窄带紫外线B光疗治疗老年银屑病7年回顾性研究。

IF 1 4区医学 Q4 DERMATOLOGY

Indian Journal of Dermatology Pub Date : 2025-03-01 Epub Date: 2025-02-27 DOI:10.4103/ijd.ijd_184_23

Lili Legiawati, Rinadewi Astriningrum, Shannaz N Yusharyahya, Vivianne Chandrakesuma, Andria A Pulungan

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引用次数: 0

摘要

背景：银屑病的并发症可能会增加老年患者退行性疾病的负担。光疗是银屑病成熟的治疗方法，窄带紫外线B （NB-UVB）是目前银屑病的一线光疗。它在老年人中的使用已被评估，并发现对许多皮肤病是安全有效的。目的：了解NB-UVB光疗在印尼老年牛皮癣患者中的疗效和安全性。材料与方法：回顾性研究2014-2020年在Cipto Mangunkusumo国立综合医院皮肤性病门诊接受NB-UVB光疗的≥60岁银屑病患者的病历资料。数据采用SPSS version 25进行处理，并进行描述性分析。结果：在30例患者中，14例患者（47%）在中位21次治疗和中位累积剂量为25.7 J/cm2后，牛皮癣面积和严重程度指数减少了75%。9名患者（30%）出现了副作用，包括疼痛、灼烧和瘙痒。在治疗期间，没有患者经历两次以上的红斑发作。大多数副作用是轻微的，不需要停止治疗。结论：NB-UVB光疗治疗老年银屑病安全有效。

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A 7-Year Retrospective Study of Narrowband Ultraviolet B Phototherapy for Psoriasis in Geriatric Patients.

Background: Complications of psoriasis may add to the burden of degenerative diseases already present in elderly patients. Phototherapy is a well-established treatment for psoriasis, and narrowband ultraviolet B (NB-UVB) is currently the first-line phototherapy for psoriasis. Its use in elderly has been assessed and is found to be safe and efficacious for many dermatoses.

Aims and objectives: To learn the efficacy and safety of NB-UVB phototherapy in geriatric patients with psoriasis in Indonesia.

Materials and methods: A retrospective study using data from medical records of psoriasis patients aged ≥60 who received NB-UVB phototherapy at the dermatovenereology outpatient clinic of Dr. Cipto Mangunkusumo National General Hospital in 2014-2020. The data were processed using SPSS version 25, and descriptive analysis was conducted.

Results: From 30 patients, 75% reduction of Psoriasis Area and Severity Index was accomplished by 14 patients (47%) after a median of 21 sessions and a median cumulative dose of 25.7 J/cm2. The side effects were experienced by nine patients (30%), comprising pain, burn, and itch. No patient experienced more than two episodes of erythema during their treatment. Most side effects are mild and do not require discontinuation of therapy.

Conclusions: NB-UVB phototherapy is safe and effective for geriatric patients with psoriasis.

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来源期刊

Indian Journal of Dermatology Medicine-Dermatology

CiteScore

1.80

自引率

0.00%

发文量

217

审稿时长

47 weeks

期刊介绍： The journal publishes information related to skin-pathology and different modes of therapeutics, including dermatosurgery and cosmetic dermatology. Likewise, it carries articles on leprosy, STI and HIV/AIDS. The editorial board encourages the authors to publish articles addressing emerging techniques and developments in the subject specialty, in the form of Original investigations, Narrative and Systematic Reviews as well as Case Reports. The journal aims at publishing Editorials and Commentaries from eminent personalities on a regular basis.