{"title":"Patient education tools for chronic pain medications: Artificial intelligence chatbot versus traditional patient information leaflets.","authors":"Hinpetch Daungsupawong, Viroj Wiwanitkit","doi":"10.4103/ija.ija_794_24","DOIUrl":"10.4103/ija.ija_794_24","url":null,"abstract":"","PeriodicalId":13339,"journal":{"name":"Indian Journal of Anaesthesia","volume":"68 12","pages":"1111-1112"},"PeriodicalIF":2.9,"publicationDate":"2024-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11812515/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143407405","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Sergey M Efremov, Alexey Y Kulikov, Valeria P Govorushkina, Daniil D Sidorov, Alexey A Ladutko, Oleg V Kuleshov
{"title":"Effects of intracuff and intravenous lignocaine on recovery from anaesthesia after thyroid surgery. A single-centre randomised double-blind placebo-controlled trial (The IOLANT study).","authors":"Sergey M Efremov, Alexey Y Kulikov, Valeria P Govorushkina, Daniil D Sidorov, Alexey A Ladutko, Oleg V Kuleshov","doi":"10.4103/ija.ija_487_24","DOIUrl":"10.4103/ija.ija_487_24","url":null,"abstract":"<p><strong>Background and aims: </strong>Despite evidence that local intracuff alkalinised lignocaine may reduce the incidence of exaggerated laryngeal reflexes after thyroid surgery, its effects on the quality of recovery (QoR) from anaesthesia remain unknown. This study aimed to test if local intracuff alkalinised lignocaine improves the QoR from anaesthesia after thyroid surgery compared to placebo.</p><p><strong>Methods: </strong>Patients over 45 years old scheduled for thyroid surgery with electromyographic monitoring under general anaesthesia were enroled in a randomised, single-centre, double-blind, placebo-controlled trial. They were randomised into three groups (1:1:1 ratio): intravenous lignocaine (IVL), topical and intracuff lignocaine (TL), and placebo. The sample size was initially set at 231, but the study was terminated early after an interim analysis of 110 patients showed no significant difference between groups. The primary outcome was the QoR-40 score 24 hours post-surgery. Secondary outcomes included rates of arterial hypotension, coughing during emergence, bispectral index (BIS) values, and electromyographic monitoring characteristics.</p><p><strong>Results: </strong>An interim analysis after 110 patients showed mean QoR-40 scores of 185 (standard deviation(SD): 11.4) (placebo), 186.1 (SD: 13.6) (IVL), and 185.1 (SD: 14.3) (TL) (<i>P</i> = 0.662). Mean differences were 1.1 (IVL vs placebo, 95%CI: -5.03, 7.15, z = 0.347) and 0.1 (TL vs placebo, 95%CI: -6.02, 6.23, z = 0.035). The study was stopped due to lack of effectiveness as the superiority of IVL and TL was not demonstrated. No differences were found in secondary outcomes.</p><p><strong>Conclusion: </strong>Neither IVL nor TL improved the QoR from anaesthesia and did not affect electromyographic monitoring in low-risk thyroid surgery.</p>","PeriodicalId":13339,"journal":{"name":"Indian Journal of Anaesthesia","volume":"68 12","pages":"1055-1061"},"PeriodicalIF":2.9,"publicationDate":"2024-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11812505/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143407389","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Enhancing patient education with ChatGPT: Critical insights and future directions.","authors":"Javed K Sheikh, Shahab S Sohail, Sultan Alam","doi":"10.4103/ija.ija_784_24","DOIUrl":"10.4103/ija.ija_784_24","url":null,"abstract":"","PeriodicalId":13339,"journal":{"name":"Indian Journal of Anaesthesia","volume":"68 12","pages":"1112-1113"},"PeriodicalIF":2.9,"publicationDate":"2024-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11812512/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143407395","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Transnasal humidified rapid insufflation ventilatory exchange (THRIVE): A game changer in apnoeic anaesthesia for shared airway procedures - A retrospective study.","authors":"Minal Harde, Manish Patil, Anjana Sahu, Charulata Deshpande, R Akhilnath, Kalpesh Pawara","doi":"10.4103/ija.ija_603_24","DOIUrl":"10.4103/ija.ija_603_24","url":null,"abstract":"<p><strong>Background and aims: </strong>Transnasal humidified rapid insufflation ventilatory exchange (THRIVE) is a valuable adjunct during apnoea. Conventional techniques of apnoeic anaesthesia have limitations. THRIVE helps to maintain oxygenation during the apnoeic periods in tubeless airway surgeries. We aimed to evaluate tubeless apnoeic anaesthesia in shared airways using THRIVE to determine safe apnoea time.</p><p><strong>Methods: </strong>Two years of retrospective data were collected at a tertiary care centre, which included 60 patients in whom THRIVE was used for apnoeic anaesthesia. We appraised tubeless apnoeic anaesthesia in shared airways using THRIVE to determine safe apnoea time. Data on oxygenation, haemodynamic parameters, ventilation and the perioperative course were also collected. The data were analysed using GNU PSPP 1.0.1 software.</p><p><strong>Results: </strong>The patients' mean age was 48.53 [standard deviation (SD):16.62] years. Microlaryngoscopy [24 (40%)], rigid bronchoscopy [12 (20%)], tracheal dilatation [12 (20%)] and foreign body removal [8 (13.3%)] were the common procedures. The mean apnoea time was 14.5 (SD: 2.05) min. Patients maintained normal haemodynamic parameters, with a mean oxygen saturation of 98% during apnoea. The highest mean end-tidal carbon dioxide at the end of apnoea was 55 mmHg, which normalised after 1-2 min of ventilation. Intermittent ventilation was done in eight patients as the apnoea time exceeded 20 min. Emergence and recovery were smooth, and none of the patients developed any complications throughout the procedure.</p><p><strong>Conclusion: </strong>THRIVE can be effectively and safely used for tubeless apnoeic anaesthesia, with an uninterrupted apnoea time of approximately 15 min without complications.</p>","PeriodicalId":13339,"journal":{"name":"Indian Journal of Anaesthesia","volume":"68 12","pages":"1075-1080"},"PeriodicalIF":2.9,"publicationDate":"2024-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11812517/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143407409","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Near-infrared spectroscopy during organ donation in brain-dead patients.","authors":"Michele Carron, Enrico Tamburini","doi":"10.4103/ija.ija_827_24","DOIUrl":"10.4103/ija.ija_827_24","url":null,"abstract":"<p><p>Near-infrared spectroscopy (NIRS) is essential for monitoring cerebral oxygenation in anaesthesia and critical care, offering non-invasive insights into regional cerebral oxygen saturation (rSO<sub>2</sub>). However, extracerebral contamination can compromise NIRS accuracy. The O3™ regional oximetry system, with its advanced multi-wavelength technology, may contribute by providing more accurate measurements. In a study involving brain-dead organ donors, near-normal rSO<sub>2</sub> values were initially observed despite cerebral anoxia, suggesting extracerebral signal interference. Following aortic clamping and cessation of circulation, rSO<sub>2</sub> levels dropped but remained above zero, indicating potential limitations in accurately detecting severe hypoxia. This case study demonstrated the effectiveness of the O3™ system in monitoring rSO<sub>2</sub> in such critical situations, uniquely supported by the cerebral haemoglobin index, oxygenated haemoglobin index, and deoxygenated haemoglobin index. The findings emphasise the importance of understanding oxygen transport mechanisms and haemoglobin affinity to accurately interpret NIRS data, especially in brain-dead patients and organ donation procedures.</p>","PeriodicalId":13339,"journal":{"name":"Indian Journal of Anaesthesia","volume":"68 12","pages":"1095-1098"},"PeriodicalIF":2.9,"publicationDate":"2024-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11812511/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143407401","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Efficacy of local anaesthetic peri-femoral artery injection compared to subcutaneous infiltration in combination with femoral and sciatic nerve blocks for reducing thigh tourniquet-induced hypertension during lower-limb surgery under general anaesthesia: A randomised controlled double-blinded trial.","authors":"Chonruethai Tangkittithaworn, Wirinaree Kampitak, Tanawat Benjamungkalarak, Jirun Apinun","doi":"10.4103/ija.ija_968_24","DOIUrl":"10.4103/ija.ija_968_24","url":null,"abstract":"<p><strong>Background and aims: </strong>Tourniquet-induced hypertension (TH) remains an unresolved issue. Various techniques, such as peripheral nerve blocks, peri-femoral artery blocks, and subcutaneous infiltration, have been explored to address this. The primary objective was to compare the incidence of TH during lower-limb surgery under general anaesthesia between peri-femoral artery block and subcutaneous infiltration, combined with femoral and sciatic nerve blocks. Secondary objectives included intraoperative intravenous fentanyl and antihypertensive uses, as well as postoperative pain scores.</p><p><strong>Methods: </strong>This single-centre, double-blind, randomised controlled trial involved 58 patients scheduled for elective lower-limb surgery. Participants were assigned to the peri-femoral artery block (P-FAB) or subcutaneous infiltration (SI) groups. All patients received general anaesthesia alongside femoral and sciatic nerve blocks. TH was defined as a 30% increase in systolic blood pressure from baseline. Pain was assessed using a numerical rating scale in the post-anaesthetic care unit and at 4, 8, 12, and 24 h post-surgery. Unpaired <i>t</i>-test, Chi-square, and Mann-Whitney U test were used for analysis. A <i>P</i> value less than 0.05 was considered to be statistically significant.</p><p><strong>Results: </strong>There were no significant differences in the incidence of TH between the P-FAB and SI groups (<i>P</i> = 1.00). Similarly, no significant differences were observed in intraoperative fentanyl (<i>P</i> = 0.459) or antihypertensive use (<i>P</i> = 0.992). Pain scores across all measured aspects, including thigh and incision sites, were also not significantly different between groups (<i>P</i> > 0.05).</p><p><strong>Conclusions: </strong>In lower-limb surgery, adding a peri-femoral artery block to general anaesthesia with femoral and sciatic nerve blocks did not reduce the incidence of TH compared to subcutaneous infiltration.</p>","PeriodicalId":13339,"journal":{"name":"Indian Journal of Anaesthesia","volume":"68 12","pages":"1035-1042"},"PeriodicalIF":2.9,"publicationDate":"2024-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11812501/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143407393","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Fatal air embolism in an infant during vitrectomy - A case report and review of literature.","authors":"Swarnika Singh, Vinod Kumar Verma, Swati Singh, Heena Agrawal, Mudassir Alam","doi":"10.4103/ija.ija_524_24","DOIUrl":"10.4103/ija.ija_524_24","url":null,"abstract":"","PeriodicalId":13339,"journal":{"name":"Indian Journal of Anaesthesia","volume":"68 12","pages":"1105-1106"},"PeriodicalIF":2.9,"publicationDate":"2024-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11812500/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143407398","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Patient education tools for chronic pain medications, AI versus traditional PILs - Clarifications.","authors":"Prakash Gondode, Sakshi Duggal, Neha Garg, Surendar Sethupathy, Omshubham Asai, Pooja Lohakare","doi":"10.4103/ija.ija_930_24","DOIUrl":"10.4103/ija.ija_930_24","url":null,"abstract":"","PeriodicalId":13339,"journal":{"name":"Indian Journal of Anaesthesia","volume":"68 12","pages":"1113-1114"},"PeriodicalIF":2.9,"publicationDate":"2024-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11812516/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143407404","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Pericapsular nerve group (PENG) block versus supra-inguinal fascia iliaca (SIFI) block for functional outcome in patients undergoing hip surgeries - A randomised controlled study.","authors":"Tanusha Saini, Meenakshi Aggarwal, Udeyana Singh, Mirley Rupinder Singh","doi":"10.4103/ija.ija_838_24","DOIUrl":"10.4103/ija.ija_838_24","url":null,"abstract":"<p><strong>Background and aims: </strong>In hip surgeries, the pericapsular nerve group (PENG) block and supra-inguinal fascia iliaca (SIFI) block are commonly employed perioperative regional analgesia techniques. This study aimed to compare functional outcomes regarding quadriceps muscle strength and weight-bearing capacity between PENG and SIFI blocks after hip surgery.</p><p><strong>Methods: </strong>In this single-centre, double-blinded, randomised trial, 60 patients undergoing hip surgeries under subarachnoid block were randomised into either Group P (PENG block) or Group S (SIFI block). Blocks were administered under ultrasound guidance with 30 mL of 0.2% ropivacaine and 4 mg dexamethasone. Functional mobility was assessed 24 and 48 h postoperatively by measuring quadriceps strength and maximum weight-bearing capacity. Analgesic efficacy was also evaluated by comparing visual analogue score (VAS) scores at 24 h, total opioid consumption over 24 h, and duration of analgesia. Statistical analysis included Student's <i>t</i>-test, Chi-square, and Z-test as appropriate, with statistical significance set at <i>P</i> < 0.05.</p><p><strong>Results: </strong>Group P demonstrated significantly higher quadriceps-muscle strength at 24 h (<i>P</i> = 0.025) and 48 h (<i>P</i> = 0.002) post surgery. More patients in Group P achieved superior weight-bearing grades at 24 h (<i>P</i> = 0.002) post surgery compared to Group S. VAS scores were significantly lower in Group P at 24 h post surgery (<i>P</i> = 0.006). Group P also showed a prolonged duration of analgesia (<i>P</i> = 0.019) and lower mean opioid consumption (<i>P</i> = 0.001) compared to Group S.</p><p><strong>Conclusion: </strong>The PENG block may be superior to the SIFI block in terms of functional outcomes with better quadriceps strength, enhanced weight-bearing, and provision of more effective postoperative analgesia in hip surgery patients.</p>","PeriodicalId":13339,"journal":{"name":"Indian Journal of Anaesthesia","volume":"68 12","pages":"1043-1048"},"PeriodicalIF":2.9,"publicationDate":"2024-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11812504/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143407407","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}