Indian Dermatology Online Journal最新文献_第10页

Eruptive Hypomelanosis: The Ever-Evolving Story of Paraviral Exanthem 爆发性黑斑病：副病毒性皮疹不断演变的故事

IF 1.7

Indian Dermatology Online Journal Pub Date : 2024-05-20 DOI: 10.4103/idoj.idoj_753_23

Kusumika Kanak, S. Hegde, V. Sardesai

引用次数: 0

Abdominal Pseudo Hernia: A Rare Complication of Herpes Zoster 腹部假性疝：带状疱疹的罕见并发症

IF 1.7

Indian Dermatology Online Journal Pub Date : 2024-05-20 DOI: 10.4103/idoj.idoj_523_23

Riya Sukhija, Mitanjali Sethy, Chakravarthy R. Srinivas, Kriti Jain

引用次数: 0

Noonan Syndrome Like with Loose Anagen-1 due to SHOC2 Mutation—A Report of Two Cases from India 因 SHOC2 基因突变导致的努南综合征样 Anagen-1 松弛症--印度两例病例的报告

IF 1.7

Indian Dermatology Online Journal Pub Date : 2024-05-20 DOI: 10.4103/idoj.idoj_767_23

V.K. Gowda, Deepa B. Yalagishettar, Varunvenkat M Srinivasan, S. Srinivas

引用次数: 0

Clinico-Epidemiological Profile of Childhood Vitiligo 儿童白癜风的临床流行病学概况

IF 1.7

Indian Dermatology Online Journal Pub Date : 2024-05-20 DOI: 10.4103/idoj.idoj_533_23

Abhijit S. Chakraborty, Rashmi Agarwal, Pellakuru Preethi, B. Chandrashekar

引用次数: 0

Comparison of the Clinical Efficacy of Rituximab Infusion and Dexamethasone-Cyclophosphamide Pulse Therapy and Their Effect on Serum Th1, Th2, and Th17 Cytokines in Pemphigus Vulgaris-A Prospective, Nonrandomized, Comparative Pilot Study. 比较利妥昔单抗输注和地塞米松-环磷酰胺脉冲疗法的临床疗效及其对丘疹性天疱疮患者血清 Th1、Th2 和 Th17 细胞因子的影响--一项前瞻性、非随机、比较试验研究。

IF 1.7

Indian Dermatology Online Journal Pub Date : 2024-04-29 eCollection Date: 2024-05-01 DOI: 10.4103/idoj.idoj_558_23

Sujay Khandpur, Preeti Sharma, Vinod K Sharma, Dayasagar Das, Alpana Sharma, Neetu Bhari, Vishnubhatla Sreenivas

{"title":"Comparison of the Clinical Efficacy of Rituximab Infusion and Dexamethasone-Cyclophosphamide Pulse Therapy and Their Effect on Serum Th1, Th2, and Th17 Cytokines in Pemphigus Vulgaris-A Prospective, Nonrandomized, Comparative Pilot Study.","authors":"Sujay Khandpur, Preeti Sharma, Vinod K Sharma, Dayasagar Das, Alpana Sharma, Neetu Bhari, Vishnubhatla Sreenivas","doi":"10.4103/idoj.idoj_558_23","DOIUrl":"10.4103/idoj.idoj_558_23","url":null,"abstract":"Background: Rituximab infusion and dexamethasone-cyclophosphamide pulse (DCP) are the two most popular regimens used in pemphigus vulgaris (PV) in India.Objective: The present study compared the clinical efficacy of rituximab and DCP in Indian PV patients and their effects on serum Th1,2, and 17 cytokine levels.Materials and methods: A total of 37 patients received DCP (Group A, n = 22) or rituximab (Group B, rheumatoid arthritis protocol (n = 15)) as per patients' preference. They were monitored for clinical response, adverse events (AEs), changes in serum anti-desmoglein-1,3 antibody titers and Th1,2 and 17 cytokine levels at baseline and weeks 20 and 52.Results: The proportion of patients attaining disease control, remission, and relapse in groups A and B were 82% and 93%; 73% and 93%; and 27% and 50%, respectively, after a median duration of 2 months each for disease control; 4 and 4.5 months for remission; and 5 and 7 months for relapse post remission. The musculoskeletal AEs were the highest in the two groups. Significant and comparable decreases in anti-dsg1 and 3 titers from baseline to weeks 20 and 52 were observed in both groups. Th1 and Th17 cytokine levels decreased, while Th2 cytokines increased post-treatment in both groups. However, no correlation was found between change in body surface area of involvement by PV and anti-dsg titers and cytokine levels before and after therapy in both groups.Conclusion: Comparable clinical efficacy between DCP and rituximab was observed.","PeriodicalId":13335,"journal":{"name":"Indian Dermatology Online Journal","volume":null,"pages":null},"PeriodicalIF":1.7,"publicationDate":"2024-04-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11152478/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141283607","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Dermato-Radiological Evaluation of Congenital Limb Overgrowth Vascular Syndromes. 先天性肢体过度生长血管综合征的皮肤放射学评估。

IF 1.7

Indian Dermatology Online Journal Pub Date : 2024-04-29 eCollection Date: 2024-05-01 DOI: 10.4103/idoj.idoj_500_23

Suryansh Arora, Shibani Mehra, Ipshita Bhattacharya, Civilee Nanda

引用次数: 0

Erratum: High-Resolution Ultrasound in Evaluation of Peripheral Neuropathy in Patients of Hansen's Disease. 勘误：用高分辨率超声波评估汉森氏病患者的周围神经病变。

IF 1.7

Indian Dermatology Online Journal Pub Date : 2024-04-29 eCollection Date: 2024-05-01 DOI: 10.4103/idoj.idoj_368_24

引用次数: 0

Herpetic Syringitis-A Rare Presentation of Genital Herpes in an Immunocompetent Person. 疱疹性咽峡炎--免疫力低下者生殖器疱疹的罕见表现形式

IF 1.7

Indian Dermatology Online Journal Pub Date : 2024-04-29 eCollection Date: 2024-05-01 DOI: 10.4103/idoj.idoj_228_23

Preema Sinha, Sampoorna R Choudhary, Manoj G Madakshira, Parul Kamboj, G B Prashantha

引用次数: 0

RASopathies: Evolving Concepts in Pathogenetics, Clinical Features, and Management. RAS病：病因学、临床特征和管理方面不断演变的概念。

IF 1.7

Indian Dermatology Online Journal Pub Date : 2024-04-29 eCollection Date: 2024-05-01 DOI: 10.4103/idoj.idoj_594_23

Jigna Padhiyar, Rahul Mahajan, Maitreyee Panda

{"title":"RASopathies: Evolving Concepts in Pathogenetics, Clinical Features, and Management.","authors":"Jigna Padhiyar, Rahul Mahajan, Maitreyee Panda","doi":"10.4103/idoj.idoj_594_23","DOIUrl":"10.4103/idoj.idoj_594_23","url":null,"abstract":"RASopathies refers to the group of disorders which are caused by a mutation in various genes of the RAS/MAPK (RAT sarcoma virus/Mitogen activated protein kinase) pathway. It includes many genes with varied functions, which are responsible for cell cycle regulation. As the mutation in one gene affects the entire pathway, there are many overlapping features among the various syndromes which are included under an umbrella term \"RASopathies.\" However, neuroectodermal involvement is a unifying feature among these syndromes, which are caused by germline mutations affecting genes along this pathway. Recently, many other RASopathies have been described to involve blood vessels, lymphatics, and immune system. Also, many cutaneous mosaic disorders have been found to have mutations in the concerned pathway. The purpose of this article is to briefly review the pathogenesis of RASopathies with cutaneous manifestations, and summarise the features that can be helpful as diagnostic clues to dermatologists. As we understand more about the pathogenesis of the pathway at the cellular level, the research on genotype-phenotype correlation and therapeutic options broadens. Targeted therapy is in the clinical and preclinical trial phase, which may brighten the future of many patients.","PeriodicalId":13335,"journal":{"name":"Indian Dermatology Online Journal","volume":null,"pages":null},"PeriodicalIF":1.7,"publicationDate":"2024-04-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11152490/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141285842","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Quality of Life and Perceived Stress in Chronic Spontaneous Urticaria: Counting the Burden. 慢性自发性荨麻疹患者的生活质量和感知压力：计算负担。

IF 1.7

Indian Dermatology Online Journal Pub Date : 2024-04-29 eCollection Date: 2024-05-01 DOI: 10.4103/idoj.idoj_367_23

Jose Reeshma, Olasseri Kalathingal Reena Mariyath, Ktp Dayal Narayan, Keerankulangara Devi, Kidangazhiyathmana Ajithkumar

{"title":"Quality of Life and Perceived Stress in Chronic Spontaneous Urticaria: Counting the Burden.","authors":"Jose Reeshma, Olasseri Kalathingal Reena Mariyath, Ktp Dayal Narayan, Keerankulangara Devi, Kidangazhiyathmana Ajithkumar","doi":"10.4103/idoj.idoj_367_23","DOIUrl":"10.4103/idoj.idoj_367_23","url":null,"abstract":"Background: Chronic spontaneous urticaria (CSU) is a dermatosis with a significant psychological component. Only a few studies have assessed the quality of life (QoL) and perceived stress in CSU patients.Objectives: To evaluate the QoL and perceived stress in patients with CSU.Materials and methods: A cross-sectional study was done on 54 patients of CSU attending the Urticaria clinic of the Dermatology department in a tertiary care postgraduate teaching hospital in North Kerala. QoL in chronic urticaria was assessed using the Chronic Urticaria-Quality of Life (CU-QoL) questionnaire and perceived stress was assessed using the Perceived Stress Scale (PSS).Results: The mean scores of CU-QoL and PSS were 55.78 and 16.31, respectively. Out of 54 patients, 26 (48.1%) had mild impairment, 26 (48.1%) had moderate impairment, and 2 (3.7%) had severe impairment of QoL. Low stress was seen in 20 (37%) patients, moderate stress in 28 (51.9%), and six (11.1%) patients had high stress.Conclusion: This study shows that more than half of the patients with CSU had moderate to severe impairment of QoL and had moderate to severe stress.","PeriodicalId":13335,"journal":{"name":"Indian Dermatology Online Journal","volume":null,"pages":null},"PeriodicalIF":1.7,"publicationDate":"2024-04-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11152486/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141283619","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0