Indian heart journal最新文献

{"title":"Distributive shock in cardiac intensive care unit patients.","authors":"Sarvesh Pal Singh","doi":"10.1016/j.ihj.2025.09.008","DOIUrl":"10.1016/j.ihj.2025.09.008","url":null,"abstract":"<p><p>Shock is a life-threatening condition of circulatory failure. Mixed shock is observed in approximately 24.5 % of patients with cardiogenic shock. In cases of out-of-hospital cardiac arrest, outcomes are worse when the predominant shock type is distributive rather than cardiogenic. Thus, distinguishing between cardiogenic and distributive phenotypes is crucial for appropriate management. A dysregulated immune response has been observed in both. This review article details the pathophysiology, diagnostic challenges, and management of distributive shock when encountered in a cardiac intensive care unit.</p>","PeriodicalId":13384,"journal":{"name":"Indian heart journal","volume":" ","pages":""},"PeriodicalIF":1.8,"publicationDate":"2025-09-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145212524","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Contemporary Management of Calcified Coronary Artery Disease.","authors":"Nagendra Boopathy Senguttavan, Venkatakrishnan Ramakumar, Nitish Naik, Annapoorna Kini, Samin K Sharma","doi":"10.1016/j.ihj.2025.09.007","DOIUrl":"https://doi.org/10.1016/j.ihj.2025.09.007","url":null,"abstract":"","PeriodicalId":13384,"journal":{"name":"Indian heart journal","volume":" ","pages":""},"PeriodicalIF":1.8,"publicationDate":"2025-09-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145206325","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Intravascular imaging-guided drug-coated balloon treatment for coronary artery disease:Evidence and practice.","authors":"Atit A Gawalkar, Gary S Mintz, Nitish Naik","doi":"10.1016/j.ihj.2025.09.006","DOIUrl":"10.1016/j.ihj.2025.09.006","url":null,"abstract":"","PeriodicalId":13384,"journal":{"name":"Indian heart journal","volume":" ","pages":""},"PeriodicalIF":1.8,"publicationDate":"2025-09-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145191681","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Infectious agents, protein electrophoresis and immunoglobulin levels in patients with coronary artery ectasia.","authors":"Gulay Yetkin, Didem Tascioglu, Selcuk Ozturk, Bilal Cuglan, Kenan Yalta, Ertan Yetkin","doi":"10.1016/j.ihj.2025.09.004","DOIUrl":"10.1016/j.ihj.2025.09.004","url":null,"abstract":"<p><strong>Background: </strong>Although the mechanism of coronary artery ectasia (CAE) shares the common pathophysiologic steps resembling those of atherosclerosis, there are certain discrepancies or aspects incompatible with atherosclerosis. Therefore, we hypothesize that the pathophysiology of CAE might differ from that of atherosclerosis in terms of inflammatory parameters, infectious agents and the read out of protein electrophoresis.</p><p><strong>Materials and methods: </strong>Seventy patients with coronary artery disease (CAD) and 30 patients with both CAD and CAE comprised the study populations. Blood samples were centrifuged for the measurement of IgG antibodies against C.pneumoniae and H.Pylori, alongside with total IgE, IgG levels and protein electrophoresis.</p><p><strong>Results: </strong>There were not statistically significant differences between patients with and without CAE regarding the complete blood counting and routine biochemical laboratory parameters except hemoglobin levels. Among other studied laboratory parameters, IgE, Alpha 2 macroglobulin, Beta-1 globulin levels were found to be higher in patients with CAE + CAD than those of CAD alone. Logistic regression analysis by including the variables IgE, Hb, Alpha 2 macroglobulin, beta-1 globulin, and gender, revealed that Ig E (Odd ratio:1.004 85 % CI: 1.000-1.008, p = 0.01) and alpha 2 macroglobulin (Odds ratio: 9.41, 95 %CI: 1.69-52.28, p = 0.028) were independently and positively associated with the presence of CAE.</p><p><strong>Conclusion: </strong>Independent association of serum IgE levels and alpha2 globulins with the presence of CAE underlines the divergent features of pathophysiology of CAE compared with atherosclerosis or CAD alone. Comparable activity of humoral immunity measured by IgG antibody against C.Pneumoniae, and H. Pylori has suggested that these infectious agents do not play an additional role in the pathogenesis of CAE.</p>","PeriodicalId":13384,"journal":{"name":"Indian heart journal","volume":" ","pages":""},"PeriodicalIF":1.8,"publicationDate":"2025-09-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145185795","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Institutional experience with ductus arteriosus stenting in neonates with duct dependent pulmonary circulation: Procedural outcomes & mid-term follow up.","authors":"Bhavik Champaneri, Abhay Pota, Tarun Parmar, Jigar Surti, Shilpa Deodhar, Amit Kungwani, Suresh Bishnoi, Amit Mishra, Trushar Gajjar, Shyam S Kothari","doi":"10.1016/j.ihj.2025.09.002","DOIUrl":"10.1016/j.ihj.2025.09.002","url":null,"abstract":"<p><strong>Objective: </strong>Ductal stenting (DS) has emerged as a critical intervention for neonates with duct-dependent pulmonary circulation (DDPC), offering a less invasive alternative to surgical shunts.</p><p><strong>Methods: </strong>This retrospective study evaluates the procedural and mid-term outcomes of neonatal DS at a high-volume tertiary cardiac centre between January 2018 and August 2023.</p><p><strong>Results: </strong>The study involved 124 symptomatic neonates. Primary outcomes included procedural success, defined as achieving post-procedural oxygen saturation (SpO2) ≥85 %, and survival to planned surgical repair. Secondary outcomes assessed included unplanned re-interventions, pulmonary artery growth, and all-cause mortality within 6 months. Success rate was 98.5 %. Total hospital stay was 3.17 ± 4 days. All-cause mortality was 8.9 %. Branch PA origin stenosis was found in 42 % cases on follow up.</p><p><strong>Conclusion: </strong>The study concludes that DS is a feasible and effective strategy in a variety of different cases of DDPC. Further research is needed to explore long-term outcomes and optimal stent selection based on individual patient characteristics.</p>","PeriodicalId":13384,"journal":{"name":"Indian heart journal","volume":" ","pages":""},"PeriodicalIF":1.8,"publicationDate":"2025-09-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145174798","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Prediction of incident heart failure and/or re-hospitalization using different risk predictor models in Indian patients.","authors":"Anupam Kumar, Aditya Kapoor, S Harikrishnan, Arpita Katheria, Harshit Khare, Arshad Nazir, Ankit Kumar Sahu, Roopali Khanna, Sudeep Kumar, Naveen Garg, Satyendra Tewari","doi":"10.1016/j.ihj.2025.09.005","DOIUrl":"10.1016/j.ihj.2025.09.005","url":null,"abstract":"<p><strong>Background and aims: </strong>Accurate prediction of incident heart failure (HF), risk of recurrent HF or hospitalization are essential for optimizing patient outcomes. Seeing the rising trends of HF in Indians, the present study assessed the applicability of 5 different HF risk scores in these patients.</p><p><strong>Methods and results: </strong>Of the 280 patients recruited, 159 (55.7 %) had HF Stage A, B while 121 (44.3 %) had asymptomatic or symptomatic HF (HF Stage C, D). At 30 ± 7.5 months, new onset HF occurred in 32.07 % and in Stage C/D HF patients, rehospitalization was noted in 37.1 % and 8.9 % died. The incidence of new-onset HF increased incrementally with higher Health ABC scores (13.7, 31.4 and 52.9 % in score 5-10 %, 10-20 %, >20 % respectively). Amongst diabetic patients, TRS-HFDM score strongly predicted new-onset HF (16.7, 30 and 43.3 % in score 1,2 and ≥ 3 respectively). LACE index also accurately predicted events in those with Stage C/D HF: rehospitalization for recurrent HF was 6.6, 44.5 and 48.9 % while mortality was 4, 36 and 60 % in those with LACE index 0-4, 5-9, >9 respectively. Patients without any events had a lower MAGGIC score (19.25 ± 9.56) vs those who died (29.33 ± 8.32). H2FPEF score also performed well: re-hospitalization for HF was 22.2 vs 57.7 % and mortality was 20 vs 72 % in score <2 vs score >2.</p><p><strong>Conclusion: </strong>These easily available risk scores can accurately predict events in Indian patients with HF and should be part of clinical workflow.</p>","PeriodicalId":13384,"journal":{"name":"Indian heart journal","volume":" ","pages":""},"PeriodicalIF":1.8,"publicationDate":"2025-09-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145174901","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Presence of myocardial fibrosis on cardiac MRI and its impact on short-term outcomes in an Asian cohort of heart failure with preserved ejection fraction (HFpEF).","authors":"Sudipta Mondal, Swasthi S Kumar, Garikapati Vrandha, Ajit Kumar Valaparambil Kumaran, Bijulal Sasidharan, Harikrishnan Sivadasanpillai, Anoop Ayappan, Jayakrishnan Radhakrishnan, Suprakash Mandal","doi":"10.1016/j.ihj.2025.09.003","DOIUrl":"10.1016/j.ihj.2025.09.003","url":null,"abstract":"<p><strong>Backgrounds and objectives: </strong>This study aims to evaluate the presence and prognostic significance of myocardial fibrosis in subjects with and without HFpEF, using Cardiac MRI.</p><p><strong>Methods: </strong>This was an ambidirectional observational study [mean follow-up: 25 months], selecting HFpEF patients and comparing them with an age and sex-matched control arm without HF. Late gadolinium-enhanced (LGE) imaging and T1 mapping were used to assess fibrosis.</p><p><strong>Results: </strong>LGE (27 % vs 0 %, p = 0.005) and mid-segment (1062 ± 64 ms vs 1020±8 ms, p < 0.001) or total average (1057 ± 70 ms vs 1020±4 ms, p = 0.006) T1 values were significantly higher in HFpEF group (N = 30) compared to the control group. However, there was no significant difference in T2 values (p = 0.657). 53.3 % of our patients with HFpEF had a clinical event (HF hospitalization, stroke or all-cause mortality) during the follow-up. It was found that average mid-segment (1099 ± 67 ms vs 1019 ± 17 ms, p<0.001) and total average (1101 ± 70 ms vs 1007 ± 15 ms, p<0.001) T1 values were significantly higher in the event group compared to the no-event group. There were no differences in LGE prevalence between event and no-event groups. However, LGE negative cases had significantly increased T1 values in all segments compared to the healthy control group (p<0.001).</p><p><strong>Conclusions: </strong>Higher T1 values but not T2 values , were associated with the HFpEF group compared to the age and sex-matched control group. Focal fibrosis, as evident by LGE, was significantly more in HFpEF. Among HFpEF patients, high T1 myocardial values were associated with a higher rate of all-cause death, stroke, and HF hospitalization in short-term follow-up.</p>","PeriodicalId":13384,"journal":{"name":"Indian heart journal","volume":" ","pages":""},"PeriodicalIF":1.8,"publicationDate":"2025-09-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145148787","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Research limitations and future directions in assessing cardiology fellow competency in India.","authors":"Kunal Mahajan, Jaibharat Sharma, Surender Himral","doi":"10.1016/j.ihj.2025.09.001","DOIUrl":"10.1016/j.ihj.2025.09.001","url":null,"abstract":"","PeriodicalId":13384,"journal":{"name":"Indian heart journal","volume":" ","pages":""},"PeriodicalIF":1.8,"publicationDate":"2025-09-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145069491","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Floating wire assisted device retrieval-a novel technique for prevention of guide-related coronary injury.","authors":"Atit A Gawalkar, Rajesh Vijayvergiya, Pragya Karki","doi":"10.1016/j.ihj.2025.08.005","DOIUrl":"10.1016/j.ihj.2025.08.005","url":null,"abstract":"<p><strong>Background: </strong>An inward force is experienced by the guide catheter during device retrieval resulting in potential risk of deep engagement into the ostio-proximal coronary segment. This undesired movement can result in coronary injury. There is no systematic data or reports of techniques to prevent such inadvertent guide movement during difficult retrieval of devices.</p><p><strong>Methods: </strong>In 25 patients undergoing percutaneous coronary intervention, where the conventional methods of guide stabilization failed to prevent deep engagement of guide catheter during device retrieval we used 'floating aortic wire' technique and reattempted retrieval. The primary endpoint was the successful retrieval of the device without deep engagement of the guide.</p><p><strong>Results: </strong>Successful retrieval was seen without deep engagement of guide in 23(92 %) patients. Left anterior descending(n = 15, 60 %) artery was the most common coronary artery. The XB guide(n = 14, 70 %) was the most commonly used guide for left coronary intervention while Judgkins right and Amplatz left were used most commonly for right coronary intervention. Stent balloon(n = 15, 60 %) was the most common device which required using floating aortic wire for retrieval. Other devices were jailed wire(n = 5,20 %), non-compliant balloon(n = 4,16 %) and cutting balloon(n = 1,4 %). Intravascular ultrasound did not show any guide related vessel injury(dissection or intramural hematoma) in any cases. The floating aortic wire failed to prevent deep engagement in two patients because of longer segment of jailed wire and long stent balloon in distal right coronary artery.</p><p><strong>Conclusion: </strong>Floating aortic wire assisted retrieval of coronary devices is a simple, reliable and safe technique that prevents deep guide engagement during difficult retrieval.</p>","PeriodicalId":13384,"journal":{"name":"Indian heart journal","volume":" ","pages":""},"PeriodicalIF":1.8,"publicationDate":"2025-09-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145008233","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Preventing atrial fibrillation recurrence with combination of catheter ablation and renal denervation or ganglion plexus ablation: A systematic review and network meta-analysis.","authors":"Sebastian Emmanuel Willyanto, Liliana Dewi, Rizki Hari Mulia, Imke Maria Del Rosario Puling, Nyoman Deva Pramana Giri, Derren David Christian Homenta Rampengan, Ardian Rizal","doi":"10.1016/j.ihj.2025.08.004","DOIUrl":"10.1016/j.ihj.2025.08.004","url":null,"abstract":"<p><strong>Background: </strong>Atrial fibrillation (AF), affects around 2 % of the global population and is projected to rise over the next 50 years. Catheter ablation (CA) is the primary treatment for symptomatic AF resistant to drug therapy. Despite its widespread use, CA has a failure rate of 20 %-50 %, often requiring repeat procedures, due to significant long-term recurrence rates. Combining CA with renal denervation (RDN) or ganglion plexus ablation (GPA) may effectively reduce the recurrence rates of AF.</p><p><strong>Methods: </strong>Quality assessment was done using the Cochrane ROB 2.0 tool, network meta-analysis using RStudio, and comparative meta-analysis using RevMan 5.4.</p><p><strong>Results: </strong>A thorough search across seven databases resulted in 13 articles for analysis, with eight classified as low-risk and five as moderate-risk of bias. The network meta-analysis found that RDN + CA had the highest freedom from AF episodes at 12 and 24 months (OR 2.28 [1.34-3.86] and OR 1.61 [0.89-2.89]), followed by GPA + CA (OR 1.88 [0.91-3.89] and OR 1.36 [0.91-2.03]), compared to CA alone. RDN + CA also showed fewer procedure-related complications (OR 0.78 [0.30-2.02]), while GPA + CA was more prevalent (OR 3.60 [1.72-7.55]), compared to CA alone. Additionally, RDN + CA significantly reduced systolic blood pressure (SBP) (MD -5.22 [-9.91 to -0.53]), diastolic blood pressure (DBP) (MD -3.61 [-7.98 to -0.76]), and creatinine levels (MD -0.25 [-0.34 to -0.15]), while increasing estimated glomerular filtration rate (eGFR) (MD 7.98 [-1.16-17.11]) compared to the control group.</p><p><strong>Conclusion: </strong>Remarkable success in preventing AF recurrence was observed when CA was combined with RDN or GPA. However, it is noteworthy that GPA + CA was associated with a higher incidence of procedural-related complications, while RDN + CA demonstrated additional advantages by improving blood pressure regulation and renal function.</p>","PeriodicalId":13384,"journal":{"name":"Indian heart journal","volume":" ","pages":""},"PeriodicalIF":1.8,"publicationDate":"2025-09-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145006055","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}