Prevalence of periodontitis in chronic heart failure patients and its relationship with NT-ProBNP: A cross-sectional study

IF 1.4 Q3 CARDIAC & CARDIOVASCULAR SYSTEMS

Indian heart journal Pub Date : 2025-03-01 DOI:10.1016/j.ihj.2025.03.004

Sonika Sharma , Deepti Mathur , Sourabh Goswami , Manoj Kumar Gupta , Pankaj Bhardwaj , Pravin Kumar , Surender Deora

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引用次数: 0

Abstract

Background

Periodontal disease has been associated with chronic heart failure (CHF) and may be an indicator of high risk of adverse cardiovascular outcomes. To date, only few studies have been done and none from India regarding the association of periodontal disease in heart failure patients. So, this study was done to assess the prevalence of periodontitis in CHF patients and its correlation with N-terminal pro brain natriuretic peptide (NT- ProBNP).

Materials and method

In this study, 154 patients with stable CHF with left ventricular ejection fraction of less than 40 % were enrolled. All subjects underwent cardiologic and dental evaluations. NT pro-BNP level was measured in all patients. The periodontal screening index was used to quantify the degree of periodontal disease.

Results

Gingivitis, moderate periodontitis, and severe periodontitis were present in 48 (31.2 %), 82 (53.2 %), and 24 (15.5 %) patients, respectively. In individuals under the age of 75 years, the study found a significant association between moderate and severe periodontitis and elevated NT-proBNP levels (p < 0.05). The comparison between gingivitis and moderate/severe periodontitis was statistically significant in post hoc analysis.

Conclusion

CHF patients exhibit a high prevalence of moderate and severe periodontitis. This study highlights a significant association between periodontitis severity and elevated NT-proBNP in CHF patients, underscoring a potential cardiac impact. Further research is warranted to deepen our understanding of this relationship.

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慢性心力衰竭患者牙周炎患病率及其与NT-ProBNP的关系：一项横断面研究

背景：牙周病与慢性心力衰竭（CHF）有关，可能是心血管不良结局高风险的一个指标。迄今为止，只有很少的研究已经完成，而且没有来自印度关于牙周病与心力衰竭患者的关系。因此，本研究旨在评估CHF患者牙周炎的患病率及其与n端脑利钠肽前体（NT- ProBNP）的相关性。材料和方法：本研究纳入了154例左室射血分数小于40%的稳定型CHF患者。所有受试者都进行了心脏和牙科检查。所有患者均检测NT - pro-BNP水平。牙周筛查指数用于量化牙周病的程度。结果：牙龈炎48例（31.2%），中度牙周炎82例（53.2%），重度牙周炎24例（15.5%）。在75岁以下的个体中，研究发现中度和重度牙周炎与NT-proBNP水平升高之间存在显著关联(结论：CHF患者表现出中度和重度牙周炎的高患病率。这项研究强调了心力衰竭患者牙周炎严重程度与NT-proBNP升高之间的显著关联，强调了潜在的心脏影响。为了加深我们对这种关系的理解，有必要进行进一步的研究。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Indian heart journal CARDIAC & CARDIOVASCULAR SYSTEMS-

CiteScore

2.60

自引率

6.70%

发文量

审稿时长

52 days

期刊介绍： Indian Heart Journal (IHJ) is the official peer-reviewed open access journal of Cardiological Society of India and accepts articles for publication from across the globe. The journal aims to promote high quality research and serve as a platform for dissemination of scientific information in cardiology with particular focus on South Asia. The journal aims to publish cutting edge research in the field of clinical as well as non-clinical cardiology - including cardiovascular medicine and surgery. Some of the topics covered are Heart Failure, Coronary Artery Disease, Hypertension, Interventional Cardiology, Cardiac Surgery, Valvular Heart Disease, Pulmonary Hypertension and Infective Endocarditis. IHJ open access invites original research articles, research briefs, perspective, case reports, case vignette, cardiovascular images, cardiovascular graphics, research letters, correspondence, reader forum, and interesting photographs, for publication. IHJ open access also publishes theme-based special issues and abstracts of papers presented at the annual conference of the Cardiological Society of India.