Homeopathy最新文献

{"title":"Homeopathic Medicines in the Management of Dermatophytosis (Tinea Infections): A Clinico-epidemiological Study with Pre-post Comparison Design.","authors":"Ashish Kumar Dixit, Danish Javed, Amit Srivastava, Renu Bala, Nibha Giri","doi":"10.1055/s-0043-1771023","DOIUrl":"10.1055/s-0043-1771023","url":null,"abstract":"<p><strong>Background: </strong>Dermatophytosis is a common fungal infection of the skin and nails. Insufficient data exist regarding the clinico-epidemiological profile of dermatophytosis and the usefulness of individualized homeopathic medicines (IHMs) for patients visiting a homeopathy outpatient department (OPD).</p><p><strong>Objectives: </strong>This article undertakes a clinico-epidemiological profiling of dermatophytosis and the usefulness of IHMs in its management.</p><p><strong>Methods: </strong>This open-label, pre-post, comparative observational study was conducted in a homeopathy OPD from November 2018 to February 2020. IHMs were prescribed based on symptom totality and repertorization. A numeric rating scale (NRS) and the Dermatology Life Quality Index (DLQI) patient questionnaires were used, and results were analyzed using SPSS-IBM version 20.</p><p><strong>Results: </strong>Data from a total of 103 patients, mean age 29.65 ± 15.40 years, were analyzed. <i>Tinea cruris</i> was the most common infection (29.1%), followed by <i>tinea corporis</i> (13.6%). After 3 months of treatment, significant reductions in NRS and DLQI scores were observed (8.51 ± 1.24 to 0.59 ± 0.83, <i>p</i> < 0.001, and 16.28 ± 5.30 to 1.44 ± 1.56, <i>p</i> < 0.001, respectively), with <i>Sepia</i> (15.5%), <i>Sulphur</i> (14.6%), <i>Calcarea carbonica</i> (11.7%), <i>Natrum muriaticum</i> (9.7%) and <i>Bacillinum</i> (8.7%) being the most frequently prescribed medicines. There was no significant correlation between occupation, sex, home location or marital status and the clinical types of dermatophytosis. No adverse events were reported.</p><p><strong>Conclusion: </strong><i>T. cruris</i> and <i>T. corporis</i> were prevalent dermatophytic infections. The decrease in NRS and DLQI scores associated with homeopathy indicates its usefulness as an integrative treatment option for dermatophytosis. Further research in larger and more diverse population samples is needed.</p>","PeriodicalId":13227,"journal":{"name":"Homeopathy","volume":" ","pages":"149-157"},"PeriodicalIF":1.2,"publicationDate":"2024-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"71423329","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Principles in Practice.","authors":"Robert T Mathie","doi":"10.1055/s-0044-1787816","DOIUrl":"10.1055/s-0044-1787816","url":null,"abstract":"","PeriodicalId":13227,"journal":{"name":"Homeopathy","volume":"113 3","pages":"131"},"PeriodicalIF":1.2,"publicationDate":"2024-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141765937","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Individualized Homeopathic Medicines in the Treatment of Knee Osteoarthritis: Double-Blind, Randomized, Placebo-Controlled Feasibility Trial.","authors":"Soumya Bhattacharyya, Chandrima Chatterjee, Subhranil Saha, Satyajit Naskar, Pulakendu Bhattacharya, Sk Monsur Alam, Sumana Sengupta, Sabir Ahamed, Abdur R Shaikh, Munmun Koley, Priyanka Ghosh, Shyamal K Mukherjee","doi":"10.1055/s-0043-1771025","DOIUrl":"10.1055/s-0043-1771025","url":null,"abstract":"<p><strong>Introduction: </strong>This study aimed at examining the feasibility issues of comparing individualized homeopathic medicines (IHMs) with identical-looking placebos for treating knee osteoarthritis (OA).</p><p><strong>Methods: </strong>Forty eligible patients participated in this double-blind, randomized (1:1), placebo-controlled feasibility trial in the outpatient clinics of a homeopathic hospital in West Bengal, India. Either IHMs or identical-looking placebos were administered, along with mutually agreed-upon concomitant care guidelines. The Knee Injury and Osteoarthritis Outcome Score (KOOS) was the primary outcome measure, along with derived Western Ontario and McMaster Universities Arthritis Index (WOMAC) scores from KOOS. The EQ-5D-5L questionnaire and Visual Analog Scale (VAS) were the secondary outcomes. All were measured at baseline and after 2 months. Group differences and effect sizes (Cohen's <i>d</i>) were estimated using an intention-to-treat approach. <i>p</i>-Values less than 0.05 (two-tailed) were considered statistically significant.</p><p><strong>Results: </strong>Enrolment/screening and trial retention rates were 43% and 85% respectively. Recruitment was difficult owing to the coronavirus disease 2019 (COVID-19) lockdown. Group differences were statistically significant, favoring IHMs against placebos in all the KOOS sub-scales: symptoms (<i>p</i> < 0.001), pain (<i>p</i> = 0.002), activities of daily living (<i>p</i> < 0.001), sports or recreation (<i>p</i> = 0.016), and quality of life (<i>p</i> = 0.002). Derived WOMAC scores from KOOS favored IHMs against placebos: stiffness (<i>p</i> < 0.001) and pain (<i>p</i> < 0.001). The EQ-5D-5L questionnaire score (<i>p</i> < 0.001) and EQ-5D-5L VAS scores (<i>p</i> < 0.001) also yielded significant results, favoring IHMs over placebos. All the effect sizes ranged from moderate to large. <i>Sulphur</i> was the most frequently prescribed homeopathic medication. Neither group reported any harm or serious adverse events.</p><p><strong>Conclusion: </strong>Although recruitment was sub-optimal due to prevailing COVID-19 conditions during the trial, the action of IHMs was found to be superior to that of placebos in the treatment of knee OA. Larger and more definitive studies, with independent replications, are warranted in order to substantiate the findings.</p><p><strong>Trial registration: </strong>CTRI/2021/02/031453.</p>","PeriodicalId":13227,"journal":{"name":"Homeopathy","volume":" ","pages":"158-166"},"PeriodicalIF":1.2,"publicationDate":"2024-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"41121010","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Prevalence of COVID-19 Complications during a Program of Homeopathic Camphora Officinalis Distribution to City Populations of Santa Catarina, Brazil: An Ecological Study.","authors":"Edgard Costa de Vilhena, Nicolle R Telles Coutracos, Ednar N Coimbra, Karen Berenice Denez, Adriana Passos Oliveira, Carla Holandino, Vânia Emerich Bucco de Campos, Giovanni Bravin Peres, Leoni Villano Bonamin","doi":"10.1055/s-0044-1786511","DOIUrl":"https://doi.org/10.1055/s-0044-1786511","url":null,"abstract":"<p><strong>Background: </strong> Coronavirus disease 2019 (COVID-19), a disease caused by the SARS-CoV-2 coronavirus, was declared a pandemic in March 2020, posing significant challenges globally. Homeopathy has historical relevance in epidemic management. In response, the government of the state of Santa Catarina, Brazil, distributed <i>Camphora</i> 1M as a potential prophylactic intervention for COVID-19.</p><p><strong>Objective: </strong> This study aimed to investigate the possible effects of <i>Camphora</i> 1M as an adjunctive prophylactic measure in managing COVID-19, focusing on mortality and hospitalization rates, during the period April 28 to July 31, 2020, within designated COVID-19 in-patient units in Santa Catarina.</p><p><strong>Methods: </strong> An ecological study design was applied to this epidemiological research. Five case municipalities (Itajaí, Atalanta, Entre Rios, Rio do Campo, Trombudo Central) were compared with five control municipalities (São José, Galvão, Pedras Grandes, Grão-Pará, Ascurra).</p><p><strong>Results: </strong> No statistically significant differences were observed in predictor variables between municipalities that received <i>Camphora</i> 1M and the respective controls. Similarly, no statistically significant differences were observed in outcomes: deaths (<i>p</i> = 0.879), hospitalized cases (<i>p</i> = 0.537), daily ward admissions (<i>p</i> = 0.730) and ICU admissions (<i>p</i> = 0.072).</p><p><strong>Conclusion: </strong> For the first wave of the pandemic in the state of Santa Catarina, Brazil, city-wide distribution of <i>Camphora</i> 1M was not associated with reduced numbers, severity or mortality among the population hospitalized in designated public hospitals for COVID-19.</p>","PeriodicalId":13227,"journal":{"name":"Homeopathy","volume":" ","pages":""},"PeriodicalIF":1.2,"publicationDate":"2024-07-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141579529","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Estimation of the Likelihood Ratio of Different Symptoms for Six Homeopathic Medicines: Prognostic Factor Research.","authors":"Aditi Mohanta, Nipa Sardar, Koli Chakraborty, Malabika Sarkar, Tamoghna Saha, Anuruddha Deb, Md Sakhawat Hossain, Arpita Basu, Saima Samim, Soumya Bhattacharyya, Sangita Saha, Biswajit Basu, Anindya Sen, Mohan Giri, Pintu Debnath, Subhranil Saha, Munmun Koley, Shyamal Kumar Mukherjee, Lex Rutten","doi":"10.1055/s-0044-1787078","DOIUrl":"https://doi.org/10.1055/s-0044-1787078","url":null,"abstract":"<p><strong>Background: </strong> <i>Arsenicum album</i>, <i>Causticum</i>, <i>Nux vomica</i>, <i>Pulsatilla nigricans</i>, <i>Rhus toxicodendron</i> and <i>Sulphur</i> are frequently prescribed homeopathic medicines; however, their symptoms, as mentioned in different homeopathic literature works, have rarely been investigated systematically. Likelihood ratio (LR), based on Bayesian statistics, may reflect a better estimation of the strengths of symptoms than the existing entries in the homeopathic literature.</p><p><strong>Methods: </strong> A prospective, longitudinal, analytical patient outcome study was conducted in the outpatient departments of D. N. De Homeopathic Medical College and Hospital, Kolkata, on 1,954 patients over 21 months. The outcomes were recorded at each follow-up using the Outcome Related to Impact on Daily Living (ORIDL) +4 to -4 scale. The average period of treatment for each participant was 3 months. The LRs of four symptoms for each of the six selected medicines were calculated.</p><p><strong>Results: </strong> One hundred and two different remedies were prescribed. The prevalence, LR + , and LR - , with respective 95% confidence intervals, of different symptoms were reported. The study found that the following symptoms had particularly high LR+ scores: \"intense sympathy for the suffering of others\" (<i>Causticum</i>, LR+ = 12.0); \"dyspepsia from business anxiety\" (<i>Nux vomica</i>, LR+ = 27.4); \"burning pain relieved by heat\" (<i>Arsenicum album</i>, LR+ = 29.6); \"envy\" (<i>Pulsatilla nigricans</i>, LR+ = 13.2); \"desire for milk\" (<i>Rhus toxicodendron</i>, LR+ = 7.5); \"very selfish, no regard for others\" (<i>Sulphur</i>, LR+ = 20.6). The findings corroborated well with the presentation of the symptoms in different homeopathic materia medica and repertories. ORIDL scores of +2 or greater were identified most prominently for <i>Pulsatilla nigricans</i> (<i>n</i> = 138) and <i>Sulphur</i> (<i>n</i> = 119).</p><p><strong>Conclusion: </strong> There was adequate evidence to attribute all the assessed symptoms to the medicines investigated. Further studies with a larger population are warranted to tackle the possible confirmation bias.</p>","PeriodicalId":13227,"journal":{"name":"Homeopathy","volume":" ","pages":""},"PeriodicalIF":1.2,"publicationDate":"2024-07-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141558611","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Historical Perspective of Homeopathy in the Brazilian Public Health System.","authors":"Fernanda Maria Simões da Costa Fujino, Jane de Eston Armond, Ana Paula Ribeiro, Patrícia Colombo de Souza","doi":"10.1055/s-0044-1786739","DOIUrl":"https://doi.org/10.1055/s-0044-1786739","url":null,"abstract":"<p><p>Homeopathy was introduced in Brazil with the French doctor Benoît Jules Mure's arrival in 1840 and was officially recognised in 1980 as a medical specialty by Brazilian regulatory authorities. Public health policies played an important role in incorporating homeopathy into the Brazilian Unified Health System (SUS), emphasising homeopathy's coherence with SUS's fundamental principles and with other national health policies. Homeopathy is supported by the guidelines of the National Primary Health Care Policy and the National Policy on Integrative and Complementary Practices, and its offer in the SUS has been recognised since 2006. Challenges persist, however, such as the low prevalence of the use of homeopathy, lack of investment in professional training and under-reporting of homeopathy outpatient appointments. Investments in disseminating information on homeopathic philosophy and raising awareness among managers and health professionals are essential to strengthen its presence in the Brazilian public health system.</p>","PeriodicalId":13227,"journal":{"name":"Homeopathy","volume":" ","pages":""},"PeriodicalIF":1.2,"publicationDate":"2024-07-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141558612","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Multidimensional Outcome Parameters in a Cress Seedling-CuCl2 Crystallization Assay to Corroborate Specific Effects of Stannum metallicum 30x Compared to Lactose 30x.","authors":"Paul Doesburg, Jens-Otto Andersen, Claudia Scherr, Maria Olga Kokornaczyk, Stephan Baumgartner","doi":"10.1055/s-0044-1785517","DOIUrl":"https://doi.org/10.1055/s-0044-1785517","url":null,"abstract":"<p><strong>Background: </strong> Previously we developed a test system which yielded highly significant evidence for specific effects of a <i>Stannum metallicum</i> 30x preparation in a multi-center replication trial. This test system is based on cress seed germination in homeopathic or control samples, CuCl₂ crystallization of the cress extract, and subsequent digital textural image analysis of the resulting crystallization patterns.</p><p><strong>Objectives: </strong> The current study aimed to investigate whether three novel outcome parameters could further corroborate and possibly characterize the specific effects of <i>Stannum metallicum</i> 30x.</p><p><strong>Methods: </strong> To this end, (1) cress seedling length, (2) a second texture analysis parameter, entropy and (3) the local connected fractal dimension (LCFD) of crystallization patterns as a measure of complexity were considered. The stability of the experimental setup was monitored throughout the entire investigation with systematic negative control (SNC) experiments.</p><p><strong>Results: </strong> Cress length and entropy revealed a time-modulated potency treatment effect, in the absence of a significant main treatment effect. This indicated that the effect of the potency treatment varied significantly across the different experimental days. LCFD yielded a highly significant potency treatment effect. In addition, a significant interaction of treatment with experimental day seems to indicate a modulation of this effect. No significant effects were observed in any of the evaluations of the SNC experiments, indicative of a stable experimental setup and a reliable and specific treatment effect. Neither significant nor strong correlations were found between the four parameters, indicating that they reflect different effects of <i>Stannum metallicum</i> 30x on the organism treated.</p><p><strong>Conclusion: </strong> This quadruple characterization of the biological effects of <i>Stannum metallicum</i> 30x provides an unprecedented opportunity for basic homeopathy research into, among others, the presumed specificity of homeopathic preparations.</p>","PeriodicalId":13227,"journal":{"name":"Homeopathy","volume":" ","pages":""},"PeriodicalIF":1.7,"publicationDate":"2024-06-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141310615","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"The Patient Population at Homeopathic Outpatient Clinics across India: A Clinical Data Collection Study.","authors":"Harleen Kaur, Surbhi Jain, Daisy Katarmal, Jyoti Sachdeva, Hima Bindu Ponnam, K C Muraleedharan, Suraia Parveen, Sonia Raizada, Liyi Karso, Renu Bala, Amit Srivastava, Vaishali Shinde, Sunil Ramteke, Gurudev Choubey, Chittaranjan Kundu, Vinitha E Ramanan, Tejaswini Patole, Ranjit Sonny, Baidurjya Bhattacharjee, Ravi Kumar Sardarla, Ramesh S Bawaskar, G R C Reddy, Kumar Keshav Avinash, Santosh Tamang, Akhyaya Kumar Prusty, Madhumita Sadhukhan, Artemis Maglara, Anastasia Garoufali, Michael Stassinopoulos, Theodoros Lilas, Lefteris Tapakis, Anil Khurana, Raj K Manchanda","doi":"10.1055/s-0044-1782221","DOIUrl":"https://doi.org/10.1055/s-0044-1782221","url":null,"abstract":"<p><strong>Background: </strong> Even though several initiatives have been undertaken in different locations worldwide to collect clinical data in homeopathy, it is important to further investigate these aspects in the context of health care in India.</p><p><strong>Objective: </strong> The study aimed to gather and analyze patients' clinical data and to derive insights into homeopathic treatment using an internet-based software program for data storage, retrieval and repertorization.</p><p><strong>Methods: </strong> A multi-center observational study was conducted across 14 homeopathy outpatient clinics in India that are affiliated with the Central Council for Research in Homoeopathy (CCRH). Patient symptoms and demographic details were documented anonymously, and prescriptions were guided by repertorial suggestions from the Vithoulkas Compass software. During follow-up visits, treatment outcome was also recorded using an online assessment form. A retrospective analysis of data on patients' demographics, follow-up visits, morbidity (International Classification of Diseases 11th Revision), rubrics used, prescribed medicines and the level of improvement was achieved using Microsoft Excel-generated pivot tables.</p><p><strong>Results: </strong> Throughout the study duration of one year a total of 2,811 patients attended the 14 outpatient clinics, of whom 2,468 were new patients with a total of 2,172 initial homeopathic prescription entries. Across the study, there were 3,491 prescriptions and 1,628 follow-up consultations for 868 follow-up patients, all of which data were thoroughly analyzed. The highest frequency of patients was in the 20-49 age group, and a higher proportion of the patients overall was female. Musculoskeletal, dermatological and respiratory complaints were the most frequently reported. The rubrics \"Desire for sweets\" and \"Desire for spices\" emerged as the most commonly used in the repertorizations. Further, <i>Sulphur</i> stood out as the most commonly prescribed medicine overall. With homeopathic treatment, some degree of clinical improvement was reported in 86% of the follow-up cases.</p><p><strong>Conclusion: </strong> Homeopathy is prescribed in CCRH outpatient clinics for a wide range of ailments in people across India, with at least some clinical improvement noted in a high proportion of those patients. The large-scale systematic data collection in these clinics has provided clear insights into the use and clinical value of homeopathy in India, with the potential to build a substantive nationwide data inventory over time.</p>","PeriodicalId":13227,"journal":{"name":"Homeopathy","volume":" ","pages":""},"PeriodicalIF":1.7,"publicationDate":"2024-05-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141183409","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Homeopathy as a Means to Improve Quality of Life.","authors":"Fernanda Maria Simões da Costa Fujino, Ana Paula Ribeiro, Jane de Eston Armond, Patrícia Colombo de Souza","doi":"10.1055/s-0044-1785521","DOIUrl":"https://doi.org/10.1055/s-0044-1785521","url":null,"abstract":"<p><p>Quality of life is a fundamental aspect of good health and differs from person to person, highlighting the importance of individualisation, which is one of the principles of homeopathic doctrine. Homeopathy aligns with the principles of the Brazilian public health system, reflecting the latter's ethos of universality, accessibility, care coordination, and comprehensiveness, offering a whole-person approach to health care. Homeopathy's individualised approach and expanded view of the health-disease process, with emphasis on healthy lifestyle guidance, contributes to the promotion of individual good health and quality of life. These attributes of homeopathy make it a valuable therapeutic option, with relevance to the health service of Brazil as well as to that of other countries across the world.</p>","PeriodicalId":13227,"journal":{"name":"Homeopathy","volume":" ","pages":""},"PeriodicalIF":1.7,"publicationDate":"2024-05-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141160338","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Protocol Standardization of Homeopathic Medicines' Preparation and Dosing for Experimental Model Systems In Vitro.","authors":"Nilanjana Basu, Simran Tandon","doi":"10.1055/s-0044-1786513","DOIUrl":"https://doi.org/10.1055/s-0044-1786513","url":null,"abstract":"","PeriodicalId":13227,"journal":{"name":"Homeopathy","volume":" ","pages":""},"PeriodicalIF":1.7,"publicationDate":"2024-05-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140916435","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}