosin, kaempferol, pyrrolemarumine 4”-O-alpha-L-rhamnopyranoside and garcinol from Durva, Bael, Custard apple, Moringa and Kokum were evaluated for their therapeutic value using in silico techniques. These phytochemicals and target structures (molecules from diseases pathologies from KEGG database), were obtained from PubChem and PDB, respectively. The docking studies, pharmaceutical parameters and toxicity studies were done using Swiss Dock, Swiss ADME for and Pro Tox II. The above phytochemicals have shown optimal lipophilicity, insaturation, flexibility and solubility. Molecular weight was less than 500 Da and LD50 values for each of these was above 400 mg kg-1. Amongst all phytochemicals, garcinol was found to be ideal for dermal drugs.","PeriodicalId":13409,"journal":{"name":"INDIAN DRUGS","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-05-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"42153907","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
THE GLOBAL NUTRACEUTICAL DOMAIN 全球营养领域
INDIAN DRUGS Pub Date : 2023-05-28 DOI: 10.53879/id.60.05.p0005
{"title":"THE GLOBAL NUTRACEUTICAL DOMAIN","authors":"","doi":"10.53879/id.60.05.p0005","DOIUrl":"https://doi.org/10.53879/id.60.05.p0005","url":null,"abstract":"Dear Reader, Nutraceuticals is no more a fancy word shrouded in a mysterious veil. It is a gospel truth and now a well-embraced norm, that ‘positive health’ can only be fostered by nutraceuticals – be it called supplements, ayurceuticals or herbals. Although advocating and consuming ayurceuticals is an Indian-centric reality, the impetus to embracing nutraceuticals (which is a general term encompassing supplements and biologicals or herbals) by Indians has definitely come from the globally proliferating OTC (Over-The-Counter) market with such products and their overflowing into the Indian subcontinent in the 1990s!","PeriodicalId":13409,"journal":{"name":"INDIAN DRUGS","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-05-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"44044862","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
MULMINATM REVERSES MEMORY IMPAIRMENT INDUCED BY GABAPENTIN IN PTZ EPILEPTIC MOUSE MODEL AND EXHIBITS SYNERGISTIC ANTIEPILEPTIC ACTIVITY MULMINATM在PTZ癫痫小鼠模型中逆转加巴喷丁诱导的记忆障碍并表现出协同抗癫痫活性
INDIAN DRUGS Pub Date : 2023-05-28 DOI: 10.53879/id.60.05.12969
Bhooshitha A. Nagesh, Sneha Desai, Krishna K. Linganna, A. Shreyas, Abhishek P. R. Nadiga, S. Mehdi, S. Pathak, Sunil S. Chiplunkar
{"title":"MULMINATM REVERSES MEMORY IMPAIRMENT INDUCED BY GABAPENTIN IN PTZ EPILEPTIC MOUSE MODEL AND EXHIBITS SYNERGISTIC ANTIEPILEPTIC ACTIVITY","authors":"Bhooshitha A. Nagesh, Sneha Desai, Krishna K. Linganna, A. Shreyas, Abhishek P. R. Nadiga, S. Mehdi, S. Pathak, Sunil S. Chiplunkar","doi":"10.53879/id.60.05.12969","DOIUrl":"https://doi.org/10.53879/id.60.05.12969","url":null,"abstract":"Epilepsy is a neurological condition that causes unprovoked, recurrent seizures and memory impairment is a common side effect of epileptic treatment. The present study was conceptualized to evaluate the protective effect of the nootropic herbal drink MulminaTM against memory impairment induced by Gabapentin in a pentylenetetrazole-induced epileptic mouse model. The antiepileptic and memory impairment activity were found to be significantly (p<0.05) higher in the gabapentin group, whereas the combination of gabapentin + MulminaTM significantly (p<0.05) increased antiepileptic and decreased the memory impairment activity. Furthermore, Mulmina, alone exhibited synergistic antiepileptic and memory enhancement activity. Thus, combining herbal drugs/nootropics with anti-epileptic drugs provides synergistic activity while lowering the dose of synthetic drugs, which may cause more adverse effects in the human body. The results of this study show that gabapentin has memory impairment potential and that it can be corrected by co-administration of MulminaTM. However, future research is warranted to assess the underlying molecular mechanism of memory enhancing activity of MulminaTM against gabapentin induced memory impairment.","PeriodicalId":13409,"journal":{"name":"INDIAN DRUGS","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-05-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"45385160","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
UV SPECTROSCOPIC METHOD DEVELOPMENT AND VALIDATION OF FIRST DERIVATIVE METHOD FOR SIMULTANEOUS ESTIMATION OF PRAZIQUANTEL AND ABAMECTIN IN FINISHED DOSAGE FORM 紫外光谱法同时测定成品剂型中吡喹酮和阿维菌素的一阶导数法的建立与验证
INDIAN DRUGS Pub Date : 2023-05-28 DOI: 10.53879/id.60.05.12653
Brijesh K. Dasvani, Avani P. Khristi
{"title":"UV SPECTROSCOPIC METHOD DEVELOPMENT AND VALIDATION OF FIRST DERIVATIVE METHOD FOR SIMULTANEOUS ESTIMATION OF PRAZIQUANTEL AND ABAMECTIN IN FINISHED DOSAGE FORM","authors":"Brijesh K. Dasvani, Avani P. Khristi","doi":"10.53879/id.60.05.12653","DOIUrl":"https://doi.org/10.53879/id.60.05.12653","url":null,"abstract":"In the present investigation, methanol is employed as the solubilizing agent to solubilize poorly water soluble drugs such as praziquantel and abamectin. UV spectrophotometric method has been developed for simultaneous estimation of praziquantel and abamectin in bulk drug and in their combined pharmaceutical dosage form by first order derivative method. This method utilizes methanol as a common solvent and λmax of praziquantel and abamectin selected for analysis was found to be at 248 nm (at ZCP of abamectin) and 274 nm (at ZCP of praziquantel), respectively. Linearity was observed in the concentration range of 25-150 µg mL-1 for praziquantel (r2 = 0.9984) and 1-11 µg mL-1 for ABAM (r2 = 0.9986). The accuracy and precision were determined and found to comply with ICH guidelines. This method shows good reproducibility and recovery with % RSD in the desired range. Developed method was applied for marketed formulation. The results were found to be within acceptance criteria according to ICH guideline","PeriodicalId":13409,"journal":{"name":"INDIAN DRUGS","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-05-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"48329294","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
SOLID LIPID NANOPARTICLES OF GABAPENTIN FOR PARTIAL SEIZURES 加巴喷丁固体脂质纳米颗粒治疗部分性癫痫发作
INDIAN DRUGS Pub Date : 2023-05-28 DOI: 10.53879/id.60.05.13037
Shital Kamathe, Nagesh C., Suma N, P. Patil, Chaitali Muchandi
{"title":"SOLID LIPID NANOPARTICLES OF GABAPENTIN FOR PARTIAL SEIZURES","authors":"Shital Kamathe, Nagesh C., Suma N, P. Patil, Chaitali Muchandi","doi":"10.53879/id.60.05.13037","DOIUrl":"https://doi.org/10.53879/id.60.05.13037","url":null,"abstract":"The goal of this research was to create a stable formulation of gabapentin solid lipid nanoparticles which would allow it to pass across the blood-brain barrier more easily. They were prepared by solvent evaporation method. In the present investigation, beeswax and carnauba wax were used as solid lipids, egg lecithin was used as a surfactant and Tween 80 was used as a co-surfactant. Nine formulations were formulated using different concentrations of solid lipid and surfactant. The prepared formulations were evaluated for various tests. The results shown that F6 formulation, containing higher concentration of egg lecithin, was a better formulation as percentage drug content was 97.57±0.62%, entrapment efficiency was 95.95±0.07% and in vitro release of gabapentin was 97.18±1.02% at the end of 12 h. After in vivo testing, it was observed that animals treated with gabapentin loaded solid lipid nanoparticles had seizures that appeared later than animals treated with traditional gabapentin formulations. Hence it was concluded that solid lipid nanoparticles is a promising drug delivery system to achieve increased permeability through blood brain barrier.","PeriodicalId":13409,"journal":{"name":"INDIAN DRUGS","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-05-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"44137240","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
SYNTHESIS, CHARACTERIZATION AND ANTIMICROBIAL EVALUATION OF NOVEL BIS-HETERO CYCLIC DERIVATIVES 新型双杂环衍生物的合成、表征及抗菌性能评价
INDIAN DRUGS Pub Date : 2023-05-28 DOI: 10.53879/id.60.05.13553
Sathish K. Konidala, G. Kamala, Srinivasan Nagarajan, Durga R. Gunna
{"title":"SYNTHESIS, CHARACTERIZATION AND ANTIMICROBIAL EVALUATION OF NOVEL BIS-HETERO CYCLIC DERIVATIVES","authors":"Sathish K. Konidala, G. Kamala, Srinivasan Nagarajan, Durga R. Gunna","doi":"10.53879/id.60.05.13553","DOIUrl":"https://doi.org/10.53879/id.60.05.13553","url":null,"abstract":"The present research outlines a series of bis-hetero cyclic derivatives (a1-6) synthesized from methyl-1-(2, 5-dioxopyrrolidin-1-yl) -6- methyl -2- oxo -4- phenyl -1, 2, 3, 4- tetrahydro pyrimidine -5- carboxylate treated with different aromatic aldehydes under acidic environment. The synthesized titled derivatives were confirmed by determination of physicochemical properties, by different spectral data and they were evaluated for in vitro antibacterial activity against Bacillus subtilis, Staphylococcus aureus, Escherichia coli and Pseudomonas aeruginosa and antifungal activity against Aspergillus niger and Candida albicans organisms at 25, 50, 100 µg mL-1 concentrations using streptomycin and fluconazole as reference standard drug respectively, through cup plate method. The in vitro antimicrobial assay results indicated that the derivatives a1, a2 and a3 showed significant antimicrobial activity, whereas the remaining derivatives showed moderate antimicrobial activities compared to the standard drugs. Further extension of this research to the cellular level is required to describe the mechanism of action, efficacy, and structural activity of these derivatives for antimicrobial activity.","PeriodicalId":13409,"journal":{"name":"INDIAN DRUGS","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-05-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"47994361","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
STABILITY INDICATING ISOCRATIC HPLC APPROACH TO QUANTIFY MONTELUKAST AND BILASTINE MIX IN BULK AND TABLET FORMULATION 稳定性表明等密度高效液相色谱法定量散装和片剂孟鲁司特和bilastine混合物
INDIAN DRUGS Pub Date : 2023-05-28 DOI: 10.53879/id.60.05.12856
Balaji Gupta V.L.N. Tiruveedhi, Venkateswara Rao Battula, Kishore Babu Bonige, Ramanjaneyulu V. V. Matlapudi
{"title":"STABILITY INDICATING ISOCRATIC HPLC APPROACH TO QUANTIFY MONTELUKAST AND BILASTINE MIX IN BULK AND TABLET FORMULATION","authors":"Balaji Gupta V.L.N. Tiruveedhi, Venkateswara Rao Battula, Kishore Babu Bonige, Ramanjaneyulu V. V. Matlapudi","doi":"10.53879/id.60.05.12856","DOIUrl":"https://doi.org/10.53879/id.60.05.12856","url":null,"abstract":"This paper describes an novel, rapid, simple, meticulous and unerring “stability indicating HPLC method” for the assessment of montelukast (MTT) and bilastine (BLE) mix in existence of their degradation products in tablet formulation. Zorbax column XDB-C18 was utilized to separate and analyse MTT and BLE mix. The isocratic mode elution of BLE and MTT mix was made with 0.1M disodium hydrogen phosphate buffer of pH 5.8 (55 % volume ratio) and methanol (45% volume ratio) at 1.0 mL min-1 flow stream. Strong linearity was recorded within the 2.5 - 20 µg mL-1 and 5 - 40 µg mL-1 concentration ranges, with coefficient determination values of 0.9994 and 0.9997, respectively, for MTT and BLE. The recovery percentiles of MTT and BLE were 99.593 % and 99.349 %, respectively. The precision displayed values less than 0.520 % for MTT and less than 0.745 % for BLE. The robustness too was shown in the chromatographic settings by minor variations. The specificity besides stability representing feature was evidenced since the degradation products arisen in stress situations did not interlope in the determination of MTT and BLE mix. Thus, this procedure can be applied for quality regulation analysis of BLE and MTT mix in formulations of tablets.","PeriodicalId":13409,"journal":{"name":"INDIAN DRUGS","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-05-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"42569244","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
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