Indian Journal of Nephrology最新文献

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A Rare Case of Peritonitis in a Patient on CAPD for Nine Years 一例罕见的腹膜炎病例,患者使用 CAPD 长达九年之久
IF 0.8
Indian Journal of Nephrology Pub Date : 2024-06-10 DOI: 10.25259/ijn_64_2024
Arjun Parthasarathy, M. Mathew, Divya Sundar, Georgi Abraham
{"title":"A Rare Case of Peritonitis in a Patient on CAPD for Nine Years","authors":"Arjun Parthasarathy, M. Mathew, Divya Sundar, Georgi Abraham","doi":"10.25259/ijn_64_2024","DOIUrl":"https://doi.org/10.25259/ijn_64_2024","url":null,"abstract":"We report a case of peritonitis due to multi-drug-resistant Escherichia coli in a patient with diabetic kidney disease on continuous ambulatory peritoneal dialysis for nine years. As the peritonitis did not resolve with conventional medical therapy, a contrast-enhanced CT was done, which showed superior mesenteric artery thrombosis with bowel ischemia. The peritoneal dialysis catheter was removed, and appropriate antibiotics were continued as per International Society for Peritoneal Dialysis guidelines. A year later, the patient while on maintenance hemodialysis presented with obstructive jaundice due to a growth in the ampulla of vater.","PeriodicalId":13359,"journal":{"name":"Indian Journal of Nephrology","volume":null,"pages":null},"PeriodicalIF":0.8,"publicationDate":"2024-06-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141366203","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Bones, Stones, and Hematuria….Connecting the Dots 骨骼、结石和血尿.... 连接点
IF 0.8
Indian Journal of Nephrology Pub Date : 2024-06-10 DOI: 10.25259/ijn_531_23
Madhura P. Fadnis, Vijay Kalrao, Suprita Kalra, Suchi Acharya
{"title":"Bones, Stones, and Hematuria….Connecting the Dots","authors":"Madhura P. Fadnis, Vijay Kalrao, Suprita Kalra, Suchi Acharya","doi":"10.25259/ijn_531_23","DOIUrl":"https://doi.org/10.25259/ijn_531_23","url":null,"abstract":"We report a 12 yr old boy who presented with recurrent gross hematuria, polyuria and rickets with growth failure. Investigations showed bilateral renal calculi with small kidneys on ultrasonography along with hypercalciuria; hypomagnesemia and reduced kidney function. His younger sibling also had nephrocalcinosis hypomagnesemia. The genetic analysis done in view of recurrent renal calculi with chronic kidney disease showed a homozygous missense variant (c.392G>A) at exon 4 of CLDN 16 gene suggestive of Familial hypomagnesemia with hypercalciuria and nephrocalcinosis (FHHNC). The younger sibling had a similar homozygous mutation and the parents were heterozygous carriers.","PeriodicalId":13359,"journal":{"name":"Indian Journal of Nephrology","volume":null,"pages":null},"PeriodicalIF":0.8,"publicationDate":"2024-06-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141364107","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Post-Diarrheal Acute Kidney Injury During an Epidemic in Monsoon – A Retrospective Study from a Tertiary Care Hospital 季风流行期间腹泻后急性肾损伤--来自一家三级医院的回顾性研究
IF 0.8
Indian Journal of Nephrology Pub Date : 2024-06-10 DOI: 10.25259/ijn_285_23
Nived Haridas, S. Thirumavalavan, M. Fernando, Murugesan Vellaisamy, Poongodi Annadurai, N. Srinivasaprasad, Sujit Surendran, K. T. Valavan, Jerry Joseph, M.S. Gayathri
{"title":"Post-Diarrheal Acute Kidney Injury During an Epidemic in Monsoon – A Retrospective Study from a Tertiary Care Hospital","authors":"Nived Haridas, S. Thirumavalavan, M. Fernando, Murugesan Vellaisamy, Poongodi Annadurai, N. Srinivasaprasad, Sujit Surendran, K. T. Valavan, Jerry Joseph, M.S. Gayathri","doi":"10.25259/ijn_285_23","DOIUrl":"https://doi.org/10.25259/ijn_285_23","url":null,"abstract":"\u0000\u0000Acute kidney injury (AKI) is a severe complication of acute diarrheal diseases; however, there is limited data on post-diarrheal AKI (PD-AKI) epidemiology and outcomes. This study aimed to investigate the clinicodemographic profile and outcomes of PD-AKI in our hospital.\u0000\u0000\u0000\u0000We retrospectively analyzed data from 93 patients admitted with PD-AKI during a diarrheal illness epidemic. Patients were stratified based on the Kidney Disease: Improving Global Outcomes (KDIGO) AKI stage and quick Sequential Organ Failure Assessment (qSOFA) score. Clinicodemographic data and outcomes were recorded and analyzed.\u0000\u0000\u0000\u0000The mean age of the patients was 45.7 ± 11.9 years, with a majority being men (n = 55, 59%). All patients presented with watery diarrhea, 85% (n = 79) had vomiting, and 66% (n = 61) presented in shock. At presentation, 59% were oliguric, while 32% were anuric. KDIGO stage 3 AKI was observed in 71% (n = 66) of patients. Dialytic support was required in 29% (n = 27) of cases. The mortality rate was 6.5% (n = 6), mostly due to refractory shock, while the remaining patients recovered. Risk factor analysis demonstrated a higher qSOFA score, and peak serum creatinine levels were associated with an increased likelihood of requiring renal replacement therapy and delayed renal recovery.\u0000\u0000\u0000\u0000This study provides valuable insights into the clinicodemographic characteristics and outcomes of PD-AKI. The high prevalence of severe AKI emphasizes the importance of early recognition and appropriate management strategies for these patients.\u0000","PeriodicalId":13359,"journal":{"name":"Indian Journal of Nephrology","volume":null,"pages":null},"PeriodicalIF":0.8,"publicationDate":"2024-06-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141365375","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Hub and Spoke Model for Kidney Care – From Prevention to Treatment 肾脏护理的 "枢纽和辐条模式"--从预防到治疗
IF 0.8
Indian Journal of Nephrology Pub Date : 2024-06-10 DOI: 10.25259/ijn_165_2024
M. Sahay
{"title":"Hub and Spoke Model for Kidney Care – From Prevention to Treatment","authors":"M. Sahay","doi":"10.25259/ijn_165_2024","DOIUrl":"https://doi.org/10.25259/ijn_165_2024","url":null,"abstract":"","PeriodicalId":13359,"journal":{"name":"Indian Journal of Nephrology","volume":null,"pages":null},"PeriodicalIF":0.8,"publicationDate":"2024-06-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141366404","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Anti-Phospholipase A2 Receptor Antibody (Anti-PLA2R) Testing to the Rescue 抗磷脂酶 A2 受体抗体(Anti-PLA2R)检测的救星
IF 0.8
Indian Journal of Nephrology Pub Date : 2024-06-10 DOI: 10.25259/ijn_413_23
A.S. Nath, Siddharth Herur, G. Taduri, Swarnalatha Guditi, R. Kalidindi, Prasanna Murugan, Rahul R. Nair, Niranjan Ganesh
{"title":"Anti-Phospholipase A2 Receptor Antibody (Anti-PLA2R) Testing to the Rescue","authors":"A.S. Nath, Siddharth Herur, G. Taduri, Swarnalatha Guditi, R. Kalidindi, Prasanna Murugan, Rahul R. Nair, Niranjan Ganesh","doi":"10.25259/ijn_413_23","DOIUrl":"https://doi.org/10.25259/ijn_413_23","url":null,"abstract":"Serological testing for M-type anti-phospholipase A2 receptor antibodies (antiPLA2R Ab) has abrogated the need for kidney biopsy to diagnose membranous nephropathy in the appropriate clinical setting. We report a case of a 63-year-old hypertensive male who presented with nephrotic syndrome associated with autosomal dominant polycystic kidney disease which was effectively diagnosed with the use of antiPLA2R Ab test. He achieved complete remission upon treatment with Rituximab. Hitherto, all anecdotal case reports of this uncommon association were diagnosed only by kidney biopsy. We highlight the usefulness of PLA2RAb especially in such cases of difficult-to-biopsy kidneys.","PeriodicalId":13359,"journal":{"name":"Indian Journal of Nephrology","volume":null,"pages":null},"PeriodicalIF":0.8,"publicationDate":"2024-06-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141364040","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Strategies to Circumvent Discrepancies in Pre-Transplant Donor Specific Antibodies Workup 避免移植前捐献者特异性抗体检测中出现差异的策略
IF 0.8
Indian Journal of Nephrology Pub Date : 2024-06-10 DOI: 10.25259/ijn_60_2024
L. Rani, Ritu Aggarwal, Mahendra Kumar, Raja Ramachandran, Ashish Sharma, R. Minz
{"title":"Strategies to Circumvent Discrepancies in Pre-Transplant Donor Specific Antibodies Workup","authors":"L. Rani, Ritu Aggarwal, Mahendra Kumar, Raja Ramachandran, Ashish Sharma, R. Minz","doi":"10.25259/ijn_60_2024","DOIUrl":"https://doi.org/10.25259/ijn_60_2024","url":null,"abstract":"","PeriodicalId":13359,"journal":{"name":"Indian Journal of Nephrology","volume":null,"pages":null},"PeriodicalIF":0.8,"publicationDate":"2024-06-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141361448","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Acute Invasive Fungal Thyroiditis – A Catastrophic Event Post-Renal Transplant 急性侵袭性真菌性甲状腺炎--肾移植后的灾难性事件
IF 0.8
Indian Journal of Nephrology Pub Date : 2024-06-10 DOI: 10.25259/ijn_92_2024
Garima Rawat, H. Aiyer, Aditi Shukla, Sunil Dharmani
{"title":"Acute Invasive Fungal Thyroiditis – A Catastrophic Event Post-Renal Transplant","authors":"Garima Rawat, H. Aiyer, Aditi Shukla, Sunil Dharmani","doi":"10.25259/ijn_92_2024","DOIUrl":"https://doi.org/10.25259/ijn_92_2024","url":null,"abstract":"","PeriodicalId":13359,"journal":{"name":"Indian Journal of Nephrology","volume":null,"pages":null},"PeriodicalIF":0.8,"publicationDate":"2024-06-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141361880","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
A Case of Acute Renal Infarct Secondary to Protein S Deficiency 一个继发于蛋白 S 缺乏症的急性肾梗塞病例
IF 0.8
Indian Journal of Nephrology Pub Date : 2024-06-10 DOI: 10.25259/ijn_522_23
Daniel Sam Mathews, Ninoo George, Ranjith Jeyasekharan
{"title":"A Case of Acute Renal Infarct Secondary to Protein S Deficiency","authors":"Daniel Sam Mathews, Ninoo George, Ranjith Jeyasekharan","doi":"10.25259/ijn_522_23","DOIUrl":"https://doi.org/10.25259/ijn_522_23","url":null,"abstract":"Renal infarction is an underdiagnosed and underreported condition with multiple etiologies. A 45-year-old man presented with acute pain in the right lumbar region, CT scan showed a wedge shaped, non-enhancing, hypodense lesion in the cortex of the upper pole of the right kidney- suggestive of infarct. A pro-thrombotic workup revealed a protein S deficiency and a heterozygous mutation for MTHFR gene. Protein S is a vitamin-K dependent plasma glycoprotein, the deficiency of which is associated with a hypercoagulable state, which in turn led to renal infarction in this patient.","PeriodicalId":13359,"journal":{"name":"Indian Journal of Nephrology","volume":null,"pages":null},"PeriodicalIF":0.8,"publicationDate":"2024-06-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141365838","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Comparison of Different Equations with GFR Measured by Scintigraphy in Kidney Donors 不同公式与闪烁成像测量的肾脏捐献者 GFR 的比较
IF 0.8
Indian Journal of Nephrology Pub Date : 2024-06-04 DOI: 10.25259/ijn_417_23
Gerard Vinodh, P. Dheerendra, Aleya Anitha, D. Anandkumar, Deepesh Vellakampadi, Gokulnath
{"title":"Comparison of Different Equations with GFR Measured by Scintigraphy in Kidney Donors","authors":"Gerard Vinodh, P. Dheerendra, Aleya Anitha, D. Anandkumar, Deepesh Vellakampadi, Gokulnath","doi":"10.25259/ijn_417_23","DOIUrl":"https://doi.org/10.25259/ijn_417_23","url":null,"abstract":"\u0000\u0000Technetium-99m diethylene-triamine-pentaacetate (99mTc-DTPA)-based scintigraphy is a convenient way to assess measured glomerular filtration rate (mGFR) in kidney donors. Equations have been developed to calculate GFR in the general population. This study aims to identify the best among commonly employed equations to better predict GFR when compared with scintigraphy-based mGFR. Also, the trends in mGFR values were studied over 1 year post-donation.\u0000\u0000\u0000\u0000Thirty-four kidney donors were recruited for this study from November 2017 to November 2018 and followed-up for a year. Estimated GFR (eGFR) was calculated using the Modification of Diet in Renal Disease (MDRD) Equation, Chronic Kidney Disease Epidemiology (CKD-EPI) Collaboration equation, and Nankivell formula; the values were compared to that obtained using 99mTc-DTPA both pre-and post-donation. Correlation and agreement between the eGFR and mGFR were studied using Statistical Package for the Social Sciences (SPSS) version 23.0 and Microsoft Excel.\u0000\u0000\u0000\u0000mGFR was augmented by 32.3 ± 27.8% in the remnant kidney post-donation. The baseline mGFR, post-donation mGFR, and the quantum of its increase post-donation did not differ between overweight donors and donors with normal body mass index (BMI). mGFR correlated poorly with all the eGFR equations both pre- and post-donation. Bland-Altman analysis showed weak agreement with significant bias and variance between mGFR and all eGFR equations.\u0000\u0000\u0000\u0000In Indian kidney donors, mGFR by 99mTc-DTPA scintigraphy shows poor correlation and agreement with the commonly used eGFR equations. An individualized approach is needed to assess the kidney function of live donors to minimize harm to both the recipient and the donor.\u0000","PeriodicalId":13359,"journal":{"name":"Indian Journal of Nephrology","volume":null,"pages":null},"PeriodicalIF":0.8,"publicationDate":"2024-06-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141267075","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Membranous Nephropathy in a Treatment Naïve Patient of Rheumatoid Arthritis 类风湿关节炎新发患者的膜性肾病
IF 0.8
Indian Journal of Nephrology Pub Date : 2024-06-04 DOI: 10.25259/ijn_40_2024
Satish Kumar, Santosh Kumar Singh, Rahil Arora, A. Kashif
{"title":"Membranous Nephropathy in a Treatment Naïve Patient of Rheumatoid Arthritis","authors":"Satish Kumar, Santosh Kumar Singh, Rahil Arora, A. Kashif","doi":"10.25259/ijn_40_2024","DOIUrl":"https://doi.org/10.25259/ijn_40_2024","url":null,"abstract":"","PeriodicalId":13359,"journal":{"name":"Indian Journal of Nephrology","volume":null,"pages":null},"PeriodicalIF":0.8,"publicationDate":"2024-06-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141267308","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
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