Indian Journal of Ophthalmology最新文献

{"title":"Clinicopathological profile of eyelid tumors at a tertiary care center: An observational prospective study.","authors":"Nishi Prasad, Aditi Dubey, Priyanka Patangia, Suraj S Kubrey, Kavita Kumar","doi":"10.4103/IJO.IJO_905_24","DOIUrl":"https://doi.org/10.4103/IJO.IJO_905_24","url":null,"abstract":"<p><strong>Purpose: </strong>The objective of this study was to study the clinical and histological profiles of eyelid tumors.</p><p><strong>Methods: </strong>This is an observational prospective study. A total 78 cases of eyelid tumors for a period of 1 year were included in this study. History was taken and clinical examination and radiological investigations were done as indicated, and all the cases were then subjected to surgical excision/incisional biopsy as per the size and clinical diagnosis. Histopathological examination of eyelid lesions was done, and the eyelid was primarily reconstructed. The data were compiled, and the statistical software SPSS version 20 was used for analysis.</p><p><strong>Results: </strong>A total of 78 cases of eyelid mass were included in this study within the study period. The mean age of the patients was 38.9 years. Out of 78 cases, 52.5% were male, while 47.5% were female. The male: female ratio was 1.05:1. The right-sided lesion was 54%. Benign cases were 66.6%, malignant cases were 18%, and inflammatory cases were 15.4%. Adnexal lesions are mostly benign, while epidermal lesions in elderly are malignant. Histologically, the most common benign lesion was epidermoid cyst and the most common malignant lesion was sebaceous cell carcinoma.</p><p><strong>Conclusion: </strong>There is a vast variety of lid tumors based on tissue origin. Histological examination is essential to ascertain the origin and nature of growth of the eyelid tumors. Epidermal cysts were the most common benign lesions, and sebaceous carcinoma was the most common malignant tumor.</p>","PeriodicalId":13329,"journal":{"name":"Indian Journal of Ophthalmology","volume":" ","pages":""},"PeriodicalIF":2.1,"publicationDate":"2025-04-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144017745","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Lasiodiplodia keratitis: A case series of 27 patients.","authors":"Smruti R Priyadarshini, Alluri Himabindu, Srikant K Sahu, Amrita Mohanty, Himanshu S Behera, Sujata Das","doi":"10.4103/IJO.IJO_1677_24","DOIUrl":"https://doi.org/10.4103/IJO.IJO_1677_24","url":null,"abstract":"<p><strong>Purpose: </strong>To review 27 cases of microbial keratitis caused by Lasiodiplodia theobromae presenting to a tertiary eye care center in eastern India over seven-year period and analyze the risk factors, clinical profile, microbiological characteristics, treatment, and outcome of patients.</p><p><strong>Method: </strong>This is a retrospective review of 27 cases of microbial keratitis diagnosed with Lasiodiplodia theobromae between November 2015 and October 2022. Data were retrieved using the electronic medical record system. Additional outcomes such as average time of resolution, frequency, type, and outcome of surgical interventions, wherever performed, were also analyzed. Descriptive statistics were used to interpret the demographic data.</p><p><strong>Results: </strong>The mean age of patients was 56.8 ± 18.7 years (range: 23-86), the male: female ratio was 2.4:1, and the average follow-up was 90.2 days. Eleven (40.7%) patients had a history of trauma, and 16 (59.3%) presented with a large infiltrate (>6 mm). Samples from all the patients were culture-positive for Lasiodiplodia theobromae, of which 26 (96.3%) were corneal scrapings and one (4%) was a half-corneal button. Eight (29.6%) patients had coexisting bacterial infections. Successful management was achieved in 12 eyes (66.7%) with medical treatment alone (topical natamycin, n = 7; topical natamycin + oral ketoconazole, n = 3; and topical natamycin + topical gatifloxacin, n = 2). However, surgical intervention was required for nine (33.3%) eyes.</p><p><strong>Conclusion: </strong>Medical management with natamycin was effective in treating patients with Lasiodiplodia keratitis. However, advanced cases necessitated surgical intervention for complete resolution.</p>","PeriodicalId":13329,"journal":{"name":"Indian Journal of Ophthalmology","volume":" ","pages":""},"PeriodicalIF":2.1,"publicationDate":"2025-04-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143977513","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Clinico-microbiological profile of post-cataract surgery endophthalmitis and role of polymerase chain reaction in the management: A report from Eastern India.","authors":"Pragati Paul, Sourav Padhi, Ahana Sen, Aarzoo Juneja, Ankeeta Baliarsingh, Eesh Nigam, Maitreyi Chowdhury, Surabhi Chattree, Kalpita Das, Debmalya Das, Rupak Roy","doi":"10.4103/IJO.IJO_2680_24","DOIUrl":"https://doi.org/10.4103/IJO.IJO_2680_24","url":null,"abstract":"<p><strong>Purpose: </strong>To study the clinical and microbiological profile of post-cataract surgery endophthalmitis and assess the utility of eubacterium and panfungal polymerase chain reaction (PCR).</p><p><strong>Methods: </strong>This was a case series of consecutive post-cataract surgery endophthalmitis patients treated at a tertiary care center in eastern India between January 2015 and December 2023. Data on clinical features, investigations, treatment, and outcomes were obtained from medical records. Aqueous or vitreous samples were first analyzed with various stains, including Gram's stain, 10% potassium hydroxide (KOH) mount, Giemsa stain, and Ziehl-Nielsen stain. Further samples were inoculated into cultures. All samples were analyzed with polymerase chain reaction (PCR) to identity eubacterium, panfungal, and Propioniobacterium acnes genomes. Favorable anatomical and functional outcomes were defined as clear media and attached retina and best-corrected visual acuity of 20/200 or better, respectively. The main outcome measure was defined as anatomical and functional outcomes in culture-negative but PCR-positive and negative cases. Chi-square tests were performed for statistical analysis, and a P value of less than 0.05 was considered significant.</p><p><strong>Results: </strong>A total of 132 patients were included. Culture was positive in 51 (38.6%) eyes. Gram-negative bacilli (27; 51.9%) were the predominant microorganisms, with Pseudomonas aeruginosa (11; 21.1%) being the most common isolate. Eubacterium or panfungal PCR were positive in 108 (81.8%) eyes. Among 81 culture-negative patients, 57 had positive PCR results (Group A), and 24 had negative PCR results (Group B). A favorable anatomical outcome was achieved in 51 (76.1%) patients in Group A and 10 (71.4%) in Group B (P = 0.69). A favorable functional outcome was achieved in 50 (74.6%) patients in Group A and 9 (64.3%) patients in Group B (P = 0.44).</p><p><strong>Conclusion: </strong>PCR positivity was higher than conventional culture. Eubacterium and panfungal PCR help in prompt decision-making in culture-negative endophthalmitis.</p>","PeriodicalId":13329,"journal":{"name":"Indian Journal of Ophthalmology","volume":" ","pages":""},"PeriodicalIF":2.1,"publicationDate":"2025-04-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144012129","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Role of a mobile/USB endoscope in dacryology.","authors":"Hare Ram Ojha, Neha Verma, Arunima Gupta, Alka Tripathi","doi":"10.4103/IJO.IJO_2017_24","DOIUrl":"https://doi.org/10.4103/IJO.IJO_2017_24","url":null,"abstract":"<p><strong>Abstract: </strong>To establish the role of a mobile/Universal Serial Bus (USB) endoscope in dacryology. A prospective observational study was conducted at a tertiary ophthalmic institute. A mobile/USB endoscope comprising a 14 cm long camera probe, 5.5 mm in diameter, consisting of a 1.3 MP mini camera and six light-emitting diode adjustable lights, was used for performing nasal endoscopy and therapeutic/minor procedures. This study was divided into three parts: diagnostic, minor, and therapeutic procedures. For diagnostic purposes, nasal endoscopy was performed - preoperative (n = 31) and postoperative (n = 22) dacryocystorhinostomy (DCR) - to identify the six anatomical landmark structures of the nose and patency of the ostium. For a minor procedure, retrieval of the retracted silicone intubation tube (n = 3) was attempted using this endoscope. For therapeutic purposes, endoscope-assisted probing in congenital nasolacrimal duct obstruction (CNLDO) patients (n = 6) and endoscope-assisted lacrimal intubation were attempted in cases of failed DCR (n = 7). Diagnostic endoscopy performed in the outpatient department (OPD) and operating room (OR) in preoperative and postoperative DCR patients was almost 80% (n = 25) and 90% (n = 20) successful, respectively. In the remaining patients, owing to deviated nasal septum (DNS) and hypertrophied turbinates, the endoscopy was partially successful or unsuccessful. The minor procedure performed in the OPD group was 100% (n = 3) successful. The therapeutic procedures performed in OR endoscope-assisted probing in CNLDO and endoscope-assisted lacrimal intubation in failed DCR were ~ 33% (n = 2) and ~ 15% (n = 1) successful, respectively. The USB endoscope is more economical, portable, and easy to handle; hence, it is a more convenient alternative to the standard nasal endoscope for diagnostic purposes in pre- and postoperative cases of DCR and is very useful for office/minor procedures; however, its use is limited for therapeutic purposes.</p>","PeriodicalId":13329,"journal":{"name":"Indian Journal of Ophthalmology","volume":" ","pages":""},"PeriodicalIF":2.1,"publicationDate":"2025-04-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144008518","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Clinical outcomes of DSAEK with pre-cut grafts of thickness more than 150 microns.","authors":"Aravind Roy, Tanvi Mudgil, Nikita Das, Megana Peddi, Sunita Chaurasia","doi":"10.4103/IJO.IJO_2016_24","DOIUrl":"https://doi.org/10.4103/IJO.IJO_2016_24","url":null,"abstract":"<p><strong>Purpose: </strong>To study the clinical outcomes of descemet stripping automated endothelial keratoplasty (DSAEK) with pre-cut lenticules of thickness above 150 microns.</p><p><strong>Methods: </strong>During the study period Jan 2019 to Sept 2020, 1865 pre-cut DSAEK lenticules were prepared at the institute-affiliated eye bank by two trained technicians. Of these, 28 (1.5%) grafts had a thickness >150 microns and were utilized at the institute. Retrospective review of medical records was performed for these patients.</p><p><strong>Results: </strong>Median donor age was 39 (range, 20-62) years, death to preservation time was 6 (range, 0.28-8.4) hours, endothelial cell density (ECD) was 2738 (range, 2203-3788) cells/mm2, graft thickness was 186 (range, 170-250) microns. The mean recipient age was 58 (range, 36-76) years, and 17 were males. The most common indication for surgery was pseudophakic corneal edema (n = 14, 50%). The mean log MAR visual acuity at 1-month, 3-month, and 6-month post-operative visits improved to 0.8, 0.7, and 0.5, respectively. The mean lenticule thickness at 3- and 6-month post-operative period reduced to 161 and 151 microns, respectively. Graft detachment needing rebubbling in 5/28 (17.8%) eyes. Primary graft failure was noted in six (21.4%) eyes, which included one eye that underwent rebubbling. Secondary graft failure was noted in four eyes (14.2%). Eighteen (81.8%. 18/22) eyes were maintained graft clarity till the end of the study period, mean follow-up of 10.5 (range, 3-18) months.</p><p><strong>Conclusions: </strong>With the currently practiced nomograms in automated methods of DSAEK graft preparation, graft thickness over 150 microns can occur infrequently (<1.5%); however, DSAEK lenticules above150 microns can have a favorable outcome in large majority (81.8%). The study noted rebubbling and primary graft failure rate in a fifth of all eyes with lenticule thickness > 150 microns.</p>","PeriodicalId":13329,"journal":{"name":"Indian Journal of Ophthalmology","volume":" ","pages":""},"PeriodicalIF":2.1,"publicationDate":"2025-04-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144008879","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Enhancement using CIRCLE software post cornea lenticule extraction for advanced refractive correction.","authors":"Gitansha S Sachdev, Tasneem Neemuchwala, Shreyas Ramamurthy","doi":"10.4103/IJO.IJO_2186_24","DOIUrl":"https://doi.org/10.4103/IJO.IJO_2186_24","url":null,"abstract":"<p><strong>Purpose: </strong>To report visual outcomes of enhancement after corneal lenticular extraction for advanced refractive correction (CLEAR, Femto LDV) using the CIRCLE software (Carl Zeiss Meditec, Germany).</p><p><strong>Methods: </strong>A prospective interventional study included eyes undergoing enhancement for under-correction or regression following CLEAR; at least three months after the primary procedure. CIRCLE software (pattern D) was used to convert the initial cap into a flap, which was subsequently raised and the stromal bed was ablated using an excimer laser (Zeiss Mel 90), with a Plano target in all eyes. Safety and visual outcomes at the three months postoperative visit were analyzed, with maximum follow-up till one year.</p><p><strong>Results: </strong>Nine eyes of six patients were included in the data analysis. The mean preoperative refractive spherical equivalent treated using the CLEAR software was -5.04 ± 2.28 diopter (D). Enhancement was performed for a mean residual error of -0.86 ± 0.54 D. The CIRCLE procedure was performed 6.67 ± 1.79 months after the primary procedure and resulted in a final manifest spherical equivalent of - 0.01 ± 0.04 D at the three months postoperative visit (P = 0.001867). Mean uncorrected distance visual acuity (UDVA) improved from logMAR 0.31 ± 0.11 to 0.01 ± 0.03 (P = 0.0008). Post-enhancement UDVA of 20/20 or better was achieved in 78% of the eyes. None of the eyes reported loss of lines in corrected distance visual acuity (CDVA). No intraoperative complications were noted in the cohort. No incidence of epithelial ingrowth, regression, or stromal haze was noted up till one year postoperative visit.</p><p><strong>Conclusion: </strong>CIRCLE software may be considered as an optional treatment modality for enhancement following CLEAR.</p>","PeriodicalId":13329,"journal":{"name":"Indian Journal of Ophthalmology","volume":" ","pages":""},"PeriodicalIF":2.1,"publicationDate":"2025-04-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144009463","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Role of oral bio-enhanced curcumin in dry eye disease.","authors":"Dikshit Kapil, Aafreen Bari, Namrata Sharma, Thirumurthy Velpandian, Rajesh Sinha, Prafulla Maharana, Manpreet Kaur, Tushar Agarwal","doi":"10.4103/IJO.IJO_1572_24","DOIUrl":"https://doi.org/10.4103/IJO.IJO_1572_24","url":null,"abstract":"<p><strong>Purpose: </strong>To assess the role of oral bio-enhanced curcumin in dry eye disease (DED).</p><p><strong>Design: </strong>Randomized, double-masked, placebo-controlled clinical study conducted at a tertiary eye center.</p><p><strong>Methods: </strong>Forty patients of bilateral mild to moderate DED were randomized in two groups - group A (topical carboxy methyl cellulose QID + oral placebo) and group B (topical carboxy methyl cellulose QID + oral bio-enhanced curcumin). The objective parameters of DED were quantified at baseline and compared at 3 months follow-up.</p><p><strong>Results: </strong>At three months follow-up, there was significant improvement in curcumin group in terms of Ocular Surface Disease Index (OSDI) score (P = 0.002), tear meniscus height (TMH) (P = 0.002), tear volume (P = 0.006), tear break-up time (TBUT) (P < 0.001), non-invasive break-up time (NIBUT) (P = 0.026), lipid layer thickness (LLT) (P = 0.01), and decrease in bulbar redness (P = 0.002). There was no significant improvement in limbal redness (P = 0.097), corneal-staining score (P = 0.93), and Schirmer's test (P = 0.42). Mild adverse drug reaction was observed in three cases of the curcumin group and one case of group A.</p><p><strong>Conclusions: </strong>Oral bio-enhanced curcumin is a safe and effective treatment modality in cases of mild to moderate DED. It effectively improves the tear film stability, LLT, and TMH and reduces the bulbar redness.</p>","PeriodicalId":13329,"journal":{"name":"Indian Journal of Ophthalmology","volume":" ","pages":""},"PeriodicalIF":2.1,"publicationDate":"2025-04-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144009408","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Microkeratome-assisted vs femtosecond laser-assisted superficial anterior lamellar keratoplasty: A randomized controlled trial.","authors":"Sanjay Kumar Mishra, Mrinalini Singh, Amrita Joshi, Sarvadarshi Shukla, Alok Sati, Anju Pannu, Sonali V Kumar, Jaya Kaushik","doi":"10.4103/IJO.IJO_1454_24","DOIUrl":"https://doi.org/10.4103/IJO.IJO_1454_24","url":null,"abstract":"<p><strong>Purpose: </strong>The purpose is to compare the outcomes between microkeratome-assisted superficial anterior lamellar keratoplasty (MK-SALK) and femtosecond laser-assisted superficial anterior lamellar keratoplasty (FL-SALK) for superficial corneal opacities.</p><p><strong>Methods: </strong>Seventy-five eyes with superficial corneal opacities were prospectively randomized into the MK-SALK control arm and an FL-SALK study arm. Follow-up examinations were set at day 1, day 7, day 30, and at the third and sixth month after the surgery. The primary outcome measure was best-corrected visual acuity (BCVA), whereas secondary outcome measures were contrast sensitivity, corneal aberrations, K-readings, corneal thickness, and complications after the surgery.</p><p><strong>Results: </strong>Seventy-two eyes completed the six-month follow-up interval. An insignificant difference in BCVA was observed at day 30 [control arm (n = 36); 0.80 ± 0.27 logarithm of the minimum angle of resolution (log MAR), study arm (n = 36); 0.78 ± 0.12 log MAR, P = 0.63], at third month [control arm; 0.65 ± 0.28 log MAR, study arm; 0.66 ± 0.10 log MAR, P = 0.93], and sixth month [control arm; 0.61 ± 0.28 log MAR, study arm; 0.62 ± 0.10 log MAR, P = 0.84] following surgery. In addition, an insignificant difference was observed between the two groups in terms of contrast sensitivity, corneal aberration, mean keratometric value, mean central corneal thickness, and complications following surgery.</p><p><strong>Conclusions: </strong>MK-SALK is non-inferior to FL-SALK for the treatment of superficial corneal opacities. By demonstrating comparable outcomes, our study alleviates apprehension and doubts about choosing between the techniques and allows the surgeon to make a choice based on his expertise and resources.</p>","PeriodicalId":13329,"journal":{"name":"Indian Journal of Ophthalmology","volume":" ","pages":""},"PeriodicalIF":2.1,"publicationDate":"2025-04-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144009467","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Contact lenses for visual rehabilitation in post-keratoplasty eyes: A review.","authors":"Mohamed Ibrahime Asif, Nidhi Kalra, Manasi Tripathi, Mrinalini Anand Yadav, Shahnaz Anjum, Rajesh Sinha","doi":"10.4103/IJO.IJO_2394_24","DOIUrl":"https://doi.org/10.4103/IJO.IJO_2394_24","url":null,"abstract":"<p><strong>Abstract: </strong>To assess the role of various types of contact lenses (CL) after penetrating and lamellar keratoplasty, we reviewed all studies that were related to CL fitting in post-keratoplasty (full-thickness and lamellar) eyes between 1990 and 2024 by using relevant search keywords. The demographic data, indications for CL fitting, duration between keratoplasty and CL fitting, CL design and fitting methodologies, refractive outcomes, topographic and biomechanical changes, aberrometry, specular microscopy, corneal thickness, graft survival, and complications were analyzed. A total of 32 original studies and seven case reports were evaluated. All studies showed favorable refractive outcomes. Complications, if any, were managed successfully with conservative treatment and temporary discontinuation of lens wear. Most authors preferred to use large-diameter multicurve rigid-gas permeable lenses and scleral lenses over hydrogels and hybrid or piggy-back varieties, with an inclination toward late fitting due to multiple factors. The lenses did not have any adverse effect on graft survival. CLs are a useful tool in post-keratoplasty visual rehabilitation. However, patients require meticulous workup, a thorough fitting methodology, attention to associated problems, and close follow-up to monitor for complications.</p>","PeriodicalId":13329,"journal":{"name":"Indian Journal of Ophthalmology","volume":" ","pages":""},"PeriodicalIF":2.1,"publicationDate":"2025-04-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143984644","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Risk factors and incidence of Macular Edema in eyes with retinal Vein Occlusion after uneventful cataract surgery: The MEVO study.","authors":"Sagnik Sen, Sourav Damodaran, Prithviraj Udaya, Rachana Mallidi, Chandralakshmi Chandrasekar, Muthukrishnan Vallinayagam, Renu P Rajan, Karthik Kumar, Madhu Shekhar, Naresh Babu Kannan, Kim Ramasamy","doi":"10.4103/IJO.IJO_1700_24","DOIUrl":"https://doi.org/10.4103/IJO.IJO_1700_24","url":null,"abstract":"<p><strong>Purpose: </strong>The current study aims to assess incidence of postoperative macular edema (PME), risk factors behind PME and outcomes after cataract surgery in eyes with retinal vein occlusion (RVO).</p><p><strong>Methods: </strong>This retrospective study included 162 eyes of 162 RVO patients, who underwent cataract surgery between 1 January 2015 and 31 December 2019. Eyes with RVO which did not have cystoid macular edema (CME) on optical coherence tomography (OCT) within the immediate 1 month prior to surgery were included.</p><p><strong>Results: </strong>Patients were followed up for an average duration of 13 ± 10.9 months after cataract surgery (range, 6-60 months). The mean time to PME development was 1.87 ± 1.7 months. Postoperative macular edema developed within 3 months after surgery in 40.1% of all eyes, 21% eyes with no previous CME, 57.3% of eyes with previous CME, and in 50% of eyes of patients with diabetes. Significant risk factors of PME identified were diabetes (OR = 2.1) and previous CME (OR = 4.62) requiring treatment with anti-VEGF (OR = 4.83). The visual acuity (VA) of operated eyes significantly improved from 0.85 ± 0.55 logMAR at baseline to 0.365 ± 0.39 logMAR (P<0.0001) at the final follow-up. A significant proportion of eyes showed improvement of their VA beyond Snellen 6/12 at final follow-up (P < 0.0001); however, eyes with PME had a higher chance of poorer vision gain (worse than 6/18). Poor prognostic factors for vision were presence of PME, previous CME and treatment history with injections, central RVO and poor VA at baseline.</p><p><strong>Conclusion: </strong>The study demonstrates that RVO eyes with previous CME requiring intravitreal treatment are at significant risk of postoperative macular edema after uneventful cataract surgery, and this risk increases in people with diabetes. The incidence is not affected by the type of RVO. Considering almost 2/3rd of PME developed within the 1st month of surgery, we recommend a routine OCT scan as a part of postoperative assessment at the 1st visit after surgery, in eyes at risk. Eyes developing PME may have poorer visual outcomes, especially eyes with CRVO; hence, patients need to be counseled carefully regarding outcomes of cataract surgery. The outcomes might depend on the previous treatment course they have received, and they may need to undergo a repeat cycle of treatment due to a risk of return of macular edema.</p>","PeriodicalId":13329,"journal":{"name":"Indian Journal of Ophthalmology","volume":" ","pages":""},"PeriodicalIF":2.1,"publicationDate":"2025-04-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144009306","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}