Indian Journal of Dermatology最新文献_第5页

The Association of Leser-Trélat Sign with Cutaneous Undifferentiated Pleomorphic Sarcoma.

IF 1 4区医学

Indian Journal of Dermatology Pub Date : 2024-09-01 Epub Date: 2024-10-29 DOI: 10.4103/ijd.ijd_538_22

Hanan Ragragui Ouasmin, Hasna Saddouk, Youssef Joudeh Almheirat, Nada Zizi, Siham Dikhaye

引用次数: 0

Evaluating the Performance of ChatGPT in Dermatology Specialty Certificate Examination-style Questions: A Comparative Analysis between English and Korean Language Settings. 评估皮肤病学专业证书考试题型中 ChatGPT 的表现：英语和韩语语言环境的比较分析。

IF 1.7 4区医学

Indian Journal of Dermatology Pub Date : 2024-08-19 DOI: 10.4103/ijd.ijd_1050_23

Hae C Joh,Moon-Hwan Kim,Joo Y Ko,Joung S Kim,Mihn S Jue

引用次数: 0

Real-World Efficacy and Safety of Oral Tofacitinib in Patients with Refractory Moderate to Severe Atopic Dermatitis: A Multicenter Retrospective Study. 口服托法替尼对难治性中度至重度特应性皮炎患者的实际疗效和安全性：一项多中心回顾性研究

IF 1.7 4区医学

Indian Journal of Dermatology Pub Date : 2024-08-19 DOI: 10.4103/ijd.ijd_843_22

Sandipan Dhar,Abhishek De,Aarti Sarda,Kiran Godse,Koushik Lahiri

{"title":"Real-World Efficacy and Safety of Oral Tofacitinib in Patients with Refractory Moderate to Severe Atopic Dermatitis: A Multicenter Retrospective Study.","authors":"Sandipan Dhar,Abhishek De,Aarti Sarda,Kiran Godse,Koushik Lahiri","doi":"10.4103/ijd.ijd_843_22","DOIUrl":"https://doi.org/10.4103/ijd.ijd_843_22","url":null,"abstract":"BackgroundAtopic dermatitis (AD) has a complex etiology that includes Th2 polarization, which is accompanied by the cytokines IL4, IL-5, IL-13, and IL-31, as well as Th17 and Th22, and in chronic lesions, Th1 cells. Tofacitinib inhibits Th1-, Th2-, and Th17-associated cytokines by selectively blocking JAK1 and JAK3 receptors. We conducted a multicentric, retrospective chart analysis to study the efficacy and safety of tofacitinib in patients with moderate to severe refractory AD.Materials and MethodsWe included 16 adult patients (aged >18 years) with moderate to severe AD who had previously undergone systemic therapy with inadequate response. In the baseline, demographic data, previous treatment history, severity scores (eczema area and severity index [EASI] and SCORing Atopic Dermatitis [SCORAD]), and quality of life score (Dermatology Life Quality Index [DLQI]) were noted. Baseline blood investigations, including complete blood count, liver function test, renal function test, lipid profile, and interferon gamma release assay for tuberculosis, were done. Patients were followed up every month for 6 months that included documentation of severity scores, blood investigations, and DLQI. Any adverse events, if reported, were noted.ResultAll 16 patients completed the 6-month trial. Our patients were previously treated with cyclosporine (n = 10), methotrexate (n = 3), or both (n = 3). The mean EASI scores improved from 23.38 ± 9.56 at baseline to 8.50 ± 7.57 at the end of 6 months. The mean SCORAD score improved from 41.25 ± 8.69 at baseline to 14.93 ± 7.82 at the end of 6 months. Quality of life also improved as the mean DLQI improved from 15.18 ± 2.73 at baseline to 5.31 ± 4.11 at the end of the study period. No severe adverse reactions were noted, but 3 patients experienced dyslipidemia and 2 patients had altered bleeding time.ConclusionTofacitinib is a safe and effective treatment option for recalcitrant moderate to severe adult AD.","PeriodicalId":13401,"journal":{"name":"Indian Journal of Dermatology","volume":"100 1","pages":"292-295"},"PeriodicalIF":1.7,"publicationDate":"2024-08-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142264498","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

The Role of Dermoscopy and Teledermatology in a Case of Erythema Ab Igne Coexisting with Acute Radiation Dermatitis. 皮肤镜和远程皮肤学在一例急性放射性皮炎并存的 Ab Igne 红斑中的作用》（The Role of Dermoscopy and Teledermatology in a Case of Erythema Ab Igne Coexist with Acute Radiation Dermatitis）。

IF 1.7 4区医学

Indian Journal of Dermatology Pub Date : 2024-08-19 DOI: 10.4103/ijd.ijd_254_23

Basavaraju S Lakshmi,Shankar B Ashwini,P S S Ranugha,Garehatty R Kanthraj

引用次数: 0

Can Lichen Planus be a Forerunner of Paraneoplastic Pemphigus? 扁平苔癣会是副肿瘤性丘疹性荨麻疹的前身吗？

IF 1.7 4区医学

Indian Journal of Dermatology Pub Date : 2024-08-19 DOI: 10.4103/ijd.ijd_169_24

Twaseem Padiyath Mohamed,Sebastian Criton,Usha Mary Abraham

引用次数: 0

Sarcoidosis and Polymethyl Methacrylate (PMMA) Granulomas following COVID-19 Vaccination (ChAdOx1): Successful Treatment with Tofacitinib 接种 COVID-19 疫苗 (ChAdOx1) 后出现肉样瘤病和聚甲基丙烯酸甲酯 (PMMA) 肉芽肿：托法替尼的成功治疗

IF 1.7 4区医学

Indian Journal of Dermatology Pub Date : 2024-08-19 DOI: 10.4103/ijd.ijd_56_24

Mayra Ianhez, Hélio A Miot, Lívia VN Caetano, Henrique Moura de Paula, Giselle GS Freire, Pedro PTS Torres

{"title":"Sarcoidosis and Polymethyl Methacrylate (PMMA) Granulomas following COVID-19 Vaccination (ChAdOx1): Successful Treatment with Tofacitinib","authors":"Mayra Ianhez, Hélio A Miot, Lívia VN Caetano, Henrique Moura de Paula, Giselle GS Freire, Pedro PTS Torres","doi":"10.4103/ijd.ijd_56_24","DOIUrl":"https://doi.org/10.4103/ijd.ijd_56_24","url":null,"abstract":"<p>Sarcoidosis and complications related to fillers have been reported following the COVID-19 vaccination. Additionally, cutaneous sarcoidosis has been observed around polymethyl methacrylate (PMMA) injection sites. Foreign-body reactions to PMMA can occur simultaneously with systemic sarcoidosis, suggesting a shared pathogenic mechanism between both conditions. To report a case of sarcoidosis and PMMA granulomas following COVID-19 vaccination (ChAdOx11), successfully treated with tofacitinib. We present a 59-year-old woman who developed systemic sarcoidosis and a granulomatous reaction to PMMA filler following the COVID-19 vaccination (ChAdOx11). Notably, both PMMA and the vaccine were potential triggers for sarcoidosis. Treatment with tofacitinib produced marked improvement in both the cutaneous and pulmonary involvement of sarcoidosis and the granulomatous reaction to PMMA. This successful outcome suggests tofacitinib, a pan-JAK inhibitor, an alternative treatment for cutaneous and systemic sarcoidosis, as well as a potential therapy for granulomatous complications of dermal fillers, such as PMMA.</p>","PeriodicalId":13401,"journal":{"name":"Indian Journal of Dermatology","volume":"65 1","pages":""},"PeriodicalIF":1.7,"publicationDate":"2024-08-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142205765","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Patient Satisfaction with a Skin Cancer Tele-Triage System in the North of England. 英格兰北部患者对皮肤癌远程分诊系统的满意度。

IF 1.7 4区医学

Indian Journal of Dermatology Pub Date : 2024-08-19 DOI: 10.4103/ijd.ijd_816_23

Rui Baptista Gonçalves,Manu Shah

引用次数: 0

Association between Isotretinoin Exposure and Inflammatory Bowel Disease: A Nationwide Case-Control Study in South Korea. 异维A酸暴露与炎症性肠病之间的关系：韩国全国病例对照研究》。

IF 1.7 4区医学

Indian Journal of Dermatology Pub Date : 2024-08-19 DOI: 10.4103/ijd.ijd_644_23

Jin H Hyeong,Minkook Son,Dayeon Jeong,Ye J Jang,Kwang H Kim,Kwang J Kim,Eun J Park

{"title":"Association between Isotretinoin Exposure and Inflammatory Bowel Disease: A Nationwide Case-Control Study in South Korea.","authors":"Jin H Hyeong,Minkook Son,Dayeon Jeong,Ye J Jang,Kwang H Kim,Kwang J Kim,Eun J Park","doi":"10.4103/ijd.ijd_644_23","DOIUrl":"https://doi.org/10.4103/ijd.ijd_644_23","url":null,"abstract":"ContextIsotretinoin is commonly prescribed for the treatment of acne. However, its association with inflammatory bowel disease (IBD) could not be confirmed due to inconsistencies in the literature. Furthermore, no related study has been conducted on an Asian population.AimsThe aim of this study was to investigate the association between isotretinoin and inflammatory bowel disease.Methods and MaterialA nationwide, population-based, case-control study using the National Health Insurance Service database of South Korea was conducted. The case group comprised 107,434 patients with IBD, while the control group comprised 393,830 patients who were matched using a 1:4 propensity score. Data on isotretinoin exposure within the previous 5 years were extracted, and a multivariable-adjusted, conditional, logistic, regression analysis was performed.ResultsAfter adjusting for age, sex, underlying disease, the Charlson co-morbidity index, and tetracycline use, a significant association between isotretinoin exposure and IBD was found, with an odds ratio of 1.20 (95% confidence interval, 1.10-1.30). Furthermore, the association appeared to become stronger with longer exposure, more of a cumulative dose, and a longer time since the first exposure. When analyzed separately for ulcerative colitis and Crohn's disease, isotretinoin exposure was significantly associated with both diseases.ConclusionsOur study reveals a dose-response relationship between isotretinoin exposure and IBD risk in an Asian population. Healthcare professionals should be aware of the association and consider alternative medications for acne treatment, particularly in patients who are at a higher risk of developing IBD.","PeriodicalId":13401,"journal":{"name":"Indian Journal of Dermatology","volume":"13 1","pages":"301-305"},"PeriodicalIF":1.7,"publicationDate":"2024-08-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142264504","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Clinicomycological Pattern of Dermatophytosis in Odisha, a Coastal State of Eastern India. 印度东部沿海邦奥迪沙（Odisha）皮癣病的临床真菌学模式。

IF 1.7 4区医学

Indian Journal of Dermatology Pub Date : 2024-08-19 DOI: 10.4103/ijd.ijd_485_23

Sakshi Gaba,Kumudini Panigrahi,Hemanta K Kar,Mitanjali Sethy

{"title":"Clinicomycological Pattern of Dermatophytosis in Odisha, a Coastal State of Eastern India.","authors":"Sakshi Gaba,Kumudini Panigrahi,Hemanta K Kar,Mitanjali Sethy","doi":"10.4103/ijd.ijd_485_23","DOIUrl":"https://doi.org/10.4103/ijd.ijd_485_23","url":null,"abstract":"BackgroundDermatophytosis is a fungal infection that targets the skin and its appendages, such as the nails and hair. It affects all age groups and is estimated to affect approximately 20-25% of the population across the world. There are insufficient data on the clinic-mycological pattern of dermatophytosis in Odisha, a coastal state in eastern India. The study aims to explore the clinico-mycological pattern of prevailing superficial cutaneous fungal infections and to identify the specific species as per the site of skin involvement.MethodsThis is a cross-sectional study conducted in the Department of Dermatology in collaboration with the Department of Microbiology at a tertiary health care centre, Odisha, for a period of 2 years, from October 2020 to September 2022. Participants aged 18-65 years with active dermatophyte infections of the skin were included in the study. Clinical examination and mycological workup were performed, and the collected samples were divided into two parts, one for direct microscopy and the other for fungal culture.ResultsAccording to our study, the most common isolate was Trichophyton mentagrophytes (21.7%), followed by T. rubrum (11.7%), and 5.3% of cultures showed T. schoenleinii isolates, whereas Microsporum canis and Microsporum gypseum constituted 2.7% and 0.7%, respectively.ConclusionThe present study focuses on the prevalence and clinical trends of different dermatophyte species associated with dermatophytosis in eastern India. Due to the favourable climate of Odisha, superficial mycoses are prevalent here, and according to our study, Trichophyton mentagrophytes is the predominate isolate in this region.","PeriodicalId":13401,"journal":{"name":"Indian Journal of Dermatology","volume":"11 1","pages":"306-311"},"PeriodicalIF":1.7,"publicationDate":"2024-08-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142264494","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

A Gardner-Diamond Syndrome Accompanied by Complex Regional Pain Syndrome. 加德纳-钻石综合征伴有复杂区域疼痛综合征。

IF 1.7 4区医学

Indian Journal of Dermatology Pub Date : 2024-08-19 DOI: 10.4103/ijd.ijd_281_24

Emi Yokoyama,Yoshio Kawakami,Ayumi Okada,Masato Yashiro,Tomoko Tetsunaga,Shin Morizane

引用次数: 0