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Indian Journal of Nephrology最新文献

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Novel Variations in KIRREL1 Gene and Infantile Onset Nephrotic Syndrome KIRREL1 基因的新变异与婴幼儿肾病综合征
IF 0.8
Indian Journal of Nephrology Pub Date : 2024-06-04 DOI: 10.25259/ijn_55_2024
Abhishek Abhinay, Aditi Agarwal, Ankur Singh, Nitish Kumar
{"title":"Novel Variations in KIRREL1 Gene and Infantile Onset Nephrotic Syndrome","authors":"Abhishek Abhinay, Aditi Agarwal, Ankur Singh, Nitish Kumar","doi":"10.25259/ijn_55_2024","DOIUrl":"https://doi.org/10.25259/ijn_55_2024","url":null,"abstract":"","PeriodicalId":13359,"journal":{"name":"Indian Journal of Nephrology","volume":null,"pages":null},"PeriodicalIF":0.8,"publicationDate":"2024-06-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141266852","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Assessment of Patient Awareness Regarding Chronic Kidney Disease Management in Santhal Parganas 桑塔尔帕尔加纳斯地区患者对慢性肾病管理的认识评估
IF 0.8
Indian Journal of Nephrology Pub Date : 2024-06-04 DOI: 10.25259/ijn_14_2024
Ayesha Juhi, Manoranjan Sahoo, Aman Kumar Gupta, M. Pinjar, A. Dhanvijay, Anita Kumari, Amita Kumari, Amita Singh, Himel Mondal
{"title":"Assessment of Patient Awareness Regarding Chronic Kidney Disease Management in Santhal Parganas","authors":"Ayesha Juhi, Manoranjan Sahoo, Aman Kumar Gupta, M. Pinjar, A. Dhanvijay, Anita Kumari, Amita Kumari, Amita Singh, Himel Mondal","doi":"10.25259/ijn_14_2024","DOIUrl":"https://doi.org/10.25259/ijn_14_2024","url":null,"abstract":"\u0000\u0000Chronic kidney disease (CKD) is a global health challenge, and effective self-management is crucial for optimal outcomes. Assessing the prevailing knowledge about CKD in patients can help strategies information education communication program to better manage the disease. This study evaluated the current knowledge of self-management of CKD among patients suffering from CKD in Santhal Parganas of Jharkhand state in India.\u0000\u0000\u0000This cross-sectional survey was conducted in a tertiary care teaching hospital situated in Deoghar, Jharkhand, India from June to December 2023. Patients suffering from CKD were enrolled for this study from the Outpatient Department. The Chronic Kidney Disease Self-Management Knowledge Tool (CKD-SMKT) was used to measure patients’ knowledge through face-to-face interviews conducted by a trained local surveyor.\u0000\u0000\u0000A total of 228 patients with a mean age of 52.63±10.65 years (men 136 [59.65%], women 92 [40.35%]) participated in the survey. All the patients (100%) gained knowledge about CKD from doctors, followed by other patients (63.6%) and relatives (41.23%). On average, 53.61% did not have proper knowledge about overall kidney disease. Correct knowledge about maintaining kidney health was among 38.1% of patients with 36.59% unsure about their knowledge and 25.31% declaring their lack of knowledge.\u0000\u0000\u0000A low level of knowledge about kidney health was found among the patients suffering from CKD in Santhal Parganas, a region with a tribal population with a low literacy rate. The identified knowledge gap emphasizes the need for a tailored educational program for CKD patients by doctors and patients relative.\u0000","PeriodicalId":13359,"journal":{"name":"Indian Journal of Nephrology","volume":null,"pages":null},"PeriodicalIF":0.8,"publicationDate":"2024-06-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141266303","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
An Unusual Case of Cryoglobulinemic Glomerulonephritis Revealing Waldenstrom’s Macroglobulinemia 揭示瓦尔登斯特罗姆巨球蛋白血症的冷球蛋白血症肾小球肾炎罕见病例
IF 0.8
Indian Journal of Nephrology Pub Date : 2024-06-04 DOI: 10.25259/ijn_102_2024
Sonia Dziri, N. Aicha, Awatef Azzabi, Wissal Sahtout, S. Nouira, Asma Fradi, Raja Boukadida, Yosra Guedri, S. Mrabet, Dorsaf Zellama
{"title":"An Unusual Case of Cryoglobulinemic Glomerulonephritis Revealing Waldenstrom’s Macroglobulinemia","authors":"Sonia Dziri, N. Aicha, Awatef Azzabi, Wissal Sahtout, S. Nouira, Asma Fradi, Raja Boukadida, Yosra Guedri, S. Mrabet, Dorsaf Zellama","doi":"10.25259/ijn_102_2024","DOIUrl":"https://doi.org/10.25259/ijn_102_2024","url":null,"abstract":"","PeriodicalId":13359,"journal":{"name":"Indian Journal of Nephrology","volume":null,"pages":null},"PeriodicalIF":0.8,"publicationDate":"2024-06-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141266680","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Zebra Bodies in the Kidney: Is it a Pathognomonic Finding of Fabry Disease? 肾脏中的斑马体：它是法布里病的病理诊断结果吗？
IF 0.8
Indian Journal of Nephrology Pub Date : 2024-06-04 DOI: 10.25259/ijn_392_23
Prem S. Patel, Prit P. Singh, A. Krishna, O. Kumar, Archana
{"title":"Zebra Bodies in the Kidney: Is it a Pathognomonic Finding of Fabry Disease?","authors":"Prem S. Patel, Prit P. Singh, A. Krishna, O. Kumar, Archana","doi":"10.25259/ijn_392_23","DOIUrl":"https://doi.org/10.25259/ijn_392_23","url":null,"abstract":"Zebra bodies are intralysosomal lamellar inclusion bodies. It is accepted as a specific feature of Fabry disease. However, it has been reported in many hereditary and acquired conditions. We are reporting Zebra bodies in the kidneys of cases with Rheumatoid Arthritis and hydroxychloroquine-induced phospholipidosis. Case 1: A 55-year-old male presented with hypertension and renal dysfunction. Serum ANA and anti-CCP antibodies were positive. A kidney biopsy revealed chronic tubulointerstitial nephritis with Zebra Bodies in the podocytes. Genetic analysis was negative for Fabry disease. Case 2: A 34-year-old female with Systemic Lupus Erythematosus on Hydroxychloroquine for a year presented with subnephrotic proteinuria. Serum ANA and anti-dsDNA antibodies were positive. Electron microscopy showed lamellated osmiophilic inclusion bodies in the tubular and visceral epithelial cells. Thus, Zebra bodies are not pathognomonic for Fabry disease and Rheumatoid Arthritis should also be considered in the differential diagnosis, particularly if family or drug history is negative.","PeriodicalId":13359,"journal":{"name":"Indian Journal of Nephrology","volume":null,"pages":null},"PeriodicalIF":0.8,"publicationDate":"2024-06-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141267822","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Trilateral Reflux in a Child with Renal Transplant 肾移植患儿的三侧血流反流
IF 0.8
Indian Journal of Nephrology Pub Date : 2024-06-04 DOI: 10.25259/ijn_105_2024
Kushal Kotia, Anmol Bhatia, K. Sodhi, M. Malik, Akshay Saxena
{"title":"Trilateral Reflux in a Child with Renal Transplant","authors":"Kushal Kotia, Anmol Bhatia, K. Sodhi, M. Malik, Akshay Saxena","doi":"10.25259/ijn_105_2024","DOIUrl":"https://doi.org/10.25259/ijn_105_2024","url":null,"abstract":"","PeriodicalId":13359,"journal":{"name":"Indian Journal of Nephrology","volume":null,"pages":null},"PeriodicalIF":0.8,"publicationDate":"2024-06-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141266686","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
A Mysterious Case of Pleuroperitoneal Leak Leading to Recurrent Hydrothorax in a Child with Nephrotic Syndrome 肾病综合征患儿胸膜漏导致反复积水的神秘病例
IF 0.8
Indian Journal of Nephrology Pub Date : 2024-06-04 DOI: 10.25259/ijn_567_23
Niranjan A. Vijayakumar, Jasmine Sethi, Nishant Nadda, V. Venkatasubramanian, B. Mittal
{"title":"A Mysterious Case of Pleuroperitoneal Leak Leading to Recurrent Hydrothorax in a Child with Nephrotic Syndrome","authors":"Niranjan A. Vijayakumar, Jasmine Sethi, Nishant Nadda, V. Venkatasubramanian, B. Mittal","doi":"10.25259/ijn_567_23","DOIUrl":"https://doi.org/10.25259/ijn_567_23","url":null,"abstract":"We describe a young girl of steroid resistant nephrotic syndrome with rapidly reaccumulating right sided pleural effusion. On evaluation, the patient was diagnosed with right side pleuro-peritoneal leak leading to recurrent right hydrothorax. To the best of our knowledge, hydrothorax due to transdiaphragmatic shunting in a nephrotic patient has not been reported earlier.","PeriodicalId":13359,"journal":{"name":"Indian Journal of Nephrology","volume":null,"pages":null},"PeriodicalIF":0.8,"publicationDate":"2024-06-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141266372","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Kidney Disease Pattern in Tribal Belt of Rajasthan: Kidney Biopsy Experience of Seven Years 拉贾斯坦邦部落地带的肾病模式：七年的肾活检经验
IF 0.8
Indian Journal of Nephrology Pub Date : 2024-06-04 DOI: 10.25259/ijn_547_23
Mukesh Barjatiya, Anurag Jain, Rajesh Jhorawat
{"title":"Kidney Disease Pattern in Tribal Belt of Rajasthan: Kidney Biopsy Experience of Seven Years","authors":"Mukesh Barjatiya, Anurag Jain, Rajesh Jhorawat","doi":"10.25259/ijn_547_23","DOIUrl":"https://doi.org/10.25259/ijn_547_23","url":null,"abstract":"","PeriodicalId":13359,"journal":{"name":"Indian Journal of Nephrology","volume":null,"pages":null},"PeriodicalIF":0.8,"publicationDate":"2024-06-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141266213","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
NELL-1 as a Target Antigen in Asbestosis Associated Membranous Nephropathy — A Case Report NELL-1 作为石棉沉滞症相关膜性肾病的靶抗原--一份病例报告
IF 0.8
Indian Journal of Nephrology Pub Date : 2024-06-04 DOI: 10.25259/ijn_65_2024
B. Sundaram, Nabadwip Pathak, M. Ambroise, Selva Micheal Papou
{"title":"NELL-1 as a Target Antigen in Asbestosis Associated Membranous Nephropathy — A Case Report","authors":"B. Sundaram, Nabadwip Pathak, M. Ambroise, Selva Micheal Papou","doi":"10.25259/ijn_65_2024","DOIUrl":"https://doi.org/10.25259/ijn_65_2024","url":null,"abstract":"An 80-year-old male with a history of prolonged asbestos exposure presented with 24-hour urine protein of 8 gm, and serum albumin of 1.7 gm/dl. Renal biopsy disclosed features of membranous nephropathy. Immunohistochemistry showed positivity for neural epidermal-like growth factor- like 1 (NELL1) (2+/3+). Further assessment uncovered an incidental finding of asbestos-related pleural plaques and left hemithorax volume loss on computed tomography (CT) chest, leading to a diagnosis of asbestosis. This case highlights the rare association between asbestosis and NELL-1 positive membranous nephropathy.","PeriodicalId":13359,"journal":{"name":"Indian Journal of Nephrology","volume":null,"pages":null},"PeriodicalIF":0.8,"publicationDate":"2024-06-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141268475","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Comparison of Dialysis Catheter Insertion and Complications Under Ultrasound Guidance with or without Fluoroscopic Assistance: A Randomized Study 有无透视辅助超声引导下的透析导管插入及并发症比较：随机研究
IF 0.8
Indian Journal of Nephrology Pub Date : 2024-06-04 DOI: 10.25259/ijn_414_23
Sushma Konnepati, Jasmine Sethi, Anupam Lal, Raja Ramachandran, Manish Rathi
{"title":"Comparison of Dialysis Catheter Insertion and Complications Under Ultrasound Guidance with or without Fluoroscopic Assistance: A Randomized Study","authors":"Sushma Konnepati, Jasmine Sethi, Anupam Lal, Raja Ramachandran, Manish Rathi","doi":"10.25259/ijn_414_23","DOIUrl":"https://doi.org/10.25259/ijn_414_23","url":null,"abstract":"\u0000\u0000Fluoroscopy is considered to be the gold standard and an essential requirement for catheter insertion. However, there is a paucity of data regarding the outcomes in ultrasound (USG)-guided insertion with and without fluoroscopy. We compared the complications of USG-guided tunneled dialysis catheter (TDC) insertion with and without fluoroscopy assistance.\u0000\u0000\u0000This was a single-center randomized controlled trial (RCT) done in a tertiary hospital in North India. After screening 153 patients, 149 were enrolled: 87 were randomized into USG-guided insertion without fluoroscopy (group A) and 62 were randomized into USG-guided insertion with fluoroscopy (group B). All insertions were done in a dedicated procedure room by trained nephrologists. Outcomes were analyzed at baseline and at 1-month follow-up. Mechanical complications as well as infective and thrombotic complications were compared between both the groups.\u0000\u0000\u0000TDC insertion was successful (100%) in all the study participants (N = 149). One hundred twenty-nine catheters (86.5%) were inserted in the first attempt, 19 (12.5%) in the second attempt, and one catheter insertion required three attempts for insertion. The mean age of study participants was 43 years (±16.5), and males constituted 63% of the study cohort. Baseline laboratory characteristics of the two groups were comparable. The mean time of catheter insertion was 41.26 min (standard deviation [SD] 11.8) in group A and 47.74 min (SD 17.2) in group B (P = 0.007). The mean score of ease of catheter insertion, exit site bleed, infective and mechanical complications were not different between the two groups.\u0000\u0000\u0000Our study concluded that fluoroscopy has no additional advantage in reducing mechanical, infective, or thrombotic complications. In experienced hands, USG-guided TDC insertion without fluoroscopy assistance is as good as the insertion done with fluoroscopy assistance, with a shorter procedure time.\u0000","PeriodicalId":13359,"journal":{"name":"Indian Journal of Nephrology","volume":null,"pages":null},"PeriodicalIF":0.8,"publicationDate":"2024-06-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141268289","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
NELL-1 Associated Membranous Nephropathy - A Case Series from India NELL-1 相关膜性肾病--来自印度的一个病例系列
IF 0.8
Indian Journal of Nephrology Pub Date : 2024-06-04 DOI: 10.25259/ijn_326_23
Yogita Sharma, Akash Jain, Pallav Gupta, V. Tiwari, Anurag Gupta, V. Bhargava, M. Malik, Ashwani K Gupta, A. Bhalla, D. Rana
{"title":"NELL-1 Associated Membranous Nephropathy - A Case Series from India","authors":"Yogita Sharma, Akash Jain, Pallav Gupta, V. Tiwari, Anurag Gupta, V. Bhargava, M. Malik, Ashwani K Gupta, A. Bhalla, D. Rana","doi":"10.25259/ijn_326_23","DOIUrl":"https://doi.org/10.25259/ijn_326_23","url":null,"abstract":"Neural epidermal growth factor-like 1 (NELL-1) is responsible for a substantial proportion of cases of PLA2R-negative primary membranous nephropathy (MN). To investigate the occurrence, association, and treatment responses, we carried out this ambispective study. In the study, nine (10%) of all patients with MN at our center were found to be NELL-1 positive. On follow up, all patients recieved immunosuppression (steroids, cyclophosphamide or rituximab). Five patients were in complete remission, while one patient had partial remission, two patients had a progressive decline in kidney function, and one patient was lost to follow-up early. No link was found with malignancies, traditional Indian medicines or infection.","PeriodicalId":13359,"journal":{"name":"Indian Journal of Nephrology","volume":null,"pages":null},"PeriodicalIF":0.8,"publicationDate":"2024-06-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141265930","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
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