Indian Dermatology Online Journal最新文献

{"title":"Lichen Planus Pemphigoides in Childhood.","authors":"Harshitha Srinivasan, Amuthavalli Kanagarajan, Reena Rai, Sakthisankari Shanmugasundaram","doi":"10.4103/idoj.idoj_176_25","DOIUrl":"10.4103/idoj.idoj_176_25","url":null,"abstract":"","PeriodicalId":13335,"journal":{"name":"Indian Dermatology Online Journal","volume":" ","pages":"696-699"},"PeriodicalIF":2.0,"publicationDate":"2026-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13588448/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148204745","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Porokeratotic Eccrine Ostial and Dermal Duct Nevus: Utility of Ultraviolet-Induced Fluorescence Dermoscopy Findings in a Rare Presentation.","authors":"Payal Chauhan, Ria Sharma, Dilip Meena, Yashshavani Dass","doi":"10.4103/idoj.idoj_734_25","DOIUrl":"10.4103/idoj.idoj_734_25","url":null,"abstract":"","PeriodicalId":13335,"journal":{"name":"Indian Dermatology Online Journal","volume":" ","pages":"741-742"},"PeriodicalIF":2.0,"publicationDate":"2026-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13588433/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"146257976","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Oral Tofacitinib for Refractory Lichen Planus Pigmentosus Coexisting with Frontal Fibrosing Alopecia.","authors":"Surabhi Sinha, Kabir Sardana","doi":"10.4103/idoj.idoj_515_25","DOIUrl":"10.4103/idoj.idoj_515_25","url":null,"abstract":"","PeriodicalId":13335,"journal":{"name":"Indian Dermatology Online Journal","volume":" ","pages":"716-718"},"PeriodicalIF":2.0,"publicationDate":"2026-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13588425/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"146219596","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Gene Expression of Suppressor of Cytokine Signaling 3 (SOCS3), Interferons Alpha and Beta (IFN-α and β) in Common Warts.","authors":"Zeinab Abu El Baha Gouda, Hanan A Assaf, Noha Saber Shafik Amin, Reham Helal Abu Elhamd, Mohammed Abu El-Hamd","doi":"10.4103/idoj.idoj_893_25","DOIUrl":"10.4103/idoj.idoj_893_25","url":null,"abstract":"<p><strong>Background: </strong>Cutaneous warts are benign epidermal growths caused by low-risk human papillomavirus. Interferon promotes an \"antiviral state\" in infected cells and neighboring cells through the activation of interferon-stimulated genes. The suppressor of cytokine signaling (SOCS) proteins bind to both Janus kinase and tyrosine kinase receptors, which further inhibit signal transducer and activator of transcription 3 phosphorylation.</p><p><strong>Aim and objectives: </strong>This study aimed to assess the tissue gene expression of SOCS3 and interferons alpha and beta ( IFN-α and β ) in common warts.</p><p><strong>Patients and methods: </strong>Forty patients with common warts, aged between 18 and 50 years, and 40 healthy controls were recruited. The gene expression of IFN-α, IFN-β, and SOCS3 by real-time reverse transcription polymerase chain reaction in the skin biopsies from the warts, normal skin of the patients, and healthy controls was estimated.</p><p><strong>Results: </strong>The median level of IFN-α was significantly higher in warts than non-lesional skin (20.8 vs 1) and both were significantly higher than that of control skin (0.7). The median level of IFN-β was significantly higher in warts than in non-lesional skin (20.7 vs 1.4) and both were significantly higher than that of control skin (1). The median level of SOCS3 was higher in nonlesional skin than in warts (1.05 vs 1), and both were significantly higher than that of control skin (0.1).</p><p><strong>Limitations: </strong>Small sample size.</p><p><strong>Conclusion: </strong>The expressions of IFN-α, IFN-β, and SOCS3 genes were significantly elevated in the lesional and nonlesional skin of patients with warts than in the control skin.</p>","PeriodicalId":13335,"journal":{"name":"Indian Dermatology Online Journal","volume":" ","pages":"668-674"},"PeriodicalIF":2.0,"publicationDate":"2026-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13588442/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148827895","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Scrotal Lepromatous Leprosy.","authors":"Senkadhir Vendhan, Shekhar Neema, Santoshkumar Battula","doi":"10.4103/idoj.idoj_807_25","DOIUrl":"10.4103/idoj.idoj_807_25","url":null,"abstract":"","PeriodicalId":13335,"journal":{"name":"Indian Dermatology Online Journal","volume":" ","pages":"756-757"},"PeriodicalIF":2.0,"publicationDate":"2026-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13588429/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147837580","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Assessment of Serum Survivin Levels as a Potential Biomarker for Disease Severity and Therapeutic Outcome: Results of a Pilot Study.","authors":"Kuruva Janakiramudu, Sumita Halder, Rajarshi Kar, Chander Grover, Rachna Gupta, Edelburt A Almeida","doi":"10.4103/idoj.idoj_1122_25","DOIUrl":"10.4103/idoj.idoj_1122_25","url":null,"abstract":"<p><strong>Background: </strong>Psoriasis is a chronic inflammatory skin disease characterized by hyperproliferation of keratinocytes and immune dysregulation. Survivin, being an apoptosis inhibitor, could be a potential biomarker for psoriasis.</p><p><strong>Aim and objectives: </strong>To evaluate serum survivin levels in moderate to severe psoriasis patients before and after methotrexate therapy and to assess its correlation with disease severity using Psoriasis Area and Severity Index (PASI).</p><p><strong>Patients and methods: </strong>This study included 30 patients with moderate to severe psoriasis and 30 healthy controls. Serum survivin levels were measured at baseline and at 12 weeks of methotrexate therapy. Disease severity was assessed using PASI.</p><p><strong>Results: </strong>Serum survivin levels were considerably higher in psoriasis patients than in controls (70.3 ± 16.9 vs. 22.1 ± 9.4 pg/mL; P < 0.001). Following methotrexate therapy, serum survivin levels decreased (20.9 ± 8.0 pg/mL; P < 0.001) and PASI scores reduced in tandem from 15.3 ± 4.8 to 7.5 ± 4.4 ( P < 0.001). Improvement in PASI was significantly associated with survivin reduction (r = 0.672; P < 0.001).</p><p><strong>Limitations: </strong>Small sample size, short follow-up duration, and lack of histopathological assessment or tissue survivin evaluation. Additionally, the absence of long-term follow-up and potential noncompliance with smoking/alcohol abstinence may have influenced the findings.</p><p><strong>Conclusion: </strong>Serum survivin levels were significantly elevated in psoriasis patients compared to healthy controls and were reduced significantly following treatment with methotrexate. These changes in serum survivin levels corresponded well with decreasing PASI scores in psoriasis patients, suggesting survivin as a potential biomarker of disease activity and therapeutic response.</p>","PeriodicalId":13335,"journal":{"name":"Indian Dermatology Online Journal","volume":"17 5","pages":"688-692"},"PeriodicalIF":2.0,"publicationDate":"2026-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13588454/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148863853","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Gorlin-Goltz Syndrome in an Elderly Patient: Clinical Presentation and Diagnosis.","authors":"Ruchika A Nevse, Arjun Prakashey, Sushil Pande","doi":"10.4103/idoj.idoj_1157_25","DOIUrl":"10.4103/idoj.idoj_1157_25","url":null,"abstract":"","PeriodicalId":13335,"journal":{"name":"Indian Dermatology Online Journal","volume":" ","pages":"764-766"},"PeriodicalIF":2.0,"publicationDate":"2026-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13588452/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148827980","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"A Pink Dome on the Digit: Diagnostic Clues to a Digital Myxoid Cyst.","authors":"Chitwan Kaur Ghuman, Veeranna Shastry","doi":"10.4103/idoj.idoj_1042_25","DOIUrl":"10.4103/idoj.idoj_1042_25","url":null,"abstract":"","PeriodicalId":13335,"journal":{"name":"Indian Dermatology Online Journal","volume":" ","pages":"760-761"},"PeriodicalIF":2.0,"publicationDate":"2026-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13588444/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148163127","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Linear Bulla with Surface Corrugations: Novel Dermoscopy Features in Bullous Cutaneous Larva Migrans.","authors":"Aradhana Rout, Vikas Pathania, Siddharth Mani","doi":"10.4103/idoj.idoj_1138_25","DOIUrl":"10.4103/idoj.idoj_1138_25","url":null,"abstract":"","PeriodicalId":13335,"journal":{"name":"Indian Dermatology Online Journal","volume":" ","pages":"767-768"},"PeriodicalIF":2.0,"publicationDate":"2026-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13588446/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148827985","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"A Questionnaire-based Evaluation of the Impact of District Residency Program on Dermatology Training: Challenges, Experiences, and Need for Reform.","authors":"Bharti Aggarwal, Chander Grover","doi":"10.4103/idoj.idoj_857_25","DOIUrl":"10.4103/idoj.idoj_857_25","url":null,"abstract":"<p><strong>Background: </strong>The District Residency Program (DRP), introduced by the National Medical Commission (NMC), envisages a three-month mandatory posting of all Indian postgraduate (PG) residents in district hospitals. It is aimed at strengthening the district health system; however, its impact on specialty training in dermatology remains unclear.</p><p><strong>Materials and methods: </strong>After obtaining institutional ethical clearance, we conducted an anonymized online survey among dermatology PG residents across India, who had completed their DRP posting. It was based on a pre-designed and validated questionnaire, circulated via social media resident networks. The objective and subjective responses were collated and statistically analyzed.</p><p><strong>Results: </strong>Responses from 292 dermatology residents from government (156, 53.4%), private (91, 31.2%), deemed university (35, 12.1%), and government-aided (10, 3.4%) institutions were analyzed. Majority belonged to the PG-2022 batch (185, 63.4%). A significant hindrance to academics was reported by 96 (39.2%) residents, while it remained unaffected for 46 (15.8%). Thesis work was adversely impacted for 190 (65%) residents, with 133 (45.5%)reporting significant disruption. Dermatology procedural skill training during DRP was limited with no procedural dermatology exposure being reported by 159 (54.5%) respondents, while 42 (14.4%)performed procedures supervised, and 68 (23.3%) performed unsupervised. Accommodation was not provided for 229 (78.4%), while transport was not provided for 259 (88.7%) respondents. Lack of access to hygienic meals (206, 70.5%) and safety concerns (103, 35.3%) were significant issues reported. Regarding training outcomes, communication skills reportedly improved for 133 (45.6%). Exposure to the district health system was rated adequate by only 97 (33.2%), while only 59 (20.2%)felt that DRP strengthened district services. Only 93 (31.9%) agreed with the need for DRP posting during post-graduation, while 98 (33.6%) felt that it hampered their training.</p><p><strong>Limitations: </strong>Lack of formal psychometric validation of the questionnaire, a relatively small sample size, and the use of a voluntary online Google Form survey, which may have introduced selection and response bias.</p><p><strong>Conclusion: </strong>Targeted reforms are essential to align the program with dermatology specialty education, while upholding public health objectives at the same time.</p>","PeriodicalId":13335,"journal":{"name":"Indian Dermatology Online Journal","volume":"17 5","pages":"661-667"},"PeriodicalIF":2.0,"publicationDate":"2026-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13588445/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148864780","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}