Yasmeen Jabeen Bhat, Mohd Shurjeel Ul Islam, Enzo Errichetti
{"title":"Ultraviolet-Induced Fluorescence Dermoscopy, a Novel Diagnostic Technique in Dermatological Practice: A Systematic Review.","authors":"Yasmeen Jabeen Bhat, Mohd Shurjeel Ul Islam, Enzo Errichetti","doi":"10.4103/idoj.idoj_299_24","DOIUrl":"10.4103/idoj.idoj_299_24","url":null,"abstract":"<p><strong>Introduction: </strong>Ultraviolet-induced fluorescence dermoscopy (UVF dermoscopy) is a novel diagnostic technique for identifying and diagnosing numerous skin tumors, inflammatory dermatoses, and infectious diseases. The ultraviolet (UV) band has a wavelength ranging from 10 to 400 nm. When intense UV radiation with shorter wavelengths strikes a target chromophore, visible light (VL) with a longer wavelength and lower energy is produced in the skin. This VL is apparent to the naked eye and is referred to as fluorescence.</p><p><strong>Aim: </strong>The current review compares ultraviolet fluorescence dermoscopy (UVFD) and polarized dermoscopy (PD) features in various dermatological disorders.</p><p><strong>Materials and methods: </strong>This review was performed in accordance with PRISMA (Preferred Reporting Items for Systematic Reviews and Metanalyses) guidelines. A comprehensive search of the literature was carried out through the PubMed and Google Scholar electronic databases from inception to 25<sup>th</sup> December 2023 using the following search terms: \"UV dermoscopy\" OR \"ultraviolet fluorescence dermoscopy\" OR \"ultraviolet-induced fluorescence dermoscopy\" OR \"Ultraviolet-induced fluorescent dermoscopy\". Titles, abstracts, and full texts were screened by two independent reviewers to select papers dealing with UVF-dermoscopy.</p><p><strong>Results: </strong>A total of 23 relevant articles were included in this systematic review, including a total of 313 patients. Pigmented skin tumors included 209 patients, Fordyce spot mimickers (13), scabies (57), biopsy site (20), psoriasis (3), corynebacterium infections (2), fungal infections (4), vitiligo (3), acne folliculitis (1) and glomus tumors (1). Levels of evidence (LoE) was 3 and 4 in only two included studies; the rest had a LoE of 5.</p><p><strong>Discussion: </strong>UVF dermoscopy is a new diagnostic and prognostic tool for neoplastic and non-neoplastic dermatological conditions. This is the first systematic review of its sort that compares and categorizes dermoscopic findings in UVF and polarized light in dermatological practice. As UVFD does not penetrate deeper skin layers, we observed that it is a better way to distinguish features restricted to the skin's superficial layers in neoplastic diseases. As a result, tumor-free margins and improved surgical outcomes can be achieved. More favorable outcomes for evaluation and treatment were seen with non-neoplastic conditions. Limitations included a lack of studies with a high level of evidence, control groups, and larger sample sizes.</p><p><strong>Conclusion: </strong>We concluded that UVFD will improve clinical diagnosis, disease management, and outcomes. More clinical trials with larger sample sizes are recommended to better understand this novel and intriguing new diagnostic tool.</p>","PeriodicalId":13335,"journal":{"name":"Indian Dermatology Online Journal","volume":"16 1","pages":"25-39"},"PeriodicalIF":1.9,"publicationDate":"2024-12-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11753565/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143028764","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Ramith P Shetty, M Ramesh Bhat, Myfanwy Joanne Dsouza, Michelle S Fernandes
{"title":"Unsuspecting Plaque on the Forearm: A Diagnostic Challenge.","authors":"Ramith P Shetty, M Ramesh Bhat, Myfanwy Joanne Dsouza, Michelle S Fernandes","doi":"10.4103/idoj.idoj_478_24","DOIUrl":"10.4103/idoj.idoj_478_24","url":null,"abstract":"<p><p>Microcystic adnexal carcinoma (MAC) is a rare, slow-growing, locally aggressive malignant, and recurring appendageal tumor. Prolonged UV exposure, immunosuppression, and radiotherapy are a few frequently associated risk factors. MAC classically presents as an asymptomatic skin coloured plaque on the face. The key to diagnosis is a deep-sectioned biopsy. Surgical modalities are the first line of treatment.</p>","PeriodicalId":13335,"journal":{"name":"Indian Dermatology Online Journal","volume":"16 1","pages":"137-140"},"PeriodicalIF":1.9,"publicationDate":"2024-12-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11753555/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143028765","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
M Thanoj K Reddy, Seetharam A Kolalapudi, Seva Praveen, Subhashini Konala, Gunnam L Rasajna, Saloni S Khutate
{"title":"Clinical and Laboratory Parameters of Metabolic Syndrome in Chronic Spontaneous Urticaria: A Cross-Sectional Study.","authors":"M Thanoj K Reddy, Seetharam A Kolalapudi, Seva Praveen, Subhashini Konala, Gunnam L Rasajna, Saloni S Khutate","doi":"10.4103/idoj.idoj_945_24","DOIUrl":"10.4103/idoj.idoj_945_24","url":null,"abstract":"<p><strong>Background: </strong>Chronic spontaneous urticaria (CSU) appears to share some pathomechanisms with metabolic syndrome (MS), such as proinflammatory state, increased oxidative stress, changes in adipokine profile, and coagulation system activation.</p><p><strong>Aim and objectives: </strong>To evaluate clinical and laboratory parameters of MS in CSU patients and to assess relationship of MS with duration and severity of CSU, Ig-E, thyroid-stimulating hormone (TSH), C-reactive protein (CRP), and autologous serum skin test (ASST).</p><p><strong>Materials and methods: </strong>A hospital-based cross-sectional study was conducted on 131 CSU cases and 131 controls who were age- and sex-matched. Duration of the CSU and urticaria activity score (UAS) were noted. Waist circumference (WC), blood pressure, fasting blood sugar, high-density lipoprotein (HDL), triglycerides (TG), CRP, TSH, IgE, and ASST were noted. MS was considered according to Harmonization Asian criteria.</p><p><strong>Results: </strong>The percentage of patients with elevated clinical and laboratory parameters of MS was higher in cases compared to controls, in which WC, HDL, and TG were significantly elevated. MS was positive in 25.19% and 14.50% of cases and controls, respectively (<i>P</i> = 0.044). Cases with MS had a significant higher mean duration (16.60 months) than those without MS (8.81 months) (<i>P</i> = 0.004). MS was positive in 15.2%, 32.3%, and 36.4% of mild, moderate, and severe UAS patients, respectively (<i>P</i> = 0.095). Patients with increased TSH and CRP had a significantly higher percentage of MS (68.4% and 40.7%, respectively) than with normal TSH and CRP (15% and 19.4%, respectively) (<i>P</i> < 0.05), while it was not significant with respect to IgE and ASST.</p><p><strong>Limitations: </strong>Small sample size and it was a hospital-based study, therefore, all controls were from the patients attending our outpatient department only and could not be compared with the general population.</p><p><strong>Conclusion: </strong>MS is not uncommon in CSU patients. The duration of CSU, CRP levels, and TSH levels have a significant positive correlation with MS. Screening, along with regular surveillance of CSU patients, aids in the early detection of MS and minimizes the risk of cardiovascular disease.</p>","PeriodicalId":13335,"journal":{"name":"Indian Dermatology Online Journal","volume":"16 1","pages":"105-109"},"PeriodicalIF":1.9,"publicationDate":"2024-12-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11753540/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143028743","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"A Survey on Quality of Services, Training, and Attitude of Dermatology Trainee Residents About Sexually Transmitted Infections in Teaching Hospitals Across India.","authors":"Nikhil Mehta, Sushant Agrawal, Japnoor Kaur, Somesh Gupta","doi":"10.4103/idoj.idoj_66_24","DOIUrl":"10.4103/idoj.idoj_66_24","url":null,"abstract":"<p><strong>Introduction: </strong>The incidence of sexually transmitted infections (STIs) has increased disproportionately to STI services. It is uncertain how many residents trained in STI services continue them. This study assessed the self-rated quality of training and attitudes about STI services amongst residents of Indian teaching hospitals.</p><p><strong>Materials and methods: </strong>In this descriptive cross-sectional survey study, opinions from Indian postgraduate trainee residents were sought in three domains of STIs- institutional STI management practices, quality and satisfaction with training, and attitude towards STI services.</p><p><strong>Results: </strong>A total of 225 responses were included. There was no separate area for STI services at centers of 51.6% of residents, and among those with separate STI posting, the duration was ≤2 months for 34.7%, with 59.6% wishing for its increase. Easily available bedside tests were used regularly when indicated by only 41.8%. Only 58.2% of respondents strictly ensured contact tracing and partner treatment. Only 65.8% of centers had provision of benzathine penicillin. Under-confidence in managing STIs independently was reported by 19.6%. Inadequate training was the second reason for wishing to discontinue STI services upon completion of training; with 71.5% wishing to continue STI practice. In univariate analysis, frequent point-of-care testing (<i>P</i> < 0.001), and >2 months of separate STI posting (<i>P</i> = 0.018) were associated with good satisfaction with STI training. Frequent point-of-care testing (<i>P</i> < 0.001), and male gender (<i>P</i> < 0.001) were associated with good confidence in independently managing STIs. Male gender (<i>P</i> = 0.038), having less reluctance in dealing with STI patients (<i>P</i> = 0.003), and good confidence in independently managing STIs (<i>P</i> = 0.008), was associated with willingness to continue STI practice.</p><p><strong>Conclusions: </strong>STI care is associated with reluctance. Current STI training in Indian teaching hospitals is less than desired and can lead to unwillingness amongst residents to practice STI services in the future. Having >2 months of separate STI posting, frequent point-of-care tests, and efforts to reduce reluctance when dealing with STI patients are steps that can improve the STI training experience of residents.</p>","PeriodicalId":13335,"journal":{"name":"Indian Dermatology Online Journal","volume":"16 1","pages":"94-104"},"PeriodicalIF":1.9,"publicationDate":"2024-12-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11753568/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143028680","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Nikhil Mehta, Binod K Khaitan, M Ramam, Neetu Bhari, Gomathy Sethuraman, Manoj K Singh
{"title":"Clinical and Histopathological Characteristics of Acquired Inflammatory Blaschko-Linear Disorders.","authors":"Nikhil Mehta, Binod K Khaitan, M Ramam, Neetu Bhari, Gomathy Sethuraman, Manoj K Singh","doi":"10.4103/idoj.idoj_312_24","DOIUrl":"10.4103/idoj.idoj_312_24","url":null,"abstract":"<p><strong>Introduction: </strong>Acquired inflammatory Blaschko-linear dermatoses have not been studied extensively. Descriptive studies on segmental vitiligo have yielded insights helpful in counseling patients. Similar insights are expected from studies on other acquired inflammatory Blaschko-linear diseases.</p><p><strong>Materials and methods: </strong>Consecutive patients with an acquired inflammatory Blaschko-linear disease presenting to the dermatology outpatient department of the study center were recruited in a case series. Detailed history and examination, clinical photographs, and histopathological findings were recorded and analyzed. Features were compared between linear and generalized forms to look for any differences.</p><p><strong>Results: </strong>Out of 99 patients, linear lichen planus (<i>n</i> = 47), linear morphea (<i>n</i> = 31), and lichen striatus (<i>n</i> = 9) were observed most commonly. Skin lesions were present in multiple lines in 52 (52.5%). In 12 (12.1%), more than one anatomical site was involved. In 10 (10.1%), two different Blaschko-linear diseases were seen, and in 3 (3.1%) both diseases occurred in the same/adjacent segments. The disease extended from one or both ends in 64 (88.9%). Nineteen (19.2%) had both linear and generalized disease, with linear lesions being more severe than the generalized lesions (<i>P</i> = 0.038133). Some (18/47, 38.3%) linear lichen planus cases showed prominent atrophy since the onset and formed a distinct subset, predominantly over the head and neck site (<i>P</i> < 0.00001). Histopathology of linear lichen planus differed from controls with generalized lesions in terms of having deeper infiltrate (<i>P</i> = 0.000124), and multi-focal, rather than confluent, lichenoid infiltrates. Atrophy was noted from the onset in 13/31 (41.9%) cases of linear morphea.</p><p><strong>Limitations: </strong>Limitations include cross-sectional design and lack of controls with generalized nonlinear diseases.</p><p><strong>Conclusions: </strong>Acquired inflammatory Blaschko-linear disorders show distinct characteristics like involvement of multiple lines and sites, directional progression, and atrophic variants. These can be used for differentiating among different Blaschko-linear diseases, monitoring progression, and counseling patients.</p>","PeriodicalId":13335,"journal":{"name":"Indian Dermatology Online Journal","volume":"16 1","pages":"116-122"},"PeriodicalIF":1.9,"publicationDate":"2024-12-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11753551/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143028742","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"High-Resolution Ultrasound in Evaluation of Peripheral Neuropathy in Patients of Hansen's Disease.","authors":"Mahmood D Al-Mendalawi","doi":"10.4103/idoj.idoj_464_24","DOIUrl":"10.4103/idoj.idoj_464_24","url":null,"abstract":"","PeriodicalId":13335,"journal":{"name":"Indian Dermatology Online Journal","volume":"16 1","pages":"195"},"PeriodicalIF":1.9,"publicationDate":"2024-12-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11753557/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143028752","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Ionized Plasma Jet Therapy in Removal of Dermatosis Papulosa Nigra.","authors":"Ajay Dodeja, Manjiri Oke, Milind Borkar, Shreyaa Mandawgade, Mallika Thobde","doi":"10.4103/idoj.idoj_524_24","DOIUrl":"10.4103/idoj.idoj_524_24","url":null,"abstract":"<p><strong>Background: </strong>Dermatosis papulosa nigra (DPN) presents as benign skin growths, predominantly affecting women and often commencing during adolescence. Treatment is sought due to its cosmetic impact, with available modalities often posing risks of scarring and pigmentary changes.</p><p><strong>Materials & methods: </strong>This study investigates the efficacy of ionized plasma jet therapy (IPJT) in ten DPN patients at a tertiary care hospital in central India. Patients underwent IPJT sessions, along with serial evaluations assessing pain, erythema, pigmentary changes, and lesion clearance.</p><p><strong>Results: </strong>Results showed 80% lesion clearance after the first session, with mild adverse effects such as erythema (40%), post inflammatory hyperpigmentation (20%), and hypopigmentation (10%) after 4 weeks.</p><p><strong>Conclusion: </strong>IPJT, utilizing ionized plasma, has shown success in various dermatological applications. The study underscores IPJT as a suitable treatment modality.</p>","PeriodicalId":13335,"journal":{"name":"Indian Dermatology Online Journal","volume":"16 1","pages":"129-131"},"PeriodicalIF":1.9,"publicationDate":"2024-12-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11753569/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143028755","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Persistence of Bacteriological Index After 1 Year of Multidrug Therapy Intake in Hansen's Patients: An Indication to Strengthen the Antimicrobial Surveillance.","authors":"Abhipsa Samal, Bhabani S T P Singh, Bikash R Kar","doi":"10.4103/idoj.idoj_783_23","DOIUrl":"10.4103/idoj.idoj_783_23","url":null,"abstract":"","PeriodicalId":13335,"journal":{"name":"Indian Dermatology Online Journal","volume":"16 1","pages":"186-188"},"PeriodicalIF":1.9,"publicationDate":"2024-12-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11753533/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143028758","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}