Indian Journal of Ophthalmology最新文献

{"title":"Percentage macular ganglion cell complex and peripapillary retinal nerve fiber layer loss in different stages of glaucoma.","authors":"Shah Zalak, Sihota Ramanjit, Sen Ray Swarnali, Choudhary Samiksha, Dhillon Jasleen","doi":"10.4103/IJO.IJO_3238_23","DOIUrl":"https://doi.org/10.4103/IJO.IJO_3238_23","url":null,"abstract":"<p><strong>Purpose: </strong>The purpose of the study is to evaluate the percentage differences in ganglion cell complex (GCC) and peripapillary retinal nerve fiber layer (pRNFL) parameters in fellow eyes of the same patient with varying severities of glaucomatous damage. As only the eyes of the same patient with different severities of glaucoma were included in the present study, it could be inferred that the difference in parameters represents the loss leading to the next stage of glaucoma.</p><p><strong>Methods: </strong>This was a cross-sectional study of 136 adult primary glaucoma eyes of 68 patients. They were divided as follows: Group 1 - normal visual field in one eye and superior nasal step, (mild), in the other, Group 2 - superior nasal step in one eye and superior arcuate scotoma, (moderate) in the other, and Group 3 - superior arcuate scotoma in one eye and biarcuate scotoma, (severe) in the other. GCC and pRNFL measurements on spectral domain optical coherence tomography (SD-OCT) were statistically assessed as applicable.</p><p><strong>Results: </strong>The percentage difference in GCC parameters in fellow eyes from normal field to mild, mild to moderate, and moderate to severe glaucoma in average GCC was 10.04 ± 6.33%, (P = 0.0001), 15.77 ± 9.62%, (P = 0.0001), and 9.06 ± 6.41%, (P = 0.021); in inferior GCC, it was 13.25 ± 8.7%, (P = 0.0002), 18.94 ± 12,61%, (P = 0.0001), and 9.02 ± 6.92%, (P = 0.658), and in superior GCC, it was 7.42 ± 5.79%, (P = 0.002) 15.31 ± 11.07%, (P = 0.004), and 11.23 ± 9.82%,(P = 0.003), respectively. The percentage difference in average pRNFL of fellow eyes from normal field to mild, mild to moderate, and moderate to severe glaucoma in was 16.9 ± 9.85%, (P = 0.001), 18.23 ± 10.47%, (P < 0.0001), and 9.0 ± 7.35%, (P = 0.0004); in inferior pRNFL, it was 18.76 ± 12.38%, (P = 0.001), 19.6 ± 10.3%, (P < 0.0001), and 8.41 ± 7.3%, (P = 0.019), and in superior pRNFL, it was 15.3 ± 9.8%, (P = 0.015), 18.24 ± 13.56%, (P = 0.0003), and 11.46 ± 9.74%, (P = 0.001), respectively. A total of 136 eyes were regrouped by glaucoma severity, and in mild, moderate, and severe glaucoma subgroups. The percentage difference in average GCC was 11.01 ± 9.07%, 17.53 ± 11.29%, and 18.48 ± 11.69%.</p><p><strong>Conclusion: </strong>A percentage difference of GCC and pRNFL values could be used for both diagnosis and progression of glaucoma.</p>","PeriodicalId":13329,"journal":{"name":"Indian Journal of Ophthalmology","volume":"73 Suppl 2","pages":"S308-S312"},"PeriodicalIF":2.1,"publicationDate":"2025-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143467909","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Short-term outcomes of Tanito microhook ab interno trabeculotomy combined with phacoemulsification in primary open-angle glaucoma - A pilot study.","authors":"Ajita Sasidharan, Paraali Shah, Mithun Thulasidas","doi":"10.4103/IJO.IJO_723_24","DOIUrl":"10.4103/IJO.IJO_723_24","url":null,"abstract":"<p><strong>Purpose: </strong>The aim of the study was to assess the early postoperative efficacy and safety of Tanito microhook (TMH) ab interno trabeculotomy combined with phacoemulsification in patients with primary open-angle glaucoma (POAG).</p><p><strong>Methods: </strong>This prospective interventional study was conducted on consecutive patients with visually significant cataract and mild-moderate POAG. All patients underwent a temporal clear corneal phacoemulsification combined with TMH ab interno trabeculotomy. Postoperative evaluation was done on day 1, 1 month, and 3 months. The outcome measures included intraocular pressure (IOP) at different follow-ups and postoperative complications.</p><p><strong>Results: </strong>In total, 30 eyes of 30 patients were included in the study. There were 16 (53.3%) females and 14 (46.7%) males with a mean age of 62.63 ± 6.7 years. The mean IOP reduced from 23.57 ± 1.65 to 17.33 ± 2.84 at 3 months ( P < 0.001). All eyes had a corrected distance visual acuity ≥6/9 at 1 month postoperatively. Postoperative complications included corneal stromal edema in eight (26.7%) eyes, hyphema in four (13.3%) eyes, and IOP spike in one (3.3%) eye.</p><p><strong>Conclusion: </strong>TMH ab interno trabeculotomy combined with phacoemulsification in patients with mild-moderate POAG is an effective and safe procedure with fewer complications.</p>","PeriodicalId":13329,"journal":{"name":"Indian Journal of Ophthalmology","volume":" ","pages":"S250-S253"},"PeriodicalIF":2.1,"publicationDate":"2025-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141579554","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Long-term outcome of surgical management in neovascular glaucoma: A retrospective, multicentric study.","authors":"Julie Pegu, Prerna Garg, Rakesh Shakya, Suneeta Dubey, Debashish Dash, Navjot Ahluwalia, Kushal Pandit, Mukesh Kumar, Monica Gandhi, Atanu Mazumdar","doi":"10.4103/IJO.IJO_3145_23","DOIUrl":"10.4103/IJO.IJO_3145_23","url":null,"abstract":"<p><strong>Purpose: </strong>This study aimed to evaluate and compare surgical outcomes among neovascular glaucoma patients undergoing trabeculectomy (Trab), glaucoma drainage device (GDD) implantation, or trans-scleral cyclophotocoagulation (TSCPC).</p><p><strong>Methods: </strong>This study analyzed the records of 176 neovascular glaucoma cases treated surgically between January 2017 and December 2021 at four Indian centers. Procedures included trabeculectomy with MMC in 80 eyes, GDD implantation in 25 eyes, and TSCPC in 71 eyes. Outcome measures comprised intraocular pressure (IOP) reduction, antiglaucoma medication (AGM) usage, complications, and best-corrected visual acuity (BCVA).</p><p><strong>Results: </strong>Following surgery, all groups exhibited a significant reduction in IOP. One year postoperatively, complete success rates were 42.9% for the implant group, 54.3% for the Trab group, and 33.3% for the TSCPC group, with corresponding qualified success rates of 57.1%, 36.7%, and 58.9%, respectively. Improvement in postoperative vision was noted, with an increase of 0.24 LogMAR in the Trab group, 0.11 in the GDD group, and a decrease of 0.35 in the TSCPC group. Complications occurred in 27% of Trab and 14% of TSCPC cases, while the GDD group experienced a hypertensive phase in 40% of eyes.</p><p><strong>Conclusion: </strong>In managing neovascular glaucoma, trabeculectomy, GDD, and TSCPC provide comparable IOP control, with GDD showing a higher medication dependency. Trabeculectomy yields superior vision outcomes but carries a higher risk of postoperative complications, emphasizing the importance of individualized treatment selection and vigilant postoperative care.</p>","PeriodicalId":13329,"journal":{"name":"Indian Journal of Ophthalmology","volume":" ","pages":"S254-S259"},"PeriodicalIF":2.1,"publicationDate":"2025-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141982204","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"A study on the association of A-scan parameters and intraoperative complications during cataract surgery in eyes with pseudoexfoliation syndrome.","authors":"R Sruthi, Sheshadri J Saikumar","doi":"10.4103/IJO.IJO_1030_24","DOIUrl":"https://doi.org/10.4103/IJO.IJO_1030_24","url":null,"abstract":"<p><strong>Context: </strong>Pseudoexfoliation is a genetically determined condition that causes significant problems during cataract surgery. Although most patients with pseudoexfoliation experience uneventful cataract surgery, complications, when they arise, can be particularly challenging. Therefore, it is crucial to identify those at risk for intraoperative complications during the preoperative assessment.</p><p><strong>Purpose: </strong>To study the association of preoperative A-scan parameters with intraoperative complications of phacoemulsification in eyes with pseudoexfoliation syndrome.</p><p><strong>Setting and design: </strong>This was a retrospective study conducted in a tertiary care center in the private sector in South India.</p><p><strong>Methods: </strong>A retrospective study of 200 eyes of 184 patients with pseudoexfoliation syndrome, who underwent phacoemulsification. Preoperative A-scan measurements (IOLMaster700), best-corrected visual acuity, lens status, and pupil sizes were noted. Intraoperative complications were correlated with A-scan parameters.</p><p><strong>Statistical analysis: </strong>SPSS 26.0 software.</p><p><strong>Results: </strong>Out of 200 study eyes, 34 eyes (17%) had intraoperative complications. Eyes with less anterior chamber (AC) depth (2.74 ± 0.758 mm) or more lens thickness (4.81 ± 0.565 mm) had a significant association (P < 0.05) with intraoperative complications. There was a 36.8% risk for complications in eyes with <2.5 mm AC depth. Eyes with an increased ratio of axial length to AC depth (8.67 ± 1.517) had more chance of complications.</p><p><strong>Conclusions: </strong>Caution should be taken in pseudoexfoliation syndrome patients with shallow AC or thick lenses as there is more risk for complications during cataract surgery.</p>","PeriodicalId":13329,"journal":{"name":"Indian Journal of Ophthalmology","volume":"73 Suppl 2","pages":"S313-S316"},"PeriodicalIF":2.1,"publicationDate":"2025-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143467883","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Analysis of resurgeries following primary glaucoma surgical intervention in a tertiary care center.","authors":"Rajendrababu Sharmila, Kumar Siddharth, Raji K Daniel, Iswarya Mani, S R Krishnadas","doi":"10.4103/IJO.IJO_1410_24","DOIUrl":"https://doi.org/10.4103/IJO.IJO_1410_24","url":null,"abstract":"<p><strong>Purpose: </strong>To analyze the demographic characteristics, causes, risk factors, and outcomes of resurgeries following primary glaucoma surgery.</p><p><strong>Methods: </strong>This retrospective observational study analyzed medical records of patients who underwent resurgeries following primary glaucoma surgeries conducted from January 1, 2018, to December 31, 2020. The investigation included an assessment of preoperative risk factors, reasons prompting resurgery (such as complications or failure), types of interventions, and their respective outcomes.</p><p><strong>Results: </strong>Out of 1147 eyes subjected to primary surgeries, 30 eyes (2.6%) necessitated resurgery within the first year, at a mean interval of 4.2 ± 3.4 months. The resurgery rate for trabeculectomy was 3.3% (13/389), 1.5% (9/592) for phaco-trabeculectomy, and 4.8% (8/166) for tube surgeries. Multivariate analysis identified male gender and higher preoperative intraocular pressure (IOP) as significant risk factors. Uveitic glaucoma (12.1%), traumatic glaucoma (11.1%), and eyes with prior vitreoretinal surgeries (8.5%) exhibited the highest resurgery rates. Early postoperative resurgeries (1-3 months) were predominantly due to surgical complications, while late resurgeries (>3 months) were attributed to primary surgery failure. Resurgeries following trabeculectomy were primarily driven by surgical failure (61.5%), while complications played a major role in phaco-trabeculectomy (66.6%) and tube surgeries (87.5%).</p><p><strong>Conclusion: </strong>We observed an overall resurgery rate of 2.6%, with higher resurgery rates in tube surgeries compared to filtering surgeries. Reasons for resurgery in the early period were complications and those that occurred late were due to surgical failure. Male gender and elevated preoperative IOP were significant risk factors for resurgery.</p>","PeriodicalId":13329,"journal":{"name":"Indian Journal of Ophthalmology","volume":"73 Suppl 2","pages":"S232-S239"},"PeriodicalIF":2.1,"publicationDate":"2025-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143467884","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Mi-OCT assisted endothelial keratoplasty in buphthalmic eyes- 2 year outcomes.","authors":"Suman Lata, Mohamed Ibrahime Asif, Nidhi Kalra, Rajesh Sinha, Tushar Agarwal, Prafulla Kumar Maharana, Jeewan S Titiyal, Namrata Sharma","doi":"10.4103/IJO.IJO_3112_23","DOIUrl":"https://doi.org/10.4103/IJO.IJO_3112_23","url":null,"abstract":"<p><strong>Objective: </strong>To describe long-term outcomes of posterior lamellar [Descemet stripping automated endothelial keratoplasty (DSAEK) and non-Descemet stripping (n-DSAEK)] and the role of microscope-integrated optical coherence tomography (Mi-OCT) in buphthalmic eyes.</p><p><strong>Design: </strong>Retrospective study.</p><p><strong>Methods: </strong>The medical records of all patients who were diagnosed with buphthalmos and underwent Mi-OCT-guided standard DSAEK/n-DSAEK since 2015 were evaluated. Intraoperative difficulties, graft survival, and complications were recorded.</p><p><strong>Results: </strong>A total of 16 eyes of 16 patients (10 males; 6 females) with a mean age of 9.96 + 6.54 years and a mean follow-up of 24.46 + 7.76 months were evaluated. The mean preoperative acuity was 2.03 + 0.39 log MAR, and the mean corneal diameter was 12.89 + 1.0 mm with a corneal thickness of 874.53 + 105 microns. Ten eyes had a clear lens, two had cataracts, three were aphakic, and one was pseudophakic. Descemet membrane scoring was performed in 10 eyes. The mean donor graft size was 9.14 ± 0.30 mm with a lenticule thickness of 135.9 + 44.54 microns. Intraoperatively, all the grafts were attached on Mi-OCT. The final mean acuity was 1.72 + 0.4 log MAR, and the corneal thickness was 596.18 + 89.12. Graft detachment was seen in the immediate postoperative period in 4 eyes that required rebubbling. Two eyes showed pupillary block that was conservatively managed. Following DSAEK, the cornea cleared at 1 month in 81.25% of eyes. One graft failed at the final follow-up. The mean endothelial loss at final follow-up was 29.1%.</p><p><strong>Conclusion: </strong>Primary DSAEK is a preferred surgical technique for buphthalmic eyes with compromised corneas. Mi-OCT could be useful in these eyes for various intraoperative maneuvers and to assess graft status thereby improving the outcomes of the procedure.</p>","PeriodicalId":13329,"journal":{"name":"Indian Journal of Ophthalmology","volume":"73 Suppl 2","pages":"S303-S307"},"PeriodicalIF":2.1,"publicationDate":"2025-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143467905","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Role of Netarsudil as an addition to prostaglandin analog monotherapy in glaucoma patients having an intraocular pressure below 21 mmHg.","authors":"Sumita Mohapatra, Shobhana Rath, Bijnya B Panda, Subhodeep Thakur","doi":"10.4103/IJO.IJO_1495_24","DOIUrl":"https://doi.org/10.4103/IJO.IJO_1495_24","url":null,"abstract":"","PeriodicalId":13329,"journal":{"name":"Indian Journal of Ophthalmology","volume":"73 Suppl 2","pages":"S349-S350"},"PeriodicalIF":2.1,"publicationDate":"2025-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143467910","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Authors' Response to comment on \"Outcomes of bent ab interno needle goniectomy with phacoemulsification in moderate to severe primary open-angle glaucoma\".","authors":"Anand N Bukke, Karthikeyan Mahalingam, Tanuj Dada","doi":"10.4103/IJO.IJO_2481_24","DOIUrl":"https://doi.org/10.4103/IJO.IJO_2481_24","url":null,"abstract":"","PeriodicalId":13329,"journal":{"name":"Indian Journal of Ophthalmology","volume":"73 Suppl 2","pages":"S348"},"PeriodicalIF":2.1,"publicationDate":"2025-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143467885","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Comments on \"the effect of 2% pilocarpine on depth of field in different time intervals among presbyopic subjects\".","authors":"Suraj Kumar Chaurasiya, Pradeep Agarwal","doi":"10.4103/IJO.IJO_2913_24","DOIUrl":"https://doi.org/10.4103/IJO.IJO_2913_24","url":null,"abstract":"","PeriodicalId":13329,"journal":{"name":"Indian Journal of Ophthalmology","volume":"73 Suppl 2","pages":"S350-S351"},"PeriodicalIF":2.1,"publicationDate":"2025-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143467892","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Secondary intraocular lens implantation.","authors":"Murugesan Vanathi","doi":"10.4103/IJO.IJO_481_25","DOIUrl":"https://doi.org/10.4103/IJO.IJO_481_25","url":null,"abstract":"","PeriodicalId":13329,"journal":{"name":"Indian Journal of Ophthalmology","volume":"73 3","pages":"311"},"PeriodicalIF":2.1,"publicationDate":"2025-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143500657","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}