Indian Dermatology Online Journal最新文献

{"title":"Extensive Nevus Comedonicus Along the Lines of Blaschko - Through the Eyes of Dermoscope and Histopathology.","authors":"Trishala Shirahatti","doi":"10.4103/idoj.idoj_287_24","DOIUrl":"10.4103/idoj.idoj_287_24","url":null,"abstract":"","PeriodicalId":13335,"journal":{"name":"Indian Dermatology Online Journal","volume":"16 3","pages":"521-522"},"PeriodicalIF":1.9,"publicationDate":"2025-01-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12088475/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144110585","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Atrophic Variant of Dermatofibrosarcoma Protuberans Masquerading as an Alopecic Patch on the Beard.","authors":"Aditi Shende, Farida Kapadia, Radha Mundhra, Smita Ghate","doi":"10.4103/idoj.idoj_893_23","DOIUrl":"10.4103/idoj.idoj_893_23","url":null,"abstract":"","PeriodicalId":13335,"journal":{"name":"Indian Dermatology Online Journal","volume":"16 2","pages":"335-337"},"PeriodicalIF":1.9,"publicationDate":"2025-01-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11927992/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143692177","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Prolonged Blistering Following Erythema Multiforme Major in a Child with COVID-19: A Twist in the Tale.","authors":"Chandana Shajil, Lydia Mathew, Dharshini Sathishkumar, Ramesh Babu Telugu","doi":"10.4103/idoj.idoj_146_24","DOIUrl":"10.4103/idoj.idoj_146_24","url":null,"abstract":"","PeriodicalId":13335,"journal":{"name":"Indian Dermatology Online Journal","volume":"16 2","pages":"332-334"},"PeriodicalIF":1.9,"publicationDate":"2025-01-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11927998/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143691959","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Cutaneous Involvement in a Case of T-lymphoblastic Lymphoma: A Rare Presentation.","authors":"Priyanka Kowe, Madhusmita Sethy, Biswanath Behera, Pritinanda Mishra, Ashutosh Panigrahi","doi":"10.4103/idoj.idoj_20_24","DOIUrl":"10.4103/idoj.idoj_20_24","url":null,"abstract":"","PeriodicalId":13335,"journal":{"name":"Indian Dermatology Online Journal","volume":"16 2","pages":"326-329"},"PeriodicalIF":1.9,"publicationDate":"2025-01-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11927966/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143692140","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Decoding the Lichenoid Riddle of Red Tattoos.","authors":"Rohan Manoj, Aditi Gupta, Aayush Gupta","doi":"10.4103/idoj.idoj_109_24","DOIUrl":"10.4103/idoj.idoj_109_24","url":null,"abstract":"","PeriodicalId":13335,"journal":{"name":"Indian Dermatology Online Journal","volume":"16 3","pages":"493-495"},"PeriodicalIF":1.9,"publicationDate":"2025-01-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12088467/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144110569","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"A Farewell Note with Parting Reflections.","authors":"K A Seetharam","doi":"10.4103/idoj.idoj_1211_24","DOIUrl":"https://doi.org/10.4103/idoj.idoj_1211_24","url":null,"abstract":"","PeriodicalId":13335,"journal":{"name":"Indian Dermatology Online Journal","volume":"16 1","pages":"1-2"},"PeriodicalIF":1.9,"publicationDate":"2024-12-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11753573/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143028674","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Laser Treatment in Nail Disorders: A Comprehensive Review.","authors":"Byalakere Shivanna Chandrashekar, Chandu Madura, Chaitra Shenoy, Abhijna Chandar, Mysore Seshadri Roopa, Nakka Lakshmi Narayana","doi":"10.4103/idoj.idoj_776_24","DOIUrl":"10.4103/idoj.idoj_776_24","url":null,"abstract":"<p><strong>Background: </strong>Laser therapy has emerged as an innovative approach for managing various nail conditions, offering precise targeting, minimal invasiveness, and favorable safety profiles. This review analyzes the literature on laser therapy for nail indications, encompassing onychomycosis, nail psoriasis, nail warts, ingrown toenails, onychodystrophy, nail pigmentation disorders, and nail tumors.</p><p><strong>Methods: </strong>PubMed and Google Scholar databases were searched to identify articles on laser therapy using specific key terms related to nail conditions (e.g., onychomycosis, nail psoriasis). Relevant articles were shortlisted based on laser treatment in nail disorders, its mechanisms of action, research outcomes, and clinical applications.</p><p><strong>Results: </strong>Nd: YAG or CO₂ lasers showed efficacy in onychomycosis by targeting fungal cells. Studies suggest that laser treatments offer comparable results to traditional therapies, often enhancing outcomes when combined with topical agents such as calcipotriol/betamethasone in nail psoriasis. For nail warts, ingrown toenails, onychodystrophy, and nail pigmentation disorders, lasers provide alternative or adjunctive therapies, achieving positive outcomes lesion clearance and symptom improvement. Conclusion: This review underscores the transformative potential of laser therapy in nail disorder management, providing clinicians with innovative treatment alternatives. Nevertheless, further studies are needed to refine protocols, evaluate long-term outcomes and explore its application in specific conditions such as nail tumors.</p>","PeriodicalId":13335,"journal":{"name":"Indian Dermatology Online Journal","volume":"16 1","pages":"59-71"},"PeriodicalIF":1.9,"publicationDate":"2024-12-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11753577/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143028756","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Antifungal Susceptibility of Dermatophyte Isolates from Patients with Chronic and Recurrent Dermatophytosis.","authors":"Nikhitha Amin, Manjunath M Shenoy, Vidya Pai","doi":"10.4103/idoj.idoj_192_24","DOIUrl":"10.4103/idoj.idoj_192_24","url":null,"abstract":"<p><strong>Background: </strong>The widespread occurrence of chronic and recurrent dermatophytosis has significantly affected the quality of life for patients in India and beyond. Identifying the causative dermatophytes and understanding their antifungal susceptibility can aid clinicians in tailoring effective antifungal therapies.</p><p><strong>Materials and methods: </strong>Patients with chronic and recurrent dermatophytosis were enrolled, and conventional fungal cultures were conducted on skin scrapings. Identified isolates underwent antifungal susceptibility testing using the Clinical and Laboratory Standards Institute broth microdilution method (CLSI M38-A2) for common systemic antifungals, determining the minimum inhibitory concentration (MIC) range and calculating MIC 50 and MIC 90.</p><p><strong>Results: </strong>Sixty samples were tested. Tinea corporis was the most common presentation (66.6%). <i>Trichophyton mentagrophyte</i> species complex was the prevalent species (45, 75%), followed by <i>Trichophyton rubrum</i> (7, 11.7%). In <i>Trichophyton mentagrophytes</i> species complex, MIC range was 8-64 μg/mL for fluconazole, 0.06-0.25 μg/mL for terbinafine, and 0.125-0.5 μg/mL for griseofulvin. For <i>Trichophyton rubrum</i>, the MIC range was 8-64 μg/mL for fluconazole, 0.06-0.25 μg/mL for terbinafine, and 0.125-0.5 μg/mL for griseofulvin. For all species, itraconazole MIC was ≤0.125 μg/mL. Hence, itraconazole and terbinafine had the best MIC range against tested isolates in our study.</p><p><strong>Limitations: </strong>Absence of genotyping of isolate and not compared the results with studies where sequence-based identification to species level was done.</p><p><strong>Conclusion: </strong><i>In vitro</i>, resistance to itraconazole for any of the four isolated agents was not seen. Terbinafine resistance appears to be an uncommon occurrence in South India. <i>In vitro</i> susceptibility tests shall be regularly done to design the epidemiological cutoff values.</p>","PeriodicalId":13335,"journal":{"name":"Indian Dermatology Online Journal","volume":"16 1","pages":"110-115"},"PeriodicalIF":1.9,"publicationDate":"2024-12-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11753564/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143028684","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Biologics and Small Molecules for Inflammatory Nail Disorders: A Narrative Review.","authors":"Carrie A Forman, Shari R Lipner","doi":"10.4103/idoj.idoj_445_24","DOIUrl":"10.4103/idoj.idoj_445_24","url":null,"abstract":"<p><strong>Background: </strong>Inflammatory dermatological conditions, including psoriasis, lichen planus, eczema, and alopecia areata, are frequently accompanied by nail findings and can have a significant impact on quality of life. Biologic and small-molecule medications have been approved over the past several decades in treating patients with these inflammatory nail disorders. They may be used in conjunction with longstanding mainstays of treatment (topical and intralesional corticosteroids, topical vitamin D3 analogs).</p><p><strong>Objectives: </strong>Our objectives were to review biologic and small-molecule treatment efficacies for nail psoriasis and alopecia areata-associated nail dystrophy, including Janus kinase inhibitors, apremilast, tumor necrosis factor (TNF) inhibitors, interleukin (IL)-17 inhibitors, and IL-23 inhibitors.</p><p><strong>Materials and methods: </strong>A comprehensive PubMed literature review of clinical research studies, narrative reviews, systematic reviews, and meta-analyses was performed.</p><p><strong>Conclusion: </strong>Many biologics and small molecules are effective in treating nail psoriasis and alopecia areata, with each requiring precautions for adverse events. Clinical trials for use of biologics and small molecules for nail lichen planus and atopic dermatitis have not been published to date.</p>","PeriodicalId":13335,"journal":{"name":"Indian Dermatology Online Journal","volume":"16 1","pages":"50-58"},"PeriodicalIF":1.9,"publicationDate":"2024-12-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11753575/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143028741","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Consensus Based Indian Guidelines for the Management of Pemphigus Vulgaris and Pemphigus Foliaceous.","authors":"Dipankar De, Hitaishi Mehta, Shikha Shah, Kidangazhiathmana Ajithkumar, Shyamanta Barua, Laxmisha Chandrashekar, Manas Chatterjee, Vishal Gupta, Sujay Khandpur, Geeti Khullar, Seetharam Anjaneyulu Kolalapudi, Sheetanshu Kumar, Shekhar Neema, Deepika Pandhi, Shital Poojary, Reena Rai, Murlidhar Rajagopalan, Raghavendra Rao, Bela Shah, Archana Singal, Vishal Thakur, Keshavamurthy Vinay, Ashutosh Aggrawal, Arka De, Soham Mukherjee, Shankar Prinja, Rahul Mahajan, Sanjeev Handa","doi":"10.4103/idoj.idoj_1059_24","DOIUrl":"10.4103/idoj.idoj_1059_24","url":null,"abstract":"<p><p>Pemphigus is an autoimmune blistering disorder characterized by the presence of intraepidermal blisters and erosions, primarily affecting the mucosa and/or skin. There are no established Indian guidelines for the management of pemphigus, and Western guidelines cannot be directly applied due to differences in clinicodemographic profiles, comorbidities, and resource limitations. These guidelines aim to provide Indian dermatologists with evidence-based and consensus-driven recommendations for the management of pemphigus vulgaris (PV) and pemphigus foliaceous (PF), taking into account the unique challenges posed by the Indian healthcare setting. The guidelines focus on the comprehensive management of PV and PF, addressing diagnosis, treatment, monitoring, and follow-up. It is intended for dermatologists working in both outpatient and inpatient settings across India. The first draft of the guidelines was prepared by the writing group and then reviewed by 19 national experts in pemphigus management, including inputs from allied specialties. Areas with limited evidence or anticipated variation in recommendations were subjected to rounds of voting, with responses categorized as \"strongly agree,\" \"agree,\" \"neutral,\" \"disagree,\" or \"strongly disagree.\" Suggestions were incorporated, and statements were revised until a mean agreement score of 4 or higher was reached across 16 key areas after four voting rounds. These guidelines offer a structured approach to managing pemphigus in India, addressing the need for region-specific recommendations that account for unique challenges such as resource constraints and specific comorbidities in Indian patients. They serve as a valuable resource for dermatologists treating pemphigus in a range of clinical settings.</p>","PeriodicalId":13335,"journal":{"name":"Indian Dermatology Online Journal","volume":"16 1","pages":"3-24"},"PeriodicalIF":1.9,"publicationDate":"2024-12-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11753534/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143028744","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}