Indian heart journal最新文献

{"title":"Response to Letter to the Editor \"Relapse in patients with non-ischemic dilated cardiomyopathy and improved ejection fraction managed with medical therapy\".","authors":"Arghadip Bose, Ajay Bahl","doi":"10.1016/j.ihj.2026.07.004","DOIUrl":"10.1016/j.ihj.2026.07.004","url":null,"abstract":"","PeriodicalId":13384,"journal":{"name":"Indian heart journal","volume":" ","pages":""},"PeriodicalIF":2.0,"publicationDate":"2026-07-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148648390","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Comment on \"Relapse in patients with non-ischemic dilated cardiomyopathy and improved ejection fraction managed with medical therapy\".","authors":"Noor Un Nisa, Fnu Kinza, Muhammad Hamza","doi":"10.1016/j.ihj.2026.07.006","DOIUrl":"10.1016/j.ihj.2026.07.006","url":null,"abstract":"","PeriodicalId":13384,"journal":{"name":"Indian heart journal","volume":" ","pages":""},"PeriodicalIF":2.0,"publicationDate":"2026-07-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148630297","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Response to Letter to the Editor, \"Cardiovascular risk profile among industrial workers in North India: A cross-sectional study\".","authors":"Bishav Mohan, Akash Batta, Sarit Sharma","doi":"10.1016/j.ihj.2026.07.008","DOIUrl":"10.1016/j.ihj.2026.07.008","url":null,"abstract":"","PeriodicalId":13384,"journal":{"name":"Indian heart journal","volume":" ","pages":""},"PeriodicalIF":2.0,"publicationDate":"2026-07-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148630365","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Re: Cardiovascular risk profile among industrial workers in North India: A cross-sectional study.","authors":"Shweta Thusoo","doi":"10.1016/j.ihj.2026.07.007","DOIUrl":"10.1016/j.ihj.2026.07.007","url":null,"abstract":"<p><p>In this study, Mohan et al found that, of the 15,527 industrial workers in Ludhiana, North India, 22% had hypertension, of which 85% was undiagnosed and 11% had diabetes. Three methodological issues discussed in this commentary are worthy of consideration: firstly, the implications of the largely migrant male workforce for generalisability; secondly, the lack of a structured cardiovascular risk-scoring system to put individual risk factor prevalence into context; and, thirdly, the need to consider occupational exposures (such as noise, shift work and heat stress) as separate cardiovascular risk factors not included in the study's risk profile.</p>","PeriodicalId":13384,"journal":{"name":"Indian heart journal","volume":" ","pages":""},"PeriodicalIF":2.0,"publicationDate":"2026-07-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148630376","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Two-wire technique for non aorto-ostial ostial stenting.","authors":"Pravin K Goel, Ankit Kumar Sahu","doi":"10.1016/j.ihj.2026.07.005","DOIUrl":"10.1016/j.ihj.2026.07.005","url":null,"abstract":"<p><p>Ostial stent placement invariably results in a 'miss' or 'overshoot' compromising clinico-angiographic outcomes and is largely due to the inadequate localization of the true ostium in different angiographic views. We herein describe a novel \"Two - wire technique\" for ostial stenting which helps precise ostial stent placement.</p>","PeriodicalId":13384,"journal":{"name":"Indian heart journal","volume":" ","pages":""},"PeriodicalIF":2.0,"publicationDate":"2026-07-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148602488","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Amiodarone-associated thyroid dysfunction: Current evidence and a practical approach to management.","authors":"Sharath Nagesh, Swathi Maiya, Ramya Das Nageri Kunnath","doi":"10.1016/j.ihj.2026.07.010","DOIUrl":"10.1016/j.ihj.2026.07.010","url":null,"abstract":"<p><strong>Background: </strong>Amiodarone is an effective antiarrhythmic agent but causes thyroid dysfunction in 15-20% of patients, resulting in amiodarone-induced hypothyroidism (AIH) and thyrotoxicosis (AIT).</p><p><strong>Methods: </strong>We performed a narrative review of randomized trials, prospective cohort studies, systematic reviews, and major guideline documents. PubMed and Embase were searched from January 2000 to December 2024 using terms related to amiodarone, thyroid dysfunction, thyrotoxicosis, and hypothyroidism. Priority was given to higher-quality evidence and contemporary society guidelines, including those from the ACC/AHA, ESC, ETA, and ATA.</p><p><strong>Results: </strong>AIH is generally managed with levothyroxine without routine amiodarone discontinuation. AIT requires phenotypic differentiation and phenotype-directed therapy, with corticosteroids preferred for Type 2 AIT and antithyroid drugs for Type 1 AIT. Decisions regarding amiodarone continuation should be individualized according to thyroid and cardiac risk.</p><p><strong>Conclusions: </strong>Baseline screening, structured monitoring, and phenotype-directed management allow effective treatment of amiodarone-associated thyroid dysfunction while preserving arrhythmia control.</p>","PeriodicalId":13384,"journal":{"name":"Indian heart journal","volume":" ","pages":""},"PeriodicalIF":2.0,"publicationDate":"2026-07-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148602490","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Quality of anticoagulation in self versus standard management: Assessing the influence of education level on self-managed patient outcomes.","authors":"Hossameldin Hussein, Amr Yosry Emam, Karimeldeen Hafez, Sara Abdelmordy Abdelmagid Ragab, Maha Abdallah, Eman Mahmoud Ramadan, Asmaa Abdelnaby, Mahmoud Abdelhay, Ahmed Hassan, Mohammed Hosny","doi":"10.1016/j.ihj.2026.07.003","DOIUrl":"10.1016/j.ihj.2026.07.003","url":null,"abstract":"<p><strong>Background: </strong>Self-management of vitamin K antagonist (VKA) therapy may enhance the quality of anticoagulation compared with conventional monitoring; however, selection criteria in low-socioeconomic settings-and the role of education-remain unclear. This study aims to evaluate the effect of education level and socio-economic factors on the quality of anticoagulation control.</p><p><strong>Methods: </strong>This single-center observational study included adult patients on VKA for ≥6 months; exclusions were age >70 years, prior life-threatening bleeding/thromboembolism, illiteracy without a co-resident caregiver, or refusal to join the study. Participants followed self-management (1-h training and a dose-INR algorithm with escalation rules) or standard clinic monitoring led by specialized nurses. Follow-up was conducted for 6 months. Primary endpoints were Roosendaal TTR and percentage of INR tests in range.</p><p><strong>Results: </strong>A total of 589 participants were enrolled (self-management n = 295; standard n = 294); 6-month TTR was available for 524 patients (255 vs 269; respectively). Median [Q1-Q3] TTR was similar between groups (63% [41-85] vs 59% [44-79]; p = 0.55), as was the percentage of INR tests in range (57% [36-78] vs 57% [42-71]; p = 0.76). Using tests-in-range categories, self-management had higher rates of both adequate control (>70%) (36.6% vs 27.1%; p = 0.024) and poor control (<30%) (18.1% vs 10.8%; p = 0.018). Within the self-management group, Rosendaal TTR did not differ by education level (70.2%, 62.4%, 65.2%, and 58.3% for illiterate/primary/secondary/higher education; p = 0.66).</p><p><strong>Conclusion: </strong>Self-management of INR is feasible in low-socioeconomic settings and is not predicted by education level; rather, it requires structured training, demonstrated competency, and an effective health-support system.</p>","PeriodicalId":13384,"journal":{"name":"Indian heart journal","volume":" ","pages":""},"PeriodicalIF":2.0,"publicationDate":"2026-07-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148578614","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Diagnostic value of fetal echocardiography in detecting congenital heart disease.","authors":"Michelle Viegas, Guruprasad D Naik, Sapna Narvekar, Rajvi D Lotliker, Lerin George","doi":"10.1016/j.ihj.2026.07.001","DOIUrl":"10.1016/j.ihj.2026.07.001","url":null,"abstract":"<p><strong>Objectives: </strong>To determine the sensitivity and specificity of fetal echo (FE) and predictive risk factors for congenital heart disease (CHD) in high-risk pregnancies.</p><p><strong>Methods: </strong>970 consecutive high-risk pregnancies referred for FE were studied. All patients were followed up with a neonatal echo. Risk factors in the mother were correlated with CHD in the fetus. The sensitivity and specificity of fetal echo for CHD were compared with the neonatal echo.</p><p><strong>Results: </strong>1010 fetuses were evaluated. A follow-up of the fetal echo was obtained in 904 (89.5%) patients. Risk factors for referral for fetal echocardiography included maternal diabetes (n = 454, 45%), echogenic foci (n = 93, 9.2%), cardiac anomaly on ultrasound (n = 90, 8.9%), and IVF pregnancies (n = 52, 5.1%). 0.4% had arrhythmias. 89 patients had CHD. VSD was the commonest CHD (15 patients), followed by single ventricle (11) and TOF (10). GDM did not correlate with CHD. None of the IVF pregnancies had CHD. Only ultrasound showing cardiac anomaly correlated with CHD (p < 0.001), but 25% of cases were missed. Fetal echo had a very high sensitivity of 95.5% and specificity of 99.5% for detecting CHD, with slightly reduced sensitivity of 94.3% after 28 weeks. The commonly missed anomalies were small VSDs and anomalies of venous drainage. The fetal mortality with CHD was significantly higher at 38.6% versus 4.5% with no CHD.</p><p><strong>Conclusion: </strong>Fetal echo has a very high sensitivity of 95.5% and specificity of 99.5% in detecting CHD. There was a high incidence of CHD in high-risk pregnancies, 88/1000. The most common CHD was VSD. Small VSDs and anomalies of venous drainage were the most frequently missed anomalies. In this study, GDM did not correlate with CHD. Ultrasound showing cardiac anomaly was the only predictor of CHD; hence, in India, where there is a shortage of healthcare resources, training radiologists to include outflow tract views and performing fetal echo in all high-risk pregnancies would result in optimal utilization of resources.</p>","PeriodicalId":13384,"journal":{"name":"Indian heart journal","volume":" ","pages":""},"PeriodicalIF":2.0,"publicationDate":"2026-07-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148561879","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Appropriate and inappropriate implantable cardioverter defibrillator therapy rates in a contemporary cohort.","authors":"Chandan Sharma, Aashish S Raman, Anish Bhargav, Ramanathan Velayutham, Raja Selvaraj","doi":"10.1016/j.ihj.2026.07.002","DOIUrl":"10.1016/j.ihj.2026.07.002","url":null,"abstract":"<p><strong>Background: </strong>Implantable cardioverter-defibrillators (ICDs) are effective in preventing sudden cardiac death; however, contemporary data regarding appropriate and inappropriate device therapy rates from India remains limited.</p><p><strong>Objective: </strong>To evaluate rate of appropriate and inappropriate ICD therapies in a cohort of patients who underwent ICD or CRT-D implantation for either primary or secondary prevention at a tertiary care centre METHODS: We conducted a retrospective single-centre study of 190 patients who underwent ICD or CRT-D implantation between 2010 and 2024 for primary or secondary prevention. The primary outcome included appropriate and inappropriate ICD therapy rates assessed using Kaplan-Meier analysis RESULTS: The mean age of cohort was 53.1 ± 12.5 years. Secondary prevention accounted for 79% of implants. Over mean follow-up of 43.4 ± 39.6 months, appropriate ICD therapy occurred in 23.2% of patients, with median time to first therapy of 28.5 months. The cumulative incidence of appropriate therapy was 6% at 1 year and 22% at 3 years. Inappropriate therapy occurred in 8.9% of patients with cumulative incidence of 4% and 8% at 1 and 3 years respectively. The rates of appropriate and inappropriate therapies were not statistically different between primary and secondary prevention groups (p = 0.92 and 0.72 respectively) and between ischemic and non-ischemic subset (p = 0.56 and 0.32 respectively).</p><p><strong>Conclusion: </strong>In this contemporary Indian cohort, ICD therapies remain substantial despite advances in GDMT, with a persistent long-term risk of ventricular arrhythmias. These findings support continued guideline-based ICD use and highlight the need to improve ICD utilization, particularly for primary prevention.</p>","PeriodicalId":13384,"journal":{"name":"Indian heart journal","volume":" ","pages":""},"PeriodicalIF":2.0,"publicationDate":"2026-07-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148561905","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Prevalence and predictors of aspirin and clopidogrel resistance by light transmittance platelet aggregometry in stable coronary artery disease","authors":"Nirmal Ghati,&nbsp;Rajiv Narang,&nbsp;Hara Prasad Pati,&nbsp;Ashwani Kumar Mishra,&nbsp;Aseem Basha","doi":"10.1016/j.ihj.2026.03.001","DOIUrl":"10.1016/j.ihj.2026.03.001","url":null,"abstract":"<div><h3>Objective</h3><div>The effect of aspirin and clopidogrel is not uniform in all patients due to drug resistance. The study was designed to evaluate the prevalence of aspirin and clopidogrel resistance and its association with various risk factors in stable CAD patients.</div></div><div><h3>Methods</h3><div>Total 151 clinically stable CAD patients taking either aspirin and/or clopidogrel were recruited in this prospective cohort study. Platelet function testing was performed using light transmittance platelet aggregometry. All the patients were prospectively followed up to detect any MACE (death, non-fatal MI, stroke, revascularization), worsening angina and bleeding from any site.</div></div><div><h3>Results</h3><div>Total 11 (7.28%) patients showed complete resistance to aspirin, and an additional 35 (23.18%) patients showed semi-resistance. For clopidogrel, 44 (29.2%) and 11 (7.6%) patients had complete and semi-resistance, respectively. The prevalence of dual antiplatelet resistance was 7.6%. In univariate regression analysis, diabetes mellitus [OR 2.2 (95%CI 1.1-4.4); <em>p</em>=0.03] and clopidogrel resistance [OR 20.2 (8-50.7); <em>p</em>&lt;0.01] showed significant association with aspirin resistance. The parameters significantly associated with clopidogrel resistance were – hemoglobin level [OR 0.8 (0.7-1); <em>p</em>=0.03], erythrocyte sedimentation rate [OR 1 (1-1.1); <em>p</em>=0.04], family history of CAD [OR 5.1 (1.5-17.1); <em>p</em>=0.01] and aspirin resistance [OR 20.2 (8.0-50.7); <em>p</em>&lt;0.01]. In multivariable analysis, apart from the significant association between aspirin and clopidogrel resistance, family history of CAD was the only independent predictor of clopidogrel resistance. The study was underpowered to detect any meaningful effect on MACE due to low event rate.</div></div><div><h3>Conclusion</h3><div>In our study high prevalence of aspirin and clopidogrel resistance was detected. Although aspirin and clopidogrel resistance showed significant association with clinical risk factors, their association with MACE was inconclusive.</div></div>","PeriodicalId":13384,"journal":{"name":"Indian heart journal","volume":"78 4","pages":"Pages 179-186"},"PeriodicalIF":2.0,"publicationDate":"2026-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147377400","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}