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Malaria a culprit of Gullian Barre Syndrome (GBS): A case report 疟疾是古利安-巴雷综合征（GBS）的罪魁祸首：一例报告。
IF 1.4 4区 医学
Indian Journal of Medical Microbiology Pub Date : 2025-03-15 DOI: 10.1016/j.ijmmb.2025.100824
Sara Soomro, Mehmood Alam, Hiba Akber, Sara Ismail, Lubna Iqbal Abbasi, Fivzia Farooq Herekar
{"title":"Malaria a culprit of Gullian Barre Syndrome (GBS): A case report","authors":"Sara Soomro,&nbsp;Mehmood Alam,&nbsp;Hiba Akber,&nbsp;Sara Ismail,&nbsp;Lubna Iqbal Abbasi,&nbsp;Fivzia Farooq Herekar","doi":"10.1016/j.ijmmb.2025.100824","DOIUrl":"10.1016/j.ijmmb.2025.100824","url":null,"abstract":"<div><div>Guillain-Barré Syndrome is an autoimmune condition that commonly develops after bacterial or viral infection. Parasitic infections including malaria can also rarely cause Guillain-Barré Syndrome especially in malaria endemic areas like Pakistan. The exact association between malaria and Guillain-Barré Syndrome is not well understood or documented in literature. We report a case of a young male who was infected with malaria due to Plasmodium falciparum and then developed Guillain-Barré Syndrome that was managed with plasmapheresis.</div></div>","PeriodicalId":13284,"journal":{"name":"Indian Journal of Medical Microbiology","volume":"55 ","pages":"Article 100824"},"PeriodicalIF":1.4,"publicationDate":"2025-03-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143648367","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Kimura disease with Nocardiosis in a child with a novel mutation in IL12RB1gene 一名患有新型 IL12RB1 基因突变的儿童患上木村病并伴有诺卡氏菌病。
IF 1.4 4区 医学
Indian Journal of Medical Microbiology Pub Date : 2025-03-01 DOI: 10.1016/j.ijmmb.2025.100816
Kranthikumar Karrolla , Gayatri Karuthapandy , Jaikumar Govindaswamy Ramamoorthy , Venkatesh Chandrasekaran , Gunasekaran Dhandapany , Maanasa Bhaskar , Mahalakshmi Kumaresan
{"title":"Kimura disease with Nocardiosis in a child with a novel mutation in IL12RB1gene","authors":"Kranthikumar Karrolla ,&nbsp;Gayatri Karuthapandy ,&nbsp;Jaikumar Govindaswamy Ramamoorthy ,&nbsp;Venkatesh Chandrasekaran ,&nbsp;Gunasekaran Dhandapany ,&nbsp;Maanasa Bhaskar ,&nbsp;Mahalakshmi Kumaresan","doi":"10.1016/j.ijmmb.2025.100816","DOIUrl":"10.1016/j.ijmmb.2025.100816","url":null,"abstract":"<div><div>A 12-year-old boy who had been diagnosed with Kimura disease was brought with a history suggestive of acute pyelonephritis. There was a family history of a first-degree relative with a diagnosis of Mendelian Susceptibility to Mycobacterial disease. Investigations revealed a left renal abscess. Aspirate culture grew <em>Nocardia otitidiscaviarum</em>. Targeted gene sequencing revealed a novel mutation in the IL12RB1 gene. Based on the above information a diagnosis of an underlying primary immune deficiency disorder was made. He was managed with appropriate antibiotics, showing steady improvement and eventually a complete recovery.</div></div>","PeriodicalId":13284,"journal":{"name":"Indian Journal of Medical Microbiology","volume":"54 ","pages":"Article 100816"},"PeriodicalIF":1.4,"publicationDate":"2025-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143531389","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Aims and Scope 目标及范围
IF 1.4 4区 医学
Indian Journal of Medical Microbiology Pub Date : 2025-03-01 DOI: 10.1016/S0255-0857(25)00051-9
{"title":"Aims and Scope","authors":"","doi":"10.1016/S0255-0857(25)00051-9","DOIUrl":"10.1016/S0255-0857(25)00051-9","url":null,"abstract":"","PeriodicalId":13284,"journal":{"name":"Indian Journal of Medical Microbiology","volume":"54 ","pages":"Article 100838"},"PeriodicalIF":1.4,"publicationDate":"2025-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144071287","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Short-term storage of Candida auris in resource-limited setting 资源有限条件下耳念珠菌的短期贮藏。
IF 1.4 4区 医学
Indian Journal of Medical Microbiology Pub Date : 2025-03-01 DOI: 10.1016/j.ijmmb.2025.100823
Yağmur Ekenoğlu Merdan, Kaan Zıkşahna
{"title":"Short-term storage of Candida auris in resource-limited setting","authors":"Yağmur Ekenoğlu Merdan,&nbsp;Kaan Zıkşahna","doi":"10.1016/j.ijmmb.2025.100823","DOIUrl":"10.1016/j.ijmmb.2025.100823","url":null,"abstract":"","PeriodicalId":13284,"journal":{"name":"Indian Journal of Medical Microbiology","volume":"54 ","pages":"Article 100823"},"PeriodicalIF":1.4,"publicationDate":"2025-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143639555","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Unleashing the potent synergy of ceftazidime-avibactam and aztreonam against metallo-beta-lactamase producing Enterobacterales in the battle against antibiotic resistance. An in vitro study 在对抗抗生素耐药性的战斗中释放头孢他啶-阿维巴坦和氨曲南对产生金属- β -内酰胺酶的肠杆菌的有效协同作用。体外研究
IF 1.4 4区 医学
Indian Journal of Medical Microbiology Pub Date : 2025-03-01 DOI: 10.1016/j.ijmmb.2025.100819
Madhu Rai , Shaoli Basu , Priti Kambli , Lizanne Drego , Priyanka Patel , Anjali Shetty , Camilla Rodrigues
{"title":"Unleashing the potent synergy of ceftazidime-avibactam and aztreonam against metallo-beta-lactamase producing Enterobacterales in the battle against antibiotic resistance. An in vitro study","authors":"Madhu Rai ,&nbsp;Shaoli Basu ,&nbsp;Priti Kambli ,&nbsp;Lizanne Drego ,&nbsp;Priyanka Patel ,&nbsp;Anjali Shetty ,&nbsp;Camilla Rodrigues","doi":"10.1016/j.ijmmb.2025.100819","DOIUrl":"10.1016/j.ijmmb.2025.100819","url":null,"abstract":"","PeriodicalId":13284,"journal":{"name":"Indian Journal of Medical Microbiology","volume":"54 ","pages":"Article 100819"},"PeriodicalIF":1.4,"publicationDate":"2025-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143580451","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Unveiling the uncommon: A rare case report of osteomyelitis caused by Enterococcus avium 揭开不常见的面纱：由肠球菌引起骨髓炎的罕见病例报告。
IF 1.4 4区 医学
Indian Journal of Medical Microbiology Pub Date : 2025-03-01 DOI: 10.1016/j.ijmmb.2025.100818
Priya Sreenivasan , Rishin Raj , J. Kumaravel , Deepak Kumar , Archana Angrup
{"title":"Unveiling the uncommon: A rare case report of osteomyelitis caused by Enterococcus avium","authors":"Priya Sreenivasan ,&nbsp;Rishin Raj ,&nbsp;J. Kumaravel ,&nbsp;Deepak Kumar ,&nbsp;Archana Angrup","doi":"10.1016/j.ijmmb.2025.100818","DOIUrl":"10.1016/j.ijmmb.2025.100818","url":null,"abstract":"<div><div>Osteomyelitis is an infection or inflammation of the bone. Infection of an intact bone is very rare, and osteomyelitis most often follows a fracture or surgery. <em>Staphylococcus aureus</em> is the most common organism implicated in cases of osteomyelitis. <em>Enterococcus</em> species are being increasingly reported worldwide for causing nosocomial and community-acquired infections. Despite a few reports of osteomyelitis by <em>Enterococcus faecalis</em> and <em>Enterococcus faecium,</em> osteomyelitis by <em>Enterococcus avium</em> is rarely reported in the literature. We hereby present a case of a 68-year-old male who presented with chronic osteomyelitis of the right tibia caused by <em>Enterococcus avium</em> with a successful outcome.</div></div>","PeriodicalId":13284,"journal":{"name":"Indian Journal of Medical Microbiology","volume":"54 ","pages":"Article 100818"},"PeriodicalIF":1.4,"publicationDate":"2025-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143673715","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Laboratory diagnosis of pleural tuberculosis: An unsolved enigma 胸膜结核的实验室诊断：一个未解之谜。
IF 1.4 4区 医学
Indian Journal of Medical Microbiology Pub Date : 2025-03-01 DOI: 10.1016/j.ijmmb.2025.100817
Atish Mohapatra , Ujjwala Gaikwad , Ranganath T. Ganga , Pratibha Sharma
{"title":"Laboratory diagnosis of pleural tuberculosis: An unsolved enigma","authors":"Atish Mohapatra ,&nbsp;Ujjwala Gaikwad ,&nbsp;Ranganath T. Ganga ,&nbsp;Pratibha Sharma","doi":"10.1016/j.ijmmb.2025.100817","DOIUrl":"10.1016/j.ijmmb.2025.100817","url":null,"abstract":"<div><h3>Background</h3><div>Pleural Tuberculosis (TB) diagnosis is challenging and the current diagnostic approach is multidisciplinary involving clinico-radiological methods in addition to laboratory parameters. The study aims to explore the role of all available parameters for pleural TB diagnosis.</div></div><div><h3>Methods</h3><div>A cross-sectional study on suspected pleural TB patients was conducted at a tertiary care hospital in Chhattisgarh from February to November 2021. After obtaining consent and clinico-radiological information, pleural fluid was collected and tested for biochemical profile and detection of <em>Mycobacterium tuberculosis</em> using available microbiological parameters.</div></div><div><h3>Results</h3><div>Out of 170 subjects, 26 had Definite TB (Microbiologically confirmed), 22 had Probable TB (clinico-radiologically confirmed), and 122 had No-TB. Necrotizing mediastinal lymphadenopathy, cervical lymphadenopathy &amp; loculated effusion were significant radiological findings. Amongst biochemical parameters, (Receiver Operating Characteristic (ROC) cut off 40.0 U/L; AUC = 0.889) of Adenosine Deaminase (ADA) was proved to be a better biomarker than LDH (ROC cut off 442.0 IU/L; AUC = 0.645). Out of all available microbiological parameters, Cartridge Based Nucleic Acid Amplification Test (CBNAAT) performed better by identifying (6/7; 85.71 %) pleural TB cases when compared against Microbiological Reference Standards (MRS). While compared against Composite Reference Standards (CRS), Mycobacteria Growth Indicator Tube (MGIT) performed better than other microbiological parameters by identifying (19/48; 39.5 %), while both CBNAAT and Truenat could identify (6/16; 37.5 %) and (12/32; 37.5 %) respectively.</div></div><div><h3>Conclusion</h3><div>In association with clinical and radiological features, ADA estimation is quite helpful in establishing or refuting the diagnosis of microbiologically negative pleural tuberculosis.</div></div>","PeriodicalId":13284,"journal":{"name":"Indian Journal of Medical Microbiology","volume":"54 ","pages":"Article 100817"},"PeriodicalIF":1.4,"publicationDate":"2025-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143541782","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Sebaceous nevus affected by overgrowth of Malassezia restricta 受马拉色菌过度生长影响的皮脂腺痣。
IF 1.4 4区 医学
Indian Journal of Medical Microbiology Pub Date : 2025-03-01 DOI: 10.1016/j.ijmmb.2025.100812
Ying Huang , Sushmita Pradhan , Yuping Ran
{"title":"Sebaceous nevus affected by overgrowth of Malassezia restricta","authors":"Ying Huang ,&nbsp;Sushmita Pradhan ,&nbsp;Yuping Ran","doi":"10.1016/j.ijmmb.2025.100812","DOIUrl":"10.1016/j.ijmmb.2025.100812","url":null,"abstract":"","PeriodicalId":13284,"journal":{"name":"Indian Journal of Medical Microbiology","volume":"54 ","pages":"Article 100812"},"PeriodicalIF":1.4,"publicationDate":"2025-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143491885","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Silent escalation: The journey of Shigella from gut to blood 无声升级：志贺氏菌从肠道到血液的旅程
IF 1.4 4区 医学
Indian Journal of Medical Microbiology Pub Date : 2025-03-01 DOI: 10.1016/j.ijmmb.2025.100815
Ekadashi Rajni , Snigdha Purohit , Rachna Priyadarshini , Gunjan Agarwal
{"title":"Silent escalation: The journey of Shigella from gut to blood","authors":"Ekadashi Rajni ,&nbsp;Snigdha Purohit ,&nbsp;Rachna Priyadarshini ,&nbsp;Gunjan Agarwal","doi":"10.1016/j.ijmmb.2025.100815","DOIUrl":"10.1016/j.ijmmb.2025.100815","url":null,"abstract":"<div><div><em>Shigella</em> are Gram-negative non motile facultative anaerobic bacteria belonging to family <em>Enterobacterales</em>. They are a leading cause of diarrhoea and dysentery and constitute a significant public health problem in both the developing and developed nations. In Asia alone, 125 million infections and 14,000 deaths are estimated to be due to shigellosis annually. Bacteremia caused by <em>Shigella</em> spp is rare. We hereby present a case of bloodstream infection caused by fluoroquinolone resistant, extended spectrum beta lactamase producing <em>Shigella flexneri</em> strain in a five-year-old malnourished child that was successfully managed using meropenem and supportive treatment.</div></div>","PeriodicalId":13284,"journal":{"name":"Indian Journal of Medical Microbiology","volume":"54 ","pages":"Article 100815"},"PeriodicalIF":1.4,"publicationDate":"2025-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143580452","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Association of ALS genes in strains of the genus Candida with cervical cytological alterations 念珠菌属ALS基因与宫颈细胞学改变的关系
IF 1.4 4区 医学
Indian Journal of Medical Microbiology Pub Date : 2025-03-01 DOI: 10.1016/j.ijmmb.2025.100795
J.L. Ibáñez-Cervantes , Cruz Vargas-de León , J.M. Veléz-Reséndiz , V. Fernández-Sánchez , R. Saavedra-Bravo , C. Bandala , I. Olvera-Gómez , J. Mancilla-Ramírez , G. Ibáñez-Cervantes
{"title":"Association of ALS genes in strains of the genus Candida with cervical cytological alterations","authors":"J.L. Ibáñez-Cervantes ,&nbsp;Cruz Vargas-de León ,&nbsp;J.M. Veléz-Reséndiz ,&nbsp;V. Fernández-Sánchez ,&nbsp;R. Saavedra-Bravo ,&nbsp;C. Bandala ,&nbsp;I. Olvera-Gómez ,&nbsp;J. Mancilla-Ramírez ,&nbsp;G. Ibáñez-Cervantes","doi":"10.1016/j.ijmmb.2025.100795","DOIUrl":"10.1016/j.ijmmb.2025.100795","url":null,"abstract":"<div><h3>Purpose</h3><div>Fungi are an important cause of human infection and include infections caused by <em>Candida</em> species. Vaginal candidiasis is a mycosis caused by several species of the genus <em>Candida</em>. In Mexico, it is considered the only mycosis that must be reported to health authorities. The participation and/or contribution of <em>Candida</em> ALS genes to the presence of cervical cytological alterations is currently unknown. The purpose of this study was to elucidate the frequency of <em>Candida</em> ALS genes and their association with clinical characteristics.</div></div><div><h3>Methods</h3><div>The number of randomly selected samples was 697, of which 53 were <em>Candida</em> positive. Samples were selected from women attending gynaecological outpatient clinics for cervical cancer screening at <em>Hospital Juarez de Mexico</em>. These strains were identified, and genomic DNA was obtained from each isolate. Molecular assays were performed by endpoint PCR amplification of ALS genes.</div></div><div><h3>Results</h3><div>The predominant <em>Candida</em> species identified in the study were <em>Candida tropicalis</em> and <em>Candida albicans</em>. ALS1 12 (22.6 %) and ALS3 19 (35.8 %) genes were found. ALS2, ALS4, ALS5, ALS6, ALS7, and ALS9 genes were not detected. ALS1 was the gene that was associated with patients using corticosteroids.</div></div><div><h3>Conclusions</h3><div>Vulvovaginitis remains one of the most prevalent conditions in patients in their 20s and 30s, and it is a real public health problem. Further studies are needed to determine the direct involvement of the identified ALS genes in the pathogen's ability to adhere and how it causes transient change in vaginal cytology.</div></div>","PeriodicalId":13284,"journal":{"name":"Indian Journal of Medical Microbiology","volume":"54 ","pages":"Article 100795"},"PeriodicalIF":1.4,"publicationDate":"2025-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144071176","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
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