Indian Journal of Nephrology最新文献

Nephrology's Next Frontier: Expanding the Reach of CAR T-Cell Therapy for Refractory Lupus Nephritis and Beyond. 肾病学的下一个前沿：扩大CAR - t细胞治疗难治性狼疮性肾炎及其他疾病的范围。

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Indian Journal of Nephrology Pub Date : 2025-07-01 Epub Date: 2024-12-11 DOI: 10.25259/IJN_274_2024

Jeyakumar Meyyappan, Narayan Prasad

引用次数: 0

Author's Reply. 作者的回答。

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Indian Journal of Nephrology Pub Date : 2025-07-01 Epub Date: 2025-02-25 DOI: 10.25259/IJN_782_2024

Shyam Bihari Bansal, Mayur Babras, Abhyuday Singh Rana, Sidharth Kumar Sethi

引用次数: 0

Artificial Intelligence in Nephrology: Pioneering Precision with Multimodal Intelligence. 肾脏学中的人工智能：用多模态智能开拓精度。

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Indian Journal of Nephrology Pub Date : 2025-07-01 Epub Date: 2025-05-08 DOI: 10.25259/IJN_496_2024

Pushkala Jayaraman, Ishita Vasudev, Akinchan Bhardwaj, Girish Nadkarni, Ankit Sakhuja, Priti Meena

{"title":"Artificial Intelligence in Nephrology: Pioneering Precision with Multimodal Intelligence.","authors":"Pushkala Jayaraman, Ishita Vasudev, Akinchan Bhardwaj, Girish Nadkarni, Ankit Sakhuja, Priti Meena","doi":"10.25259/IJN_496_2024","DOIUrl":"10.25259/IJN_496_2024","url":null,"abstract":"Artificial intelligence (AI) is a rapidly advancing tool in healthcare, which might have significant implications in nephrology. Integrating AI, particularly through models like GPT-3 and GPT-4, has potential in medical education and diagnostics, achieving accuracy in clinical assessments. AI's ability to analyze large, complex datasets from diverse modalities (electronic health records, imaging, and genetic data) might enable early detection, personalized treatment planning, and clinical decision-making. Key developments include AI-driven chronic kidney disease and acute kidney injury predictive models, which utilize machine learning algorithms to predict risk factors and disease onset, thereby allowing timely intervention. AI is enhancing non-invasive diagnostics like retinal imaging to detect kidney disease biomarkers, offering a promising and cost-effective approach to early disease detection. Despite these advancements, AI implementation in clinical practice faces challenges, including the need for robust data integration, model generalizability across diverse patient populations, and ethical and regulatory standards adherence. Maintaining transparency, explainability, and patient trust is crucial for AI's successful deployment in nephrology. This article explores AI's role in kidney care, covering its diagnostic applications, outcome prediction, and treatment, with references to recent studies that highlight its potential and current limitations.","PeriodicalId":13359,"journal":{"name":"Indian Journal of Nephrology","volume":"35 4","pages":"470-479"},"PeriodicalIF":0.8,"publicationDate":"2025-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12392215/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144952349","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

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Acute COVID-19 Vaccine-Associated Glomerulonephritis: An Effect of Vaccination or the Infection Itself? 急性COVID-19疫苗相关性肾小球肾炎：疫苗接种的作用还是感染本身？

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Indian Journal of Nephrology Pub Date : 2025-07-01 Epub Date: 2025-02-20 DOI: 10.25259/IJN_793_2024

Suprita Kalra

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Rituximab, Cyclophosphamide, and Corticosteroid Combination in Difficult-to-Treat Membranous Nephropathy. 利妥昔单抗、环磷酰胺和皮质类固醇联合治疗难治性膜性肾病。

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Indian Journal of Nephrology Pub Date : 2025-07-01 Epub Date: 2025-05-16 DOI: 10.25259/IJN_174_2025

Arun Prabhahar, Niranjan Anitha Vijayakumar, Joyita Bharati, Sushma Rani, Vinod Kumar, Ritambhra Nada, Smita Subhash Divyaveer, Manish Rathi, Harbir Singh Kohli, Vivekanand Jha, Raja Ramachandran

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Urinary Neutrophil Gelatinase Associated Lipocalin as a Marker of Nephropathy in Type 2 Diabetic Patients. 尿中性粒细胞明胶酶相关脂钙蛋白作为2型糖尿病患者肾病的标志物。

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Indian Journal of Nephrology Pub Date : 2025-07-01 Epub Date: 2025-03-11 DOI: 10.25259/IJN_787_2024

Olajumoke Ajele Ogundeji, Oyebola Oluwagbemiga Sonuga, Modupe Akinrele Kuti, Kombo Gayus Habila, Kehinde Sola Akinlade

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West Nile Virus Encephalitis in a Recent Kidney Transplant Recipient: An Unusual Presentation. 最近肾移植受者的西尼罗病毒脑炎：一种不寻常的表现。

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Indian Journal of Nephrology Pub Date : 2025-07-01 Epub Date: 2025-02-26 DOI: 10.25259/IJN_795_2024

Sumesh Sp Nair, Sajith Narayanan, N A Ismail, Sreejesh Balakrishnan

引用次数: 0

Approach to Diagnosis and Management of Pediatric Hypertension in an Outpatient Setting. 门诊儿科高血压的诊断和处理方法。

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Indian Journal of Nephrology Pub Date : 2025-07-01 Epub Date: 2025-05-21 DOI: 10.25259/IJN_385_2024

Shawn Khullar, Anu Asaithambi, Priya Pais, Rahul Chanchlani

{"title":"Approach to Diagnosis and Management of Pediatric Hypertension in an Outpatient Setting.","authors":"Shawn Khullar, Anu Asaithambi, Priya Pais, Rahul Chanchlani","doi":"10.25259/IJN_385_2024","DOIUrl":"10.25259/IJN_385_2024","url":null,"abstract":"Pediatric hypertension (HTN) is a public health concern with significant possible long-term adverse outcomes. This review is a comprehensive guide for pediatricians, nephrologists, and trainees, focusing on the latest approaches for HTN diagnoses in children and highlighting the importance of accurate blood pressure measurement techniques. We also explore current classification systems and offer evidence-based HTN management strategies tailored to pediatric patients. Lifestyle modifications are the recommended first-line interventions, including dietary changes, physical activity, and weight management. Pharmacological treatments are for severe cases or when lifestyle modifications are insufficient. The guidelines provide an overview of commonly prescribed antihypertensive medications, potential complications associated with untreated HTN, including target organ damage and increased cardiovascular risk in adulthood, and the importance of early recognition and intervention. This review aims to help healthcare professionals thoroughly understand pediatric HTN to improve diagnosis, treatment, and long-term outcomes.","PeriodicalId":13359,"journal":{"name":"Indian Journal of Nephrology","volume":"35 4","pages":"460-469"},"PeriodicalIF":0.8,"publicationDate":"2025-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12395093/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144952310","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Glomerulocystic Kidney Disease in an Adult with DNAH1 Mutation: A Case Report. 成人肾小球囊性肾病伴DNAH1突变1例报告

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Indian Journal of Nephrology Pub Date : 2025-07-01 Epub Date: 2024-06-29 DOI: 10.25259/IJN_130_2024

Abhilasha Soni, Manish Chaturvedy, Nitin Bajpai, Vikarn Vishwajeet, Rajesh Jhorawat

引用次数: 0

Prevalence and Pattern of Upper Gastrointestinal Lesions in Prospective Kidney Transplant Patients in Bangladesh. 孟加拉前瞻性肾移植患者上消化道病变的患病率和模式。

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Indian Journal of Nephrology Pub Date : 2025-07-01 Epub Date: 2024-11-28 DOI: 10.25259/IJN_66_2024

Sumona Islam, Md Anwarul Kabir, Amit Bari, Chanchal Kumar Ghosh, Md Razibul Alam, Nabila Tasneem Khan, Nowrin Tabassum, Farjana Sultana Rakhi, Suman Dey, Mohammed Reazuddin Danish

{"title":"Prevalence and Pattern of Upper Gastrointestinal Lesions in Prospective Kidney Transplant Patients in Bangladesh.","authors":"Sumona Islam, Md Anwarul Kabir, Amit Bari, Chanchal Kumar Ghosh, Md Razibul Alam, Nabila Tasneem Khan, Nowrin Tabassum, Farjana Sultana Rakhi, Suman Dey, Mohammed Reazuddin Danish","doi":"10.25259/IJN_66_2024","DOIUrl":"10.25259/IJN_66_2024","url":null,"abstract":"Background: Upper gastrointestinal (GI) lesions are common in patients with chronic kidney disease and may contribute to anemia and increased morbidity, especially in patients on hemodialysis (HD). They become even more significant in patients undergoing kidney transplantation about to be subjected to lifelong immunosuppressive drugs.Materials and methods: This cross-sectional study conducted at Bangabandhu Sheikh Mujib Medical University's Departments of Gastroenterology and Nephrology analyzed 128 prospective kidney transplant patients following upper GI endoscopy. Lesions were histopathologically examined and factors contributing to and consequences of the lesions were investigated.Results: A total of 52.3% patients had at least one upper GI lesion. Gastritis was the most prevalent one, comprising 55.7% of the lesions, followed by duodenitis (21.6%), ulcer (12.5%), esophagitis (2.3%), and others (8%). Lesions did not vary significantly between symptomatic and asymptomatic patients (p = 0.9). Those on HD had 3.6-fold higher odds of having a lesion (p = 0.005). Patients with lesions had significantly longer CKD duration (p = 0.0002). Mean hemoglobin level was 8.8 g/dl in those with lesions, which was significantly lower compared to those without lesion, who had a mean of 10.3 g/dl (p < 0.0001). Iron deficiency was more common in patients with lesions (p = 0.0004). The mean serum calcium level was significantly higher in patients with lesions (p = 0.0002).Conclusion: Upper GI lesions are fairly common in Bangladeshi CKD population. Routine endoscopic screening and treatment of asymptomatic lesions are recommended for advanced CKD patients in Bangladesh, given their frequency and potential impact.","PeriodicalId":13359,"journal":{"name":"Indian Journal of Nephrology","volume":"35 4","pages":"505-510"},"PeriodicalIF":0.8,"publicationDate":"2025-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12392186/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144952496","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0