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IEEE Transactions on NanoBioscience Publication Information 电气和电子工程师学会《纳米生物科学论文集》出版信息

IF 3.9 4区生物学

IEEE Transactions on NanoBioscience Pub Date : 2024-01-03 DOI: 10.1109/TNB.2023.3345596

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IEEE Transactions on NanoBioscience Information for Authors 电气和电子工程师学会《纳米生物科学学报》为作者提供的信息

IF 3.9 4区生物学

IEEE Transactions on NanoBioscience Pub Date : 2024-01-03 DOI: 10.1109/TNB.2023.3345600

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CRISPR-Enabled Graphene-Based Bio-Cyber Interface Model for In Vivo Monitoring of Non-Invasive Therapeutic Processes 基于石墨烯的 CRISPR 生物网络接口模型，用于体内监测非侵入性治疗过程。

IF 3.9 4区生物学

IEEE Transactions on NanoBioscience Pub Date : 2023-12-29 DOI: 10.1109/TNB.2023.3348201

Uche A. K. Chude-Okonkwo;Athanasios V. Vasilakos

{"title":"CRISPR-Enabled Graphene-Based Bio-Cyber Interface Model for In Vivo Monitoring of Non-Invasive Therapeutic Processes","authors":"Uche A. K. Chude-Okonkwo;Athanasios V. Vasilakos","doi":"10.1109/TNB.2023.3348201","DOIUrl":"10.1109/TNB.2023.3348201","url":null,"abstract":"In this paper, we present a model of the bio-cyber interface for the Internet of Bio-Nano Things application. The proposed model is inspired by the gains of integrating the Clustered Regularly Interspace Short Palindromic Repeats (CRISPR) technology with the Graphene-Field effect transistor (GFET). The capabilities of the integrated system are harnessed to detect nucleic acids transcribed by another component of the bio-cyber interface, a bioreporter, on being exposed to the signalling molecule of interest. The proposed model offers a label-free real-time signal transduction with multi-symbol signalling capability. We model the entire operation of the interface as a set of simultaneous differential equations representing the process’s kinetics. The solution to the model is obtained using a numerical method. Numerical results show that the performance of the interface is influenced by parameters such as the concentrations of the input signalling molecules, the surface receptor on the bioreporter, and the CRISPR complex. The interface’s performance also depends considerably on the elimination rate of the signalling molecules from the body. For multi-symbol molecular signalling, the rate of degradation of the transcribed RNAs influences the system’s susceptibility to inter-symbol interference.","PeriodicalId":13264,"journal":{"name":"IEEE Transactions on NanoBioscience","volume":"23 2","pages":"300-309"},"PeriodicalIF":3.9,"publicationDate":"2023-12-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139073911","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"生物学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

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COVID-19 Detection Using Contemporary Biosensors and Machine Learning Approach: A Review 使用当代生物传感器和机器学习方法检测 COVID-19：综述。

IF 3.9 4区生物学

IEEE Transactions on NanoBioscience Pub Date : 2023-12-13 DOI: 10.1109/TNB.2023.3342126

Sajal Agarwal;Rupam Srivastava;Santosh Kumar;Yogendra Kumar Prajapati

引用次数: 0

Design and Analysis of MEMS Pressure Sensor based on various principles of Microcantilever beam. 基于微悬臂梁的各种原理设计和分析 MEMS 压力传感器。

IF 3.9 4区生物学

IEEE Transactions on NanoBioscience Pub Date : 2023-12-12 DOI: 10.1109/TNB.2023.3334749

G Sai Lakshmai, K Srinivasa Rao, K Girija Sravani

{"title":"Design and Analysis of MEMS Pressure Sensor based on various principles of Microcantilever beam.","authors":"G Sai Lakshmai, K Srinivasa Rao, K Girija Sravani","doi":"10.1109/TNB.2023.3334749","DOIUrl":"https://doi.org/10.1109/TNB.2023.3334749","url":null,"abstract":"<p><p>In this paper, we have used COMSOL Multiphysics for the design and simulation of three different micro cantilever configurations. These micro cantilevers are analyzed using finite element analysis (FEM) to understand their mechanical behavior, sensitivity, and non-linear characteristics. The goal of the research is to identify the most suitable micro cantilever design for integration with an electro-osmotic pressure sensor. This integrated system is intended to measure variations in glucose concentration levels with accuracy and efficiency, with potential applications in glucose monitoring and biomedical fields. The sensitivity of the microcantilever is reported as 0.10e-7. The stress value is given as 1.64. A change in resistance of 0.00011 Ω·μm is mentioned. The reported output voltage is 0.15 μV. This voltage is likely generated by the microcantilever in response to the changes in resistance, which are in turn caused by variations in glucose concentration. The gauge factor is given as 0.04. The gauge factor is a measure of the sensitivity of a strain gauge (in this case, the microcantilever) and is often used to relate the mechanical strain (stress) to the electrical resistance change. These parameters provide insights into the performance of the microcantilever-based glucose sensor and its ability to detect glucose concentration variations. The small output voltage indicates the need for sensitive detection and measurement equipment to utilize the sensor effectively.</p>","PeriodicalId":13264,"journal":{"name":"IEEE Transactions on NanoBioscience","volume":"PP ","pages":""},"PeriodicalIF":3.9,"publicationDate":"2023-12-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"138802130","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"生物学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Design and Fabrication of Enzymatic Potentiometric Biosensor Based on Flexible Printed Circuit Board for Glucose Detection 基于柔性印刷电路板的葡萄糖酶电位生物传感器的设计与制造。

IF 3.9 4区生物学

IEEE Transactions on NanoBioscience Pub Date : 2023-11-28 DOI: 10.1109/TNB.2023.3337381

Po-Yu Kuo;Chi-Han Liao;Tai-Hui Wang;Ming-Tai Hsu

{"title":"Design and Fabrication of Enzymatic Potentiometric Biosensor Based on Flexible Printed Circuit Board for Glucose Detection","authors":"Po-Yu Kuo;Chi-Han Liao;Tai-Hui Wang;Ming-Tai Hsu","doi":"10.1109/TNB.2023.3337381","DOIUrl":"10.1109/TNB.2023.3337381","url":null,"abstract":"This study investigated the development and optimization of a flexible printed circuit board-based glucose biosensor with an emphasis on high sensitivity, selectivity, and overall performance. Advances in glucose biosensing have highlighted its importance in medical diagnostics, especially diabetes management. The fabrication process involves depositing a RuO2 sensing film on a flexible printed circuit board (FPCB) by radio frequency sputtering. Enzyme-based modification using glucose oxidase (GOx), (3-aminopropyl) triethoxysilane (APTES), and glutaraldehyde (GA) to enhance selectivity and catalytic reactions. And through Scanning Electron Microscopy and electrochemical impedance spectroscopy, the sensing film, and the effect of modification on the charge transfer rate and performance improvement were analyzed. This glucose biosensor has excellent linearity, sensitivity, and reproducibility. The study also assessed response time and selectivity. The response time efficiency of the biosensor solidified its utility in point-of-care monitoring, while selectivity experiments validated its ability to distinguish glucose from interfering substances, ensuring accuracy in practical applications. According to the experimental results, the enzymatic glucose biosensor has the best average sensitivity and linearity of 44.42 mV/mM and 0.999 with a response time of 6 seconds.","PeriodicalId":13264,"journal":{"name":"IEEE Transactions on NanoBioscience","volume":"23 2","pages":"283-290"},"PeriodicalIF":3.9,"publicationDate":"2023-11-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"138451404","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"生物学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

On Secrecy Performance in D-MoSK-Based 3-D Diffusive Molecular Communication System 基于D-MoSK的三维扩散分子通信系统的保密性能研究。

IF 3.9 4区生物学

IEEE Transactions on NanoBioscience Pub Date : 2023-10-04 DOI: 10.1109/TNB.2023.3321790

Zhen Jia;Lisheng Ma;Shigen Shen;Xiaohong Jiang

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2023 Index IEEE Transactions on NanoBioscience Vol. 22 《纳米生物科学学报》第22卷

IF 3.9 4区生物学

IEEE Transactions on NanoBioscience Pub Date : 2023-10-04 DOI: 10.1109/TNB.2023.3322178

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IEEE Transactions on NanoBioscience Publication Information IEEE纳米生物科学学报

IF 3.9 4区生物学

IEEE Transactions on NanoBioscience Pub Date : 2023-10-03 DOI: 10.1109/TNB.2023.3316414

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IEEE Transactions on NanoBioscience Information for Authors IEEE纳米生物科学信息汇刊

IF 3.9 4区生物学

IEEE Transactions on NanoBioscience Pub Date : 2023-10-03 DOI: 10.1109/TNB.2023.3316418

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