{"title":"Dumbbell technique for iridodialysis repair.","authors":"Anjali Khadia, Rengaraj Venkatesh, Fredrick Moutappa, Arpit Gupta, Swati Upadhyaya","doi":"10.4103/IJO.IJO_2885_24","DOIUrl":"10.4103/IJO.IJO_2885_24","url":null,"abstract":"<p><p>We describe a novel, simple and minimally invasive surgical technique for the repair of iridodialysis, which can be easily adopted by general ophthalmologists and cataract surgeons. Two eyes underwent this a new approach for iridodialysis repair using a 7-0 polypropylene (Prolene) suture. The 7-0 Prolene suture was used to pin the iris to the sclera, with a double flange resembling a dumbbell, one flange resting on the iris and the other on the sclera. With minimal instruments the technique was completed in a single surgical setting. Postoperative outcomes were favourable in both the cases, with improved visual acuity, near normal pupil contour and no hyphema. The technique was associated with minimal intraoperative time, good cosmetic outcomes and stable intraocular pressure. We conclude that this Dumb-Bell technique is a safe, simple, and efficient method for the repair of iridodialysis. It is minimally invasive with reduced risk of complications and can be readily performed by most ophthalmologists, including those with limited experience in complex iris repairs.</p>","PeriodicalId":13329,"journal":{"name":"Indian Journal of Ophthalmology","volume":"73 8","pages":"1213-1217"},"PeriodicalIF":1.8,"publicationDate":"2025-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144730069","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Kepa Balparda, Mauricio Agudelo-Cardona, Francis Ferrari, Tatiana Herrera-Chalarca, Isabela Franco-Sánchez
{"title":"Keratopigmentation in the modern era: A review of current techniques, results, and safety.","authors":"Kepa Balparda, Mauricio Agudelo-Cardona, Francis Ferrari, Tatiana Herrera-Chalarca, Isabela Franco-Sánchez","doi":"10.4103/IJO.IJO_3027_24","DOIUrl":"10.4103/IJO.IJO_3027_24","url":null,"abstract":"<p><p>To conduct a literature review on current knowledge regarding keratopigmentation (KTP), with a particular focus on femtosecond-assisted procedures. A narrative literature review was performed. Academic databases (PubMed, Google Scholar, Cochrane Library, and SciELO) were searched for articles containing the keywords \"keratopigmentation\" and \"corneal tattoo.\" All relevant articles were reviewed, and appropriate ones related to the topic were included in the review. KTP has a variety of indications, including enhancing the aesthetic profile of blind eyes with decompensated corneas and alleviating symptoms related to iris atrophy. The trend of strictly cosmetic KTP has recently gained popularity among several surgeons worldwide. Despite some controversy, most articles reported excellent outcomes associated with KTP, alongside a high safety profile. Histopathological studies have demonstrated that modern micronized pigments are entirely biocompatible. Femtosecond laser-assisted KTP appears to be a safe and effective procedure. However, more long-term studies are necessary to enhance our understanding of the risks associated with strictly cosmetic applications of this technique.</p>","PeriodicalId":13329,"journal":{"name":"Indian Journal of Ophthalmology","volume":"73 8","pages":"1108-1115"},"PeriodicalIF":1.8,"publicationDate":"2025-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144730076","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Commentary on: Evaluation of viewing distance on vision tasks using virtual reality technology for children with intermittent exotropia.","authors":"Isha Chaturvedi, Pradeep Sharma","doi":"10.4103/IJO.IJO_1412_25","DOIUrl":"https://doi.org/10.4103/IJO.IJO_1412_25","url":null,"abstract":"","PeriodicalId":13329,"journal":{"name":"Indian Journal of Ophthalmology","volume":"73 8","pages":"1172-1173"},"PeriodicalIF":1.8,"publicationDate":"2025-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144730066","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Prevalence and etiology of low vision in children of 5-18 years of age using model of community based door to door screening in an urban slum of Delhi.","authors":"Poonam Sharma, Soveeta Rath, Shailja Tibrewal, Shalinder Sabherwal, Suma Ganesh, Zeeshan Siddique, Nasim Akhter","doi":"10.4103/IJO.IJO_1321_24","DOIUrl":"10.4103/IJO.IJO_1321_24","url":null,"abstract":"<p><strong>Purpose: </strong>To study the prevalence and causes of low vision in children 5-18 years of age residing in an urban slum of northern India.</p><p><strong>Methods: </strong>A prospective observational study between May 2021 and March 2022, where door-to-door (DTD) screening was performed in the chosen slum by trained personnel using PEEK acuity software. Children with visual acuity <6/9 in any eye were subsequently referred to the vision center, where cycloplegic refraction and complete ocular evaluation were done by an optometrist and pediatric ophthalmologist, and glasses were prescribed at the vision center. However, those needing further surgical or medical management were referred to the tertiary institute. After complete intervention, the prevalence of low vision was then calculated, and the most attributable cause of low vision was noted for each child. The complete data was divided into four sub-populations based on four gender-age combinations (male and female, younger and older). The prevalence of children with low vision for each sub-population was calculated separately, and then the results were pooled to estimate the prevalence for the entire population.</p><p><strong>Results: </strong>Using a DTD screening model, 106,524 children in the age group of 5-18 years were screened. Of these, 54,541 (51.2%) were males. Amongst 7084 children who were referred from DTD screening to the vision center, 5154 children had visual impairment. After all the required interventions were completed, 110 patients were finally considered to have low vision.</p><p><strong>Conclusion: </strong>The prevalence of low vision in this urban slum was 0.142%. Refractive amblyopia was the major cause of low vision, followed by retinal causes. Identifying low vision early provides families and caregivers with access to appropriate resources, support services, and educational tools that can aid in the child's development.</p>","PeriodicalId":13329,"journal":{"name":"Indian Journal of Ophthalmology","volume":"73 8","pages":"1174-1180"},"PeriodicalIF":1.8,"publicationDate":"2025-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144730123","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Commentary on: Bent ab interno needle goniectomy: Redefining the angle-based approach in glaucoma.","authors":"Manju R Pillai, Tosha Abhay Gujarathi","doi":"10.4103/IJO.IJO_1201_25","DOIUrl":"https://doi.org/10.4103/IJO.IJO_1201_25","url":null,"abstract":"","PeriodicalId":13329,"journal":{"name":"Indian Journal of Ophthalmology","volume":"73 8","pages":"1195-1196"},"PeriodicalIF":1.8,"publicationDate":"2025-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144730065","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Evaluation of green filter leakage in the Worth 4 Dot test: Implications for clinical accuracy.","authors":"Kousar Sidiq, Ronal Vettikattu","doi":"10.4103/IJO.IJO_42_25","DOIUrl":"https://doi.org/10.4103/IJO.IJO_42_25","url":null,"abstract":"","PeriodicalId":13329,"journal":{"name":"Indian Journal of Ophthalmology","volume":"73 8","pages":"1235-1236"},"PeriodicalIF":1.8,"publicationDate":"2025-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144730072","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Artificial intelligence in pediatric eye care: Assessing the necessity and impact.","authors":"Venugopal Anitha, Meenakshi Ravindran","doi":"10.4103/IJO.IJO_899_25","DOIUrl":"https://doi.org/10.4103/IJO.IJO_899_25","url":null,"abstract":"","PeriodicalId":13329,"journal":{"name":"Indian Journal of Ophthalmology","volume":"73 8","pages":"1219-1221"},"PeriodicalIF":1.8,"publicationDate":"2025-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144730148","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Efficacy and safety of various Intravenous Methylprednisolone regimens in Moderate to Severe Thyroid Eye Disease: A systematic review.","authors":"Ankita Aishwarya, Divanshi Shrivastava, Adarsh Kumar Singh, Rachna Agrawal","doi":"10.4103/IJO.IJO_1808_24","DOIUrl":"10.4103/IJO.IJO_1808_24","url":null,"abstract":"<p><p>This systematic review aims to assess the efficacy and safety of various intravenous methylprednisolone (IVMP) protocols for treating active moderate to severe thyroid eye disease (TED) and to find the most effective regimen with the least side effects. We conducted a comprehensive literature search adhering to PRISMA guidelines across PubMed, Medline, Embase, Web of Science, and Scopus databases from March 2008 to March 2024 to find relevant studies. Included studies were randomized controlled trials (RCTs), nonrandomized trials, cohort studies, case-control studies, case series, and case reports in English, investigating IVMP usage in adults with active moderate to severe TED. Outcomes focused on disease activity, exophthalmos improvement, diplopia resolution, recurrence, need of additional treatment, and associated adverse events. Of the 274 screened articles, 15 were included, involving 1065 participants. There were six RCTs (two multicentric), six retrospective studies, and three prospective case series from March 2008 to March 2024. Regimens were categorized into low dose (LD) ≤ 2.5 g, medium dose (MD) >2.5 g to 4.5 g, and high dose (HD) >4.5 g, with intervals of daily, weekly (most common), and monthly, over 4 to 26 weeks, typically 12 weeks. The MD (4.5 g) regimen was the most common followed, and it significantly improved Clinical Activity Score and quality of life with low side effects. The main limitations of this study are the heterogeneity of included studies, duration of follow-up, and IVMP regimens, which may affect the comparability and generalizability of the results. The weekly IVMP (4.5 g) regimen optimally treats moderate to severe TED. However, future research should focus on large-scale trials to determine the optimal IVMP regimen while addressing variability in managing recurrence, additional treatments, and the timing of rehabilitative surgeries.</p>","PeriodicalId":13329,"journal":{"name":"Indian Journal of Ophthalmology","volume":"73 8","pages":"1100-1107"},"PeriodicalIF":1.8,"publicationDate":"2025-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144730071","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Hanith R Deivarajan, Kanmani Senthilkumar, Hari V Sekar, Vignesh Elamurugan, Jaishree Pandian, Anitha Venugopal, Dharmalingam Kuppamuthu, Lalitha Prajna, Venkatesh N Prajna, Siddharth Narendran
{"title":"Rapid one-tube RPA-coupled CRISPR/Cas12a-based RID-MyC assay for the diagnosis of fungal keratitis.","authors":"Hanith R Deivarajan, Kanmani Senthilkumar, Hari V Sekar, Vignesh Elamurugan, Jaishree Pandian, Anitha Venugopal, Dharmalingam Kuppamuthu, Lalitha Prajna, Venkatesh N Prajna, Siddharth Narendran","doi":"10.4103/IJO.IJO_1613_24","DOIUrl":"10.4103/IJO.IJO_1613_24","url":null,"abstract":"<p><strong>Purpose: </strong>This study introduces and evaluates the single-tube rapid identification of mycoses using CRISPR (ST-RID-MyC) assay. This novel diagnostic tool combines recombinase polymerase amplification (RPA) with CRISPR/Cas12a for the rapid and precise diagnosis of fungal keratitis (FK).</p><p><strong>Design: </strong>Prospective cross-sectional study.</p><p><strong>Methods: </strong>Corneal scrapings from 61 patients with suspected microbial keratitis were collected at the Cornea Department of a Tertiary Eye Care Center. The study assessed the sensitivity, specificity, positive predictive value (PPV), and negative predictive value (NPV) of the ST-RID-MyC assay. Additional measures included concordance rates with traditional diagnostic methods and the time to diagnosis.</p><p><strong>Results: </strong>The ST-RID-MyC assay exhibited a sensitivity of 90% and a specificity of 90.48%, with a PPV of 94.74% and an NPV of 82.61%. The ST-RID-MyC showed substantial agreement with culture and microscopy and perfect concordance with conventional RID-MyC. The mean time to diagnosis was significantly reduced (P < 0.001) using the ST-RID-MyC assay, compared to the traditional RID-MyC assay (6 vs. 32 minutes). Visual assessments demonstrated a high level of inter-observer agreement (kappa = 0.832).</p><p><strong>Conclusions: </strong>The ST-RID-MyC assay, combining RPA and CRISPR/Cas12a in a single-tube system, offers a rapid, accurate, and resource-efficient diagnostic method for FK, potentially transforming clinical management of this condition by enabling faster therapeutic decisions.</p>","PeriodicalId":13329,"journal":{"name":"Indian Journal of Ophthalmology","volume":"73 8","pages":"1208-1212"},"PeriodicalIF":1.8,"publicationDate":"2025-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144730125","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}