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Indian Dermatology Online Journal最新文献

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Efficacy and Safety of Injection Secukinumab in Patients of Pediatric Erythrodermic Psoriasis. 注射Secukinumab治疗小儿红皮病型银屑病的疗效和安全性。
IF 2
Indian Dermatology Online Journal Pub Date : 2026-09-01 Epub Date: 2026-03-18 DOI: 10.4103/idoj.idoj_388_25
Tanisha Nayak, Nibedita Dixit, Anil K Panda, Maitreyee Panda
{"title":"Efficacy and Safety of Injection Secukinumab in Patients of Pediatric Erythrodermic Psoriasis.","authors":"Tanisha Nayak, Nibedita Dixit, Anil K Panda, Maitreyee Panda","doi":"10.4103/idoj.idoj_388_25","DOIUrl":"10.4103/idoj.idoj_388_25","url":null,"abstract":"","PeriodicalId":13335,"journal":{"name":"Indian Dermatology Online Journal","volume":" ","pages":"705-707"},"PeriodicalIF":2.0,"publicationDate":"2026-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13588460/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147473553","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Lichen Planus Pemphigoides in Childhood. 儿童期类天疱疮扁平苔藓。
IF 2
Indian Dermatology Online Journal Pub Date : 2026-09-01 Epub Date: 2026-06-08 DOI: 10.4103/idoj.idoj_176_25
Harshitha Srinivasan, Amuthavalli Kanagarajan, Reena Rai, Sakthisankari Shanmugasundaram
{"title":"Lichen Planus Pemphigoides in Childhood.","authors":"Harshitha Srinivasan, Amuthavalli Kanagarajan, Reena Rai, Sakthisankari Shanmugasundaram","doi":"10.4103/idoj.idoj_176_25","DOIUrl":"10.4103/idoj.idoj_176_25","url":null,"abstract":"","PeriodicalId":13335,"journal":{"name":"Indian Dermatology Online Journal","volume":" ","pages":"696-699"},"PeriodicalIF":2.0,"publicationDate":"2026-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13588448/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148204745","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Porokeratotic Eccrine Ostial and Dermal Duct Nevus: Utility of Ultraviolet-Induced Fluorescence Dermoscopy Findings in a Rare Presentation. 微角化性内分泌口及真皮导管痣：紫外线诱导荧光皮肤镜检查结果的应用。
IF 2
Indian Dermatology Online Journal Pub Date : 2026-09-01 Epub Date: 2026-02-20 DOI: 10.4103/idoj.idoj_734_25
Payal Chauhan, Ria Sharma, Dilip Meena, Yashshavani Dass
{"title":"Porokeratotic Eccrine Ostial and Dermal Duct Nevus: Utility of Ultraviolet-Induced Fluorescence Dermoscopy Findings in a Rare Presentation.","authors":"Payal Chauhan, Ria Sharma, Dilip Meena, Yashshavani Dass","doi":"10.4103/idoj.idoj_734_25","DOIUrl":"10.4103/idoj.idoj_734_25","url":null,"abstract":"","PeriodicalId":13335,"journal":{"name":"Indian Dermatology Online Journal","volume":" ","pages":"741-742"},"PeriodicalIF":2.0,"publicationDate":"2026-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13588433/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"146257976","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Oral Tofacitinib for Refractory Lichen Planus Pigmentosus Coexisting with Frontal Fibrosing Alopecia. 口服托法替尼治疗顽固性扁平苔藓伴额部纤维化性脱发。
IF 2
Indian Dermatology Online Journal Pub Date : 2026-09-01 Epub Date: 2026-02-18 DOI: 10.4103/idoj.idoj_515_25
Surabhi Sinha, Kabir Sardana
{"title":"Oral Tofacitinib for Refractory Lichen Planus Pigmentosus Coexisting with Frontal Fibrosing Alopecia.","authors":"Surabhi Sinha, Kabir Sardana","doi":"10.4103/idoj.idoj_515_25","DOIUrl":"10.4103/idoj.idoj_515_25","url":null,"abstract":"","PeriodicalId":13335,"journal":{"name":"Indian Dermatology Online Journal","volume":" ","pages":"716-718"},"PeriodicalIF":2.0,"publicationDate":"2026-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13588425/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"146219596","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Gene Expression of Suppressor of Cytokine Signaling 3 (SOCS3), Interferons Alpha and Beta (IFN-α and β) in Common Warts. 细胞因子信号传导抑制因子3 （SOCS3）、干扰素α和β （IFN-α和β）在常见疣中的基因表达
IF 2
Indian Dermatology Online Journal Pub Date : 2026-09-01 Epub Date: 2026-08-26 DOI: 10.4103/idoj.idoj_893_25
Zeinab Abu El Baha Gouda, Hanan A Assaf, Noha Saber Shafik Amin, Reham Helal Abu Elhamd, Mohammed Abu El-Hamd
{"title":"Gene Expression of Suppressor of Cytokine Signaling 3 (SOCS3), Interferons Alpha and Beta (IFN-α and β) in Common Warts.","authors":"Zeinab Abu El Baha Gouda, Hanan A Assaf, Noha Saber Shafik Amin, Reham Helal Abu Elhamd, Mohammed Abu El-Hamd","doi":"10.4103/idoj.idoj_893_25","DOIUrl":"10.4103/idoj.idoj_893_25","url":null,"abstract":"<p><strong>Background: </strong>Cutaneous warts are benign epidermal growths caused by low-risk human papillomavirus. Interferon promotes an \"antiviral state\" in infected cells and neighboring cells through the activation of interferon-stimulated genes. The suppressor of cytokine signaling (SOCS) proteins bind to both Janus kinase and tyrosine kinase receptors, which further inhibit signal transducer and activator of transcription 3 phosphorylation.</p><p><strong>Aim and objectives: </strong>This study aimed to assess the tissue gene expression of SOCS3 and interferons alpha and beta ( IFN-α and β ) in common warts.</p><p><strong>Patients and methods: </strong>Forty patients with common warts, aged between 18 and 50 years, and 40 healthy controls were recruited. The gene expression of IFN-α, IFN-β, and SOCS3 by real-time reverse transcription polymerase chain reaction in the skin biopsies from the warts, normal skin of the patients, and healthy controls was estimated.</p><p><strong>Results: </strong>The median level of IFN-α was significantly higher in warts than non-lesional skin (20.8 vs 1) and both were significantly higher than that of control skin (0.7). The median level of IFN-β was significantly higher in warts than in non-lesional skin (20.7 vs 1.4) and both were significantly higher than that of control skin (1). The median level of SOCS3 was higher in nonlesional skin than in warts (1.05 vs 1), and both were significantly higher than that of control skin (0.1).</p><p><strong>Limitations: </strong>Small sample size.</p><p><strong>Conclusion: </strong>The expressions of IFN-α, IFN-β, and SOCS3 genes were significantly elevated in the lesional and nonlesional skin of patients with warts than in the control skin.</p>","PeriodicalId":13335,"journal":{"name":"Indian Dermatology Online Journal","volume":" ","pages":"668-674"},"PeriodicalIF":2.0,"publicationDate":"2026-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13588442/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148827895","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Scrotal Lepromatous Leprosy. 阴囊性麻风病。
IF 2
Indian Dermatology Online Journal Pub Date : 2026-09-01 Epub Date: 2026-04-30 DOI: 10.4103/idoj.idoj_807_25
Senkadhir Vendhan, Shekhar Neema, Santoshkumar Battula
{"title":"Scrotal Lepromatous Leprosy.","authors":"Senkadhir Vendhan, Shekhar Neema, Santoshkumar Battula","doi":"10.4103/idoj.idoj_807_25","DOIUrl":"10.4103/idoj.idoj_807_25","url":null,"abstract":"","PeriodicalId":13335,"journal":{"name":"Indian Dermatology Online Journal","volume":" ","pages":"756-757"},"PeriodicalIF":2.0,"publicationDate":"2026-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13588429/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147837580","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Assessment of Serum Survivin Levels as a Potential Biomarker for Disease Severity and Therapeutic Outcome: Results of a Pilot Study. 评估血清生存素水平作为疾病严重程度和治疗结果的潜在生物标志物：一项初步研究的结果。
IF 2
Indian Dermatology Online Journal Pub Date : 2026-09-01 Epub Date: 2026-08-24 DOI: 10.4103/idoj.idoj_1122_25
Kuruva Janakiramudu, Sumita Halder, Rajarshi Kar, Chander Grover, Rachna Gupta, Edelburt A Almeida
{"title":"Assessment of Serum Survivin Levels as a Potential Biomarker for Disease Severity and Therapeutic Outcome: Results of a Pilot Study.","authors":"Kuruva Janakiramudu, Sumita Halder, Rajarshi Kar, Chander Grover, Rachna Gupta, Edelburt A Almeida","doi":"10.4103/idoj.idoj_1122_25","DOIUrl":"10.4103/idoj.idoj_1122_25","url":null,"abstract":"<p><strong>Background: </strong>Psoriasis is a chronic inflammatory skin disease characterized by hyperproliferation of keratinocytes and immune dysregulation. Survivin, being an apoptosis inhibitor, could be a potential biomarker for psoriasis.</p><p><strong>Aim and objectives: </strong>To evaluate serum survivin levels in moderate to severe psoriasis patients before and after methotrexate therapy and to assess its correlation with disease severity using Psoriasis Area and Severity Index (PASI).</p><p><strong>Patients and methods: </strong>This study included 30 patients with moderate to severe psoriasis and 30 healthy controls. Serum survivin levels were measured at baseline and at 12 weeks of methotrexate therapy. Disease severity was assessed using PASI.</p><p><strong>Results: </strong>Serum survivin levels were considerably higher in psoriasis patients than in controls (70.3 ± 16.9 vs. 22.1 ± 9.4 pg/mL; P < 0.001). Following methotrexate therapy, serum survivin levels decreased (20.9 ± 8.0 pg/mL; P < 0.001) and PASI scores reduced in tandem from 15.3 ± 4.8 to 7.5 ± 4.4 ( P < 0.001). Improvement in PASI was significantly associated with survivin reduction (r = 0.672; P < 0.001).</p><p><strong>Limitations: </strong>Small sample size, short follow-up duration, and lack of histopathological assessment or tissue survivin evaluation. Additionally, the absence of long-term follow-up and potential noncompliance with smoking/alcohol abstinence may have influenced the findings.</p><p><strong>Conclusion: </strong>Serum survivin levels were significantly elevated in psoriasis patients compared to healthy controls and were reduced significantly following treatment with methotrexate. These changes in serum survivin levels corresponded well with decreasing PASI scores in psoriasis patients, suggesting survivin as a potential biomarker of disease activity and therapeutic response.</p>","PeriodicalId":13335,"journal":{"name":"Indian Dermatology Online Journal","volume":"17 5","pages":"688-692"},"PeriodicalIF":2.0,"publicationDate":"2026-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13588454/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148863853","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Gorlin-Goltz Syndrome in an Elderly Patient: Clinical Presentation and Diagnosis. 老年患者Gorlin-Goltz综合征的临床表现和诊断。
IF 2
Indian Dermatology Online Journal Pub Date : 2026-09-01 Epub Date: 2026-08-26 DOI: 10.4103/idoj.idoj_1157_25
Ruchika A Nevse, Arjun Prakashey, Sushil Pande
{"title":"Gorlin-Goltz Syndrome in an Elderly Patient: Clinical Presentation and Diagnosis.","authors":"Ruchika A Nevse, Arjun Prakashey, Sushil Pande","doi":"10.4103/idoj.idoj_1157_25","DOIUrl":"10.4103/idoj.idoj_1157_25","url":null,"abstract":"","PeriodicalId":13335,"journal":{"name":"Indian Dermatology Online Journal","volume":" ","pages":"764-766"},"PeriodicalIF":2.0,"publicationDate":"2026-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13588452/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148827980","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
A Pink Dome on the Digit: Diagnostic Clues to a Digital Myxoid Cyst. 手指上的粉色圆顶：指黏液样囊肿的诊断线索。
IF 2
Indian Dermatology Online Journal Pub Date : 2026-09-01 Epub Date: 2026-05-26 DOI: 10.4103/idoj.idoj_1042_25
Chitwan Kaur Ghuman, Veeranna Shastry
{"title":"A Pink Dome on the Digit: Diagnostic Clues to a Digital Myxoid Cyst.","authors":"Chitwan Kaur Ghuman, Veeranna Shastry","doi":"10.4103/idoj.idoj_1042_25","DOIUrl":"10.4103/idoj.idoj_1042_25","url":null,"abstract":"","PeriodicalId":13335,"journal":{"name":"Indian Dermatology Online Journal","volume":" ","pages":"760-761"},"PeriodicalIF":2.0,"publicationDate":"2026-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13588444/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148163127","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Linear Bulla with Surface Corrugations: Novel Dermoscopy Features in Bullous Cutaneous Larva Migrans. 具有表面波纹的线性大疱：大疱性皮肤幼虫迁移的新皮肤镜特征。
IF 2
Indian Dermatology Online Journal Pub Date : 2026-09-01 Epub Date: 2026-08-26 DOI: 10.4103/idoj.idoj_1138_25
Aradhana Rout, Vikas Pathania, Siddharth Mani
{"title":"Linear Bulla with Surface Corrugations: Novel Dermoscopy Features in Bullous Cutaneous Larva Migrans.","authors":"Aradhana Rout, Vikas Pathania, Siddharth Mani","doi":"10.4103/idoj.idoj_1138_25","DOIUrl":"10.4103/idoj.idoj_1138_25","url":null,"abstract":"","PeriodicalId":13335,"journal":{"name":"Indian Dermatology Online Journal","volume":" ","pages":"767-768"},"PeriodicalIF":2.0,"publicationDate":"2026-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13588446/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148827985","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
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