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Indian Journal of Dermatology最新文献

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A New Variant of the PTEN Gene in Relation to Cowden Syndrome Type 1. 与考登综合征 1 型有关的 PTEN 基因新变异。
IF 1 4区 医学
Indian Journal of Dermatology Pub Date : 2024-05-01 Epub Date: 2024-06-26 DOI: 10.4103/ijd.ijd_633_22
Marina Fernández-Villares, Isabel Villegas-Romero, Cristina Collantes-Rodríguez, Mario Linares-Barrios, Ana S Benito-Godino, Francisco Mora-Lopez
{"title":"A New Variant of the PTEN Gene in Relation to Cowden Syndrome Type 1.","authors":"Marina Fernández-Villares, Isabel Villegas-Romero, Cristina Collantes-Rodríguez, Mario Linares-Barrios, Ana S Benito-Godino, Francisco Mora-Lopez","doi":"10.4103/ijd.ijd_633_22","DOIUrl":"10.4103/ijd.ijd_633_22","url":null,"abstract":"","PeriodicalId":13401,"journal":{"name":"Indian Journal of Dermatology","volume":"69 3","pages":"274-276"},"PeriodicalIF":1.0,"publicationDate":"2024-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11305488/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141906498","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Desmoglein-1 Deficiency Mimicking Omenn Syndrome. 模仿奥门综合征的 Desmoglein-1 缺乏症
IF 1 4区 医学
Indian Journal of Dermatology Pub Date : 2024-05-01 Epub Date: 2024-06-26 DOI: 10.4103/ijd.ijd_1090_23
Meltem Comert, Tugba Guler, Ayca Ceylan, İlknur Kulhas Celik, Pinar Karabagli, Tulin Cora, Hasibe Artac
{"title":"Desmoglein-1 Deficiency Mimicking Omenn Syndrome.","authors":"Meltem Comert, Tugba Guler, Ayca Ceylan, İlknur Kulhas Celik, Pinar Karabagli, Tulin Cora, Hasibe Artac","doi":"10.4103/ijd.ijd_1090_23","DOIUrl":"10.4103/ijd.ijd_1090_23","url":null,"abstract":"","PeriodicalId":13401,"journal":{"name":"Indian Journal of Dermatology","volume":"69 3","pages":"283"},"PeriodicalIF":1.0,"publicationDate":"2024-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11305484/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141906555","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Parthenium Induced Pigmented Contact Dermatitis. Parthenium Induced Pigmented Contact Dermatitis.
IF 1 4区 医学
Indian Journal of Dermatology Pub Date : 2024-05-01 Epub Date: 2024-06-26 DOI: 10.4103/ijd.ijd_1027_23
Anand Mannu, Nishu Bala, Shekhar Neema, Santosh Kumar Battula
{"title":"Parthenium Induced Pigmented Contact Dermatitis.","authors":"Anand Mannu, Nishu Bala, Shekhar Neema, Santosh Kumar Battula","doi":"10.4103/ijd.ijd_1027_23","DOIUrl":"10.4103/ijd.ijd_1027_23","url":null,"abstract":"","PeriodicalId":13401,"journal":{"name":"Indian Journal of Dermatology","volume":"69 3","pages":"284"},"PeriodicalIF":1.0,"publicationDate":"2024-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11305513/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141906562","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
SDRIFE Induced by Tofacitinib. 托法替尼诱导的 SDRIFE。
IF 1 4区 医学
Indian Journal of Dermatology Pub Date : 2024-05-01 Epub Date: 2024-06-26 DOI: 10.4103/ijd.ijd_124_23
Ramachandran Gnanasuriyan, Savitha Murali, Remya Raj Rajamohanan, Sheela Kuruvila
{"title":"SDRIFE Induced by Tofacitinib.","authors":"Ramachandran Gnanasuriyan, Savitha Murali, Remya Raj Rajamohanan, Sheela Kuruvila","doi":"10.4103/ijd.ijd_124_23","DOIUrl":"10.4103/ijd.ijd_124_23","url":null,"abstract":"","PeriodicalId":13401,"journal":{"name":"Indian Journal of Dermatology","volume":"69 3","pages":"272-274"},"PeriodicalIF":1.0,"publicationDate":"2024-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11305504/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141906563","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
A Prospective Randomized Non-Blinded Study of Safety and Efficacy of Bilastine Up-Dosing (40 mg) Versus Combination of Bilastine 20 mg With Levocetirizine 5 mg in the Treatment of Chronic Spontaneous Urticaria. 比拉斯汀加量（40 毫克）与比拉斯汀 20 毫克和左西替利嗪 5 毫克联合用药治疗慢性自发性荨麻疹的安全性和有效性的前瞻性随机非盲法研究
IF 1 4区 医学
Indian Journal of Dermatology Pub Date : 2024-05-01 Epub Date: 2024-06-26 DOI: 10.4103/ijd.ijd_1199_23
Boggarapu Sneha, Murali Narasimhan, Priya Cinna T Durai, Ramachandran Ramakrishnan
{"title":"A Prospective Randomized Non-Blinded Study of Safety and Efficacy of Bilastine Up-Dosing (40 mg) Versus Combination of Bilastine 20 mg With Levocetirizine 5 mg in the Treatment of Chronic Spontaneous Urticaria.","authors":"Boggarapu Sneha, Murali Narasimhan, Priya Cinna T Durai, Ramachandran Ramakrishnan","doi":"10.4103/ijd.ijd_1199_23","DOIUrl":"10.4103/ijd.ijd_1199_23","url":null,"abstract":"<p><strong>Introduction: </strong>Chronic spontaneous urticaria (CSU) is the most commonly diagnosed skin condition in dermatology outpatient departments. Second-generation antihistamines are shown to be effective in the control of CSU. As per the guidelines, a combination of antihistamines is less recommended due to the lack of synergistic effect, though used widely. Exploring effective treatment options are crucial, given the challenges posed by CSU.</p><p><strong>Aims and objectives: </strong>To assess the safety and efficacy of Bilastine up-dosing versus combination of 20 mg Bilastine with 5 mg Levocetirizine in the treatment of CSU.</p><p><strong>Materials and methods: </strong>This prospective randomized non-blinded comparative trial involved 62 patients, with 32 in group A and 30 in group B. Group A received Tablet Bilastine 20 mg bd, while Group B received a combination of Tablet Bilastine 20 mg and Tablet Levocetirizine 5 mg. Urticarial Activity Score 7 was performed at baseline and follow-up visits (every 2 weeks for 6 weeks).</p><p><strong>Results: </strong>Both groups had a higher number of male patients in the 20-30 years age group. Angioedema was present in 15.6% of group A and 23.3% in group B. After 6 weeks, both the groups showed a significant improvement in UAS 7 scores (<i>P</i> value <0.05). Group A demonstrated a remarkable reduction in UAS 7 from 19.4% to 0.03% with minimal side effects.</p><p><strong>Conclusion: </strong>Bilastine up-dosing proved to be efficient, secure, and well tolerated when compared to the combined dose of Levocetirizine 5 mg and Bilastine 20 mg, suggesting that up-dosing of Bilastine could be a valuable addition to the current medication arsenal with the minimal side effects.</p>","PeriodicalId":13401,"journal":{"name":"Indian Journal of Dermatology","volume":"69 3","pages":"226-231"},"PeriodicalIF":1.0,"publicationDate":"2024-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11305495/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141906499","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Androgenetic Alopecia in Men: An Update On Genetics. 男性雄激素性脱发：遗传学最新进展
IF 1 4区 医学
Indian Journal of Dermatology Pub Date : 2024-05-01 Epub Date: 2024-06-26 DOI: 10.4103/ijd.ijd_729_23
Ilakkia Priya Sadasivam, Ravikumar Sambandam, Damayandhi Kaliyaperumal, Jude Ernest Dileep
{"title":"Androgenetic Alopecia in Men: An Update On Genetics.","authors":"Ilakkia Priya Sadasivam, Ravikumar Sambandam, Damayandhi Kaliyaperumal, Jude Ernest Dileep","doi":"10.4103/ijd.ijd_729_23","DOIUrl":"10.4103/ijd.ijd_729_23","url":null,"abstract":"<p><p>Androgenetic alopecia (AGA) is defined as the alopecia induced by androgens in genetically predisposed individuals. AGA results in progressive miniaturization of the hair follicles leading to vellus transformation of terminal hair. The high prevalence and wide range of expressed phenotypes in AGA is a result of a polygenic inheritance mode. The androgen receptor (AR) gene located on the X chromosome at Xq11-12 is the first gene to show genetic association with AGA. Newer genetic associations with AGA are under study. In early-onset AGA, obesity, diabetes, hypertension, dyslipidaemia, insulin resistance, benign prostatic hyperplasia (BPH), prostate cancers and coronary artery disease (CAD) are associated with AGA. Screening of early-onset AGA patients and intervention for metabolic syndrome and insulin resistance can prevent the development of cardiovascular disease (CVD) at an early stage. As effective treatments continue to be topical minoxidil, systemic finasteride and hair transplantations, newer modalities are under investigation. Understanding the genetic factors involved in AGA and continued research into newer therapies, such as cell-based therapies, will lead to effective treatment and improve the quality of life in patients with AGA.</p>","PeriodicalId":13401,"journal":{"name":"Indian Journal of Dermatology","volume":"69 3","pages":"282"},"PeriodicalIF":1.0,"publicationDate":"2024-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11305502/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141906502","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Generalized Asymptomatic Cutaneous Pits and Comedones in a Young Woman. 一名年轻女性全身无症状的皮肤凹陷和粉刺
IF 1 4区 医学
Indian Journal of Dermatology Pub Date : 2024-05-01 Epub Date: 2024-06-26 DOI: 10.4103/ijd.ijd_682_23
Keshavmurthy A Adya, Arun C Inamadar
{"title":"Generalized Asymptomatic Cutaneous Pits and Comedones in a Young Woman.","authors":"Keshavmurthy A Adya, Arun C Inamadar","doi":"10.4103/ijd.ijd_682_23","DOIUrl":"10.4103/ijd.ijd_682_23","url":null,"abstract":"","PeriodicalId":13401,"journal":{"name":"Indian Journal of Dermatology","volume":"69 3","pages":"284"},"PeriodicalIF":1.0,"publicationDate":"2024-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11305491/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141906557","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Important Roles of Interleukin-36, Interleukin-37, and Interleukin-38 Cytokines in the Pathogenesis of Rosacea. 白细胞介素-36、白细胞介素-37 和白细胞介素-38 细胞因子在红斑痤疮发病机制中的重要作用
IF 1 4区 医学
Indian Journal of Dermatology Pub Date : 2024-05-01 Epub Date: 2024-06-26 DOI: 10.4103/ijd.ijd_470_23
Alper Ekinci, Sevilay O Kilic, Nesrin Demir, Duygu Siddikoglu
{"title":"Important Roles of Interleukin-36, Interleukin-37, and Interleukin-38 Cytokines in the Pathogenesis of Rosacea.","authors":"Alper Ekinci, Sevilay O Kilic, Nesrin Demir, Duygu Siddikoglu","doi":"10.4103/ijd.ijd_470_23","DOIUrl":"10.4103/ijd.ijd_470_23","url":null,"abstract":"<p><strong>Background: </strong>Rosacea is a chronic inflammatory skin disease. Previous studies have determined that IL-36, IL-37, and IL-38 may play a role in the pathogenesis of various inflammatory diseases.</p><p><strong>Aims and objectives: </strong>The present study aims to evaluate the relationship of these cytokines with rosacea.</p><p><strong>Materials and methods: </strong>A total of 100 individuals, including 50 patients with rosacea and 50 healthy controls, were included in the study. IL-36, IL-37, and IL-38 levels were measured using the ELISA method by taking serum samples from all participants.</p><p><strong>Results: </strong>The mean serum levels of IL-36, IL-37, and IL-38 in the patient group were 52.17 ± 24.07 pg/ml, 18.46 ± 8.18 pg/ml, and 25.74 ± 8.36 ng/l, respectively. The mean serum levels of IL-36, IL-37, and IL-38 in the control group were 32.99 ± 19.90 pg/ml, 44.61 ± 22.27 pg/ml, and 45.61 ± 17.32 ng/l, respectively. The difference between the serum levels of IL-36, IL-37, and IL-38 in the patient and control groups was statistically significant (<i>P</i> < 0.001).</p><p><strong>Conclusion: </strong>Based on these findings, an increase in IL-36 and a decrease in IL-37 and IL-38 may contribute to the pathogenesis of rosacea. Future rosacea treatments could target and/or interact with these possible steps in the pathogenesis of rosacea.</p>","PeriodicalId":13401,"journal":{"name":"Indian Journal of Dermatology","volume":"69 3","pages":"232-237"},"PeriodicalIF":1.0,"publicationDate":"2024-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11305503/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141906560","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Multiple Whorled Keloidal Plaques in a Tea Plucker-Repeated Microtraumas Leading to Unique Morphology. 茶壶中的多重轮状瘢痕斑块--反复的微创伤导致独特的形态。
IF 1 4区 医学
Indian Journal of Dermatology Pub Date : 2024-05-01 Epub Date: 2024-06-26 DOI: 10.4103/ijd.ijd_109_24
Preema Sinha, Jatinder Singh, Archana Sharma
{"title":"Multiple Whorled Keloidal Plaques in a Tea Plucker-Repeated Microtraumas Leading to Unique Morphology.","authors":"Preema Sinha, Jatinder Singh, Archana Sharma","doi":"10.4103/ijd.ijd_109_24","DOIUrl":"10.4103/ijd.ijd_109_24","url":null,"abstract":"","PeriodicalId":13401,"journal":{"name":"Indian Journal of Dermatology","volume":"69 3","pages":"283"},"PeriodicalIF":1.0,"publicationDate":"2024-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11305509/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141906561","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Accessory Breast Cancer in the Right Axilla with Dermoscopic Images. 右侧腋窝的附属乳腺癌与皮肤镜图像。
IF 1 4区 医学
Indian Journal of Dermatology Pub Date : 2024-05-01 Epub Date: 2024-06-26 DOI: 10.4103/ijd.ijd_120_23
Takuma Matsunaga, Yuichi Yoshida, Takeshi Nakahara, Osamu Yamamoto
{"title":"Accessory Breast Cancer in the Right Axilla with Dermoscopic Images.","authors":"Takuma Matsunaga, Yuichi Yoshida, Takeshi Nakahara, Osamu Yamamoto","doi":"10.4103/ijd.ijd_120_23","DOIUrl":"10.4103/ijd.ijd_120_23","url":null,"abstract":"","PeriodicalId":13401,"journal":{"name":"Indian Journal of Dermatology","volume":"69 3","pages":"276-277"},"PeriodicalIF":1.0,"publicationDate":"2024-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11305494/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141906500","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
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