成人皮肤白喉的非毒性菌株:病例报告和文献复习

IF 1.4 4区 医学 Q4 IMMUNOLOGY
Khyati , Benu Dhawan , Vikas Gautam , Nishant Shekhar , Neetu Bhari , Jaya Biswas , Pranav Rai , Ritika Dhakad , Bimal Kumar Das
{"title":"成人皮肤白喉的非毒性菌株:病例报告和文献复习","authors":"Khyati ,&nbsp;Benu Dhawan ,&nbsp;Vikas Gautam ,&nbsp;Nishant Shekhar ,&nbsp;Neetu Bhari ,&nbsp;Jaya Biswas ,&nbsp;Pranav Rai ,&nbsp;Ritika Dhakad ,&nbsp;Bimal Kumar Das","doi":"10.1016/j.ijmmb.2025.100892","DOIUrl":null,"url":null,"abstract":"<div><div>We report an unusual case of recurrently infected post-folliculitis keloid. The diagnosis of cutaneous diphtheria was made by isolation of <em>Corynebacterium diphtheriae</em> cultured from pus collected from the skin lesion. The strain was non-toxigenic on multiplex real-time PCR assay. A prior pus sample from the lesion had grown Methicillin resistant <em>Staphylococcus aureus</em> (MRSA). The patient was treated with oral erythromycin for 14-days. Chemoprophylaxis was advised to the close contacts. The present case emphasizes the importance of investigation for unusual etiologies in patients with non-responding ulcerative cutaneous lesions. Early diagnosis of cutaneous diphtheria is required for appropriate treatment and effective control measures.</div></div>","PeriodicalId":13284,"journal":{"name":"Indian Journal of Medical Microbiology","volume":"56 ","pages":"Article 100892"},"PeriodicalIF":1.4000,"publicationDate":"2025-06-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":"{\"title\":\"Adult cutaneous diphtheria by non-toxicogenic strain: Case report and review of literature\",\"authors\":\"Khyati ,&nbsp;Benu Dhawan ,&nbsp;Vikas Gautam ,&nbsp;Nishant Shekhar ,&nbsp;Neetu Bhari ,&nbsp;Jaya Biswas ,&nbsp;Pranav Rai ,&nbsp;Ritika Dhakad ,&nbsp;Bimal Kumar Das\",\"doi\":\"10.1016/j.ijmmb.2025.100892\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<div><div>We report an unusual case of recurrently infected post-folliculitis keloid. The diagnosis of cutaneous diphtheria was made by isolation of <em>Corynebacterium diphtheriae</em> cultured from pus collected from the skin lesion. The strain was non-toxigenic on multiplex real-time PCR assay. A prior pus sample from the lesion had grown Methicillin resistant <em>Staphylococcus aureus</em> (MRSA). The patient was treated with oral erythromycin for 14-days. Chemoprophylaxis was advised to the close contacts. The present case emphasizes the importance of investigation for unusual etiologies in patients with non-responding ulcerative cutaneous lesions. Early diagnosis of cutaneous diphtheria is required for appropriate treatment and effective control measures.</div></div>\",\"PeriodicalId\":13284,\"journal\":{\"name\":\"Indian Journal of Medical Microbiology\",\"volume\":\"56 \",\"pages\":\"Article 100892\"},\"PeriodicalIF\":1.4000,\"publicationDate\":\"2025-06-07\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Indian Journal of Medical Microbiology\",\"FirstCategoryId\":\"3\",\"ListUrlMain\":\"https://www.sciencedirect.com/science/article/pii/S0255085725001057\",\"RegionNum\":4,\"RegionCategory\":\"医学\",\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"Q4\",\"JCRName\":\"IMMUNOLOGY\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Indian Journal of Medical Microbiology","FirstCategoryId":"3","ListUrlMain":"https://www.sciencedirect.com/science/article/pii/S0255085725001057","RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q4","JCRName":"IMMUNOLOGY","Score":null,"Total":0}
引用次数: 0

摘要

我们报告一个不寻常的病例反复感染后毛囊炎瘢痕疙瘩。从皮肤病变处收集的脓液中分离出白喉棒状杆菌,诊断为皮肤白喉。多重实时荧光定量PCR检测该菌株不产毒。先前的脓液样本已经生长出耐甲氧西林金黄色葡萄球菌(MRSA)。患者口服红霉素治疗14 d。建议密切接触者进行化学预防。本病例强调了对无反应性溃疡性皮肤病变患者的异常病因进行调查的重要性。皮肤白喉需要早期诊断,以便采取适当的治疗和有效的控制措施。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Adult cutaneous diphtheria by non-toxicogenic strain: Case report and review of literature
We report an unusual case of recurrently infected post-folliculitis keloid. The diagnosis of cutaneous diphtheria was made by isolation of Corynebacterium diphtheriae cultured from pus collected from the skin lesion. The strain was non-toxigenic on multiplex real-time PCR assay. A prior pus sample from the lesion had grown Methicillin resistant Staphylococcus aureus (MRSA). The patient was treated with oral erythromycin for 14-days. Chemoprophylaxis was advised to the close contacts. The present case emphasizes the importance of investigation for unusual etiologies in patients with non-responding ulcerative cutaneous lesions. Early diagnosis of cutaneous diphtheria is required for appropriate treatment and effective control measures.
求助全文
通过发布文献求助,成功后即可免费获取论文全文。 去求助
来源期刊
CiteScore
2.20
自引率
0.00%
发文量
154
审稿时长
73 days
期刊介绍: Manuscripts of high standard in the form of original research, multicentric studies, meta analysis, are accepted. Current reports can be submitted as brief communications. Case reports must include review of current literature, clinical details, outcome and follow up. Letters to the editor must be a comment on or pertain to a manuscript already published in the IJMM or in relation to preliminary communication of a larger study. Review articles, Special Articles or Guest Editorials are accepted on invitation.
×
引用
GB/T 7714-2015
复制
MLA
复制
APA
复制
导出至
BibTeX EndNote RefMan NoteFirst NoteExpress
×
提示
您的信息不完整,为了账户安全,请先补充。
现在去补充
×
提示
您因"违规操作"
具体请查看互助需知
我知道了
×
提示
确定
请完成安全验证×
copy
已复制链接
快去分享给好友吧!
我知道了
右上角分享
点击右上角分享
0
联系我们:info@booksci.cn Book学术提供免费学术资源搜索服务,方便国内外学者检索中英文文献。致力于提供最便捷和优质的服务体验。 Copyright © 2023 布克学术 All rights reserved.
京ICP备2023020795号-1
ghs 京公网安备 11010802042870号
Book学术文献互助
Book学术文献互助群
群 号:604180095
Book学术官方微信