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Indian Journal of Nephrology最新文献

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Assessing the Practice of Infection Control Among Dialysis Staff in Dialysis Centers in Northeast India. 印度东北部透析中心透析人员感染控制实践评估
IF 0.8
Indian Journal of Nephrology Pub Date : 2025-07-01 Epub Date: 2024-09-05 DOI: 10.25259/ijn_573_23
Takhellambam Brojen Singh, Beningwar Jimmy Hulang, Loukrakpam Sharatchandra Singh, Akash Singh, Sourav Misra, Swati Bhagat, A Aarthi, Ngairangbam Archana, Pankaj Puri
{"title":"Assessing the Practice of Infection Control Among Dialysis Staff in Dialysis Centers in Northeast India.","authors":"Takhellambam Brojen Singh, Beningwar Jimmy Hulang, Loukrakpam Sharatchandra Singh, Akash Singh, Sourav Misra, Swati Bhagat, A Aarthi, Ngairangbam Archana, Pankaj Puri","doi":"10.25259/ijn_573_23","DOIUrl":"10.25259/ijn_573_23","url":null,"abstract":"<p><strong>Background: </strong>Chronic kidney disease patients on maintenance hemodialysis have multiple co-morbidities and high risk of infections. This study was conducted to assess the idea and practice of infection control measures in dialysis units in northeast India.</p><p><strong>Materials and methods: </strong>This observational descriptive study was conducted among the participants of the 5<sup>th</sup> hemodialysis technician's conference, held at Guwahati on 29 and 30<sup>th</sup> October 2022. Data was collected through questionnaire prepared from Center for Diseases Control and Prevention 2016 Infection Prevention and Control Assessment Tool for hemodialysis with some additional parameters.</p><p><strong>Results: </strong>A total of 200 dialysis staff working in different dialysis units of northeast India participated in the study. Among infection control practices, 38% of participants said that their centers had no dedicated area for parenteral medication preparation. Twenty two percent did not clean the dialysis machine after each session. Thirty percent of participants responded that they had no regular training for infection control practices. Sixteen percent reported inadequate hand hygiene facilities near waiting areas.</p><p><strong>Conclusion: </strong>Dialysis staff has a crucial role in providing good standard dialysis care in ESRD patients. Dialysis facilities should have written policies on infection prevention and control and provide regular training to dialysis staff.</p>","PeriodicalId":13359,"journal":{"name":"Indian Journal of Nephrology","volume":"35 4","pages":"516-519"},"PeriodicalIF":0.8,"publicationDate":"2025-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12392234/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144952356","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Fever of Unknown Origin in a Renal Transplant Recipient. 肾移植受者不明原因发热。
IF 0.8
Indian Journal of Nephrology Pub Date : 2025-07-01 Epub Date: 2024-08-22 DOI: 10.25259/IJN_10_2024
Subashri Mohanasundaram, N D Srinivasaprasad, Edwin Fernando, K Thirumalvalavan, Sujit Surendran, Poongodi Annadurai
{"title":"Fever of Unknown Origin in a Renal Transplant Recipient.","authors":"Subashri Mohanasundaram, N D Srinivasaprasad, Edwin Fernando, K Thirumalvalavan, Sujit Surendran, Poongodi Annadurai","doi":"10.25259/IJN_10_2024","DOIUrl":"10.25259/IJN_10_2024","url":null,"abstract":"<p><p>A syndrome of exaggerated lymphocytic proliferation and activation, called hemophagocytic lymphohistiocytosis (HLH) can occur primarily due to genetic mutation, in children and secondary to infection, malignancy or autoimmunity in adults. It is characterized by a misdirected activation of immune system, which causes cytokine release from macrophages and cytotoxic cells, in an uncontrolled fashion. Most treatment protocols are formulated for primary hemophagocytic histiocytosis, which occurs in children, whereas awareness and therapeutic guidelines for the secondary form of the disease which affects predominantly the adults is limited. We present a 29 year old renal transplant recipient presenting with fever of unknown origin found to have HLH secondary to tuberculosis, who responded to anti-tuberculous treatment.</p>","PeriodicalId":13359,"journal":{"name":"Indian Journal of Nephrology","volume":"35 4","pages":"570-572"},"PeriodicalIF":0.8,"publicationDate":"2025-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12392228/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144952461","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Urinothorax in a Late Kidney Transplant Following Graft Biopsy. 移植肾活检后晚期尿胸。
IF 0.8
Indian Journal of Nephrology Pub Date : 2025-07-01 Epub Date: 2025-03-12 DOI: 10.25259/IJN_472_2024
Indranil Ghosh, Sukhwinder Singh Sangha, Puneet Saxena, Neeraj Kumar
{"title":"Urinothorax in a Late Kidney Transplant Following Graft Biopsy.","authors":"Indranil Ghosh, Sukhwinder Singh Sangha, Puneet Saxena, Neeraj Kumar","doi":"10.25259/IJN_472_2024","DOIUrl":"10.25259/IJN_472_2024","url":null,"abstract":"","PeriodicalId":13359,"journal":{"name":"Indian Journal of Nephrology","volume":"35 4","pages":"584-585"},"PeriodicalIF":0.8,"publicationDate":"2025-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12392216/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144952676","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Intraperitoneally Administered Vancomycin Results in Suboptimal Serum and Peritoneal Effluent Drug Levels in Patients with PD-related Peritonitis. 腹膜注射万古霉素导致pd相关性腹膜炎患者血清和腹膜流出液药物水平不理想。
IF 0.8
Indian Journal of Nephrology Pub Date : 2025-07-01 Epub Date: 2024-09-19 DOI: 10.25259/IJN_59_2024
Ezhilnilavan Sampath, Kapil Navin Sejpal, Apurba S Sastry, Sandhiya Selvarajan, P S Priyamvada, Sreejith Parameswaran
{"title":"Intraperitoneally Administered Vancomycin Results in Suboptimal Serum and Peritoneal Effluent Drug Levels in Patients with PD-related Peritonitis.","authors":"Ezhilnilavan Sampath, Kapil Navin Sejpal, Apurba S Sastry, Sandhiya Selvarajan, P S Priyamvada, Sreejith Parameswaran","doi":"10.25259/IJN_59_2024","DOIUrl":"10.25259/IJN_59_2024","url":null,"abstract":"<p><strong>Background: </strong>Intraperitoneal vancomycin is commonly used to treat peritoneal dialysis (PD)-related peritonitis. Therapeutic drug level monitoring helps optimize the use of vancomycin in CKD patients. We studied whether sufficient serum levels were achieved in patients with PD-related peritonitis treated with the commonly used dose of vancomycin in patients with end stage renal disease.</p><p><strong>Materials and methods: </strong>All consecutive patients with PD-related peritonitis during 19 months were studied. Patients received IP Vancomycin 15 mg/kg Q96H and amikacin 2 mg/kg while awaiting culture reports. Vancomycin concentration in serum and dialysate was determined by a validated liquid chromatography-tandem mass spectrometry assay at 1, 12, 24, and 96 h. The primary outcome was the drug levels in serum and peritoneal fluid, and the secondary outcome was peritonitis treatment failure.</p><p><strong>Results: </strong>A total of 45 episodes of PD-related peritonitis were treated, of which 41 fulfilled the inclusion criteria and were included in the PK analysis. Recommended serum vancomycin trough level of >15 mg/L was achieved in only two cases. Twenty-one episodes required catheter removal.</p><p><strong>Conclusion: </strong>In patients with PD-related peritonitis, intermittent intraperitoneal administration of 15 mg/kg of vancomycin every 96 h does not achieve the recommended serum and dialysate levels of vancomycin. There is an urgent need for pharmacokinetic studies on commonly used IP antibiotics in the PD population to facilitate correct dose recommendations.</p>","PeriodicalId":13359,"journal":{"name":"Indian Journal of Nephrology","volume":"35 4","pages":"524-529"},"PeriodicalIF":0.8,"publicationDate":"2025-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12392212/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144952431","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Disseminated Adenovirus Infection in Renal Transplant Recipients. 肾移植受者播散性腺病毒感染
IF 0.8
Indian Journal of Nephrology Pub Date : 2025-07-01 Epub Date: 2025-05-06 DOI: 10.25259/IJN_67_2025
Karthik Sunder, M Navya, Jui Athavale, Saravanan Margabandhu, Elankumaran Krishnan, Kulaseharan Venugopal Haribabu, Ram Gopalakrishnan, Sheba Jacob, Praveen Balaguru
{"title":"Disseminated Adenovirus Infection in Renal Transplant Recipients.","authors":"Karthik Sunder, M Navya, Jui Athavale, Saravanan Margabandhu, Elankumaran Krishnan, Kulaseharan Venugopal Haribabu, Ram Gopalakrishnan, Sheba Jacob, Praveen Balaguru","doi":"10.25259/IJN_67_2025","DOIUrl":"10.25259/IJN_67_2025","url":null,"abstract":"<p><p>Adenoviruses rarely cause graft dysfunction in renal transplants and are generally overlooked. We describe two recipients with fever who were diagnosed with disseminated adenovirus infection that resolved with immunosuppression reduction.</p>","PeriodicalId":13359,"journal":{"name":"Indian Journal of Nephrology","volume":"35 4","pages":"551-552"},"PeriodicalIF":0.8,"publicationDate":"2025-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12392235/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144952468","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Post Transplant Membranous Nephropathy: A 10-year Single-Centre Experience. 移植后膜性肾病：10年单中心经验。
IF 0.8
Indian Journal of Nephrology Pub Date : 2025-07-01 Epub Date: 2025-05-08 DOI: 10.25259/IJN_150_2025
Payal Gaggar, Rahul R Nair, Avinash Pratapsingh Thakur, Sree Bhushan Raju
{"title":"Post Transplant Membranous Nephropathy: A 10-year Single-Centre Experience.","authors":"Payal Gaggar, Rahul R Nair, Avinash Pratapsingh Thakur, Sree Bhushan Raju","doi":"10.25259/IJN_150_2025","DOIUrl":"10.25259/IJN_150_2025","url":null,"abstract":"<p><p>Membranous nephropathy (MN) post-renal transplant can present as a recurrent or <i>de novo</i> disease, often impacting graft outcomes. We retrospectively analyzed 530 allograft biopsies over 10 years, identifying five MN cases (∼1%): four <i>de novo</i> (0.8%) and one recurrent. Among the former, 75% had concurrent antibody-mediated rejection (AMR); serum anti-PLA2R and tissue PLA2R were detected in 25%. All patients received plasmapheresis and low-dose intravenous immunoglobulin, with one requiring rituximab. Two patients stabilized, one experienced graft loss, and one attained complete remission. The recurrent MN case presented 10 years post-transplant and partially responded to rituximab. AMR influenced prognosis, with a 33% graft loss rate in <i>de novo</i> MN. Individualized treatment based on etiology, particularly targeting rejection, may improve outcomes. The study highlights the need for early diagnosis and personalized management in post-transplant MN.</p>","PeriodicalId":13359,"journal":{"name":"Indian Journal of Nephrology","volume":"35 4","pages":"552-554"},"PeriodicalIF":0.8,"publicationDate":"2025-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12392203/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144952580","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Mycophenolate-Induced Dysphagia in a Kidney Transplant Recipient. 肾移植受者霉酚酸诱导的吞咽困难。
IF 0.8
Indian Journal of Nephrology Pub Date : 2025-05-01 Epub Date: 2024-12-26 DOI: 10.25259/IJN_680_2024
Kalathil K Sureshkumar, Robert Ryhal, Khaled Nashar, Reem Daloul
{"title":"Mycophenolate-Induced Dysphagia in a Kidney Transplant Recipient.","authors":"Kalathil K Sureshkumar, Robert Ryhal, Khaled Nashar, Reem Daloul","doi":"10.25259/IJN_680_2024","DOIUrl":"https://doi.org/10.25259/IJN_680_2024","url":null,"abstract":"","PeriodicalId":13359,"journal":{"name":"Indian Journal of Nephrology","volume":"35 3","pages":"446-447"},"PeriodicalIF":0.8,"publicationDate":"2025-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12065595/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143991848","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Nature's Cure or Kidney Curse? The Nephrotoxic Potential of Indigenous Remedies. 自然疗法还是肾脏诅咒？土着疗法的肾毒性潜力。
IF 0.8
Indian Journal of Nephrology Pub Date : 2025-05-01 Epub Date: 2024-10-24 DOI: 10.25259/IJN_321_2024
Jasmine Sethi, Urmila Anandh, Vivekanand Jha
{"title":"Nature's Cure or Kidney Curse? The Nephrotoxic Potential of Indigenous Remedies.","authors":"Jasmine Sethi, Urmila Anandh, Vivekanand Jha","doi":"10.25259/IJN_321_2024","DOIUrl":"https://doi.org/10.25259/IJN_321_2024","url":null,"abstract":"<p><p>Traditional medicine refers to a diverse range of health and healing practices used by Indigenous peoples that incorporate plants, animals, and the spiritual realm for the diagnosis and treatment of illness or maintenance of health and well-being. While these practices hold significant cultural value, there is growing evidence of potential nephrotoxicity associated with some traditional indigenous medicines (TIMs). In this review, we explore the various clinical manifestations of nephrotoxicity induced by TIMs. Nephrotoxicity can result from various factors, including the intrinsic toxicity of certain herbs, contamination with heavy metals, inappropriate dosages, and interaction with conventional medications. This review highlights the importance of monitoring kidney function in patients using TIMs and calls for increased awareness and regulation to ensure the safe use of these traditional therapies.</p>","PeriodicalId":13359,"journal":{"name":"Indian Journal of Nephrology","volume":"35 3","pages":"335-342"},"PeriodicalIF":0.8,"publicationDate":"2025-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12065597/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143991408","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Obinutuzumab as a Promising Treatment for Membranous Nephropathy. Obinutuzumab作为膜性肾病的有希望的治疗方法。
IF 0.8
Indian Journal of Nephrology Pub Date : 2025-05-01 Epub Date: 2024-10-10 DOI: 10.25259/IJN_391_2024
Priti Meena, Raja Ramachandran
{"title":"Obinutuzumab as a Promising Treatment for Membranous Nephropathy.","authors":"Priti Meena, Raja Ramachandran","doi":"10.25259/IJN_391_2024","DOIUrl":"https://doi.org/10.25259/IJN_391_2024","url":null,"abstract":"","PeriodicalId":13359,"journal":{"name":"Indian Journal of Nephrology","volume":"35 3","pages":"322-323"},"PeriodicalIF":0.8,"publicationDate":"2025-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12065589/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143990047","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Challenges and Considerations in Metformin Use for ADPKD: A Commentary on Recent Findings. 二甲双胍用于ADPKD的挑战和考虑：对最近发现的评论。
IF 0.8
Indian Journal of Nephrology Pub Date : 2025-05-01 Epub Date: 2024-11-06 DOI: 10.25259/IJN_513_2024
Amol N Patil, Mahendra Pratap Singh, Pramod Rawat, Sanjit Sah, Prakasini Satapathy
{"title":"Challenges and Considerations in Metformin Use for ADPKD: A Commentary on Recent Findings.","authors":"Amol N Patil, Mahendra Pratap Singh, Pramod Rawat, Sanjit Sah, Prakasini Satapathy","doi":"10.25259/IJN_513_2024","DOIUrl":"https://doi.org/10.25259/IJN_513_2024","url":null,"abstract":"","PeriodicalId":13359,"journal":{"name":"Indian Journal of Nephrology","volume":"35 3","pages":"443"},"PeriodicalIF":0.8,"publicationDate":"2025-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12065576/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143998459","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
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