Indian heart journal最新文献

{"title":"Acute changes in left atrial appendage function with premature ventricular complexes","authors":"Suresh Kumar Sukumaran,&nbsp;Anish Bhargav,&nbsp;Sridhar Balaguru,&nbsp;Avinash Anantharaj,&nbsp;Santhosh Satheesh,&nbsp;Raja J. Selvaraj","doi":"10.1016/j.ihj.2025.05.001","DOIUrl":"10.1016/j.ihj.2025.05.001","url":null,"abstract":"<div><h3>Objectives</h3><div>Left atrial appendage (LAA) dysfunction is a risk factor for stroke. Evidence shows that frequent premature ventricular complexes (PVCs) are associated with embolic stroke. Whether left atrial dysfunction is the bridging link between frequent premature ventricular complexes and stroke is unknown.</div></div><div><h3>Materials and methods</h3><div>Patients with a structurally normal heart undergoing elective electrophysiology study were included. Transoesophageal echo was used to measure LAA flow velocities. To simulate PVCs in bigeminal rhythm, single paced beats were delivered from the right ventricle with a coupling interval of QT + 10 % RR interval after each sinus beat. LAA flow doppler velocities were acquired at baseline, after 5 min of pacing and again 5 min after cessation of pacing.</div></div><div><h3>Results</h3><div>Ten patients were included in the study. Late diastolic emptying velocity decreased significantly after 5 min of PVCs (55.68 ± 16.33 cm/s, <em>p</em> = 0.01) compared to baseline (68.01 ± 10.34 cm/s). This almost returned to baseline after a rest period of 5 min (63.13 ± 16.16 cm/s, <em>p</em> = 0.277). The left atrial appendage filling velocity exhibited a statistically non-significant trend toward a decrease after 5 min of PVCs (45.70 ± 10.85 cm/s, <em>p</em> = 0.129), compared to the baseline value of 51.31 ± 14.11 cm/s.</div></div><div><h3>Conclusions</h3><div>Premature ventricular complexes in bigeminal pattern for 5 min resulted in an acute decrease in the late diastolic emptying velocity. This is a possible mechanism for the increased risk of strokes in patients with frequent PVCs.</div></div>","PeriodicalId":13384,"journal":{"name":"Indian heart journal","volume":"77 3","pages":"Pages 159-163"},"PeriodicalIF":1.4,"publicationDate":"2025-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143981794","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Emerging role of angiotensin receptor neprilysin inhibitor in right ventricular systolic dysfunction with preserved left ventricular ejection fraction","authors":"Ertan Yetkin","doi":"10.1016/j.ihj.2025.05.005","DOIUrl":"10.1016/j.ihj.2025.05.005","url":null,"abstract":"","PeriodicalId":13384,"journal":{"name":"Indian heart journal","volume":"77 3","pages":"Page 252"},"PeriodicalIF":1.4,"publicationDate":"2025-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144005611","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"A study of intracoronary thrombolytic agents in high thrombus burden lesions during primary PCI","authors":"Venkata RS. Subrahmanya Sarma,&nbsp;K. Gopalakrishna,&nbsp;K. Purnachandra Rao,&nbsp;G. Somasekahr,&nbsp;P.S.S. Chowdary,&nbsp;P. Raghuram,&nbsp;B. Dasarath,&nbsp;Manohar Reddy,&nbsp;Ramkishore,&nbsp;Raji Veeramachineni,&nbsp;Y. Sasidhar,&nbsp;M. Prasad","doi":"10.1016/j.ihj.2025.01.008","DOIUrl":"10.1016/j.ihj.2025.01.008","url":null,"abstract":"<div><h3>Objectives</h3><div>High thrombus burden during Primary Percutaneous Coronary Intervention begets poor outcomes; there are several lacunas in the management of those patients.- The purpose of this study is to analyse the long-term outcomes of patients undergoing primary percutaneous coronary intervention with high thrombus burden, treated with intracoronary thrombolysis as an adjunctive therapy.</div></div><div><h3>Methods</h3><div>In this prospective observational study, 108 consecutive primary percutaneous coronary intervention patients with high thrombus burden were stratified into two groups basing on whether they received intracoronary thrombolytic agent before stent implantation. The primary outcome is Net Adverse Clinical Events. Secondary outcomes include Major Adverse Cardiac Events, and all other individual components of the Net Adverse Clinical Events when analysed separately.</div></div><div><h3>Results</h3><div>The primary outcome events occurred in 21 patients (26 %) in the Primary stent group (<em>n</em> = 80), whereas it occurred in 2 patients (6 %) in the primary intra-coronary thrombolysis group (<em>n</em> = 28), this study shows that there is no difference in primary endpoints in both groups (26 % Vs 7 %, <em>p</em>-value – .042, Hazard ratio - 2.56; 95 % CI - .76–8.57), however Kaplan–Meier event-free survival curves show that both the curves are well separated apart even at the end of the one year of follow – up.</div></div><div><h3>Conclusion</h3><div>There is no difference in the primary outcome events in both groups, however there was a consistent increase in events in the primary stent group over the one-year follow-up period. These findings suggest the need for a larger randomized clinical trial to confirm and further elucidate these results.</div></div>","PeriodicalId":13384,"journal":{"name":"Indian heart journal","volume":"77 3","pages":"Pages 193-198"},"PeriodicalIF":1.4,"publicationDate":"2025-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143074301","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Fate of mitral regurgitation after transcatheter closure of patent ductus arteriosus: single centre study","authors":"Gayathri Bhuvaneswaran Kartha,&nbsp;Shruti Irene Varghese,&nbsp;Jesu Krupa,&nbsp;Anoop George Alex,&nbsp;Oommen K. George,&nbsp;Viji Samuel Thomson","doi":"10.1016/j.ihj.2025.04.001","DOIUrl":"10.1016/j.ihj.2025.04.001","url":null,"abstract":"<div><div>A hemodynamically significant patent ductus arteriosus (PDA) may be associated with mitral regurgitation (MR). Available treatment strategies are - surgical PDA ligation ± mitral valve surgery and initial transcatheter PDA closure (PDA-DC) with treatment of MR subsequently, if necessary. We aimed to describe the fate of MR after PDA-DC in patients with PDA and significant MR. On retrospective review of electronic health records between 2013 and 2023, 14 eligible patients were identified. Amongst them, PDA-DC resulted in symptomatic improvement in all. A reduction in the severity of MR was noted in 12 patients (85.7 %).</div></div>","PeriodicalId":13384,"journal":{"name":"Indian heart journal","volume":"77 3","pages":"Pages 231-234"},"PeriodicalIF":1.4,"publicationDate":"2025-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143795452","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Very early discharge of LOw-Risk ST elevation myocardial infarction patients after successful primary percutaneous coronary intervention (VEDLOR-STEMI) study.","authors":"Refai Showkathali, Radhapriya Yalamanchi, Aishwarya Mahesh Kumar, Sengottuvelu Gunasekaran, Abraham Oomman","doi":"10.1016/j.ihj.2025.04.002","DOIUrl":"10.1016/j.ihj.2025.04.002","url":null,"abstract":"<p><p>This VEDLOR-STEMI study assessed the safety and efficacy of very-early discharge (VED- ≤ 48 h) after primary percutaneous coronary intervention (PPCI) for patients with ST elevation myocardial infarction who are considered low risk and compared their outcome with low-risk patients who had standard discharge protocol. No major adverse cardiac events (MACCE) occurred within 6 months. Minor complications, like access site pain were managed without readmission. High patient satisfaction (97.3 %) was noted, with 48 % actively utilizing a hotline for queries. VED post-PPCI appears feasible and safe with appropriate discharge protocols and follow-up.</p>","PeriodicalId":13384,"journal":{"name":"Indian heart journal","volume":" ","pages":""},"PeriodicalIF":1.4,"publicationDate":"2025-04-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143994535","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Utility of ¹⁸F-FDG PET/CT and Cardiac MRI in early Cardiac Sarcoidosis.","authors":"Muthiah Subramanian, Bharat Narasimhan, Radhika Korabathina, Suneetha Batchu, Vishnu Vardhan Ravilla, Mohan Roop, Sachin Yalagudri, Daljeet Kaur Saggu, Calambur Narasimhan","doi":"10.1016/j.ihj.2025.03.007","DOIUrl":"10.1016/j.ihj.2025.03.007","url":null,"abstract":"<p><strong>Background and aims: </strong>Although ¹⁸F-FDG-PET/CT and CMR are commonly used to diagnose cardiac sarcoidosis(CS), their clinical utility in early-vs. late-stage disease is unclear. The objective of this study was to compare the diagnostic utility of 18-fluorodeoxyglucose positron emission tomography/computed tomography(¹⁸F-FDG-PET/CT) and cardiac magnetic resonance imaging(CMR) in patients with early- and late-stage CS.</p><p><strong>Methods: </strong>Data of 110 consecutive patients with biopsy-proven CS from the Granulomatous Myocarditis Registry were analyzed. All patients underwent ¹⁸F-FDG0PET/CT and CMR within 2 weeks of initial clinical presentation. Patients were divided into early-(<6 months) and late-stage groups based on the time since their first cardiac presentation. Myocardial uptake and late gadolinium enhancement(LGE) were qualitatively and quantitatively assessed. Complete clinical, echocardiographic, and radiological responses were assessed after 4-6 months of immunosuppressive therapy(IST).</p><p><strong>Results: </strong>Among the 102 patients in the final analysis(44.1 ± 10.3 years; LV ejection fraction[LVEF], 43.1 ± 9.5 %),54.9 % and 45.6 % received early and late diagnosis, respectively. Abnormal myocardial uptake on ¹⁸F-FDG-PET/CT 100 %) was observed in all patients with early CS, while only 73.2 % showed LGE on CMR(p < 0.001). The diagnostic yield of ⁸F-FDG-PET/CT and CMR was similar in late CS(91.3 %vs.97.8 %,p = 0.498). Patients with early CS had a higher myocardial SUV_max and more extensive LV involvement than those with late CS. Complete response to IST was more common in patients with early CS than in those with late CS(62.5 %vs.47.8 %,p = 0.019). In the early CS cohort, patients without LGE had a higher rate of complete response following IST than those with LGE (86.7 %vs.53.7 %,p = 0.025).</p><p><strong>Conclusion: </strong>In patients with early CS,¹⁸F-FDG-PET/CT appears to be more sensitive and useful than CMR for diagnosis and assessment of response to IST.</p>","PeriodicalId":13384,"journal":{"name":"Indian heart journal","volume":" ","pages":""},"PeriodicalIF":1.4,"publicationDate":"2025-03-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143639559","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Implementation of a hub and spoke STEMI Goa project – Initial results, gains and challenges","authors":"Guruprasad Naik ,&nbsp;Amar Prabhudesai ,&nbsp;Venkatesh Malali ,&nbsp;Michelle Viegas Parab ,&nbsp;Joel Quadros ,&nbsp;Pankajam Vaidya ,&nbsp;Edward D'Mello ,&nbsp;Swapnil Arsekar ,&nbsp;Radha Valaulikar","doi":"10.1016/j.ihj.2025.02.004","DOIUrl":"10.1016/j.ihj.2025.02.004","url":null,"abstract":"<div><h3>Objectives</h3><div>To study the impact of a ‘hub and spoke’ STEMI management programme on delivery of thrombolysis in the state of Goa.</div></div><div><h3>Methods</h3><div>A prospective observational study was conducted to assess the ‘hub and spoke’ model STEMI programme in the state of Goa. Data was collected using predesigned proformas filled at Primary Health Centres or District Hospitals which served as the spokes. Primary programme efficacy outcomes studied were the proportion of eligible patients of STEMI receiving thrombolysis and the time to thrombolysis. Secondary outcome assessed was in-hospital mortality.</div></div><div><h3>Results</h3><div>A total of 2050 number of patients were diagnosed with STEMI between November 2019 and March 2022, of which complete data was available for 1325 patients. After ruling out contraindications, delayed presentations or refusal for treatment, 74.3 % of STEMI patients received thrombolysis. The median window period was 130.83 min with an interquartile range (IQR) of 159.63 min. The median time from presentation to recording ECG was 7.9 (IQR = 11.63) minutes and presentation to cloud diagnosis was 11.78 (IQR = 12.96) minutes. The median time from presentation to administering thrombolysis (Door to Needle time) was 18.48 (IQR = 28.85) minutes. Only 0.22 % patients received inappropriate thrombolysis and the in-hospital mortality was 9.4 %.</div></div><div><h3>Conclusion</h3><div>A STEMI programme utilizing the existing manpower and primary health care setup improved ‘secondary’ level of care to patients by providing thrombolysis to a high percentage of patients in quick time. This may serve as a model to improve the outreach of reperfusion therapy in a resource challenged country like India.</div></div>","PeriodicalId":13384,"journal":{"name":"Indian heart journal","volume":"77 2","pages":"Pages 67-72"},"PeriodicalIF":1.4,"publicationDate":"2025-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143414071","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Study of fluoroscopic landmarks in IVUS guided zero contrast PCI - A single centre experience","authors":"Uday B. Khanolkar ,&nbsp;Pankaj Banotra ,&nbsp;Bijay Kumar Mahala ,&nbsp;Nitin Kumar Hegde ,&nbsp;Blessvin Jino ,&nbsp;Devi Prasad Shetty ,&nbsp;Parin Chandrakant Sangoi","doi":"10.1016/j.ihj.2025.02.006","DOIUrl":"10.1016/j.ihj.2025.02.006","url":null,"abstract":"<div><h3>Introduction</h3><div>Contrast induced nephropathy is third most common cause of renal insufficiency following percutaneous coronary angioplasty (PCI) and patients with preexisting renal dysfunction are even at a higher risk for poor outcomes. With the advent of intravascular imaging, safety and efficacy of angioplasty can be improved significantly in these patients.</div></div><div><h3>Material and methods</h3><div>This observational prospective study included 72 consecutive patients with CKD(eGFR ≤45 ml/min/m²) and established CAD who underwent absolute zero contrast PCI at a single tertiary center.PCI was planned in patients with significant stenosis and indications for revascularization.All Procedures were performed under dry fluoroscopy and IVUS guidance without use of any contrast.Informed consent, clinical,procedural and follow-up data was collected and analysed.</div></div><div><h3>Results</h3><div>Total 72 patients (90 vessels) with median age of 63 years and eGFR (34.1 ml/min/1.73 m²) underwent zero contrast PCI. Procedure was performed by Femoral (45.6 %)and radial (54.4%) route. Total 11 patients (15.3%) underwent left main stenting. Fluoroscopic landmarks such as side-branch wiring (71.1%),floating wire in aorta (22.2 %), calcifications (21.1%), bony landmarks such as ribs or vertebrae (45.5%) and Sternal wires/clips (6.6%) were used in addition to IVUS to enable more accurate placement of stent.Technical and procedural success were achieved in 91.1% and 97.2% of patients.One patient died in hospital due to non-cardiac cause and one patient required hemodialysis.Post procedure at 48 hrs, there was no deterioration of renal function.On 3 months followup, there was no significant major adverse cardiovascular events (MACE).</div></div><div><h3>Conclusion</h3><div>Our study shows that with the help of fluoroscopy landmarks and intravascular imaging, zero contrast PCI can be performed safely with good clinical outcomes in patients at risk of nephropathy.</div></div>","PeriodicalId":13384,"journal":{"name":"Indian heart journal","volume":"77 2","pages":"Pages 78-83"},"PeriodicalIF":1.4,"publicationDate":"2025-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143472470","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"The diastolic duration as a percentage of the cardiac cycle in healthy adults: A pilot study","authors":"Neeta Bachani ,&nbsp;Soorampally Vijay ,&nbsp;Aniruddha Vyas ,&nbsp;Jaipal Jadwani ,&nbsp;Gopikrishna Panicker ,&nbsp;Yash Lokhandwala","doi":"10.1016/j.ihj.2025.02.005","DOIUrl":"10.1016/j.ihj.2025.02.005","url":null,"abstract":"<div><h3>Background</h3><div>A widely accepted concept in cardiovascular physiology states that diastole constitutes 62.5 % of the cardiac cycle during a typical 0.8-s cycle at 75 beats per minute. However, this has not been confirmed by using modern technology in healthy individuals.</div></div><div><h3>Objective</h3><div>This study aimed to accurately measure diastolic duration as a fraction of the cardiac cycle using echocardiography in healthy adults with structurally normal hearts.</div></div><div><h3>Methods</h3><div>In this prospective study, 200 healthy adults aged over 18 years, with heart rates between 50 and 100 beats per minute, normal ECGs, and structurally normal hearts, were included. Using a modified apical 5-chamber view and pulse wave Doppler at the aortic and mitral valves, researchers measured the RR interval (total cardiac cycle), diastolic duration (from aortic valve closure to mitral valve closure), and systolic duration. Three measurements were taken for each parameter, and the mean was used for analysis.</div></div><div><h3>Results</h3><div>Participants had a mean age of 47.7 years (range 19–79), with an equal gender distribution. The mean RR interval was 799 ± 97 ms. The left ventricular (LV) diastolic duration was 469 ± 76 ms, and the LV systolic duration was 330 ± 42 ms. The ratio of diastolic duration to the total cardiac cycle was 0.58 ± 0.04, slightly higher in males (0.59 ± 0.04) compared to females (0.57 ± 0.04).</div></div><div><h3>Conclusion</h3><div>This study challenges the longstanding teaching that diastole accounts for two-thirds of the cardiac cycle. Instead, diastole represents 58 % of the cycle, highlighting the need to reconsider its role in cardiovascular physiology and clinical applications.</div></div>","PeriodicalId":13384,"journal":{"name":"Indian heart journal","volume":"77 2","pages":"Pages 73-77"},"PeriodicalIF":1.4,"publicationDate":"2025-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143472475","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Prevalence of periodontitis in chronic heart failure patients and its relationship with NT-ProBNP: A cross-sectional study","authors":"Sonika Sharma ,&nbsp;Deepti Mathur ,&nbsp;Sourabh Goswami ,&nbsp;Manoj Kumar Gupta ,&nbsp;Pankaj Bhardwaj ,&nbsp;Pravin Kumar ,&nbsp;Surender Deora","doi":"10.1016/j.ihj.2025.03.004","DOIUrl":"10.1016/j.ihj.2025.03.004","url":null,"abstract":"<div><h3>Background</h3><div>Periodontal disease has been associated with chronic heart failure (CHF) and may be an indicator of high risk of adverse cardiovascular outcomes. To date, only few studies have been done and none from India regarding the association of periodontal disease in heart failure patients. So, this study was done to assess the prevalence of periodontitis in CHF patients and its correlation with N-terminal pro brain natriuretic peptide (NT- ProBNP).</div></div><div><h3>Materials and method</h3><div>In this study, 154 patients with stable CHF with left ventricular ejection fraction of less than 40 % were enrolled. All subjects underwent cardiologic and dental evaluations. NT pro-BNP level was measured in all patients. The periodontal screening index was used to quantify the degree of periodontal disease.</div></div><div><h3>Results</h3><div>Gingivitis, moderate periodontitis, and severe periodontitis were present in 48 (31.2 %), 82 (53.2 %), and 24 (15.5 %) patients, respectively. In individuals under the age of 75 years, the study found a significant association between moderate and severe periodontitis and elevated NT-proBNP levels (<em>p</em> &lt; 0.05). The comparison between gingivitis and moderate/severe periodontitis was statistically significant in post hoc analysis.</div></div><div><h3>Conclusion</h3><div>CHF patients exhibit a high prevalence of moderate and severe periodontitis. This study highlights a significant association between periodontitis severity and elevated NT-proBNP in CHF patients, underscoring a potential cardiac impact. Further research is warranted to deepen our understanding of this relationship.</div></div>","PeriodicalId":13384,"journal":{"name":"Indian heart journal","volume":"77 2","pages":"Pages 110-113"},"PeriodicalIF":1.4,"publicationDate":"2025-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143585578","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}