Prajakta Dandekar, Somasheila I Murthy, Maneck D Nicholson, Jay U Sheth, Vaibhav Nagpal, Supriya Sharma
{"title":"Retropupillary iris-claw intraocular lens: A surgical video-based commentary on common pitfalls and training insights.","authors":"Prajakta Dandekar, Somasheila I Murthy, Maneck D Nicholson, Jay U Sheth, Vaibhav Nagpal, Supriya Sharma","doi":"10.4103/IJO.IJO_674_25","DOIUrl":"https://doi.org/10.4103/IJO.IJO_674_25","url":null,"abstract":"","PeriodicalId":13329,"journal":{"name":"Indian Journal of Ophthalmology","volume":"73 10","pages":"1538-1541"},"PeriodicalIF":1.8,"publicationDate":"2025-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145137462","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Effectiveness of binocular vision therapy in managing patients with intermittent exotropia.","authors":"Affan Ashfaque Ahmed Ansari, Pradeep Sharma, Erum W Khateeb, Faiza Bhombal, Shruti Lad, Varsha Jain, Areeba Usmani, Antariksh Jain, Md Oliullah Abdal","doi":"10.4103/IJO.IJO_724_25","DOIUrl":"https://doi.org/10.4103/IJO.IJO_724_25","url":null,"abstract":"<p><strong>Purpose: </strong>Evaluating the effect of binocular vision training (BVT) on Newcastle Control Score (NCS)-Home, near stereopsis and convergence amplitudes in intermittent exotropia (IXT).</p><p><strong>Design: </strong>Retrospective observational study.</p><p><strong>Methods: </strong>30 subjects diagnosed with IXT underwent online BVT with the BYNOCS® program. The BVT was divided into three phases (Phase 1, 2, and 3) for 20 sessions. The frequency was reduced to twice a week as a maintenance therapy. The vision training included antisuppression in the form of dichoptic therapy and exercises to enhance stereopsis and convergence. Evaluation of NCS-Home, Near Stereopsis, and convergence amplitude was conducted both before and after the training program.</p><p><strong>Results: </strong>Nonparametric statistical tests were applied for the data analysis. The median age of the subjects was 14.5 years (10-22.75). Out of them, 13 were female and 17 male. The NCS-Home improved from 2 (1-3) to 0 (0-0) post BVT. The stereopsis changed from 1.48 log units (1.47-1.77) to 2.30 log units (2.07-2.47). The median convergence break point improved from 14 Prism Diopter, PD (4-20), to 38 PD (32-40). The median convergence recovery point improved from 6.25 PD (2-13.5) to 37 PD (30-40) post BVT. Wilcoxon signed-rank test showed significant improvement (P < 0.001) in all aforementioned parameters.</p><p><strong>Conclusion: </strong>BVT for 20 online sessions is an effective method to improve control of IXT with improvement in NCS-Home, Near Stereopsis, and convergence amplitudes.</p>","PeriodicalId":13329,"journal":{"name":"Indian Journal of Ophthalmology","volume":"73 10","pages":"1422-1425"},"PeriodicalIF":1.8,"publicationDate":"2025-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145137490","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Premjith Muraleedharan, Josephine S Christy, Naveen Radhakrishnan
{"title":"Outcomes of anterior chamber wash with adjuvant intracameral and intrastromal voriconazole in deep stromal fungal keratitis with endoexudates - A retrospective study.","authors":"Premjith Muraleedharan, Josephine S Christy, Naveen Radhakrishnan","doi":"10.4103/IJO.IJO_132_25","DOIUrl":"10.4103/IJO.IJO_132_25","url":null,"abstract":"<p><strong>Study design: </strong>Retrospective observational study.</p><p><strong>Purpose: </strong>To analyze the clinical outcomes of patients with deep stromal fungal keratitis with endoexudates who received adjuvant anterior chamber (AC) wash with intracameral (IC) and intrastromal (IS) voriconazole.</p><p><strong>Methods: </strong>Demographics, risk factors, clinical course, microbiology, and visual outcomes of patients with deep-seated fungal keratitis who underwent AC wash with IC and IS voriconazole from January 2022 to December 2022 with at least 6 months post-op follow-up visits were analyzed.</p><p><strong>Results: </strong>The mean age of 40 patients was 53 ± 12 years, and the mean time to presentation was 12 ± 8 days. The mean size of the ulcer at presentation was 21 ± 11.7 square mm. Aspergillus flavus was the most isolated organism in 16 (40%) patients. Seven (17.5%) patients achieved complete resolution with scarring and 33 (82.5%) required therapeutic keratoplasty (TPK), out of which 10 (30.3%) had reinfection.</p><p><strong>Conclusion: </strong>AC wash with IC and IS voriconazole was ineffective as adjuvant therapy in cases of deep-seated fungal keratitis.</p>","PeriodicalId":13329,"journal":{"name":"Indian Journal of Ophthalmology","volume":" ","pages":"1482-1485"},"PeriodicalIF":1.8,"publicationDate":"2025-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144659115","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Management of refractory persistent epithelial defect treatment with topical insulin: An Indian pilot study.","authors":"Parul Jain, Avani Hariani, Isha Gupta, Gahan Reddy","doi":"10.4103/IJO.IJO_2935_24","DOIUrl":"https://doi.org/10.4103/IJO.IJO_2935_24","url":null,"abstract":"<p><strong>Purpose: </strong>To evaluate the safety and efficacy of topical insulin in managing refractory persistent epithelial defects (PEDs) and its potential to prevent complications and surgical intervention.</p><p><strong>Methods: </strong>This prospective interventional study involved 22 patients aged >18 years with PEDs refractory to standard care. Patients with neurotrophic keratitis (8), chemical injury (3), neuroparalytic keratitis (1), and postcorneal transplant (10) were included. Topical insulin eye drops (1 IU/ml), prepared with regular insulin in a polyethylene glycol base, were administered four times a day. Patients were monitored over 6 months, with the size and extent of the epithelial defect assessed at each visit.</p><p><strong>Result: </strong>The mean area of the PED before treatment was 13.17 ± 9.7 mm². The average duration between the diagnosis of PED and the initiation of insulin eye drops was 13.2 ± 4 days. Complete healing was achieved in 17 of 22 eyes (77.2%) within 1 month and in 19 of 22 eyes (86%) within 6 weeks. The average reepithelization time was 21.5 ± 8.8 days. Best-corrected visual acuity improved significantly, from 1.1 ± 0.2 logMAR units to 0.8 ± 0.3 logMAR units (P < 0.001). No cases of PED recurrence were observed during the follow-up period.</p><p><strong>Conclusion: </strong>Topical insulin eye drops promote healing of refractory PEDs, demonstrating good ocular and systemic tolerance. However, long-term and comparative studies are needed to confirm their safety and to support their potential inclusion as a first-line treatment for PED management.</p>","PeriodicalId":13329,"journal":{"name":"Indian Journal of Ophthalmology","volume":"73 10","pages":"1513-1519"},"PeriodicalIF":1.8,"publicationDate":"2025-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145137404","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Mahmut Asfuroğlu, Yonca Asfuroğlu, Cenk Zeki Fikret
{"title":"A quantitative assessment of the corneal endothelium and transparency after Kahook dual blade goniotomy combined with phacoemulsification.","authors":"Mahmut Asfuroğlu, Yonca Asfuroğlu, Cenk Zeki Fikret","doi":"10.4103/IJO.IJO_668_25","DOIUrl":"https://doi.org/10.4103/IJO.IJO_668_25","url":null,"abstract":"<p><strong>Purpose: </strong>To evaluate the effects of Kahook dual-blade (KDB) goniotomy combined with phacoemulsification on corneal endothelial health and transparency.</p><p><strong>Design: </strong>Prospective comparative study.</p><p><strong>Methods: </strong>Sixty-four patients were enrolled: 32 underwent combined KDB goniotomy and phacoemulsification (phaco+KDB), and 32 underwent phacoemulsification alone. Corneal densitometry (CD), endothelial cell density (ECD), central corneal thickness (CCT), coefficient of variation (CV), hexagonality (HEX), and intraocular pressure (IOP) were measured preoperatively and at 1 and 3 months postoperatively.</p><p><strong>Results: </strong>The phaco+KDB group demonstrated a significant reduction in IOP postoperatively (P < 0.001). There were no significant differences between the two groups in the changes in ECD, HEX, CCT, or CV at either postoperative time point (P > 0.05). However, in the phaco+KDB group, CD values demonstrated a statistically significant decrease in the anterior 0-2 mm, 2-6 mm, and central 0-2 mm zones at both 1 and 3 months postoperatively (P < 0.001).</p><p><strong>Conclusion: </strong>KDB goniotomy combined with phacoemulsification resulted in a similar impact on corneal endothelial parameters as phacoemulsification alone, suggesting no additional endothelial risk. The observed improvement in CD suggests enhanced transparency in the early postoperative period, possibly because of IOP reduction. These findings support the safety of KDB as a microinvasive glaucoma surgery that does not require permanent implants and may offer additional benefits in corneal clarity postoperatively.</p>","PeriodicalId":13329,"journal":{"name":"Indian Journal of Ophthalmology","volume":"73 10","pages":"1491-1496"},"PeriodicalIF":1.8,"publicationDate":"2025-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145137466","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Updates in the treatment of neovascular glaucoma: From conventional approaches to novel therapies.","authors":"Saurabh Verma, Neha Midha, Hemlata Udenia, Tanuj Dada","doi":"10.4103/IJO.IJO_841_25","DOIUrl":"https://doi.org/10.4103/IJO.IJO_841_25","url":null,"abstract":"<p><p>Neovascular glaucoma (NVG) is a severe and refractory form of secondary glaucoma characterized by the proliferation of abnormal vessels in the anterior segment, leading to a progressive rise in intraocular pressure (IOP) and optic nerve damage. It is most commonly associated with ischemic retinal conditions such as diabetic retinopathy, central retinal vein occlusion, and ocular ischemic syndrome. This review aims to provide an updated overview of the current management strategies for NVG, including recent advancements in medical, laser, and surgical treatment modalities. While anti-vascular endothelial growth factor (VEGF) agents have revolutionized early NVG management, panretinal photocoagulation (PRP) remains the cornerstone of ischemia management, with enhancements in laser delivery improving efficacy and safety. Filtration surgeries like trabeculectomy and glaucoma drainage devices offer equivocal results in NVG, and on the other hand, safer cyclodestructive methods like transscleral micropulse and endoscopic cyclophotocoagulation (ECP) have emerged as promising alternatives with reduced complications. The management of NVG requires a multimodal approach involving the primary physician, retina specialist, and a glaucoma specialist with treatment tailored to disease severity and underlying retinal pathology. Further research is needed to optimize treatment algorithms and explore emerging therapies for this challenging condition.</p>","PeriodicalId":13329,"journal":{"name":"Indian Journal of Ophthalmology","volume":"73 10","pages":"1412-1421"},"PeriodicalIF":1.8,"publicationDate":"2025-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145137259","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"ASTRA 90 - Aravind slit lamp and training retinal assessment tool.","authors":"Vedant Sharma, Athul S Puthalath, Kim Ramasamy","doi":"10.4103/IJO.IJO_1172_25","DOIUrl":"https://doi.org/10.4103/IJO.IJO_1172_25","url":null,"abstract":"<p><p>Slit-lamp biomicroscopy using a 90-diopter (90D) lens is a standard technique employed by ophthalmologists for detailed evaluation of the posterior segment. However, this skill has a steep learning curve, and it takes time before the clinician gets hold of it, especially in the initial days of residency. In a country like India, characterized by a substantial patient burden and extended waiting times where the healthcare system faces considerable strain, we created a learning tool for new residents to learn fundus examination on slit lamp with 90D lens. We developed a 3D-printed eyeball which is optically similar to the human eye and aids students in grasping this skill at a faster rate. This model is incorporated by a retina film which can be changed, and a beginner in ophthalmology can view both normal and pathological fundi. It enables trainees to simulate the optical and procedural aspects of performing a 90D fundus examination in a controlled, risk-free environment.</p>","PeriodicalId":13329,"journal":{"name":"Indian Journal of Ophthalmology","volume":"73 10","pages":"1530-1532"},"PeriodicalIF":1.8,"publicationDate":"2025-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145137481","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"The etiological spectrum of epiphora: Functional epiphora as an overlooked cause.","authors":"Nurşen Öncel Acır, Servet Cetinkaya","doi":"10.4103/IJO.IJO_1641_24","DOIUrl":"https://doi.org/10.4103/IJO.IJO_1641_24","url":null,"abstract":"<p><strong>Purpose: </strong>To investigate the etiologies of patients presenting with epiphora at a tertiary hospital ophthalmology clinic and the frequency of functional epiphora among these etiologies and to examine the diagnostic value of the combined use of lacrimal syringe and dacryoscintigraphy (DSG).</p><p><strong>Methods: </strong>The patients who presented with symptomatic epiphora between January 2022 and December 2023 and who underwent ophthalmologic examination, lacrimal syringing, and DSG were retrospectively evaluated. The cause of epiphora was determined based on patient history, clinical examination, and test results.</p><p><strong>Results: </strong>This study included 247 eyes from 159 patients, consisting of 57 (36%) males and 102 (64%) females. The mean age of the patients was 54.9 ± 15.57 years (range, 19-88 years). The duration of symptoms was 47.1 ± 28.0 months (range, 3-120 months). The most common cause of epiphora was nasolacrimal duct (NLD) obstruction found in 76 (30.7%) cases. Functional epiphora, found in 56 eyes (22.6%), was the second most common cause of epiphora. Reflex tearing was the cause of epiphora in 45 eyes (18.2%). Other causes of epiphora included eyelid malposition (in 40 eyes, 16.1%), multifactorial epiphora (in 24 eyes, 9.7%), and pre-sac obstruction (in 6 eyes, 2.4%). Functional epiphora was more common in females and often unilateral.</p><p><strong>Conclusion: </strong>Although NLD obstruction is the most common cause of epiphora, functional epiphora is a more frequent cause than previously anticipated. Observing complete patency in the lacrimal syringing is insufficient to rule out NLD stenosis and functional problems.</p>","PeriodicalId":13329,"journal":{"name":"Indian Journal of Ophthalmology","volume":"73 10","pages":"1432-1437"},"PeriodicalIF":1.8,"publicationDate":"2025-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145137265","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Comment on: Ocular biometric parameters in South-Indian children with myopia.","authors":"Divya Choudhary, Atanu Majumdar, Shailja Tibrewal","doi":"10.4103/IJO.IJO_564_25","DOIUrl":"https://doi.org/10.4103/IJO.IJO_564_25","url":null,"abstract":"","PeriodicalId":13329,"journal":{"name":"Indian Journal of Ophthalmology","volume":"73 10","pages":"1543"},"PeriodicalIF":1.8,"publicationDate":"2025-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145137401","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}