Indian Journal of Ophthalmology最新文献

Pinpointing a leaky bleb with a blue surgical skin marker. 用外科手术用的蓝色皮肤记号笔精确定位漏出的水泡。

IF 1.8 4区医学

Indian Journal of Ophthalmology Pub Date : 2025-10-01 Epub Date: 2025-09-25 DOI: 10.4103/IJO.IJO_1059_25

Sarang P Lambat, Nivea Surana, Prabhat V Nangia, Vinay B Nangia

引用次数: 0

Risk factors for generalization of ocular myasthenia gravis. 眼部重症肌无力的危险因素。

IF 1.8 4区医学

Indian Journal of Ophthalmology Pub Date : 2025-10-01 Epub Date: 2025-09-25 DOI: 10.4103/IJO.IJO_650_25

Ivana S Djordjevic, Stojan Peric, Stefan A Djordjevic, Dragana Lavrnic, Kristina Marasevic, Slobodan Apostolski, Ana Kosac, Ivana Basta

{"title":"Risk factors for generalization of ocular myasthenia gravis.","authors":"Ivana S Djordjevic, Stojan Peric, Stefan A Djordjevic, Dragana Lavrnic, Kristina Marasevic, Slobodan Apostolski, Ana Kosac, Ivana Basta","doi":"10.4103/IJO.IJO_650_25","DOIUrl":"https://doi.org/10.4103/IJO.IJO_650_25","url":null,"abstract":"Purpose: To identify potential risk factors for the generalization of ocular myasthenia gravis (OMG).Design: Retrospective cohort study.Methods: This study was conducted at a tertiary neurology clinic between January 2007 and January 2018. A total of 209 patients with myasthenia gravis (MG) presenting with initial ocular involvement were included. Multivariable binary logistic regression was performed to assess the relationship between potential risk factors and disease generalization.Results: Generalization occurred in 65.6% of patients, while 34.4% remained with pure OMG during a median follow-up period of 74 months (range, 24-206 months). Among those who developed generalized MG (GMG), 84.7% did so within the first two years. The overall regression model was statistically significant (p < 0.001), with a Nagelkerke R² value of 0.536, indicating a good model fit. Female sex, elevated acetylcholine receptor (AChR) antibody titers, and a positive repetitive nerve stimulation (RNS) test were identified as statistically significant predictors of disease generalization.Conclusions: The majority of patients with OMG develop generalized disease within the first two years. Major risk factors for generalization include female sex, elevated AChR antibody titers, and abnormal findings on RNS testing.","PeriodicalId":13329,"journal":{"name":"Indian Journal of Ophthalmology","volume":"73 10","pages":"1460-1465"},"PeriodicalIF":1.8,"publicationDate":"2025-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145137444","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Orbital and Adnexal IgG4-related disease: An insight into the clinical profile and management outcomes. 眼眶和附件igg4相关疾病：对临床概况和治疗结果的见解

IF 1.8 4区医学

Indian Journal of Ophthalmology Pub Date : 2025-10-01 Epub Date: 2025-09-25 DOI: 10.4103/IJO.IJO_2546_24

Prabrisha Banerjee, Md Shahid Alam, Kirthi Koka, Bipasha Mukherjee, Subramanian Krishnakumar

{"title":"Orbital and Adnexal IgG4-related disease: An insight into the clinical profile and management outcomes.","authors":"Prabrisha Banerjee, Md Shahid Alam, Kirthi Koka, Bipasha Mukherjee, Subramanian Krishnakumar","doi":"10.4103/IJO.IJO_2546_24","DOIUrl":"https://doi.org/10.4103/IJO.IJO_2546_24","url":null,"abstract":"Purpose: IgG4-related disease is a multisystem disorder involving the orbit and adnexa. The purpose of the present study is to report the varied clinical presentations of IgG4-related ophthalmic disease (IgG4 ROD) and their management outcomes.Methods: This was a retrospective study carried out between January 2013 and December 2020. All patients fulfilling the criteria for diagnosis after histopathological and hematological examinations were included in the study. Demographic data, ophthalmic and radiological findings, surgical details, and management outcomes were analyzed.Results: A total of 21 patients (25 eyes) were included in this study. Twelve were females (57.1%), and nine (42.9%) were males. Four patients (19%) had bilateral involvement. Extraocular muscles (EOMs) and orbital soft tissue were the most common sites involved (n = 13, 52% and n = 12, 48%, respectively). Lacrimal gland was involved in eight cases (n = 8, 32%). Eleven eyes (44%) had multiple periocular and adnexal site involvement. Serum IgG4 titer was found to be elevated in 14 cases (66.7%). All the cases were treated with the oral steroid. Adjuvant immunosuppressant was recommended in seven cases (33%). Recurrence was observed in seven cases (33.3%) at a mean interval of 21.1 ± 16.1 months, and it was found to be three times more common in patients with raised serum IgG4 levels and those with EOM involvement.Conclusion: IgG4 ROD is a rare orbital and adnexal disorder. It can be associated with raised serum Ig G4 levels and systemic evaluation is mandatory. Steroids remain the main stay of management with immunosuppressants being added in refractory cases.","PeriodicalId":13329,"journal":{"name":"Indian Journal of Ophthalmology","volume":"73 10","pages":"1449-1454"},"PeriodicalIF":1.8,"publicationDate":"2025-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145137451","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

An update in vernal keratoconjunctivitis. 春季角膜结膜炎的最新进展。

IF 1.8 4区医学

Indian Journal of Ophthalmology Pub Date : 2025-10-01 Epub Date: 2025-09-25 DOI: 10.4103/IJO.IJO_2362_25

Murugesan Vanathi

引用次数: 0

Comment on: Lag time for diagnosis and treatment in 1120 retinoblastoma children: Analysis from INPOG-RB-19-01. 来自INPOG-RB-19-01的1120例儿童视网膜母细胞瘤的诊断和治疗滞后时间分析

IF 1.8 4区医学

Indian Journal of Ophthalmology Pub Date : 2025-10-01 Epub Date: 2025-09-25 DOI: 10.4103/IJO.IJO_1940_25

Ritesh Verma, Bolajoko A Adewara

引用次数: 0

Pilocarpine 1.25% efficacy for management of uncorrected presbyopia (PILE-UP study). 匹罗卡品治疗未矫正老花眼的疗效为1.25%（堆积研究）。

IF 1.8 4区医学

Indian Journal of Ophthalmology Pub Date : 2025-10-01 Epub Date: 2025-09-25 DOI: 10.4103/IJO.IJO_96_25

Rohit Saxena, Vinay Gupta, Thirumurthy Velpandian, Tanya Nidhi, Himani Thakur, Jeewan S Titiyal, Namrata Sharma

{"title":"Pilocarpine 1.25% efficacy for management of uncorrected presbyopia (PILE-UP study).","authors":"Rohit Saxena, Vinay Gupta, Thirumurthy Velpandian, Tanya Nidhi, Himani Thakur, Jeewan S Titiyal, Namrata Sharma","doi":"10.4103/IJO.IJO_96_25","DOIUrl":"https://doi.org/10.4103/IJO.IJO_96_25","url":null,"abstract":"Purpose: This study aimed to evaluate the efficacy and safety of pilocarpine 1.25% eye drops for improving near vision acuity in presbyopic individuals.Design: Prospective interventional single-arm clinical trial.Methods: This single-arm prospective interventional trial includes 50 presbyopic individuals aged between 40 to 55, administered pilocarpine 1.25% eye drops daily once (9 am, Hour 0) for one month. Visual parameters, including distance corrected near visual acuity (DCNVA), near add power, amplitude of accommodation (AoA), and depth of focus (DoF) along with ocular biometric parameters, were assessed at baseline and after one month at hour 3 (12 noon) and hour 6 (3 pm). Adverse effects were monitored.Results: After one month of pilocarpine treatment, a significant improvement was observed in DCNVA (0.64 ± 0.2 to 0.26 ± 0.11, P < 0.001) along with a decrease in near add power (1.43 ± 0.43 D to 0.42 ± 0.22 D, P < 0.001). The AoA increased (3.23 ± 0.74 D to 3.92 ± 0.93 D, P: 0.005), and DoF widened (0.72 ± 0.18 D to 0.81 ± 0.26 D, P: 0.038). No change in ocular biometry parameters was observed. The change in DCNVA showed strong positive correlations with change in near add (r: 0.84, P: <0.001) and AoA (r: 0.66, P: 0.04). Adverse effects were mild and did not lead to discontinuation.Conclusion: Pilocarpine 1.25% eye drops demonstrated statistically significant improvements in DCNVA, near add, AoA, and DoF after one month of treatment. Pilocarpine 1.25% eye drops shown increase in the AoA and DoF; without any significant change in ocular biometry parameters. The use of pilocarpine 1.25% eye drops can be an alternative intervention for enhancing near vision acuity of presbyopic subjects.","PeriodicalId":13329,"journal":{"name":"Indian Journal of Ophthalmology","volume":"73 10","pages":"1486-1490"},"PeriodicalIF":1.8,"publicationDate":"2025-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145137469","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Compliance to atropine for myopia progression and its socioeconomic and behavioral determinants. 阿托品治疗近视进展的依从性及其社会经济和行为决定因素

IF 1.8 4区医学

Indian Journal of Ophthalmology Pub Date : 2025-10-01 Epub Date: 2025-09-25 DOI: 10.4103/IJO.IJO_949_25

Rohan Arora, Ankita Bisani, Akila Chandrasekaran, Saranya Settu, Yogapriya Vijayaragavan

引用次数: 0

Commentary: Virtual reality counseling in cataract surgery - Using a smartphone-based tool "InSight". 评论：白内障手术中的虚拟现实咨询-使用基于智能手机的工具“InSight”。

IF 1.8 4区医学

Indian Journal of Ophthalmology Pub Date : 2025-10-01 Epub Date: 2025-09-25 DOI: 10.4103/IJO.IJO_2958_24

Anahita Shroff, Kunal Mandlik, P L Sudha, Haripriya Aravind, Rengaraj Venkatesh, R Kartic

引用次数: 0

Parental awareness and knowledge of myopia, its progression, and control: Findings from Goa. 父母对近视的认识、进展和控制：果阿邦的调查结果。

IF 1.8 4区医学

Indian Journal of Ophthalmology Pub Date : 2025-10-01 Epub Date: 2025-09-25 DOI: 10.4103/IJO.IJO_1318_25

Melisa Silveira, Borkar Sanika, Harshada N Narvekar, Ugam P S Usgaonkar

引用次数: 0

Foam Sclerotherapy as an alternate method for Periorbital Dermoid cases with Surgical Constraints: A Prospective study. 泡沫硬化疗法作为眼眶周围皮样病例手术限制的替代方法：一项前瞻性研究。

IF 1.8 4区医学

Indian Journal of Ophthalmology Pub Date : 2025-10-01 Epub Date: 2025-09-25 DOI: 10.4103/IJO.IJO_3086_24

Ankita Aishwarya, Adarsh K Singh, Rachna Agrawal, Vishwas Kapoor, Neha Nigam

{"title":"Foam Sclerotherapy as an alternate method for Periorbital Dermoid cases with Surgical Constraints: A Prospective study.","authors":"Ankita Aishwarya, Adarsh K Singh, Rachna Agrawal, Vishwas Kapoor, Neha Nigam","doi":"10.4103/IJO.IJO_3086_24","DOIUrl":"https://doi.org/10.4103/IJO.IJO_3086_24","url":null,"abstract":"Objective: To analyze the efficacy and safety of foam sclerotherapy in medically unfit patients with periorbital dermoid cysts.Design: This was a prospective interventional single-center study conducted from February 2018 to January 2024.Participants: All patients who were diagnosed with periorbital cysts and were medically unfit for surgery were included in the study.Methods: All patients were treated with foam sclerotherapy using 3% sodium tetradecyl sulfate (STS). The cyst was aspirated using a wide-bore needle, followed by the injection of intralesional foam sclerotherapy in a ratio of 2:1 of the aspirate. The aspirated contents were sent for cytopathology. Outcome measures included regression of the lesion, side-effects, and recurrence.Result: Eleven patients were included in the study who were diagnosed with periorbital dermoid, and all were medically unfit for the surgery. Cysts were located in the medial angular region (four cases), lateral (three cases), intradiploic (two cases), and medial canthus (two cases). Comorbidities included poorly controlled diabetes with chronic kidney disease (five patients), severe coronary insufficiency (three patients), hypercoagulable states (two patients), and restrictive pulmonary disease with severe trismus (one patient). The mean aspirate was 3.5 mL, and a range of 1-3 injections was required. At a mean follow-up of 22.6 months, 82% showed complete remission. Two patients had partial resolution. There were no sclerotherapy-related complications or recurrence.Conclusion: Foam sclerotherapy with 3% STS is a safe and effective alternative for treating periorbital dermoid in medically unfit patients. It helps to achieve complete resolution in the majority of cases without significant complications.","PeriodicalId":13329,"journal":{"name":"Indian Journal of Ophthalmology","volume":"73 10","pages":"1455-1459"},"PeriodicalIF":1.8,"publicationDate":"2025-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145137487","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0