Indian Journal of Dermatology最新文献

{"title":"Metastatic Kaposi Sarcoma Masquerading as Tuberculosis: A Case Report.","authors":"Biju Vasudevan, Senkadhir Vendhan, Shekhar Neema, A W Kashif, Tilak Tvsvgk","doi":"10.4103/ijd.ijd_669_24","DOIUrl":"10.4103/ijd.ijd_669_24","url":null,"abstract":"","PeriodicalId":13401,"journal":{"name":"Indian Journal of Dermatology","volume":"71 2","pages":"152-155"},"PeriodicalIF":1.7,"publicationDate":"2026-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13012743/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147511878","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Pigmented Lesion in an Elderly Man: An Unusual Diagnosis.","authors":"Daniele C de Freitas Zernow, Hugo M Faver, Flávia P S C de Oliveira, Daniel L Obadia","doi":"10.4103/ijd.ijd_929_24","DOIUrl":"10.4103/ijd.ijd_929_24","url":null,"abstract":"","PeriodicalId":13401,"journal":{"name":"Indian Journal of Dermatology","volume":"71 2","pages":"165-166"},"PeriodicalIF":1.7,"publicationDate":"2026-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13012744/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147511942","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Clinical and Microbiological Profile of Recurrent and/or Persistent Cervicitis in Patients Attending Suraksha Clinic.","authors":"Anjali Sahu, Taru Garg, Ravinder Kaur, Vibhu Mendiratta, Manoj B Jais, Sanjib Gogoi","doi":"10.4103/ijd.ijd_658_24","DOIUrl":"10.4103/ijd.ijd_658_24","url":null,"abstract":"<p><strong>Background: </strong>Cervicitis is an inflammation of lower genital tract characterized by endocervical discharge and or bleeding and or >10 pus cells per high power field on microscopy. Its significance is its association with pelvic inflammatory disease. Various implicated organisms for cervicitis include Chlamydia trachomatis, Neisseria gonorrhoeae, Trichomonas vaginalis, Herpes simplex virus, Mycoplasma genitalium, and Ureaplasma species. Approximately 33% of cervicitis cases are recurrent and 18% may show persistence. Persistent or recurrent cervicitis despite antimicrobial therapy requires detailed evaluation. There is limited literature on the clinical and microbiological profile of such cases.</p><p><strong>Objective: </strong>To determine the clinical and microbiological profile of recurrent and/or persistent cervicitis in patients attending Suraksha clinic at a tertiary care centre.</p><p><strong>Methods: </strong>A cross-sectional study was conducted among 40 women aged 18-45 years with recurrent and/or persistent cervicitis, despite treatment. Detailed evaluation was done including history, examination, and investigations which did not give any clues regarding the etiology. Multiplex-PCR for various pathogens was done. Statistical analysis was performed using SPSS version 25.</p><p><strong>Results: </strong>Mean age of cases was 31.77 ± 6.99. Duration varied from <1 year to >5 years. All patients had >2 cervicitis episodes, with 15% reported persistent symptoms. High-risk behaviour was noted in 62.5%, with first sexual contact before 18 years in 42.5%, premarital contact in 10%, and history of other STIs in 25%. High-risk behaviour in partners was reported by 85%. Clinical presentation included cervicovaginal discharge (most common), dysuria, lower abdominal pain, and dyspareunia. Multiplex-PCR detected pathogens in 70% of cases (gardnerella: 47.5%, ureaplasma: 40%, trichomonas: 5%, chlamydia: 2.5%, mixed infections: 22.5%). Higher pus cell counts correlated significantly with detection of one or more organism.</p><p><strong>Conclusion: </strong>This study highlights the complexity of etiology of recurrent/persistent cervicitis identifying gardnerella and ureaplasma as predominant associated organisms. Multiplex-PCR is a valuable tool to provide insights into such difficult-to-treat cervicitis cases. Large studies with controls are required to verify findings of our study.</p>","PeriodicalId":13401,"journal":{"name":"Indian Journal of Dermatology","volume":"71 2","pages":"169"},"PeriodicalIF":1.7,"publicationDate":"2026-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13012750/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147511958","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Dermoscopic Features of Porocarcinoma: Report of 11 Cases and Review of the Literature.","authors":"Kodai Miyamoto, Teruki Yanagi, Takuya Maeda, Keiko Tokuchi, Che Yuan Hsu, Hideyuki Ujiie","doi":"10.4103/ijd.ijd_455_24","DOIUrl":"10.4103/ijd.ijd_455_24","url":null,"abstract":"<p><p>Porocarcinoma is a rare skin cancer that originates in cutaneous intraepidermal ducts of the sweat glands. Although dermoscopy is often helpful to make a diagnosis of skin tumors such as melanoma, dermoscopic features of porocarcinoma have not been investigated in detail. We aimed to identify dermoscopic features of porocarcinoma and to determine if they are distinguishable from other diseases. We examined the dermoscopic features of 11 cases of porocarcinoma, which were diagnosed using histopathological observations. Also, we reviewed previous case reports describing dermoscopic characteristics of porocarcinoma. Pink-white structureless areas were observed focally in all 11 cases. Ten cases showed polymorphous vascular patterns, in which two or more vascular patterns, such as linear-irregular, glomerular, dotted, and hairpin vessels, were present. None of the leaf-like vessels, coiled vessels, arborizing vessels, comedo-like openings, milia-like cysts, cerebriform patterns, or pigment networks were observed in any cases. In the previously reported 14 cases of porocarcinoma, the \"white-to-pink halo\" and the \"polymorphous vascular pattern\" were the most frequent dermoscopic findings (13 cases). \"Pink-white structureless areas\" was the third most common finding (11 cases). In cases displaying polymorphous vascular patterns, the main component was linear-irregular vessels (9 cases). Our 11 and 14 reported cases suggest that \"pink-white structureless areas\" together with \"polymorphous vascular patterns\" should be considered critical dermoscopic features of porocarcinoma. The findings could be helpful to distinguish porocarcinoma from tumors like eccrine poroma.</p>","PeriodicalId":13401,"journal":{"name":"Indian Journal of Dermatology","volume":"71 2","pages":"145-150"},"PeriodicalIF":1.7,"publicationDate":"2026-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13012749/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147511890","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"A Record-Based Retrospective Study of Histopathological Evaluation of Non-Lepromatous Cutaneous Infections in a Tertiary Care Institute.","authors":"Kalaivani Selvi Subramanian, SreeRekha Jinkala, Debasis Gochhait, Srinivas Bheemanathi Hanuman","doi":"10.4103/ijd.ijd_98_24","DOIUrl":"10.4103/ijd.ijd_98_24","url":null,"abstract":"<p><strong>Introduction: </strong>Cutaneous infections contribute to an important cause of all dermatological lesions. Most of the superficial cutaneous infections are diagnosed based on clinical findings and with adjunct diagnostic modalities like potassium hydroxide mounts, tzanck smears, Gram stain, and other microbiological investigations and are treated without the necessity of histopathological examinations. Histopathology is indispensable in some instances, especially when the above-mentioned investigations are non-contributory for diagnosis, and in situations where there is a doubt that the organisms isolated in culture represents contamination and in deep cutaneous infections to define tissue and vascular invasion. Hence, this study aimed at studying the spectrum of non-lepromatous cutaneous infections that required histopathological examination for diagnosis.</p><p><strong>Materials and methods: </strong>This is a record-based retrospective study conducted in the Department of Pathology for 4 years. All diagnosed cases of cutaneous infections that required histopathological examinations for diagnosis were included in the study. Leprosy cases were excluded from the study. Details were collected retrospectively from the records and were analysed manually. Results: There were totally 112 cases of cutaneous infections diagnosed on histopathology during the study period, of which 14% were bacterial, 15.2% were viral, 77% were fungal, and 3.6% were parasitic. Actinomycosis was the common bacterial infection, human papillomavirus-related lesions were the common viral infections, pheohyphomycosis was the common fungal infection, and cysticercosis was the common parasitic infection.</p><p><strong>Conclusion: </strong>Histopathological examinations play an important role in management of cutaneous infections as they not only aid in primary diagnosis but also give information on host reaction, severity of the infection, and the presence of tissue invasion, which are crucial information for undertaking treatment decisions.</p>","PeriodicalId":13401,"journal":{"name":"Indian Journal of Dermatology","volume":"71 2","pages":"115-119"},"PeriodicalIF":1.7,"publicationDate":"2026-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13012745/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147511828","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Efficacy of Intense Pulsed Light Treatment in Melasma.","authors":"Ayda Acar, Ilgen Ertam Sagduyu","doi":"10.4103/ijd.ijd_49_25","DOIUrl":"10.4103/ijd.ijd_49_25","url":null,"abstract":"<p><p>Melasma is a challenging pigmentation disorder for both the patient and the physician, particularly due to its frequent recurrences and resistance to standard therapies. Light and laser-based treatments are generally preferred when the condition is resistant to topical treatments. Intense pulsed light (IPL) is a light therapy that is both effective for epidermal and dermal melasma as well as vascular components, due to its broad range of energy. Compared to lasers and other energy-based devices, IPL offers broader wavelength coverage, deeper penetration, and the capacity to treat larger surface areas with reduced risk of collateral tissue damage. In this review, we will discuss about IPL mechanism in melasma and studies in the literature about IPL efficacy in melasma including its use as monotherapy and in combination with other modalities. While IPL monotherapy shows moderate improvement, the literature predominantly consists of combination therapy studies, limiting the ability to isolate IPL's direct effectiveness. Future prospective studies with standardized protocols and extended follow-up are needed to define IPL's optimal role in the management of melasma.</p>","PeriodicalId":13401,"journal":{"name":"Indian Journal of Dermatology","volume":"71 1","pages":"51-54"},"PeriodicalIF":1.3,"publicationDate":"2026-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12830011/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"146051941","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Pemphigus Vulgaris Successfully Treated with Belimumab: A Case Report.","authors":"Lin Zheng, Yuan Si, Xining She, Ruihua Fang","doi":"10.4103/ijd.ijd_599_24","DOIUrl":"10.4103/ijd.ijd_599_24","url":null,"abstract":"","PeriodicalId":13401,"journal":{"name":"Indian Journal of Dermatology","volume":"71 1","pages":"75-77"},"PeriodicalIF":1.3,"publicationDate":"2026-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12830025/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"146051967","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Pediatric Psoriasis: A Peek into the Comorbidity Profile.","authors":"Sharang Gupta, Seema Goel, Dimple Chopra, Shreya Malhan, Amitoj Singh Sidhu","doi":"10.4103/ijd.ijd_752_24","DOIUrl":"10.4103/ijd.ijd_752_24","url":null,"abstract":"<p><strong>Background: </strong>Psoriasis is a multifactorial immune-mediated inflammatory disorder in which the involvement of the skin is merely the tip of the iceberg. It poses a significant global problem affecting both children and adults, with childhood onset occurring in almost one-third of the cases. Early diagnosis of pediatric psoriasis is crucial to address, identify, and manage the growing list of established extracutaneous manifestations and comorbidities.</p><p><strong>Aims and objectives: </strong>To study the clinico-epidemiological profile of pediatric psoriasis and determine the prevalence of various comorbidities associated with it.</p><p><strong>Materials and methods: </strong>This was a cross sectional observational study conducted at the Department of Dermatology of a tertiary care hospital of North India over a period of 36 months and included all patients aged 9 months to 18 years with a clinical diagnosis of psoriasis. A predesigned structured proforma was used to collect the required information from the study subjects.</p><p><strong>Results: </strong>Eighty-six patients were recruited in this study, of which 47 (54.65%) were males and 39 (45.34%) were females. The most common type of psoriasis seen in this study was chronic plaque psoriasis (63%). Eight (9.30%) patients had evidence of psoriatic arthritis at presentation. Abnormal waist circumference was observed in 26 (30.23%) of the 86 patients recruited in the study. Abnormal BMI was recorded in 49 (56.97%) patients, of which 27 (31.39%) were overweight and 22 (25.58%) were obese. Ten (11.62%) patients had evidence of impaired fasting glucose, while 1 (1.16%) patient had type 2 diabetes mellitus. Increased levels of total cholesterol were observed in 13 (15.11%) patients involved in the study. Fifty-nine (68.60%) patients had at least 1 lipid profile abnormality. Eight (9.30%) participants fulfilled the criteria for metabolic syndrome. Concomitant autoimmune diseases were seen in 42 (48.83%) patients, of which hypothyroidism was the most common, followed by vitiligo, alopecia areata, type 1 diabetes mellitus, systemic lupus erythematosus, and juvenile rheumatoid arthritis.</p><p><strong>Conclusion: </strong>Although the association between psoriasis and various comorbidities is well documented in adults, studies demonstrating the same relationship in children are still lacking. However, psoriasis begins in childhood or adolescence in approximately 40% of patients, suggesting that the risk of comorbidities may also begin early in life. This presents an opportunity for prevention, early detection, and intervention for children who may suffer from or be at a risk of comorbidities, especially metabolic ones.</p>","PeriodicalId":13401,"journal":{"name":"Indian Journal of Dermatology","volume":"71 1","pages":"12-17"},"PeriodicalIF":1.3,"publicationDate":"2026-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12830020/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"146046141","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Verrucous Hemangioma: A New Mode of Presentation with Literature Review.","authors":"Khalil I Alhamdi, Dooha K Alhamdi, Rand A Almuhyi","doi":"10.4103/ijd.ijd_153_23","DOIUrl":"10.4103/ijd.ijd_153_23","url":null,"abstract":"","PeriodicalId":13401,"journal":{"name":"Indian Journal of Dermatology","volume":"71 1","pages":"71-73"},"PeriodicalIF":1.3,"publicationDate":"2026-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12830009/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"146046380","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Hypergranulotic Dyscornification - Alba Variant.","authors":"C K SriRam, A S Krishnaram, I Shibani, Sri Krishna Priya","doi":"10.4103/ijd.ijd_405_23","DOIUrl":"10.4103/ijd.ijd_405_23","url":null,"abstract":"<p><p>Hypergranulotic dyscornification (HGD) represents a unique histopathologic reaction pattern with disorder in the maturation of corneocytes. Hypergranulotic dyscornification do not have specific clinical description so final diagnosis is entirely based on histological findings. A 69 yrs old man presented with multiple asymptomatic discrete depigmented papules and nodules with verrucous surface over the legs and hands of 3 months duration. Verruca vulgaris and seborrheic keratosis were provisional diagnosis based on surface verrucosity but could not explain the depigmentation. Histopathology revealed features of HGD. Special stain with Fontana Masson and immunohistochemistry with HMB-45 showed loss of melanocytes in lesional skin compared to normal skin which explained depigmentation. This case of HGD is reported for its rarity and additional finding of depigmentation which has not been reported so far in the literature. The diagnosis of HGD Albicans or with co-occurrence of vitiligo remains to be seen with further reports.</p>","PeriodicalId":13401,"journal":{"name":"Indian Journal of Dermatology","volume":"71 1","pages":"85"},"PeriodicalIF":1.3,"publicationDate":"2026-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12830027/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"146051912","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}