{"title":"成人皮肤白喉的非毒性菌株:病例报告和文献复习","authors":"Khyati , Benu Dhawan , Vikas Gautam , Nishant Shekhar , Neetu Bhari , Jaya Biswas , Pranav Rai , Ritika Dhakad , Bimal Kumar Das","doi":"10.1016/j.ijmmb.2025.100892","DOIUrl":null,"url":null,"abstract":"<div><div>We report an unusual case of recurrently infected post-folliculitis keloid. The diagnosis of cutaneous diphtheria was made by isolation of <em>Corynebacterium diphtheriae</em> cultured from pus collected from the skin lesion. The strain was non-toxigenic on multiplex real-time PCR assay. A prior pus sample from the lesion had grown Methicillin resistant <em>Staphylococcus aureus</em> (MRSA). The patient was treated with oral erythromycin for 14-days. Chemoprophylaxis was advised to the close contacts. The present case emphasizes the importance of investigation for unusual etiologies in patients with non-responding ulcerative cutaneous lesions. Early diagnosis of cutaneous diphtheria is required for appropriate treatment and effective control measures.</div></div>","PeriodicalId":13284,"journal":{"name":"Indian Journal of Medical Microbiology","volume":"56 ","pages":"Article 100892"},"PeriodicalIF":1.4000,"publicationDate":"2025-06-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":"{\"title\":\"Adult cutaneous diphtheria by non-toxicogenic strain: Case report and review of literature\",\"authors\":\"Khyati , Benu Dhawan , Vikas Gautam , Nishant Shekhar , Neetu Bhari , Jaya Biswas , Pranav Rai , Ritika Dhakad , Bimal Kumar Das\",\"doi\":\"10.1016/j.ijmmb.2025.100892\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<div><div>We report an unusual case of recurrently infected post-folliculitis keloid. The diagnosis of cutaneous diphtheria was made by isolation of <em>Corynebacterium diphtheriae</em> cultured from pus collected from the skin lesion. The strain was non-toxigenic on multiplex real-time PCR assay. A prior pus sample from the lesion had grown Methicillin resistant <em>Staphylococcus aureus</em> (MRSA). The patient was treated with oral erythromycin for 14-days. Chemoprophylaxis was advised to the close contacts. The present case emphasizes the importance of investigation for unusual etiologies in patients with non-responding ulcerative cutaneous lesions. Early diagnosis of cutaneous diphtheria is required for appropriate treatment and effective control measures.</div></div>\",\"PeriodicalId\":13284,\"journal\":{\"name\":\"Indian Journal of Medical Microbiology\",\"volume\":\"56 \",\"pages\":\"Article 100892\"},\"PeriodicalIF\":1.4000,\"publicationDate\":\"2025-06-07\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Indian Journal of Medical Microbiology\",\"FirstCategoryId\":\"3\",\"ListUrlMain\":\"https://www.sciencedirect.com/science/article/pii/S0255085725001057\",\"RegionNum\":4,\"RegionCategory\":\"医学\",\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"Q4\",\"JCRName\":\"IMMUNOLOGY\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Indian Journal of Medical Microbiology","FirstCategoryId":"3","ListUrlMain":"https://www.sciencedirect.com/science/article/pii/S0255085725001057","RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q4","JCRName":"IMMUNOLOGY","Score":null,"Total":0}
Adult cutaneous diphtheria by non-toxicogenic strain: Case report and review of literature
We report an unusual case of recurrently infected post-folliculitis keloid. The diagnosis of cutaneous diphtheria was made by isolation of Corynebacterium diphtheriae cultured from pus collected from the skin lesion. The strain was non-toxigenic on multiplex real-time PCR assay. A prior pus sample from the lesion had grown Methicillin resistant Staphylococcus aureus (MRSA). The patient was treated with oral erythromycin for 14-days. Chemoprophylaxis was advised to the close contacts. The present case emphasizes the importance of investigation for unusual etiologies in patients with non-responding ulcerative cutaneous lesions. Early diagnosis of cutaneous diphtheria is required for appropriate treatment and effective control measures.
期刊介绍:
Manuscripts of high standard in the form of original research, multicentric studies, meta analysis, are accepted. Current reports can be submitted as brief communications. Case reports must include review of current literature, clinical details, outcome and follow up. Letters to the editor must be a comment on or pertain to a manuscript already published in the IJMM or in relation to preliminary communication of a larger study.
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