IEEE Transactions on NanoBioscience最新文献_第10页

Microfluidic Point-of-Care Diagnostics for Multi-Disease Detection Using Optical Techniques: A Review 利用光学技术进行多种疾病检测的微流控医疗点诊断：综述。

IF 3.9 4区生物学

IEEE Transactions on NanoBioscience Pub Date : 2023-07-03 DOI: 10.1109/TNB.2023.3291544

Shaik Ahmadsaidulu;Oindrila Banik;Prasoon Kumar;Santosh Kumar;Earu Banoth

{"title":"Microfluidic Point-of-Care Diagnostics for Multi-Disease Detection Using Optical Techniques: A Review","authors":"Shaik Ahmadsaidulu;Oindrila Banik;Prasoon Kumar;Santosh Kumar;Earu Banoth","doi":"10.1109/TNB.2023.3291544","DOIUrl":"10.1109/TNB.2023.3291544","url":null,"abstract":"The lifestyle of modern society is a major contributing factor for the majority of patients suffering from more than one disease. To Screen and diagnose each of those diseases, there is a great need for portable, and economical diagnostic tools, which are highly stipulated to yield rapid and accurate results using a small volume of the samples such as blood, saliva, sweat, etc. Point-of-care Testing (POCT) is one of the approaches to harvest prompt diagnosis of numerous diseases. The Majority of Point-of-Care Devices (POCD) are developed to diagnose one disease within the specimen. On the other hand, multi-disease detection capabilities in the same point-of-care devices are considered to be an efficient candidate to execute the state-of-the-art platform for multi-disease detection. Most of the literature reviews in this field focus on Point-of-Care (POC) devices, their underlying principles of operation, and their potential applications. It is evident from a perusal of the scholarly works that no review articles have been written on multi-disease detection POC devices. A review study analyzing the current level and functionality of multi-disease detection POC devices would be of great use to future researchers and device manufacturers. This review paper is addressing the above gap by focusing on various optical techniques like fluorescence, Absorbance, and Surface Plasmon Resonance (SPR) for multi-disease detection by harnessing the microfluidic-based POC device.","PeriodicalId":13264,"journal":{"name":"IEEE Transactions on NanoBioscience","volume":"23 1","pages":"140-147"},"PeriodicalIF":3.9,"publicationDate":"2023-07-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"9747538","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"生物学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

IEEE Transactions on NanoBioscience Publication Information IEEE纳米生物科学学报

IF 3.9 4区生物学

IEEE Transactions on NanoBioscience Pub Date : 2023-06-29 DOI: 10.1109/TNB.2023.3283631

引用次数: 0

IEEE Transactions on NanoBioscience Information for Authors IEEE纳米生物科学信息汇刊

IF 3.9 4区生物学

IEEE Transactions on NanoBioscience Pub Date : 2023-06-29 DOI: 10.1109/TNB.2023.3283635

引用次数: 0

Biosynthesis of Gold Nanoparticles Using Quince Seed Water Extract and Investigation of Their Anticancer Effect Against Cancer Cell Lines 利用榅桲籽水提取物生物合成金纳米粒子并研究其对癌症细胞株的抗癌效果

IF 3.9 4区生物学

IEEE Transactions on NanoBioscience Pub Date : 2023-06-28 DOI: 10.1109/TNB.2023.3287805

Mohammad Reza Ahmadpour;Mahdi Yousefi;Hassan Rakhshandeh;Majid Darroudi;Seyed Hadi Mousavi;Mohammad Soukhtanloo;Zahra Sabouri;Vahid Reza Askari;Alireza Hashemzadeh;Mohammad Azad Manjiri;Malihe Motavasselian

引用次数: 0

Optimization of Extracellular Vesicle Release for Targeted Drug Delivery 优化细胞外囊泡释放，实现靶向给药。

IF 3.9 4区生物学

IEEE Transactions on NanoBioscience Pub Date : 2023-06-19 DOI: 10.1109/TNB.2023.3287637

Martin Damrath;Mladen Veletić;Hamid Khoshfekr Rudsari;Ilangko Balasingham

引用次数: 0

Review of Physical Layer Security in Molecular Internet of Nano-Things 纳米物联网中的物理层安全回顾。

IF 3.9 4区生物学

IEEE Transactions on NanoBioscience Pub Date : 2023-06-14 DOI: 10.1109/TNB.2023.3285973

Song Qiu;Zhuangkun Wei;Yu Huang;Mahmoud Abbaszadeh;Jerome Charmet;Bin Li;Weisi Guo

{"title":"Review of Physical Layer Security in Molecular Internet of Nano-Things","authors":"Song Qiu;Zhuangkun Wei;Yu Huang;Mahmoud Abbaszadeh;Jerome Charmet;Bin Li;Weisi Guo","doi":"10.1109/TNB.2023.3285973","DOIUrl":"10.1109/TNB.2023.3285973","url":null,"abstract":"Molecular networking has been identified as a key enabling technology for Internet-of-Nano-Things (IoNT): microscopic devices that can monitor, process information, and take action in a wide range of medical applications. As the research matures into prototypes, the cybersecurity challenges of molecular networking are now being researched on at both the cryptographic and physical layer level. Due to the limited computation capabilities of IoNT devices, physical layer security (PLS) is of particular interest. As PLS leverages on channel physics and physical signal attributes, the fact that molecular signals differ significantly from radio frequency signals and propagation means new signal processing methods and hardware is needed. Here, we review new vectors of attack and new methods of PLS, focusing on 3 areas: (1) information theoretical secrecy bounds for molecular communications, (2) key-less steering and decentralized key-based PLS methods, and (3) new methods of achieving encoding and encryption through bio-molecular compounds. The review will also include prototype demonstrations from our own lab that will inform future research and related standardization efforts.","PeriodicalId":13264,"journal":{"name":"IEEE Transactions on NanoBioscience","volume":"23 1","pages":"91-100"},"PeriodicalIF":3.9,"publicationDate":"2023-06-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"10005367","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"生物学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 1

Multi-Disease Detection Using a Prism-Based Surface Plasmon Resonance Sensor: A TMM and FEM Approach 使用棱镜式表面等离子体共振传感器检测多种疾病：TMM 和有限元方法

IF 3.9 4区生物学

IEEE Transactions on NanoBioscience Pub Date : 2023-06-14 DOI: 10.1109/TNB.2023.3286269

Rabeya Bosrin Rumi;Alok Kumar Paul;Salem A. Alyami;Mohammad Ali Moni

{"title":"Multi-Disease Detection Using a Prism-Based Surface Plasmon Resonance Sensor: A TMM and FEM Approach","authors":"Rabeya Bosrin Rumi;Alok Kumar Paul;Salem A. Alyami;Mohammad Ali Moni","doi":"10.1109/TNB.2023.3286269","DOIUrl":"10.1109/TNB.2023.3286269","url":null,"abstract":"This research introduces a surface plasmon resonance (SPR)-based biosensor with multilayered structures for telecommunication wavelength in order to detect multiple diseases. The malaria and the chikungunya viruses are taken into account and the presence of these viruses are determined by examining several blood components in healthy and affected phases. Here, two distinct configurations (Al-BTO-Al-MoS2 and Cu-BTO-Cu-MoS2) are proposed and contrasted for the detection of numerous viruses. The performance characteristics of this work have been analyzed using Transfer Matrix Method (TMM) method and Finite Element Method (FEM) method under angle interrogation technique. From the TMM and FEM solutions, it is evident that the Al-BTO-Al-MoS2 structure provides the highest sensitivities of ~270 deg./RIU for malaria and ~262 deg./RIU for chikungunya viruses, with satisfactory detection accuracy of ~1.10 for malaria, ~1.64 for chikungunya, and quality factor of ~204.40 for malaria, ~208.20 for chikungunya. In addition, the Cu-BTO-Cu MoS2 structure offers the highest sensitivities of ~310 deg./RIU for malaria and ~298 deg./RIU for chikungunya, with satisfactory detection accuracy of ~0.40 for malaria, ~0.58 for chikungunya, and quality factor of ~89.85 for malaria, ~86.38 for chikungunya viruses. Therefore, the performance of the proposed sensors is analyzed using two distinct methods and gives around similar results. In a sum, this research could be utilized as a theoretical foundation and first step in the development of a real sensor.","PeriodicalId":13264,"journal":{"name":"IEEE Transactions on NanoBioscience","volume":"23 1","pages":"51-62"},"PeriodicalIF":3.9,"publicationDate":"2023-06-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"9853795","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"生物学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Modeling Extracellular Vesicles-Mediated Interactions of Cells in the Tumor Microenvironment 模拟细胞外囊泡介导的肿瘤微环境中细胞的相互作用

IF 3.9 4区生物学

IEEE Transactions on NanoBioscience Pub Date : 2023-06-12 DOI: 10.1109/TNB.2023.3284090

Mohammad Zoofaghari;Fabrizio Pappalardo;Martin Damrath;Ilangko Balasingham

{"title":"Modeling Extracellular Vesicles-Mediated Interactions of Cells in the Tumor Microenvironment","authors":"Mohammad Zoofaghari;Fabrizio Pappalardo;Martin Damrath;Ilangko Balasingham","doi":"10.1109/TNB.2023.3284090","DOIUrl":"10.1109/TNB.2023.3284090","url":null,"abstract":"Interactions of cells via extracellular vesicles (EVs) manipulate various actions, including cancer initiation and progression, inflammation, anti-tumor signaling and cell migration, proliferation and apoptosis in the tumor microenvironment. EVs as the external stimulus can activate or inhibit some receptor pathways in a way that amplify or attenuate a kind of particle release at target cells. This can also be carried out in a biological feedback-loop where the transmitter is affected by the induced release initiated by the target cell due to the EVs received from the donor cell, to create a bilateral process. In this paper, at first we derive the frequency response of internalization function in the framework of a unilateral communication link. This solution is adapted to a closed-loop system to find the frequency response of a bilateral system. The overall releases of the cells, given by the combination of the natural release and the induced release, are reported at the end of this paper and the results are compared in terms of distance between the cells and reaction rates of EVs at the cell membranes.","PeriodicalId":13264,"journal":{"name":"IEEE Transactions on NanoBioscience","volume":"23 1","pages":"71-80"},"PeriodicalIF":3.9,"publicationDate":"2023-06-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"9680469","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"生物学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Timed Tissue P Systems With Channel States 具有通道状态的定时组织 P 系统

IF 3.9 4区生物学

IEEE Transactions on NanoBioscience Pub Date : 2023-06-12 DOI: 10.1109/TNB.2023.3278653

Yueguo Luo;Yuzhen Zhao;Yi Liu

{"title":"Timed Tissue P Systems With Channel States","authors":"Yueguo Luo;Yuzhen Zhao;Yi Liu","doi":"10.1109/TNB.2023.3278653","DOIUrl":"10.1109/TNB.2023.3278653","url":null,"abstract":"Tissue P systems with channel states are a variant of tissue P systems that can be employed as highly parallel computing devices, where the channel states can control the movements of objects. In a sense, the time-free approach can improve the robustness of P systems; hence, in this work, we introduce the time-free property into such P systems and explore their computational performances. Specifically, in a time-free manner, it is proved that this type of P systems have Turing universality by using two cells and four channel states with a maximum rule length of 2, or by using two cells and noncooperative symport rules with a maximum rule length of 1. Moreover, in terms of computational efficiency, it is proved that a uniform solution of the satisfiability (\u0000<inline-formula> <tex-math>$mathcal {SAT}$ </tex-math></inline-formula>\u0000) problem can be obtained in a time-free manner by applying noncooperative symport rules with a maximum rule length of 1. The research results of this paper show that a highly robust dynamic membrane computing system is constructed. Theoretically, relative to the existing system, our constructed system can enhance robustness and expand its application scope.","PeriodicalId":13264,"journal":{"name":"IEEE Transactions on NanoBioscience","volume":"23 1","pages":"26-34"},"PeriodicalIF":3.9,"publicationDate":"2023-06-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"9675270","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"生物学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Iterative Soft Decoding Algorithm for DNA Storage Using Quality Score and Redecoding 利用质量分数和重编码的 DNA 存储迭代软解码算法

IF 3.9 4区生物学

IEEE Transactions on NanoBioscience Pub Date : 2023-06-09 DOI: 10.1109/TNB.2023.3284406

Jaeho Jeong;Hosung Park;Hee-Youl Kwak;Jong-Seon No;Hahyeon Jeon;Jeong Wook Lee;Jae-Won Kim

{"title":"Iterative Soft Decoding Algorithm for DNA Storage Using Quality Score and Redecoding","authors":"Jaeho Jeong;Hosung Park;Hee-Youl Kwak;Jong-Seon No;Hahyeon Jeon;Jeong Wook Lee;Jae-Won Kim","doi":"10.1109/TNB.2023.3284406","DOIUrl":"10.1109/TNB.2023.3284406","url":null,"abstract":"Ever since deoxyribonucleic acid (DNA) was considered as a next-generation data-storage medium, lots of research efforts have been made to correct errors occurred during the synthesis, storage, and sequencing processes using error correcting codes (ECCs). Previous works on recovering the data from the sequenced DNA pool with errors have utilized hard decoding algorithms based on a majority decision rule. To improve the correction capability of ECCs and robustness of the DNA storage system, we propose a new iterative soft decoding algorithm, where soft information is obtained from FASTQ files and channel statistics. In particular, we propose a new formula for log-likelihood ratio (LLR) calculation using quality scores (Q-scores) and a redecoding method which may be suitable for the error correction and detection in the DNA sequencing area. Based on the widely adopted encoding scheme of the fountain code structure proposed by Erlich et al., we use three different sets of sequenced data to show consistency for the performance evaluation. The proposed soft decoding algorithm gives 2.3%\u0000<inline-formula> <tex-math>$sim $ </tex-math></inline-formula>\u00007.0% improvement of the reading number reduction compared to the state-of-the-art decoding method and it is shown that it can deal with erroneous sequenced oligo reads with insertion and deletion errors.","PeriodicalId":13264,"journal":{"name":"IEEE Transactions on NanoBioscience","volume":"23 1","pages":"81-90"},"PeriodicalIF":3.9,"publicationDate":"2023-06-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"9601921","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"生物学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0