Indian Journal of Dermatology最新文献

{"title":"Therapeutic Efficacy of Modified Technique of Homologous Autoimplantation in Multiple and Recurrent <i>Verruca Vulgaris</i>.","authors":"Sumit Kaur, Sumir Kumar, Balvinder Kaur Brar, Shivangi Rana, Amit Kumar Meena","doi":"10.4103/ijd.ijd_539_24","DOIUrl":"10.4103/ijd.ijd_539_24","url":null,"abstract":"","PeriodicalId":13401,"journal":{"name":"Indian Journal of Dermatology","volume":"71 4","pages":"310-312"},"PeriodicalIF":1.7,"publicationDate":"2026-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13336546/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148436540","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Concurrent Appearance of Inverted Follicular Keratosis with Epidermal Cyst: Is there any Association?","authors":"Shree Dhanani, Shubhangi Hirma, Keyur Patel, Pragya A Nair","doi":"10.4103/ijd.ijd_881_24","DOIUrl":"10.4103/ijd.ijd_881_24","url":null,"abstract":"","PeriodicalId":13401,"journal":{"name":"Indian Journal of Dermatology","volume":"71 4","pages":"320-321"},"PeriodicalIF":1.7,"publicationDate":"2026-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13336644/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148436560","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"\"Constriction Bands, Fused Fingers, Clubfoot, and Absent Digits\" - What is This Rare Condition?","authors":"Febin Ashraf, Vivek K Bharti","doi":"10.4103/ijd.ijd_1071_24","DOIUrl":"10.4103/ijd.ijd_1071_24","url":null,"abstract":"","PeriodicalId":13401,"journal":{"name":"Indian Journal of Dermatology","volume":"71 4","pages":"330-332"},"PeriodicalIF":1.7,"publicationDate":"2026-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13336545/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148436584","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"A Clinical Study on Efficacy of Injection Cyclophosphamide Monthly Pulse in Patients with Autoimmune Bullous Disorders.","authors":"Nirmaladevi Palanivel, Soundharyaa Moorthi, A Josphin Lisha, A N M Maalik Babu, P Kalyanakumar","doi":"10.4103/ijd.ijd_602_23","DOIUrl":"10.4103/ijd.ijd_602_23","url":null,"abstract":"","PeriodicalId":13401,"journal":{"name":"Indian Journal of Dermatology","volume":"71 4","pages":"327-329"},"PeriodicalIF":1.7,"publicationDate":"2026-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13336540/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148436511","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Sclerodermiform Lupus Erythematosus - A Rare Entity.","authors":"N R Vignesh, N Ashok Kumar, C Balakumaran, P Sowmya","doi":"10.4103/ijd.ijd_911_24","DOIUrl":"10.4103/ijd.ijd_911_24","url":null,"abstract":"","PeriodicalId":13401,"journal":{"name":"Indian Journal of Dermatology","volume":"71 4","pages":"318-319"},"PeriodicalIF":1.7,"publicationDate":"2026-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13336647/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148436600","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"A Comparative Study: Can Large Language Models be a Supportive Tool in the Diagnosis and Treatment of Scabies?","authors":"İstem Ş Çamur, Eren Çamur, Duru T Onan","doi":"10.4103/ijd.ijd_18_25","DOIUrl":"10.4103/ijd.ijd_18_25","url":null,"abstract":"<p><strong>Background: </strong>The advent of large language models (LLMs) has endowed artificial intelligence with remarkable capabilities to comprehend and generate human-like text by leveraging extensive datasets. Numerous studies in medicine increasingly focus on LLMs, particularly highlighting their substantial potential in diagnostic and therapeutic management. Scabies is a contagious skin disease that continues to affect over 200 million people globally each year and is particularly prevalent in developing countries. In recent years, there has been a marked increase in scabies cases both in Turkey and worldwide, elevating scabies to the status of a public health concern. Therefore, the Clinical Practice Guideline for the Diagnosis and Treatment of Scabies (CPGDT) was published in 2024.</p><p><strong>Aims and objectives: </strong>This study evaluates the performance of LLMs on scabies-related questions created from CPGDT and compares it to a dermatologist.</p><p><strong>Materials and methods: </strong>Sixty-four multiple-choice questions in English were administered to nine LLMs, including Claude 3 Opus, ChatGPT (versions 3.5, 4, and 4o), Google Gemini (1.0 and 1.5 Pro), Microsoft Copilot, Meta LLaMA 3 70B, and Perplexity, as well as to a senior dermatologist with 22 years of experience in dermatology. Responses were scored as correct or incorrect. Statistical analyses, including the McNemar test, were conducted using IBM SPSS Statistics 23.0.</p><p><strong>Results: </strong>Claude 3 Opus achieved the highest accuracy (89%), significantly outperforming other LLMs and dermatologists (75%) (<i>P</i> < 0.05). ChatGPT 4o (79.6%) and ChatGPT 4 (78.1%) followed, with no significant differences observed among other LLMs or between LLMs and dermatologists (<i>P</i> > 0.05).</p><p><strong>Conclusion: </strong>This is the first study evaluating LLMs' performance on scabies-related knowledge. Claude 3 Opus' superior performance highlights its potential in dermatology, surpassing widely recognized LLMs like ChatGPT. Claude 3 Opus demonstrated exceptional accuracy in scabies-related queries, underscoring its value as adjunctive tool in dermatology. Enhancing LLMs' visual diagnostic capabilities is vital for their integration into clinical practice.</p>","PeriodicalId":13401,"journal":{"name":"Indian Journal of Dermatology","volume":"71 4","pages":"284-289"},"PeriodicalIF":1.7,"publicationDate":"2026-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13336648/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148436543","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Linear and Unilateral Basaloid Follicular Hamartoma Along Blaschko's Lines in an Elderly Patient: A Rare Presentation.","authors":"Pratiksha Mishra, Swatismita Sahoo, Subhransu K Hota, Lity Mohanty, Siddhartha Dash, Alaka Senapati","doi":"10.4103/ijd.ijd_1019_24","DOIUrl":"10.4103/ijd.ijd_1019_24","url":null,"abstract":"","PeriodicalId":13401,"journal":{"name":"Indian Journal of Dermatology","volume":"71 4","pages":"312-314"},"PeriodicalIF":1.7,"publicationDate":"2026-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13336547/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148436559","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"\"Actinic\" Conditions in Dermatology.","authors":"Youvalakshmi Saravanan, Vijayasankar Palaniappan, Kaliaperumal Karthikeyan","doi":"10.4103/ijd.ijd_803_24","DOIUrl":"10.4103/ijd.ijd_803_24","url":null,"abstract":"","PeriodicalId":13401,"journal":{"name":"Indian Journal of Dermatology","volume":"71 4","pages":"296-305"},"PeriodicalIF":1.7,"publicationDate":"2026-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13336549/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148436555","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Haemophagocytic Lymphohistiocytosis with Stevens-Johnson Syndrome Masquerading as Sepsis.","authors":"Bhagyashree B Supekar, Soudamini Tiwari, Pallavi J Yede, Jayesh I Mukhi","doi":"10.4103/ijd.ijd_607_24","DOIUrl":"10.4103/ijd.ijd_607_24","url":null,"abstract":"","PeriodicalId":13401,"journal":{"name":"Indian Journal of Dermatology","volume":"71 4","pages":"322-324"},"PeriodicalIF":1.7,"publicationDate":"2026-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13336530/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148436594","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Dysregulation of T Helper 17 Cell Pathway In Vitiligo.","authors":"Vaibhav Venkatesh, Deena Mendez, Rajashekar T Srinivas, Sharath Balakrishna","doi":"10.4103/ijd.ijd_577_24","DOIUrl":"10.4103/ijd.ijd_577_24","url":null,"abstract":"<p><strong>Background: </strong>Dysregulation of the T helper 17 (Th17) cell pathway can result in autoimmune activation and chronic inflammation. Vitiligo is an autoimmune disorder characterised by melanocyte cytotoxicity. The aim of this study was to examine the role of the Th17 pathway in the pathogenesis of vitiligo. The three components of the pathway were evaluated using plasma interleukin (IL6), IL23, and IL10 for the modulatory component, <i>STAT3</i> and <i>RORC</i> gene expression for the mediator component, and plasma IL17A for the effector component.</p><p><strong>Method: </strong>The study was carried out using a case-control design. The case group comprised patients diagnosed with vitiligo (<i>n</i> = 30), whereas the control group comprised healthy volunteers (<i>n</i> = 30). The plasma cytokine levels were measured by enzyme-linked immunosorbent assay. Gene expression in peripheral blood mononuclear cells was measured by real-time quantitative polymerase chain reaction.</p><p><strong>Results: </strong>In vitiligo patients, IL6 was 2.3 times higher (<i>P</i> < 0.001), IL23 was 1.1 times higher (<i>P</i> = 0.18), and IL10 was 2.5 times lower (<i>P</i> < 0.001). The fold change in the expression of the <i>STAT3</i> gene was 2.27 times (<i>P</i> < 0.01) and that of the <i>RORC</i> gene was 3.8 times (<i>P</i> < 0.001) in vitiligo patients. Plasma IL17A was 1.6 times higher (<i>P</i> < 0.001) in vitiligo patients.</p><p><strong>Conclusions: </strong>Together, these results indicate that the Th17 pathway is likely to be overactive in vitiligo due to dysregulation.</p>","PeriodicalId":13401,"journal":{"name":"Indian Journal of Dermatology","volume":"71 4","pages":"290-295"},"PeriodicalIF":1.7,"publicationDate":"2026-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13336544/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148436528","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}