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Homeopathic Management of Bulky Uterus with Uterine Fibroid in a 40-year-old Patient: An Evidence-Based Case Report.
IF 1.2 4区 医学
Homeopathy Pub Date : 2024-12-30 DOI: 10.1055/s-0044-1790513
Bharti Wadhwa, Shweta Singh Kureel
{"title":"Homeopathic Management of Bulky Uterus with Uterine Fibroid in a 40-year-old Patient: An Evidence-Based Case Report.","authors":"Bharti Wadhwa, Shweta Singh Kureel","doi":"10.1055/s-0044-1790513","DOIUrl":"https://doi.org/10.1055/s-0044-1790513","url":null,"abstract":"<p><strong>Background: </strong> Uterine fibroids are benign gynecological tumours that arise in the uterine smooth muscle tissue and are characterized by the production of excessive quantities of extracellular matrix. Various therapeutic options, from medical management to surgical intervention, exist for uterine fibroids, for which homeopathy has emerged as a promising therapeutic option in patient-centered care.</p><p><strong>Case history: </strong> A 40-year-old woman presented with complaints of heavy menstrual bleeding, with pain in the pelvic region and back. She was diagnosed as a case of bulky uterus with uterine fibroid. The patient opted for homeopathic management and was prescribed <i>Thuja occidentalis</i> based on individualization, miasmatic analysis and repertorial totality.</p><p><strong>Results: </strong> After treatment, there was regression in size of the fibroid within 5 months, with complete resolution and restoration of the uterus to normal size within 9 months. Changes were validated through ultrasonography, which added objective evidence to the positive outcome. The Modified Naranjo Criteria for Homeopathy (MONARCH) inventory total score was +9, which indicated causal attribution of clinical outcome to the homeopathic intervention.</p><p><strong>Conclusion: </strong> This case study has illustrated the clinical benefits of homeopathy in the management of a patient with uterine fibroids, reaffirming the need for further research to explore its value as a therapeutic option for individuals seeking alternative or complementary approaches for appropriate medical conditions.</p>","PeriodicalId":13227,"journal":{"name":"Homeopathy","volume":" ","pages":""},"PeriodicalIF":1.2,"publicationDate":"2024-12-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142921546","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Presentation and Analysis of the Online Evidence Gap Map, "Clinical Effectiveness of Homeopathy".
IF 1.2 4区 医学
Homeopathy Pub Date : 2024-12-24 DOI: 10.1055/s-0044-1791490
Leoni V Bonamin, Ubiratan C Adler, Edgard C de Vilhena, Carla Holandino Quaresma, Adriana Passos de Oliveira, Ednar N Coimbra, Jorge K Hosomi, Carmen Veronica M Abdala, Mariana C Schveitzer, Caio F S Portella, Ricardo Ghelman
{"title":"Presentation and Analysis of the Online Evidence Gap Map, \"Clinical Effectiveness of Homeopathy\".","authors":"Leoni V Bonamin, Ubiratan C Adler, Edgard C de Vilhena, Carla Holandino Quaresma, Adriana Passos de Oliveira, Ednar N Coimbra, Jorge K Hosomi, Carmen Veronica M Abdala, Mariana C Schveitzer, Caio F S Portella, Ricardo Ghelman","doi":"10.1055/s-0044-1791490","DOIUrl":"https://doi.org/10.1055/s-0044-1791490","url":null,"abstract":"&lt;p&gt;&lt;strong&gt;Introduction and objective: &lt;/strong&gt; This study presents and analyzes the content of an online Evidence Gap Map (EGM), \"&lt;i&gt;Clinical Effectiveness of Homeopathy, 1st Edition&lt;/i&gt;\", which graphically represents evidence from systematic reviews (SRs) of human clinical trials in homeopathy that were published from 1991 to 2021. The EGM was built according to the guidelines of the International Initiative for Impact Evaluation (3ie), adapted for complex interventions, to represent visually relevant evidence and research gaps.&lt;/p&gt;&lt;p&gt;&lt;strong&gt;Presentation of evidence gap map content: &lt;/strong&gt; The interventions, classified as rows, are characterized in the EGM not only by the homeopathic therapeutic strategy but also by individual medicines and potencies. The outcomes are listed in columns. The associations between both are represented by \"bubbles\" that refer to the corresponding SRs and whose colors indicate their quality level.&lt;/p&gt;&lt;p&gt;&lt;strong&gt;Synthesis of evidence gap map content: &lt;/strong&gt; From 239 citations identified, 51 SRs underwent complete characterization for the final construction of the EGM. A further in-depth quality analysis of each SR was performed to list the studied intervention/outcome associations described in each mentioned trial. At this step, those trials considered to have a high risk of bias by the authors of each SR were excluded from the EGM inputs.&lt;/p&gt;&lt;p&gt;&lt;strong&gt;Analysis of evidence gap map content: &lt;/strong&gt; The methodological quality of each of the EGM's SRs was evaluated using the AMSTAR-2 criteria for level of confidence in an SR's results. Intervention-outcome associations were categorized into one of five effects of a homeopathic intervention: &lt;i&gt;positive&lt;/i&gt;, &lt;i&gt;potentially positive&lt;/i&gt;, &lt;i&gt;ineffective&lt;/i&gt;, &lt;i&gt;inconclusive&lt;/i&gt;, or &lt;i&gt;negative&lt;/i&gt;.&lt;/p&gt;&lt;p&gt;&lt;strong&gt;Findings: &lt;/strong&gt; The EGM presents research evidence across a wide range of medical conditions, with substantial heterogeneity of homeopathic interventions and clinical outcomes. Forty-two of the 51 SRs yielded inconclusive findings. AMSTAR-2 analysis identified seven high-quality SRs, in which reliable primary studies presenting positive or potentially positive results for different categories of homeopathy are cited and related to specific clinical conditions: fibromyalgia, otitis media, diarrhea, respiratory infections, menopausal syndrome, irritable bowel syndrome, and attention deficit hyperactivity disorder in children.&lt;/p&gt;&lt;p&gt;&lt;strong&gt;Conclusion: &lt;/strong&gt; The EGM \"&lt;i&gt;Clinical Effectiveness of Homeopathy, 1st Edition&lt;/i&gt;\" presents visually relevant research evidence that is scattered across a large number of medical conditions, showing substantial heterogeneity of homeopathic interventions, clinical outcomes, and research quality. To enhance the precision and relevance of future research, we recommend that the individualized homeopathic approach under investigation be standardized to the greatest extent feasible, and to use measures of well-being ","PeriodicalId":13227,"journal":{"name":"Homeopathy","volume":" ","pages":""},"PeriodicalIF":1.2,"publicationDate":"2024-12-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142885819","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
China officinalis as Possible Homeopathic Prophylaxis for the Brazilian Dengue Epidemic.
IF 1.2 4区 医学
Homeopathy Pub Date : 2024-12-19 DOI: 10.1055/s-0044-1792147
Ana Amélia Campos Claro Olandim, Fernanda Maria Simões da Costa Fujino, Renata Lemonica, Nilson Roberti Benites, Vagner Doja Barnabé
{"title":"China officinalis as Possible Homeopathic Prophylaxis for the Brazilian Dengue Epidemic.","authors":"Ana Amélia Campos Claro Olandim, Fernanda Maria Simões da Costa Fujino, Renata Lemonica, Nilson Roberti Benites, Vagner Doja Barnabé","doi":"10.1055/s-0044-1792147","DOIUrl":"https://doi.org/10.1055/s-0044-1792147","url":null,"abstract":"<p><p>Dengue, a hyperendemic arbovirus thriving in tropical and sub-tropical climates globally, has seen a significant surge in Brazil over the past 5 years. Presently, the country faces an epidemic, posing a huge challenge to Public Health authorities due to the potentially lethal nature of severe infections. Based on Hahnemannian concepts and on the historically reported efficacy of homeopathy in fighting epidemics, this study aimed to provide supporting evidence for a homeopathic genus epidemicus approach to prevent severe forms of dengue. Symptoms related to the severe phase of the disease were prioritised in the repertorisation: <i>China officinalis</i> (<i>Chin</i>) received the highest total symptoms score (43 points from 21 symptoms) followed by <i>Arsenicum album</i> (31/13) and <i>Phosphorus</i> (29/14). In the asymptomatic population exposed to the etiological agent, the use of <i>Chin</i> might contribute as an additional strategy in the prophylaxis of dengue.</p>","PeriodicalId":13227,"journal":{"name":"Homeopathy","volume":" ","pages":""},"PeriodicalIF":1.2,"publicationDate":"2024-12-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142864121","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
MONARCH Inventory for Causal Attribution in Homeopathy Case Reports: Explanation and Elaboration.
IF 1.2 4区 医学
Homeopathy Pub Date : 2024-12-19 DOI: 10.1055/s-0044-1792166
Chetna Deep Lamba, Nidhi Mahajan, Vishwa Kumar Gupta, Lex Rutten, Michael Teut, Lefteris Tapakis, Todd Hoover, Anna Gerstenhoefer, Yuen Ying Yvonne Fok, Rajkumar Manchanda, Robbert van Haselen
{"title":"MONARCH Inventory for Causal Attribution in Homeopathy Case Reports: Explanation and Elaboration.","authors":"Chetna Deep Lamba, Nidhi Mahajan, Vishwa Kumar Gupta, Lex Rutten, Michael Teut, Lefteris Tapakis, Todd Hoover, Anna Gerstenhoefer, Yuen Ying Yvonne Fok, Rajkumar Manchanda, Robbert van Haselen","doi":"10.1055/s-0044-1792166","DOIUrl":"https://doi.org/10.1055/s-0044-1792166","url":null,"abstract":"<p><strong>Background: </strong> The Modified Naranjo Criteria for Homeopathy (MONARCH) inventory is a novel and useful tool for assessing the likelihood of a causal relationship between the homeopathic intervention and the ultimate clinical outcome.</p><p><strong>Objectives: </strong> To explain and elaborate on the use of the MONARCH inventory to improve its consistency of use and thereby elevate the overall quality and evidentiary value of homeopathy case reports.</p><p><strong>Explanation and elaboration: </strong> Each of the 10 MONARCH inventory domains is explained and elaborated with the aid of references from published literature and hypothetical clinical situations. The MONARCH total score can range from -6 to +13; within that range, an arithmetic total of +6 is available from the scores of four critical domains, which should be given prominence in the overall consideration of causality. In reporting a clinical case, great importance should be placed on the narrative of the MONARCH evaluation process, domain by domain.</p><p><strong>Conclusion: </strong> The application of MONARCH allows us to evaluate the likelihood of a causal relationship between the intervention and the observed clinical outcomes in successfully treated cases, thereby augmenting their evidentiary value.</p>","PeriodicalId":13227,"journal":{"name":"Homeopathy","volume":" ","pages":""},"PeriodicalIF":1.2,"publicationDate":"2024-12-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142864124","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Tracking a Homeopathic Complex Formulation in the Watercourses of a Fire-Damaged State Park in Brazil. 在巴西受火灾破坏的州立公园水道中追踪顺势疗法复方制剂。
IF 1.2 4区 医学
Homeopathy Pub Date : 2024-11-11 DOI: 10.1055/s-0044-1790284
Nathalia Salles Scortegagna de Medeiros, Andréia Adelaide G Pinto, Sérgio Frana, Mônica Filomena Souza, Ana Paula Felício, Ivana Barbosa Suffredini, Steven John Cartwright, Leoni Villano Bonamin
{"title":"Tracking a Homeopathic Complex Formulation in the Watercourses of a Fire-Damaged State Park in Brazil.","authors":"Nathalia Salles Scortegagna de Medeiros, Andréia Adelaide G Pinto, Sérgio Frana, Mônica Filomena Souza, Ana Paula Felício, Ivana Barbosa Suffredini, Steven John Cartwright, Leoni Villano Bonamin","doi":"10.1055/s-0044-1790284","DOIUrl":"https://doi.org/10.1055/s-0044-1790284","url":null,"abstract":"<p><strong>Introduction: </strong> In 2020, a 26,849-ha state park in Mato Grosso do Sul state, Brazil, had 30% of its area damaged by fire. A homeopathic complex formulation was applied at strategic point locations in the park's springs or watercourses, aiming to mitigate the fire damage to the flora and fauna as quickly as possible. The duration of the homeopathic signal at each point was assessed using an established solvatochromic dye technique.</p><p><strong>Objective: </strong> To evaluate the timing and the nature of the signal at each of nine point locations. We could thus identify the presence of any signal variations due to specified environmental features within the park.</p><p><strong>Methods: </strong> Water samples were harvested from each intervention point at different times, filtered, frozen, and sent to the laboratory, where they were prepared to 1cH using filtered 30% ethanol. Methylene violet was chosen among six dyes since it was found in preliminary tests that it could trace the homeopathic complex used. In addition to simple sample testing, samples were submitted to a static and unidirectional magnetic field of 2400 Gauss (240 mT) for 15 minutes immediately before reading, which enhanced the method's sensitivity. One-way analysis of variance/Tukey test was used to identify dye absorbance changes following the analysis of water samples from the watercourse system. A correlation matrix and the Spearman <i>r</i> test were employed to evaluate any correlation between tracking and the pre-existing anthropic interventions at harvesting points. In all cases, α = 0.05.</p><p><strong>Results: </strong> Four tracking patterns using the sample magnetization process were observed in relation to water samples and their effect on methylene violet solutions: no response (P2, P4), early transitory response (P5, P6, P8), late response (P1, P9), and constant response (P3, P7). P2 and P4, which could not be tracked, were correlated with permanent local anthropic disturbance.</p><p><strong>Conclusions: </strong> Methylene violet was the best dye to track the homeopathic complex prepared specifically for this case. Tracking was facilitated by prior magnetic treatment of samples, but anthropic disturbances to the environment seem to interfere with it.</p>","PeriodicalId":13227,"journal":{"name":"Homeopathy","volume":" ","pages":""},"PeriodicalIF":1.2,"publicationDate":"2024-11-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142619351","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Association between Acute and Chronic Inflammatory States: A Case-Control Study. 急性和慢性炎症状态之间的关联:病例对照研究
IF 1.2 4区 医学
Homeopathy Pub Date : 2024-11-01 Epub Date: 2024-02-09 DOI: 10.1055/s-0043-1777119
Seema Mahesh, Mahesh Mallappa, Vitalie Vacaras, Viraj Shah, Elena Serzhantova, Nadezhda Kubasheva, Dmitriy Chabanov, Dionysios Tsintzas, Latika Jaggi, Atul Jaggi, George Vithoulkas
{"title":"Association between Acute and Chronic Inflammatory States: A Case-Control Study.","authors":"Seema Mahesh, Mahesh Mallappa, Vitalie Vacaras, Viraj Shah, Elena Serzhantova, Nadezhda Kubasheva, Dmitriy Chabanov, Dionysios Tsintzas, Latika Jaggi, Atul Jaggi, George Vithoulkas","doi":"10.1055/s-0043-1777119","DOIUrl":"10.1055/s-0043-1777119","url":null,"abstract":"<p><strong>Background: </strong>Fever is the hallmark of efficient acute inflammatory response, which may be disrupted in chronic inflammatory conditions. The \"continuum theory\" proposes that the return of acute inflammatory states with high fever predicts improvement in chronic diseases during treatment. Our objective was to investigate the observation made, during classical homeopathic treatment, that such an association exists between chronic inflammation and efficient acute inflammation.</p><p><strong>Methods: </strong>In a case-control study, the reports of patients diagnosed with chronic inflammatory conditions with at least 6 months of follow-up under homeopathic treatment were retrospectively sampled from homeopathic medical practices from Greece, India, Romania and Russia. Twenty patients who improved under homeopathic treatment and 20 age-matched controls of those who did not improve were selected. The occurrence of common acute infectious diseases with fever during the follow-up period was investigated.</p><p><strong>Results: </strong>The average age of the cases and controls was 28.4 (SD: 16.64) and 27.9 (SD: 17.19) years respectively. 18/20 cases and 4/20 controls developed common infectious diseases with fever. Cramer's V co-efficient value was found to be 0.551 (<i>p</i> < 0.01), indicating that improvement was more in patients with fever than without. Odds ratio of improving with respect to development of acute infectious diseases was 36.0 (95% CI: 5.8 to 223.5). The binary logistic regression model indicated significant contribution of occurrence of acute infections with fever as a predictor for improvement in chronic inflammatory disease.</p><p><strong>Conclusions: </strong>Classical homeopathic clinical observations indicate an association between chronic inflammatory status in the body and the ability to mount efficient acute inflammation. In this case-control study, the occurrence of common infections with fever during treatment heralded improvement in chronic inflammatory disease. Further powered studies are necessary to substantiate this finding.</p>","PeriodicalId":13227,"journal":{"name":"Homeopathy","volume":" ","pages":"239-244"},"PeriodicalIF":1.2,"publicationDate":"2024-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11493469/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139711985","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Homeopathy's Enhanced Scope and Recognition. 顺势疗法的扩大范围和认可度。
IF 1.2 4区 医学
Homeopathy Pub Date : 2024-11-01 Epub Date: 2024-10-21 DOI: 10.1055/s-0044-1791285
Robert T Mathie
{"title":"Homeopathy's Enhanced Scope and Recognition.","authors":"Robert T Mathie","doi":"10.1055/s-0044-1791285","DOIUrl":"https://doi.org/10.1055/s-0044-1791285","url":null,"abstract":"","PeriodicalId":13227,"journal":{"name":"Homeopathy","volume":"113 4","pages":"209-210"},"PeriodicalIF":1.2,"publicationDate":"2024-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142464198","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Individualized Homeopathic and Organopathic Supportive Management of Sickle Cell Disorder: A Case Series of Six Patients from a Particularly Vulnerable Tribal Group in India. 镰状细胞病的个性化顺势疗法和有机疗法辅助治疗:来自印度一个特别弱势部落群体的六名患者的病例系列。
IF 1.2 4区 医学
Homeopathy Pub Date : 2024-11-01 Epub Date: 2024-01-30 DOI: 10.1055/s-0043-1776908
Nisanth K M Nambison, Narendra Sharma, Abhishek D Dwivedi, Nisha Chakravarty
{"title":"Individualized Homeopathic and Organopathic Supportive Management of Sickle Cell Disorder: A Case Series of Six Patients from a Particularly Vulnerable Tribal Group in India.","authors":"Nisanth K M Nambison, Narendra Sharma, Abhishek D Dwivedi, Nisha Chakravarty","doi":"10.1055/s-0043-1776908","DOIUrl":"10.1055/s-0043-1776908","url":null,"abstract":"<p><strong>Background: </strong>Sickle cell disorder (SCD) is a hereditary blood disease characterized by an abnormality in the oxygen-carrying protein hemoglobin present in red blood cells. Genetic abnormality causes these cells to become sickle-shaped, with shorter lifespan. Vaso-occlusive crisis is a major symptom of SCD: it is a sudden and severe episode of pain, and occurs when sickle-shaped cells block blood flow. This blockage can lead to tissue damage, inflammation and pain.</p><p><strong>Objectives: </strong>This case series aims to observe the clinical outcomes from prescribing individualized homeopathic medicines along with organopathic supportive medicine in the management of SCD through the analysis of case studies of six patients from a particularly vulnerable tribal group (PVTG) in India that manifests genetic predisposition for the disease.</p><p><strong>Method: </strong>The patients were administered individualized homeopathic and organopathic supportive medicines, after a comprehensive door-to-door survey and subsequent screening, conducted between October 2020 and May 2023 in the Dindori and Mandla districts of the central Indian state, Madhya Pradesh. Clinical symptoms, laboratory parameters including hemoglobin, along with scores from a visual analogue scale (VAS) for pain and from the World Health Organization Quality of Life (WHOQoL) Questionnaire, were determined.</p><p><strong>Results: </strong>Individualized homeopathic and organopathic supportive management led to improvements in clinical symptoms for all six patients. Laboratory test results showed a statistically significant increase in hemoglobin level associated with treatment. The VAS for pain indicated decreased pain frequency and severity. WHOQoL scores also improved, indicating enhanced well-being for each patient. No adverse effects were reported during treatment.</p><p><strong>Conclusion: </strong>This study suggests that individualized homeopathic medicine and organopathic supportive management have a beneficial role in managing SCD and may be valuable in the context of PVTGs in India. To establish a more comprehensive understanding of its efficacy, further studies should involve larger cohorts to allow for a thorough evaluation, including comparative analyses with standard therapies.</p>","PeriodicalId":13227,"journal":{"name":"Homeopathy","volume":" ","pages":"253-261"},"PeriodicalIF":1.2,"publicationDate":"2024-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139641965","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Association between Usage of Prophylactic AYUSH Medicines and Disease Severity in COVID-19 Patients: A Retrospective Cohort Study. COVID-19 患者使用预防性 AYUSH 药物与疾病严重程度之间的关系:回顾性队列研究
IF 16.4 4区 医学
Homeopathy Pub Date : 2024-11-01 Epub Date: 2024-05-07 DOI: 10.1055/s-0044-1779693
Anupriya Chaudhary, Debadatta Nayak, Swati Pandey, Vipul Shastri, Madhuri Kamble, Vidya Pendse, Vismay Prajapati, Brijesh Vaidya, Heenal Rohit, Swaroopa Beedmani, Nutan Presswala, Tejaswini Patole, Ramesh Bawaskar, Vaishali Shinde, Mohua Datta, Gunjan Rai, Umakanta Prusty, Partha Pratim Pal, Siva Prasad Goli, Amulya Ratna Sahoo, K C Muraleedharan, Pooja Prakash, Ashish Mahajan, Anuradha Singh, Reetha Krishnan, Navin Pawaskar, Amit Srivastava, Gouri Devi Ningthoujam, Ravi Kumar Sadarla, Ranjit Sonny, Liyi Karso, Subhamoy Sarkar, Sunil Prasad, Ashish Kumar Shrivastava, Avinash Kumar, Nitesh Kumar, Ch Raveendar, Bsj Raja Kumar, Vspk Sastry, Asha Dasari, K Samson Sundeep, Subhash Kaushik, Padmalaya Rath, Shweta Gautam, Ratan Chandra Shil, Trupti Laxmi Swain, G Ravi Chandra Reddy, S Pradeep, S Stevenson, Gurudev Choubey, Lipipushpa Debata, Anil Khurana
{"title":"Association between Usage of Prophylactic AYUSH Medicines and Disease Severity in COVID-19 Patients: A Retrospective Cohort Study.","authors":"Anupriya Chaudhary, Debadatta Nayak, Swati Pandey, Vipul Shastri, Madhuri Kamble, Vidya Pendse, Vismay Prajapati, Brijesh Vaidya, Heenal Rohit, Swaroopa Beedmani, Nutan Presswala, Tejaswini Patole, Ramesh Bawaskar, Vaishali Shinde, Mohua Datta, Gunjan Rai, Umakanta Prusty, Partha Pratim Pal, Siva Prasad Goli, Amulya Ratna Sahoo, K C Muraleedharan, Pooja Prakash, Ashish Mahajan, Anuradha Singh, Reetha Krishnan, Navin Pawaskar, Amit Srivastava, Gouri Devi Ningthoujam, Ravi Kumar Sadarla, Ranjit Sonny, Liyi Karso, Subhamoy Sarkar, Sunil Prasad, Ashish Kumar Shrivastava, Avinash Kumar, Nitesh Kumar, Ch Raveendar, Bsj Raja Kumar, Vspk Sastry, Asha Dasari, K Samson Sundeep, Subhash Kaushik, Padmalaya Rath, Shweta Gautam, Ratan Chandra Shil, Trupti Laxmi Swain, G Ravi Chandra Reddy, S Pradeep, S Stevenson, Gurudev Choubey, Lipipushpa Debata, Anil Khurana","doi":"10.1055/s-0044-1779693","DOIUrl":"10.1055/s-0044-1779693","url":null,"abstract":"<p><strong>Background: </strong>Prior vaccination is often studied for its impact on individuals' post-infection prognosis. Ayurveda, Yoga, Unani, Siddha and Homeopathy (AYUSH) medicines, advised by the Government of India as prophylaxis during the first wave of the coronavirus disease 2019 (COVID-19) pandemic, were consumed by the masses in 2020. A study was therefore undertaken to observe any association between the prior usage of AYUSH prophylactic medicines and post-infection severity as reported by recovered COVID-19 individuals.</p><p><strong>Methods: </strong>This was a retrospective, multi-centre, cohort study conducted in 21 cities of India from 5th August to 30th November 2020. Data from recovered COVID-19 patients, of either sex or any age, captured information about AYUSH prophylactic medicines intake prior to infection, disease severity, symptomatology, duration of complaints, etc. The study participants were grouped into AYUSH intake and non-intake. Primary composite outcome was the disease clinical course. Secondary clinical outcomes were the rate of and time to clinical recovery.</p><p><strong>Results: </strong>Data of 5,023 persons were analysed. Ayurveda or homeopathic prophylactic medicines were consumed by more than half of the study participants: that is, 56.85% (<i>n</i> = 1,556) and 56.81% (<i>n</i> = 1,555) respectively. The overall adjusted protective effect (PE) of AYUSH prophylactic intake against moderate/severe forms of COVID-19 disease was 56.7% (95% confidence interval [CI], 48.7 to 63.50; <i>p</i> < 0.001). Adjusted PE for homeopathy and Siddha was 52.9% (95% CI, 42.30 to 61.50; <i>p</i> < 0.001) and 59.8% (95% CI, 37.80 to 74.10; <i>p</i> < 0.001), respectively. A statistically significant association was found between AYUSH prophylactic medicine intake and clinical recovery more frequently by the 3rd day of illness (χ<sup>2</sup> = 9.01; <i>p</i> = 0.002). Time to resolution of symptoms in the AYUSH intake group was on average 0.3 days earlier than in the non-intake group (<i>p</i> = 0.002).</p><p><strong>Conclusion: </strong>AYUSH prophylactics were associated with statistically significant levels of protection against COVID-19 disease severity. Amongst these, previous intake of homeopathy or Siddha medicines was associated with some protection against moderate/severe illness and with a somewhat quicker clinical recovery. Prospective studies with experimental research design are needed to validate the findings of this study.</p><p><strong>Study registration: </strong>Clinical Trials Registry-India (CTRI/2020/08/027000).</p>","PeriodicalId":13227,"journal":{"name":"Homeopathy","volume":" ","pages":"211-222"},"PeriodicalIF":16.4,"publicationDate":"2024-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11493470/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140876325","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Homeopathic Pyrogenium Ointment as Adjuvant in Treatment of Traumatic and Infected Myiasis by Cochliomyia Hominivorax (Diptera: Calliphoridae) in Sheep: A Case Series. 顺势疗法火碱软膏作为辅助药物治疗绵羊的外伤性和感染性绵羊蜱螨病(Diptera: Calliphoridae):病例系列。
IF 1.2 4区 医学
Homeopathy Pub Date : 2024-11-01 Epub Date: 2024-03-28 DOI: 10.1055/s-0043-1778066
Giuliano Pereira de Barros, Denise Pereira Leme, Patrizia Ana Bricarello
{"title":"Homeopathic Pyrogenium Ointment as Adjuvant in Treatment of Traumatic and Infected Myiasis by Cochliomyia Hominivorax (Diptera: Calliphoridae) in Sheep: A Case Series.","authors":"Giuliano Pereira de Barros, Denise Pereira Leme, Patrizia Ana Bricarello","doi":"10.1055/s-0043-1778066","DOIUrl":"10.1055/s-0043-1778066","url":null,"abstract":"<p><strong>Background: </strong>The blowfly <i>Cochliomyia hominivorax</i> (Diptera: Calliphoridae) causes traumatic myiasis in farm animals, with deeply embedded larvae that lead to serious tissue damage and sometimes death. Treating this form of myiasis is difficult, often resulting in poor outcomes. As a homeopathic preparation that can mimic traumatic myiasis symptoms, <i>Pyrogenium</i> could potentially supplement treatment. This study aimed to describe the adjuvant effect that a <i>Pyrogenium</i> ointment might have in the treatment of sheep with traumatic myiasis.</p><p><strong>Patients: </strong>The study reports a homeopathic adjuvant treatment with <i>Pyrogenium</i> 12cH ointment in six sheep with traumatic and infected myiasis. Daily clinical examinations were performed to monitor the evolution of the health of animals. <i>Pyrogenium</i> 12cH ointment was applied topically on the wounds, after cleaning and mechanical removal of the larvae from the lesion. Blood samples were collected for blood counts, and wound exudate samples were obtained for bacteriological examination before and after wound treatment.</p><p><strong>Results: </strong>The ointment of <i>Pyrogenium</i> 12cH limited the development of parasitic larvae and was associated with the repair of tissue losses resulting from the myiases and with subsequent wound healing, together with control of fever and local inflammation.</p><p><strong>Conclusion: </strong>Homeopathic <i>Pyrogenium</i> 12cH, formulated as an ointment, may be a useful new and adjuvant therapeutic option for treating traumatic and infected myiasis in animals.</p>","PeriodicalId":13227,"journal":{"name":"Homeopathy","volume":" ","pages":"262-273"},"PeriodicalIF":1.2,"publicationDate":"2024-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140318200","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
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